Showing BioInteractions for Methionine (DB00134)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Methionine is a Glutamine synthetase inhibitor | ||
| 1 | Glutamine synthetase inhibitors | Diazoxide, Ethyl biscoumacetate, Pegvisomant, Picrotoxin |
| 2 | Glutamine synthetase inducers | Capsaicin, Ceftriaxone |
| 3 | Glutamine synthetase substrates | Ammonia |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Methionine is a Methylenetetrahydrofolate reductase inhibitor | ||
| 1 | Methylenetetrahydrofolate reductase cofactors | Cyanocobalamin, Riboflavin, Tetrahydrofolic acid |
| 2 | Methylenetetrahydrofolate reductase substrates | Benazepril, Fluorouracil, Folic acid, Menadione, Methotrexate |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Methionine is a S-adenosylmethionine synthase isoform type-2 substrate | ||
| 1 | S-adenosylmethionine synthase isoform type-2 cofactors | Ademetionine |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Methionine is a Methionine-R-sulfoxide reductase B2, mitochondrial substrate | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Methionine is a S-adenosylmethionine synthase isoform type-1 substrate | ||
| 1 | S-adenosylmethionine synthase isoform type-1 cofactors | Ademetionine |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Methionine is a Methionine-R-sulfoxide reductase B1 substrate | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Methionine is a Mitochondrial peptide methionine sulfoxide reductase substrate | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Methionine is a Methionine--tRNA ligase, cytoplasmic substrate | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Methionine is a Methionine--tRNA ligase, mitochondrial substrate | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Methionine is a Methionine adenosyltransferase 2 subunit beta substrate | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Methionine is a Monocarboxylate transporter 10 inhibitor | ||
| 1 | Monocarboxylate transporter 10 inhibitors | Alanine, Arginine, Asparagine, Aspartic acid, Cysteine, Cystine, D-Alanine, D-Leucine, D-Phenylalanine, D-Serine, D-Tryptophan, D-Tyrosine, Droxidopa, Glutamic acid, Glycine, Histidine, Isoleucine, L-Glutamine, Lactic acid, Leucine, Levodopa, Liothyronine, Liotrix, Lysine, Phenylalanine, Proline, Pyruvic acid, Serine, Threonine, Tryptophan, Tyrosine, Valine |
| 2 | Monocarboxylate transporter 10 substrates | 2-aminoisobutyric acid, beta-Alanine, D-Phenylalanine, Glutamic acid, Glycine, Histidine, Lactic acid, Lysine, Pyruvic acid |