Showing BioInteractions for Glutamic acid (DB00142)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glutamic acid is a Glutamate--cysteine ligase catalytic subunit substrate | ||
| 1 | Glutamate--cysteine ligase catalytic subunit inducers | alpha-Tocopherol succinate, D-alpha-Tocopherol acetate, Vitamin E |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glutamic acid is a Glutamate dehydrogenase 2, mitochondrial substrate | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glutamic acid is a Aspartate aminotransferase substrate | ||
| 1 | Aspartate aminotransferase cofactors | Pyridoxal phosphate |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glutamic acid is a Alanine aminotransferase 2 substrate | ||
| 1 | Alanine aminotransferase 2 cofactors | Pyridoxal phosphate |
| 2 | Alanine aminotransferase 2 inhibitors | Phenelzine |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glutamic acid is a Monocarboxylate transporter 10 substrate | ||
| 1 | Monocarboxylate transporter 10 inhibitors | Alanine, Arginine, Asparagine, Aspartic acid, Cysteine, Cystine, D-Alanine, D-Leucine, D-Phenylalanine, D-Serine, D-Tryptophan, D-Tyrosine, Droxidopa, Glycine, Histidine, Isoleucine, L-Glutamine, Lactic acid, Leucine, Levodopa, Liothyronine, Liotrix, Lysine, Methionine, Phenylalanine, Proline, Pyruvic acid, Serine, Threonine, Tryptophan, Tyrosine, Valine |
| 2 | Monocarboxylate transporter 10 substrates | 2-aminoisobutyric acid, beta-Alanine, D-Phenylalanine, Glycine, Histidine, Lactic acid, Lysine, Pyruvic acid |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glutamic acid is a Monocarboxylate transporter 10 inhibitor | ||
| 1 | Monocarboxylate transporter 10 inhibitors | Alanine, Arginine, Asparagine, Aspartic acid, Cysteine, Cystine, D-Alanine, D-Leucine, D-Phenylalanine, D-Serine, D-Tryptophan, D-Tyrosine, Droxidopa, Glycine, Histidine, Isoleucine, L-Glutamine, Lactic acid, Leucine, Levodopa, Liothyronine, Liotrix, Lysine, Methionine, Phenylalanine, Proline, Pyruvic acid, Serine, Threonine, Tryptophan, Tyrosine, Valine |
| 2 | Monocarboxylate transporter 10 substrates | 2-aminoisobutyric acid, beta-Alanine, D-Phenylalanine, Glycine, Histidine, Lactic acid, Lysine, Pyruvic acid |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glutamic acid is a Monocarboxylate transporter 1 substrate | ||
| 1 | Monocarboxylate transporter 1 inhibitors | Acetoacetic acid, alpha-D-quinovopyranose, alpha-Ketoisovalerate, D-Lactic acid, gamma-Hydroxybutyric acid, Lactic acid, Niflumic acid, Probenecid, Pyruvic acid, Quercetin |
| 2 | Monocarboxylate transporter 1 substrates | Acetic acid, Acetoacetic acid, Aminohippuric acid, Arbaclofen Placarbil, D-Lactic acid, Foscarnet, Lactic acid, Methotrexate, Nateglinide, Niacin, Pravastatin, Pyruvic acid, Salicylic acid, Taurocholic acid, Valproic acid |
| 3 | Monocarboxylate transporter 1 antagonists | Mersalyl |