Showing BioInteractions for Glycine (DB00145)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glycine is a Glutathione synthetase substrate | ||
| 1 | Glutathione synthetase stimulators | Acetylcysteine |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glycine is a Glycine receptor subunit alpha-1 ligand | ||
| 1 | Glycine receptor subunit alpha-1 agonists | Desflurane, Ethanol, Isoflurane, Methoxyflurane, Sevoflurane, Taurine |
| 2 | Glycine receptor subunit alpha-1 antagonists | Atropine, Ginkgo biloba, Lindane, Picrotoxin, Thiocolchicoside |
| 3 | Glycine receptor subunit alpha-1 inhibitors | Zinc chloride, Zinc sulfate, unspecified form |
| 4 | Glycine receptor subunit alpha-1 potentiators | Enflurane |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glycine is a Serine--pyruvate aminotransferase substrate | ||
| 1 | Serine--pyruvate aminotransferase cofactors | Pyridoxal phosphate |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glycine is a Glycine receptor subunit beta ligand | ||
| 1 | Glycine receptor subunit beta antagonists | Lindane |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glycine is a Glycine receptor subunit alpha-3 ligand | ||
| 1 | Glycine receptor subunit alpha-3 agonists | Ivermectin, Taurine |
| 2 | Glycine receptor subunit alpha-3 antagonists | Lindane, Picrotoxin |
| 3 | Glycine receptor subunit alpha-3 potentiators | Cannabidiol |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glycine is a Glycine receptor subunit alpha-2 ligand | ||
| 1 | Glycine receptor subunit alpha-2 agonists | Ethanol, Taurine |
| 2 | Glycine receptor subunit alpha-2 antagonists | Lindane, Picrotoxin |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glycine is a Glycine N-methyltransferase substrate | ||
| 1 | Glycine N-methyltransferase cofactors | Ademetionine |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glycine is a Glycine amidinotransferase, mitochondrial substrate | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glycine is a Glutamate receptor ionotropic, NMDA 3B substrate | ||
| 1 | Glutamate receptor ionotropic, NMDA 3B antagonists | Halothane, Orphenadrine, Tenocyclidine |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glycine is a 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial substrate | ||
| 1 | 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial cofactors | Pyridoxal phosphate |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glycine is a 5-aminolevulinate synthase, nonspecific, mitochondrial substrate | ||
| 1 | 5-aminolevulinate synthase, nonspecific, mitochondrial cofactors | Pyridoxal phosphate |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glycine is a 5-aminolevulinate synthase, erythroid-specific, mitochondrial substrate | ||
| 1 | 5-aminolevulinate synthase, erythroid-specific, mitochondrial cofactors | Pyridoxal phosphate |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glycine is a Glycine--tRNA ligase substrate | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glycine is a Glutamate receptor ionotropic, NMDA 2A antagonist | ||
| 1 | Glutamate receptor ionotropic, NMDA 2A antagonists | Felbamate, Halothane, Meperidine, Tenocyclidine |
| 2 | Glutamate receptor ionotropic, NMDA 2A activators | Acetylcysteine |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glycine is a Bile acid-CoA:amino acid N-acyltransferase substrate | ||
| 1 | Bile acid-CoA:amino acid N-acyltransferase substrates | Taurine |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glycine is a N-arachidonyl glycine receptor substrate | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glycine is a Glutamate receptor ionotropic, NMDA 2C agonist | ||
| 1 | Glutamate receptor ionotropic, NMDA 2C antagonists | Meperidine, Tenocyclidine |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glycine is a Glycine N-acyltransferase substrate | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glycine is a Glycine N-acyltransferase-like protein 2 substrate | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glycine is a Glycine N-acyltransferase-like protein 1 substrate | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glycine is a Aminomethyltransferase, mitochondrial substrate | ||
| 1 | Aminomethyltransferase, mitochondrial cofactors | Tetrahydrofolic acid |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glycine is a Glycine dehydrogenase [decarboxylating], mitochondrial substrate | ||
| 1 | Glycine dehydrogenase [decarboxylating], mitochondrial cofactors | Pyridoxal phosphate |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glycine is a Dihydrolipoyl dehydrogenase, mitochondrial substrate | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glycine is a Glycine cleavage system H protein, mitochondrial substrate | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glycine is a Monocarboxylate transporter 10 substrate | ||
| 1 | Monocarboxylate transporter 10 inhibitors | Alanine, Arginine, Asparagine, Aspartic acid, Cysteine, Cystine, D-Alanine, D-Leucine, D-Phenylalanine, D-Serine, D-Tryptophan, D-Tyrosine, Droxidopa, Glutamic acid, Histidine, Isoleucine, L-Glutamine, Lactic acid, Leucine, Levodopa, Liothyronine, Liotrix, Lysine, Methionine, Phenylalanine, Proline, Pyruvic acid, Serine, Threonine, Tryptophan, Tyrosine, Valine |
| 2 | Monocarboxylate transporter 10 substrates | 2-aminoisobutyric acid, beta-Alanine, D-Phenylalanine, Glutamic acid, Histidine, Lactic acid, Lysine, Pyruvic acid |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glycine is a Monocarboxylate transporter 10 inhibitor | ||
| 1 | Monocarboxylate transporter 10 inhibitors | Alanine, Arginine, Asparagine, Aspartic acid, Cysteine, Cystine, D-Alanine, D-Leucine, D-Phenylalanine, D-Serine, D-Tryptophan, D-Tyrosine, Droxidopa, Glutamic acid, Histidine, Isoleucine, L-Glutamine, Lactic acid, Leucine, Levodopa, Liothyronine, Liotrix, Lysine, Methionine, Phenylalanine, Proline, Pyruvic acid, Serine, Threonine, Tryptophan, Tyrosine, Valine |
| 2 | Monocarboxylate transporter 10 substrates | 2-aminoisobutyric acid, beta-Alanine, D-Phenylalanine, Glutamic acid, Histidine, Lactic acid, Lysine, Pyruvic acid |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glycine is a Proton-coupled amino acid transporter 1 substrate | ||
| 1 | Proton-coupled amino acid transporter 1 substrates | Gaboxadol, Methotrexate, Spaglumic acid, Taurine, Vigabatrin |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glycine is a Vesicular inhibitory amino acid transporter substrate | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glycine is a Sodium- and chloride-dependent glycine transporter 2 substrate | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Glycine is a Sodium- and chloride-dependent glycine transporter 1 substrate | ||