| DrugBank ID |
Name |
Formula |
Weight |
DB00682
|
Warfarin |
C19H16O4 |
308.3279 |
| Warfarin Warfarin Pathway SMP00268 Warfarin, a coumarin anticoagulant, is a racemic mixture of two active isomers. It is used in the prevention and treatment of thromboembolic disease including ... |
DB01418
|
Acenocoumarol |
C19H15NO6 |
353.3255 |
| Its actions and uses are similar to those of warfarin. (From Martindale, The Extra Pharmacopoeia, 30th ed, p233) PA452632 9052 10321722 Acenocoumarin
Acenocoumarolum [inn-latin]
Nicoumalone ... |
DB00498
|
Phenindione |
C15H10O2 |
222.2387 |
| Phenindione has actions similar to warfarin, but it is now rarely employed because of its higher incidence of severe adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p234 ... |
DB04898
|
Ximelagatran |
C24H35N5O5 |
473.5652 |
| ... drug interaction, and monitoring issues associated with warfarin therapy. In 2006, its manufacturer AstraZeneca announced that it would not attempt to market ximelagatran after reports of ... |
DB00569
|
Fondaparinux sodium |
C31H43N3Na10O49S8 |
1728.0820 |
| ... acute pulmonary embolism when administered in conjunction with warfarin. Fondaparinux does not inactivate thrombin (activated Factor II) and has no known effect on platelet function. At the ... |
DB00975
|
Dipyridamole |
C24H40N8O4 |
504.6256 |
| ... is combined with other anticoagulant drugs, such as warfarin, to prevent thrombosis in patients with valvular or vascular disorders. Dipyridamole is also used in myocardial perfusion imaging ... |
DB01420
|
Testosterone Propionate |
C22H32O3 |
344.4877 |
| Monitor for changes in the therapeutic effect of Warfarin if Testosterone is initiated, discontinued or dose changed. [(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17 ... |
DB01157
|
Trimetrexate |
C19H23N5O3 |
369.4176 |
| Warfarin The anticoagulant effect of Warfarin, a Vitamin K antagonist, may be altered by antineoplastics such as Trimetrexate. Monitor for changes in the anticoagulant effects of warfarin and ... |
DB00894
|
Testolactone |
C19H24O3 |
300.3921 |
| Monitor for changes in the therapeutic effect of Warfarin if Testolactone is initiated, discontinued or dose changed. (4aS,4bR,10aR,10bS,12aS)-10a,12a-dimethyl-4,4a,4b,5,6,10b,11,12-octahydro-3H ... |
DB00624
|
Testosterone |
C19H28O2 |
288.4244 |
| Monitor for changes in the therapeutic effect of Warfarin if Testosterone is initiated, discontinued or dose changed. (8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16 ... |
DB00509
|
Dextrothyroxine |
C15H11I4NO4 |
776.8700 |
| ... Digoxin The thyroid hormone decreases the effect of digoxin
Warfarin Thyroid hormones increase the anticoagulant effect Take without regard to meals. 2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy ... |
DB01437
|
Glutethimide |
C13H15NO2 |
217.2637 |
| ... antagonism of action
Rivastigmine Possible antagonism of action
Warfarin The agent decreases the anticoagulant effect Avoid alcohol.
Take without regard to meals. 3-ethyl-3-phenylpiperidine-2 ... |
DB00189
|
Ethchlorvynol |
C7H9ClO |
144.5990 |
| ... Dicumarol Ethchlorvynol decreases the anticoagulant effect
Warfarin Ethchlorvynol decreases the anticoagulant effect Avoid alcohol
Take with food to reduce irritation. 1-chloro-3-ethylpent-1 ... |
DB00499
|
Flutamide |
C11H11F3N2O3 |
276.2118 |
| ... effect
Dicumarol Flutamide increases the anticoagulant effect
Warfarin Flutamide increases the anticoagulant effect Take without regard to meals. 2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl ... |
DB00648
|
Mitotane |
C14H10Cl4 |
320.0410 |
| ... Spironolactone antagonizes the effect of mitotane
Warfarin Mitotane decreases the anticoagulant effect Take without regard to meals. 1-chloro-4-[2,2-dichloro-1-(2-chlorophenyl)ethyl]benzene ... |
DB00749
|
Etodolac |
C17H21NO3 |
287.3535 |
| ... The NSAID increases the effect and toxicity of methotrexate
Warfarin The NSAID increases the anticoagulant effect Avoid alcohol.
Take with food. 2-(1,8-diethyl-4,9-dihydro-3H-pyrano[3,4-b ... |
DB00806
|
Pentoxifylline |
C13H18N4O3 |
278.3070 |
| ... increases the effect and toxicity of theophylline
Warfarin Pentoxifylline increases the anticoagulant effect Take with food to reduce irritation. Limit caffeine intake. 3,7-dimethyl-1-(5 ... |
DB00814
|
Meloxicam |
C14H13N3O4S2 |
351.4010 |
| ... effect
Lithium Meloxicam increases serum levels of lithium
Warfarin Meloxicam increases the anticoagulant effect Take without regard to meals. (3E)-3-[hydroxy-[(5-methyl-1,3-thiazol-2-yl)amino ... |
DB01330
|
Cefotetan |
C17H17N7O8S4 |
575.6190 |
| ... of nephrotoxicity
Tobramycin Increased risk of nephrotoxicity
Warfarin The cephalosporin increases the anticoagulant effect Avoid alcohol as it can cause a disulfiram effect. (7S)-7-[[4-(1 ... |
DB01331
|
Cefoxitin |
C16H17N3O7S2 |
427.4520 |
| ... of nephrotoxicity
Tobramycin Increased risk of nephrotoxicity
Warfarin The cephalosporin increases the anticoagulant effect (6R,7S)-3-(carbamoyloxymethyl)-7-methoxy-8-oxo-7-[(2-thiophen-2 ... |