| DrugBank ID |
Name |
Formula |
Weight |
DB01232
|
Saquinavir |
C38H50N6O5 |
670.8408 |
| Saquinavir Saquinavir is a protease inhibitor with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Protease inhibitors block the part of HIV called protease. HIV-1 protease is an ... |
DB00238
|
Nevirapine |
C15H14N4O |
266.2979 |
| ... This combination presents an increased risk of toxicity
Saquinavir Decreases the effect of saquinavir
Simvastatin The NNRT inhibitor increases the effect and toxicity of the statin
St. John's ... |
DB00625
|
Efavirenz |
C14H9ClF3NO2 |
315.6750 |
| ... agent increases the effect and toxicity of benzodiazepine
Saquinavir Efavirenz decreases the effect of saquinavir
Simvastatin The NNRT inhibitor increases the effect and toxicity of the statin
St. |
DB01264
|
Darunavir |
C27H37N3O7S |
547.6640 |
| ... in lidocaine levels
Lopinavir Decreased levels of darunavir
Saquinavir Decreased levels of darunavir Take with food - better absorption (+30%). [(3R,3aS,6aR)-2,3,3a,4,5,6a-hexahydrofuro[5,4-b ... |
DB02703
|
Fusidic Acid |
C31H48O6 |
516.7092 |
| ... inhibitor increases the effect and toxicity of fusidic acid
Saquinavir The protease inhibitor increases the effect and toxicity of fusidic acid
Simvastatin Increased risk of myopathy ... |
DB00705
|
Delavirdine |
C22H28N6O3S |
456.5610 |
| ... the effect of ritonavir
Saquinavir Increases the effect of saquinavir and hepatic toxicity
Simvastatin The NNRT inhibitor increases the effect and toxicity of the statin
St. John's Wort St ... |
DB00690
|
Flurazepam |
C21H23ClFN3O |
387.8780 |
| ... protease inhibitor increases the effect of the benzodiazepine
Saquinavir The protease inhibitor increases the effect of the benzodiazepine
Voriconazole The imidazole increases the effect of ... |
DB01068
|
Clonazepam |
C15H10ClN3O3 |
315.7110 |
| ... protease inhibitor increases the effect of the benzodiazepine
Saquinavir The protease inhibitor increases the effect of the benzodiazepine
St. John's Wort St. John's Wort could reduce the ... |
DB01076
|
Atorvastatin |
C33H35FN2O5 |
558.6398 |
| ... Ritonavir increases the effect and toxicity of the statin
Saquinavir Saquinavir increases the effect and toxicity of atorvastatin
Tacrolimus Tacrolimus increases the effect and toxicity of the ... |
DB00475
|
Chlordiazepoxide |
C16H14ClN3O |
299.7550 |
| ... protease inhibitor increases the effect of the benzodiazepine
Saquinavir The protease inhibitor increases the effect of the benzodiazepine
Voriconazole The imidazole increases the effect of ... |
DB00530
|
Erlotinib |
C22H23N3O4 |
393.4357 |
| ... This CYP3A4 inhibitor increases levels/toxicity of erlotinib
Saquinavir This CYP3A4 inhibitor increases levels/toxicity of erlotinib
St. John's Wort Decreased levels/effect of erlotinib ... |
DB00628
|
Clorazepate |
C16H11ClN2O3 |
314.7230 |
| ... protease inhibitor increases the effect of the benzodiazepine
Saquinavir The protease inhibitor increases the effect of the benzodiazepine
Voriconazole The imidazole increases the effect of ... |
DB00813
|
Fentanyl |
C22H28N2O |
336.4705 |
| ... increases the effect and toxicity of fentanyl/alfentanyl
Saquinavir The protease inhibitor increases the effect and toxicity of fentanyl
Voriconazole The imidazole increases levels/toxicity of ... |
DB01215
|
Estazolam |
C16H11ClN4 |
294.7380 |
| ... protease inhibitor increases the effect of the benzodiazepine
Saquinavir The protease inhibitor increases the effect of the benzodiazepine
Voriconazole The imidazole increases the effect of ... |
DB00615
|
Rifabutin |
C46H62N4O11 |
847.0047 |
| ... Ritonavir Rifabutin decreases the effect of ritonavir
Saquinavir Rifabutin decreases the effect of saquinavir
Simvastatin The rifamycin decreases the effect of the statin drug
Sirolimus The ... |
DB01048
|
Abacavir |
C14H18N6O |
286.3323 |
| The antiviral response should be closely monitored.
Saquinavir The serum concentration of Abacavir may be decreased by protease inhibitors such as Saquinavir. The antiviral response should be ... |
DB00243
|
Ranolazine |
C24H33N3O4 |
427.5365 |
| ... Ritonavir Increased levels of ranolazine - risk of toxicity
Saquinavir Increased levels of ranolazine - risk of toxicity
Simvastatin Ranolazine increases the statin level
Sotalol Possible ... |
DB00404
|
Alprazolam |
C17H13ClN4 |
308.7650 |
| ... protease inhibitor increases the effect of the benzodiazepine
Saquinavir The protease inhibitor increases the effect of the benzodiazepine
St. John's Wort St. John's Wort could reduce the ... |
DB00637
|
Astemizole |
C28H31FN4O |
458.5703 |
| ... Ritonavir Increased risk of cardiotoxicity and arrhythmias
Saquinavir Increased risk of cardiotoxicity and arrhythmias
Sparfloxacin Increased risk of cardiotoxicity and arrhythmias ... |
DB00700
|
Eplerenone |
C24H30O6 |
414.4914 |
| ... inhibitor increases the effect and toxicity of eplerenone
Saquinavir This CYP3A4 inhibitor increases the effect and toxicity of eplerenone
Spironolactone This association presents an increased ... |