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Search for "Simvastatin" returned 34 results

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DrugBank ID	Name	Formula	Weight
DB00641	Simvastatin	C25H38O5	418.5662
	Inegy (Simvastatin + Ezetimibe) Simvastatin Simvastatin, the methylated form of lovastatin, is an oral antilipemic agent which inhibits HMG-CoA reductase. simvastatin is used in the treatment of ...
DB00175	Pravastatin	C23H36O7	424.5277
	... 1-yl]-3,5-dihydroxyheptanoic acid C01844 Like lovastatin and simvastatin, pravastatin inhibits hydroxymethylglutaryl-CoA (HMG-CoA) reductase. As HMG-CoA is necessary for the intracellular ...
DB00973	Ezetimibe	C24H21F2NO3	409.4252
	Inegy (Simvastatin + Ezetimibe) Ezetimibe Ezetimibe is in a class of lipid-lowering compounds that selectively inhibits the intestinal absorption of cholesterol and related phytosterols. Ezetimibe ...
DB01095	Fluvastatin	C24H26FNO4	411.4659
	Although similar to lovastatin, simvastatin, and pravastatin, Fluvastatin has a shorter half-life, no active metabolites, extensive protein binding, and minimal CSF penetration. PA449688 98 ...
DB00343	Diltiazem	C22H26N2O4S	414.5180
	... of diltiazem Ritonavir Ritonavir increases diltiazem levels Simvastatin Increases the effect and toicity of simvastatin Sirolimus Increases the effect and toxicity of sirolimus Tacrolimus ...
DB00238	Nevirapine	C15H14N4O	266.2979
	... risk of toxicity Saquinavir Decreases the effect of saquinavir Simvastatin The NNRT inhibitor increases the effect and toxicity of the statin St. John's Wort St. John's Wort decreases ...
DB01241	Gemfibrozil	C15H22O3	250.3334
	... Rosuvastatin possibly increases the effect of the fibrate Simvastatin Increased risk of myopathy/rhabdomyolysis Ursodeoxycholic acid The fibric acid derivative decreases the effect of ursodiol ...
DB02703	Fusidic Acid	C31H48O6	516.7092
	... inhibitor increases the effect and toxicity of fusidic acid Simvastatin Increased risk of myopathy/rhabdomyolysis Take with food to reduce irritation. (2Z)-2-[(3R,4S,5S,8S,9S,10S,11R,13R,14S ...
DB01039	Fenofibrate	C20H21ClO4	360.8310
	... Rosuvastatin possibly increases the effect of the fibrate Simvastatin Increased risk of myopathy/rhabdomyolysis Ursodeoxycholic acid The fibric acid derivative decreases the effect of ursodiol ...
DB01394	Colchicine	C22H25NO6	399.4370
	... Increased risk of rhabdomyolysis with this combination Simvastatin Increased risk of rhabdomyolysis with this combination Telithromycin Severe colchicine toxicity can occur Troleandomycin ...
DB00559	Bosentan	C27H29N5O6S	551.6140
	... Norethindrone Decreases the effect of contraceptive Simvastatin Bosentan could decrease the statin effect Voriconazole This imidazole increases the effect and toxicity of bosentan Warfarin ...
DB00243	Ranolazine	C24H33N3O4	427.5365
	... Saquinavir Increased levels of ranolazine - risk of toxicity Simvastatin Ranolazine increases the statin level Sotalol Possible additive effect on QT prolongation Telithromycin Increased ...
DB00625	Efavirenz	C14H9ClF3NO2	315.6750
	... Saquinavir Efavirenz decreases the effect of saquinavir Simvastatin The NNRT inhibitor increases the effect and toxicity of the statin St. John's Wort St. John's Wort decreases the ...
DB00619	Imatinib	C29H31N7O	493.6027
	... of pimozide Rifampin Rifampin decreases levels of imatinib Simvastatin Imatinib increases the effect and toxicity of statin St. John's Wort St. John's Wort decreases levels of imatinib ...
DB00705	Delavirdine	C22H28N6O3S	456.5610
	... Increases the effect of saquinavir and hepatic toxicity Simvastatin The NNRT inhibitor increases the effect and toxicity of the statin St. John's Wort St. John's Wort decreases the ...
DB01118	Amiodarone	C25H29I2NO3	645.3116
	... inhibitor increases the effect and toxicity of amiodarone Simvastatin Increased risk of rhabdomyolysis Sparfloxacin Increased risk of cardiotoxicity and arrhythmias Telithromycin Increased ...
DB01149	Nefazodone	C25H32ClN5O2	470.0070
	... CNS adverse effects Sibutramine Risk of serotoninergic syndrome Simvastatin Nefazodone increases the effect and toxicity of the statin drug Solifenacin This potent CYP3A4 inhibitor slows ...
DB00196	Fluconazole	C13H12F2N6O	306.2708
	... of rifabutin Rifampin Decreases the effect of imidazole Simvastatin Increased risk of myopathy/rhabdomyolysis Tacrolimus Increases the effect of the immunosuppressant Terfenadine Increased ...
DB00615	Rifabutin	C46H62N4O11	847.0047
	... Saquinavir Rifabutin decreases the effect of saquinavir Simvastatin The rifamycin decreases the effect of the statin drug Sirolimus The rifamycin decreases the effect of sirolimus Sunitinib ...
DB00701	Amprenavir	C25H35N3O6S	505.6270
	... inhibitor increases the effect and toxicity of sildenafil Simvastatin Amprenavir can possibly increase the statin toxicity St. John's Wort St. John's Wort decreases the effect of indinavir ...

Showing 1-20 out of 34

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This project is supported by Genome Alberta & Genome Canada, a not-for-profit organization that is leading Canada's national genomics strategy with $600 million in funding from the federal government. This project is also supported in part by GenomeQuest, Inc., an enterprise genomic information company serving the life science community.