Showing BioInteractions for Thiamine (DB00152)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.

	Interacting Group	Interacting Drugs
	Thiamine is a Thiamin pyrophosphokinase 1 substrate
1	Thiamin pyrophosphokinase 1 substrates	Thiamine

	Interacting Group	Interacting Drugs
	Thiamine is a Cytochrome P450 4B1 inducer
1	Cytochrome P450 4B1 inducers	Phenobarbital

	Interacting Group	Interacting Drugs
	Thiamine is a Thiamin pyrophosphokinase 1 substrate
1	Thiamin pyrophosphokinase 1 substrates	Thiamine

	Interacting Group	Interacting Drugs
	Thiamine is a Ectonucleoside triphosphate diphosphohydrolase 5 substrate

	Interacting Group	Interacting Drugs
	Thiamine is a Thiamine-triphosphatase substrate

	Interacting Group	Interacting Drugs
	Thiamine is a Solute carrier family 22 member 2 inhibitor
1	Solute carrier family 22 member 2 inhibitors	Abemaciclib, Amantadine, Amiloride, Aminohippuric acid, Amiodarone, Apalutamide, Baricitinib, Bupropion, Chlorpheniramine, Choline, Choline salicylate, Cimetidine, Cisplatin, Clopidogrel, Cocaine, Desipramine, Dexchlorpheniramine maleate, Dinoprostone, Diphenhydramine, Disopyramide, Dolutegravir, Dopamine, Dronedarone, Enasidenib, Erdafitinib, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Famotidine, Flurazepam, Grepafloxacin, Guanidine, Histamine, Imatinib, Imipramine, Isavuconazole, Lamotrigine, Lenvatinib, Levofloxacin, Linagliptin, Metformin, Methylene blue, Metoprolol, Nicotine, Norepinephrine, Osilodrostat, Oxprenolol, Pemigatinib, Phenformin, Phenoxybenzamine, Pimagedine, Probenecid, Procainamide, Progesterone, Propranolol, Quinacrine, Quinidine, Quinine, Rimegepant, Salmeterol, Tafenoquine, Tirbanibulin, Trilaciclib, Tucatinib, Ubrogepant, Vandetanib, Varenicline
2	Solute carrier family 22 member 2 substrates	Agmatine, Amantadine, Choline, Choline salicylate, Cimetidine, Cisplatin, Dalfampridine, Dofetilide, Dopamine, Epinephrine, Guanfacine, Histamine, Lamivudine, Linagliptin, Memantine, Metformin, Nafamostat, Norepinephrine, Oxaliplatin, Pramipexole, Ranitidine, Reserpine, Sulpiride, Terbutaline, Tetraethylammonium, Tipiracil, Varenicline

	Interacting Group	Interacting Drugs
	Thiamine is a Solute carrier family 22 member 1 substrate
1	Solute carrier family 22 member 1 substrates	Acetylcholine, Acyclovir, Agmatine, Amantadine, Buformin, Choline, Choline salicylate, Cimetidine, Codeine, Dexchlorpheniramine maleate, Dopamine, Epinephrine, Formoterol, Ganciclovir, Guanfacine, Imatinib, Lamivudine, Lamotrigine, Metformin, Nafamostat, Nintedanib, Norepinephrine, Pancuronium, Phenformin, Pramipexole, Prazosin, Quinine, Ranitidine, Rocuronium, Salmeterol, Spermidine, Spermine, Sulpiride, Tubocurarine
2	Solute carrier family 22 member 1 inhibitors	Acyclovir, Amantadine, Chlorpheniramine, Choline, Choline salicylate, Cimetidine, Clopidogrel, Codeine, Dacomitinib, Desipramine, Dexchlorpheniramine maleate, Disopyramide, Doxazosin, Dronedarone, Efavirenz, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Formoterol, Ganciclovir, Gilteritinib, Guanfacine, Guanidine, Indinavir, Lasmiditan, Levofloxacin, Linagliptin, Lurbinectedin, Nelfinavir, Nevirapine, Nicotine, Nintedanib, Osilodrostat, Palbociclib, Phenoxybenzamine, Pitolisant, Prazosin, Probenecid, Procainamide, Progesterone, Quinidine, Quinine, Ranitidine, Reserpine, Rucaparib, Salmeterol, Saquinavir, Tirbanibulin, Verapamil

	Interacting Group	Interacting Drugs
	Thiamine is a Solute carrier family 22 member 5 inhibitor
1	Solute carrier family 22 member 5 inhibitors	Acetylcholine, Aldosterone, Aminohippuric acid, Ampicillin, Arginine, Azidocillin, Benzylpenicillin, Cefadroxil, Cefalotin, Cefdinir, Cefepime, Cefixime, Cefradine, Ceftazidime, Cephalexin, Cephaloglycin, Choline, Choline salicylate, Cimetidine, Clonidine, Creatine, Cyclacillin, Dactinomycin, Desipramine, Diphenhydramine, Dopamine, Furosemide, Grepafloxacin, Guanidine, Histamine, Levamlodipine, Lidocaine, Lomefloxacin, Metamfetamine, Methacholine, Niacin, Nicotine, Norepinephrine, Norfloxacin, Ofloxacin, Probenecid, Procainamide, Quinidine, Quinine, Sparfloxacin, Valproic acid, Verapamil
2	Solute carrier family 22 member 5 substrates	Amphetamine, Formoterol, Ipratropium, Levocarnitine, Terbutaline, Tiotropium

	Interacting Group	Interacting Drugs
	Thiamine is a Thiamine transporter 1 substrate

	Interacting Group	Interacting Drugs
	Thiamine is a Thiamine transporter 2 substrate