| DrugBank ID |
Name |
Formula |
Weight |
DB00421
|
Spironolactone |
C24H32O4S |
416.5730 |
| ... Spironolactone Spironolactone Pathway SMP00134 Spironolactone is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called ... |
DB00700
|
Eplerenone |
C24H30O6 |
414.4914 |
| ... Eplerenone, an aldosterone receptor antagonist similar to spironolactone, has been shown to produce sustained increases in plasma renin and serum aldosterone, consistent with inhibition of the ... |
DB01395
|
Drospirenone |
C24H30O3 |
366.4932 |
| ... Drospirenone is a synthetic progestin that is an analog to spironolactone. It is found in a number of birth control formulations. Drospirenone differs from other synthetic progestins in that ... |
DB00648
|
Mitotane |
C14H10Cl4 |
320.0410 |
| ... Mitotane decreases the anticoagulant effect
Spironolactone Spironolactone antagonizes the effect of mitotane
Warfarin Mitotane decreases the anticoagulant effect Take without regard to meals ... |
DB00594
|
Amiloride |
C6H8ClN7O |
229.6270 |
| The risk is high in concurrent use of ACE inhibitors or spironolactone. Patients are also advised not to use potassium-containing salt replacements. PA448368 16231 9039 APRD00790
EXPT00514 AMR ... |
DB01340
|
Cilazapril |
C22H33N3O6 |
435.5139 |
| ... levels of lithium
Potassium Increased risk of hyperkaliemia
Spironolactone Increased risk of hyperkaliemia
Tizanidine Tizanidine increases the risk of hypotension with the ACE inhibitor ... |
DB01344
|
Polystyrene sulfonate |
C8H7CaO3S |
223.2820 |
| ... impairment
Potassium Risk of alkalosis in renal impairment
Spironolactone Risk of alkalosis in renal impairment
Triamterene Antagonism of action
Triamterene Antagonism of action Avoid calcium ... |
DB00178
|
Ramipril |
C23H32N2O5 |
416.5106 |
| ... levels of lithium
Potassium Increased risk of hyperkaliemia
Spironolactone Increased risk of hyperkaliemia
Tizanidine Tizanidine increases the risk of hypotension with the ACE inhibitor ... |
DB00492
|
Fosinopril |
C30H46NO7P |
563.6625 |
| ... levels of lithium
Potassium Increased risk of hyperkaliemia
Spironolactone Increased risk of hyperkaliemia
Tizanidine Tizanidine increases the risk of hypotension with the ACE inhibitor ... |
DB00584
|
Enalapril |
C20H28N2O5 |
376.4467 |
| ... hyperkaliemia
Rifampin Rifampin reduces the efefct of enalapril
Spironolactone Increased risk of hyperkaliemia
Tizanidine Tizanidine increases the risk of hypotension with the ACE inhibitor ... |
DB00678
|
Losartan |
C22H23ClN6O |
422.9110 |
| ... Rifampin Rifampin decreases the effect of losartan
Spironolactone Increased risk of hyperkaliemia
Triamterene Increased risk of hyperkaliemia Take without regard to meals. Take at same time ... |
DB00722
|
Lisinopril |
C21H31N3O5 |
405.4879 |
| ... levels of lithium
Potassium Increased risk of hyperkaliemia
Spironolactone Increased risk of hyperkaliemia
Tizanidine Tizanidine increases the risk of hypotension with the ACE inhibitor ... |
DB00796
|
Candesartan |
C24H20N6O3 |
440.4540 |
| ... levels of lithium
Potassium Increased risk of hyperkaliemia
Spironolactone Increased risk of hyperkaliemia
Triamterene Increased risk of hyperkaliemia Administer on a regular basis, at about ... |
DB00881
|
Quinapril |
C25H30N2O5 |
438.5161 |
| ... levels of lithium
Potassium Increased risk of hyperkaliemia
Spironolactone Increased risk of hyperkaliemia
Tetracycline Quinapril can reduce the absorption of tetracycline
Tizanidine ... |
DB01029
|
Irbesartan |
C25H28N6O |
428.5294 |
| ... levels of lithium
Potassium Increased risk of hyperkaliemia
Spironolactone Increased risk of hyperkaliemia
Triamterene Increased risk of hyperkaliemia Take without regard to meals. 2-butyl-3 ... |
DB01197
|
Captopril |
C9H15NO3S |
217.2850 |
| ... levels of lithium
Potassium Increased risk of hyperkaliemia
Spironolactone Increased risk of hyperkaliemia
Tizanidine Tizanidine increases the risk of hypotension with the ACE inhibitor ... |
DB00542
|
Benazepril |
C24H28N2O5 |
424.4895 |
| ... levels of lithium
Potassium Increased risk of hyperkaliemia
Spironolactone Increased risk of hyperkaliemia
Tizanidine Tizanidine increases the risk of hypotension with the ACE inhibitor ... |
DB00790
|
Perindopril |
C19H32N2O5 |
368.4678 |
| ... levels of lithium
Potassium Increased risk of hyperkaliemia
Spironolactone Increased risk of hyperkaliemia
Tizanidine Tizanidine increases the risk of hypotension with the ACE inhibitor ... |
DB00876
|
Eprosartan |
C23H24N2O4S |
424.5130 |
| ... levels of lithium
Potassium Increased risk of hyperkaliemia
Spironolactone Increased risk of hyperkaliemia
Triamterene Increased risk of hyperkaliemia Take without regard to meals. 4-[[2-butyl ... |
DB01345
|
Potassium |
K |
39.0983 |
| ... risk of hyperkaliemia
Spirapril Increased risk of hyperkaliemia
Spironolactone Increased risk of hyperkaliemia
Tasosartan Increased risk of hyperkaliemia
Telmisartan Increased risk of ... |