Showing BioInteractions for Clotrimazole (DB00257)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.

	Interacting Group	Interacting Drugs
	Clotrimazole is a Intermediate conductance calcium-activated potassium channel protein 4 inhibitor
1	Intermediate conductance calcium-activated potassium channel protein 4 inhibitors	Halothane, Quinine

	Interacting Group	Interacting Drugs
	Clotrimazole is a Cytochrome P450 51 antagonist
1	Cytochrome P450 51 inhibitors	Bifonazole, Fluconazole, Luliconazole, Miconazole, Oxiconazole, Sertaconazole, Voriconazole
2	Cytochrome P450 51 antagonists	Econazole, Posaconazole, Terconazole, Tioconazole, Voriconazole

	Interacting Group	Interacting Drugs
	Clotrimazole is a Cytochrome P450 51 inhibitor
1	Cytochrome P450 51 inhibitors	Bifonazole, Fluconazole, Luliconazole, Miconazole, Oxiconazole, Sertaconazole, Voriconazole
2	Cytochrome P450 51 antagonists	Econazole, Posaconazole, Terconazole, Tioconazole, Voriconazole

	Interacting Group	Interacting Drugs
	Clotrimazole is a Nuclear receptor subfamily 1 group I member 2 activator
1	Nuclear receptor subfamily 1 group I member 2 binders	Docetaxel, Estradiol
2	Nuclear receptor subfamily 1 group I member 2 agonists	Dexamethasone, Dexamethasone acetate, Erlotinib, Ethinylestradiol, Nifedipine, Rifampicin, Rifaximin, Rilpivirine
3	Nuclear receptor subfamily 1 group I member 2 inducers	Paclitaxel
4	Nuclear receptor subfamily 1 group I member 2 activators	Carbamazepine, Ethotoin, Mephenytoin, Methylphenobarbital, Pentobarbital, Phenobarbital, Prasterone, Quercetin, Ritonavir, Sulfinpyrazone, Troleandomycin
5	Nuclear receptor subfamily 1 group I member 2 partial agonists	Bezafibrate, Clonazepam, Econazole, Fenofibrate, Fenofibric acid, Miconazole, Myrrh, Oxiconazole
6	Nuclear receptor subfamily 1 group I member 2 antagonists	Ketoconazole
7	Nuclear receptor subfamily 1 group I member 2 suppressors	Dovitinib

	Interacting Group	Interacting Drugs
	Clotrimazole is a Hydroxycarboxylic acid receptor 2 partial agonist
1	Hydroxycarboxylic acid receptor 2 agonists	Inositol nicotinate, Niacin

	Interacting Group	Interacting Drugs
	Clotrimazole is a Ergosterol inhibitor
1	Ergosterol antagonists	Candicidin
2	Ergosterol binders	Amphotericin B, Natamycin, Nystatin

	Interacting Group	Interacting Drugs
	Clotrimazole is a Cytochrome P450 2D6 inhibitor
1	Cytochrome P450 2D6 substrates	4-Methoxyamphetamine, 5-methoxy-N,N-dimethyltryptamine, Acebutolol, Acetaminophen, Almotriptan, Alogliptin, Alprenolol, Aminophenazone, Amitriptyline, Amoxapine, Amphetamine, Amprenavir, Anisodamine, Antipyrine, Aprindine, Arformoterol, Aripiprazole, Aripiprazole lauroxil, Arotinolol, Asenapine, Astemizole, Asunaprevir, Atenolol, Atomoxetine, Azelastine, Azimilide, Befunolol, Benzyl alcohol, Bepridil, Betaxolol, Bevantolol, Bicifadine, Bopindolol, Bortezomib, Brexpiprazole, Bucindolol, Bufuralol, Bupivacaine, Bupranolol, Buprenorphine, Buspirone, Butyrfentanyl, Caffeine, Cannabidiol, Cariprazine, Carteolol, Carvedilol, Celecoxib, Celiprolol, Cevimeline, Chloroquine, Chlorpheniramine, Chlorpromazine, Chlorzoxazone, Ciclesonide, Cilostazol, Cinnarizine, Citalopram, Clevidipine, Clomipramine, Clonidine, Cloranolol, Clozapine, Codeine, Cyclobenzaprine, Dacomitinib, Dapagliflozin, Dapoxetine, Darifenacin, Dasabuvir, Debrisoquine, Delavirdine, Desipramine, Deutetrabenazine, Dexchlorpheniramine, Dexchlorpheniramine maleate, Dexfenfluramine, Dextroamphetamine, Dextromethorphan, Dextropropoxyphene, Dihydrocodeine, Diltiazem, Diphenhydramine, Dolasetron, Domperidone, Donepezil, Dosulepin, Doxazosin, Doxepin, Dronedarone, Duloxetine, Elagolix, Eletriptan, Eliglustat, Enasidenib, Encainide, Enclomiphene, Encorafenib, Epanolol, Epinastine, Erlotinib, Esatenolol, Escitalopram, Esmirtazapine, Esmolol, Ethylmorphine, Fenfluramine, Fesoterodine, Flecainide, Flunarizine, Fluoxetine, Fluvastatin, Fluvoxamine, Formoterol, Fusidic acid, Galantamine, Gefitinib, Haloperidol, Hydrocodone, Hydroxychloroquine, Ibrutinib, Idarubicin, Iloperidone, Imatinib, Imipramine, Indenolol, Ipecac, Istradefylline, Ixazomib, Labetalol, Landiolol, Letermovir, Levobetaxolol, Levobunolol, Levomilnacipran, Lidocaine, Lisdexamfetamine, Lofexidine, Loperamide, Lopinavir, Loratadine, Lorcaserin, Lorpiprazole, Lysergic acid diethylamide, Maprotiline, Meclizine, Meperidine, Mephenytoin, Mepindolol, Mequitazine, Mesoridazine, Metamfetamine, Methadone, Methotrimeprazine, Methoxyflurane, Methylene blue, Metipranolol, Metoclopramide, Metoprolol, Mexiletine, Mianserin, Midodrine, Midomafetamine, Minaprine, Mirabegron, Mirtazapine, Moclobemide, Nabiximols, Nateglinide, Nebivolol, Nefazodone, Netupitant, Nevirapine, Nicergoline, Nicotine, Nortriptyline, Olanzapine, Oliceridine, Ondansetron, Opium, Osilodrostat, Oxamniquine, Oxprenolol, Oxycodone, Oxymorphone, Paliperidone, Palonosetron, Paroxetine, Penbutolol, Pentamidine, Perhexiline, Perospirone, Perphenazine, Phenacetin, Phenformin, Phenytoin, Pindolol, Piperazine, Pipotiazine, Pirfenidone, Pitolisant, Ponatinib, Practolol, Pralsetinib, Procainamide, Prochlorperazine, Progesterone, Promazine, Promethazine, Propacetamol, Propafenone, Propranolol, Quetiapine, Quinine, Ranolazine, Remdesivir, Remoxipride, Repinotan, Revefenacin, Ripretinib, Risperidone, Ritonavir, Rotigotine, Rucaparib, Rupatadine, Selegiline, Sertindole, Sertraline, Sildenafil, Simvastatin, Solifenacin, Sotalol, Sparteine, Tafenoquine, Talinolol, Tamoxifen, Tamsulosin, Tapentadol, Tegaserod, Terfenadine, Tertatolol, Tesmilifene, Tetrabenazine, Theophylline, Thioridazine, Ticlopidine, Timolol, Tiotropium, Tipranavir, Tolterodine, Trabectedin, Tramadol, Trazodone, Triclabendazole, Trimipramine, Umeclidinium, Umifenovir, Upadacitinib, Valbenazine, Venlafaxine, Vernakalant, Vilazodone, Vortioxetine, Yohimbine, Zolpidem, Zuclopenthixol
2	Cytochrome P450 2D6 inhibitors	1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine, Abemaciclib, Abiraterone, Acebutolol, Amiodarone, Amlodipine, Amodiaquine, Amoxapine, Artenimol, Asenapine, Asunaprevir, Atorvastatin, Azelastine, Bepridil, Berotralstat, Bicalutamide, Biperiden, Black cohosh, Buprenorphine, Bupropion, Cannabidiol, Celecoxib, Cerivastatin, Chloroquine, Chlorpheniramine, Chlorpromazine, Cimetidine, Cinacalcet, Cisapride, Citalopram, Clascoterone, Clemastine, Clinafloxacin, Clobazam, Clofazimine, Clomipramine, Clozapine, Cobicistat, Cocaine, Curcumin, Curcumin sulfate, Cyclosporine, Dacomitinib, Darifenacin, Darunavir, Delavirdine, Deramciclane, Desipramine, Desvenlafaxine, Dexchlorpheniramine, Dexchlorpheniramine maleate, Dexfenfluramine, Dexmedetomidine, Dextropropoxyphene, Diacerein, Dimethyl sulfoxide, Diphenhydramine, Dosulepin, Doxepin, Doxorubicin, Dronedarone, Duloxetine, Efavirenz, Elexacaftor, Eliglustat, Enasidenib, Entacapone, Epinastine, Escitalopram, Ethambutol, Etoricoxib, Everolimus, Fedratinib, Felodipine, Fenfluramine, Flecainide, Fluoxetine, Fluphenazine, Fluvoxamine, Fusidic acid, Gefitinib, Glycerol phenylbutyrate, Halofantrine, Haloperidol, Hydroxychloroquine, Hydroxyurea, Hydroxyzine, Imatinib, Imipramine, Indinavir, Indisulam, Iproniazid, Isavuconazole, Isoniazid, Ketoconazole, Labetalol, Lansoprazole, Lasmiditan, Lenvatinib, Lercanidipine, Lidocaine, Lisdexamfetamine, Lomustine, Loratadine, Lorcaserin, Lumefantrine, Manidipine, Medical Cannabis, Melperone, Menadione, Mepyramine, Methadone, Methimazole, Methotrimeprazine, Methylene blue, Metoclopramide, Metoprolol, Mibefradil, Miconazole, Midostaurin, Mifepristone, Mirabegron, Mizolastine, Moclobemide, Nabiximols, Naloxegol, Nefazodone, Nelfinavir, Nevirapine, Niacin, Nicardipine, Nicotinamide, Nifedipine, Nilotinib, Nortriptyline, Olanzapine, Omeprazole, Oritavancin, Orphenadrine, Osilodrostat, Ospemifene, Oxamniquine, Oxprenolol, Oxybutynin, Oxymetholone, Panobinostat, Paroxetine, Pazopanib, Peginterferon alfa-2b, Perhexiline, Perphenazine, Phenelzine, Phenylbutyric acid, Pimozide, Pindolol, Pipotiazine, Pitolisant, Primaquine, Proguanil, Promethazine, Propafenone, Propranolol, Quinidine, Quinine, Rabeprazole, Ranitidine, Ranolazine, Reboxetine, Rhein, Rilpivirine, Risperidone, Ritanserin, Ritonavir, Rolapitant, Rosiglitazone, Rotigotine, Rucaparib, Safinamide, Saquinavir, Selegiline, Sertraline, Sorafenib, Sparteine, St. John's Wort, Stiripentol, Sulconazole, Sulfanilamide, Sulfaphenazole, Tamoxifen, Tegaserod, Temsirolimus, Terbinafine, Terfenadine, Thioridazine, Thiothixene, Ticlopidine, Tipranavir, Tirbanibulin, Tranylcypromine, Trazodone, Triclabendazole, Tripelennamine, Trospium, Ubrogepant, Vemurafenib, Venlafaxine, Verapamil, Vernakalant, Vinblastine, Vinorelbine, Zafirlukast
3	Cytochrome P450 2D6 inducers	Modafinil, Oritavancin

	Interacting Group	Interacting Drugs
	Clotrimazole is a Cytochrome P450 2C8 inhibitor
1	Cytochrome P450 2C8 substrates	(R)-warfarin, (S)-Warfarin, Almotriptan, Aminophenazone, Amiodarone, Amitriptyline, Amodiaquine, Anastrozole, Antipyrine, Apalutamide, Apixaban, Apomorphine, Atorvastatin, Azelastine, Balaglitazone, Benzyl alcohol, Beraprost, Bioallethrin, Brigatinib, Buprenorphine, Cabazitaxel, Caffeine, Capravirine, Carbamazepine, Celecoxib, Cerivastatin, Chloroquine, Ciglitazone, Cisapride, Clozapine, Cyclophosphamide, Dabrafenib, Dapsone, Dasabuvir, Dexibuprofen, Diazepam, Diclofenac, Diethylstilbestrol, Diltiazem, Domperidone, Elagolix, Eltrombopag, Enasidenib, Enzalutamide, Erlotinib, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Eszopiclone, Ethinylestradiol, Febuxostat, Fluorouracil, Fluvastatin, Glasdegib, Halofantrine, Hydroxychloroquine, Ibuprofen, Ifosfamide, Imatinib, Irbesartan, Istradefylline, Ixazomib, Ketamine, Ketobemidone, Ketorolac, Lansoprazole, Lapatinib, Levomilnacipran, Licofelone, Lidocaine, Lobeglitazone, Lonafarnib, Loperamide, Loratadine, Lorlatinib, Lovastatin, Meloxicam, Mephenytoin, Mestranol, Methadone, Montelukast, Morphine, Muraglitazar, Mycophenolate mofetil, Naproxen, Netoglitazone, Nicardipine, Nicotine, Odanacatib, Olodaterol, Ombitasvir, Omeprazole, Ozanimod, Paclitaxel, Paramethadione, Pazopanib, Perospirone, Perphenazine, Phenprocoumon, Phenytoin, Pioglitazone, Piroxicam, Pitavastatin, Ponatinib, Propofol, Quinine, Relugolix, Remdesivir, Repaglinide, Riociguat, Rivoglitazone, Rosiglitazone, Selegiline, Selexipag, Selumetinib, Seratrodast, Simvastatin, Sitagliptin, Sorafenib, Sulfadiazine, Tazarotene, Tegafur, Tepotinib, Terbinafine, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Tirbanibulin, Tolbutamide, Torasemide, Tretinoin, Trifarotene, Trimethadione, Trimethoprim, Troglitazone, Tucatinib, Velpatasvir, Verapamil, Vortioxetine, Voxilaprevir, Warfarin, Zopiclone
2	Cytochrome P450 2C8 inducers	Avatrombopag, Betamethasone, Budesonide, Carbamazepine, Cenobamate, Cyclophosphamide, Dabrafenib, Dexamethasone, Dexamethasone acetate, Hydrocortisone, Hydrocortisone aceponate, Hydrocortisone acetate, Hydrocortisone butyrate, Hydrocortisone cypionate, Hydrocortisone phosphate, Hydrocortisone probutate, Hydrocortisone succinate, Hydrocortisone valerate, Ifosfamide, Isavuconazole, Ivosidenib, Lumacaftor, Methylprednisolone, Midostaurin, Nilotinib, Phenobarbital, Phenytoin, Pralsetinib, Prednisolone phosphate, Prednisone, Probenecid, Rifabutin, Rifampicin, Rifamycin, Rifapentine, Rifaximin, Ritonavir, Secobarbital
3	Cytochrome P450 2C8 inhibitors	Abemaciclib, Abiraterone, Alpelisib, Amitriptyline, Amlodipine, Amoxicillin, Anastrozole, Atazanavir, Atorvastatin, Balaglitazone, Belinostat, Bexarotene, Bezafibrate, Bosutinib, Cabozantinib, Candesartan, Candesartan cilexetil, Cerivastatin, Cholecalciferol, Ciglitazone, Cimetidine, Clascoterone, Clofazimine, Clopidogrel, Colchicine, Crisaborole, Dabrafenib, Deferasirox, Diethylstilbestrol, Efavirenz, Elexacaftor, Eltrombopag, Enasidenib, Enzalutamide, Erlotinib, Ethinylestradiol, Ezetimibe, Favipiravir, Felodipine, Fenofibrate, Fluticasone, Fluticasone furoate, Fluticasone propionate, Fluvastatin, Gemfibrozil, Genistein, Idelalisib, Irbesartan, Isavuconazole, Isoniazid, Ketoconazole, Ketoprofen, Lapatinib, Lenvatinib, Letermovir, Levothyroxine, Licofelone, Liotrix, Lobeglitazone, Lonafarnib, Loratadine, Losartan, Lumacaftor, Lumasiran, Medroxyprogesterone acetate, Mefenamic acid, Menadione, Methylene blue, Metronidazole, Miconazole, Midostaurin, Mifepristone, Mometasone, Mometasone furoate, Montelukast, Nabilone, Netoglitazone, Nicardipine, Nifedipine, Nilotinib, Nilvadipine, Opicapone, Oxybutynin, Pazopanib, Phenelzine, Pioglitazone, Pralsetinib, Pyrimethamine, Quercetin, Quinidine, Quinine, Rabeprazole, Raloxifene, Regorafenib, Rifamycin, Rilpivirine, Ripretinib, Ritonavir, Rivoglitazone, Rofecoxib, Rosiglitazone, Rucaparib, Salmeterol, Saquinavir, Selpercatinib, Simvastatin, Sorafenib, Spironolactone, Sulfaphenazole, Sulfinpyrazone, Tamoxifen, Tegaserod, Terfenadine, Teriflunomide, Ticlopidine, Tirbanibulin, Tolbutamide, Topiroxostat, Trametinib, Triazolam, Triclabendazole, Trimethoprim, Troglitazone, Troleandomycin, Ubrogepant, Vemurafenib, Verapamil, Vismodegib, Warfarin, Zafirlukast

	Interacting Group	Interacting Drugs
	Clotrimazole is a Cytochrome P450 3A4 substrate
1	Cytochrome P450 3A4 substrates	(R)-warfarin, (S)-Warfarin, 1,2-Benzodiazepine, 3,5-diiodothyropropionic acid, 5-androstenedione, 6-O-benzylguanine, 9-aminocamptothecin, Abemaciclib, Abiraterone, Acalabrutinib, Acenocoumarol, Acetaminophen, Adinazolam, Agmatine, Albendazole, Alclometasone, Aldosterone, Alfentanil, Alfuzosin, Aliskiren, Almotriptan, Alogliptin, Alosetron, Alpelisib, alpha-Tocopherol acetate, Alprazolam, Ambrisentan, Ambroxol, Amcinonide, Aminophenazone, Aminophylline, Amiodarone, Amitriptyline, Amlodipine, Amprenavir, Anastrozole, Androstenedione, Antipyrine, Apalutamide, Apixaban, Apremilast, Aprepitant, Aranidipine, Argatroban, Aripiprazole, Aripiprazole lauroxil, Artemether, Asenapine, Astemizole, Asunaprevir, Atazanavir, Atorvastatin, Atovaquone, Avanafil, Avapritinib, Axitinib, Azelastine, Azelnidipine, Azimilide, Azithromycin, Balaglitazone, Baloxavir marboxil, Banoxantrone, Baricitinib, Barnidipine, Beclomethasone dipropionate, Bedaquiline, Belinostat, Bencyclane, Benidipine, Benzphetamine, Bepridil, Betamethasone, Betamethasone phosphate, Bexarotene, Bezafibrate, Bicalutamide, Bictegravir, Bimatoprost, Bioallethrin, Bisoprolol, Blonanserin, Boceprevir, Bortezomib, Bosentan, Bosutinib, Brentuximab vedotin, Brexpiprazole, Brigatinib, Brinzolamide, Brivaracetam, Bromocriptine, Brotizolam, Budesonide, Bupivacaine, Buprenorphine, Buspirone, Busulfan, Butyrfentanyl, Cabazitaxel, Cabergoline, Cabozantinib, Caffeine, Calanolide A, Calcitriol, Canagliflozin, Cannabidiol, Capmatinib, Capravirine, Carbamazepine, Carboxyamidotriazole, Cariprazine, Caroverine, Carvedilol, Celecoxib, Cenobamate, Ceritinib, Cerivastatin, Cethromycin, Cevimeline, Chenodeoxycholic acid, Chlordiazepoxide, Chlormadinone, Chloroquine, Chlorpheniramine, Chlorzoxazone, Cholecalciferol, Ciclesonide, Ciglitazone, Cilnidipine, Cilostazol, Cinacalcet, Cinnarizine, Cisapride, Citalopram, Clarithromycin, Clevidipine, Clindamycin, Clobazam, Clobetasol, Clobetasol propionate, Clobetasone, Clofibrate, Clomethiazole, Clomipramine, Clonazepam, Clonidine, Clopidogrel, Clorazepic acid, Clotiazepam, Clozapine, Cobicistat, Cobimetinib, Cocaine, Codeine, Colchicine, Conivaptan, Conjugated estrogens, Copanlisib, Corticosterone, Corticotropin, Cortisone acetate, Crizotinib, Cyclandelate, Cyclobenzaprine, Cyclophosphamide, Cyclosporine, Cyproterone acetate, Cytarabine, Dabrafenib, Daclatasvir, Dacomitinib, Dapagliflozin, Dapoxetine, Dapsone, Darifenacin, Darodipine, Darolutamide, Darunavir, Dasabuvir, Dasatinib, Daunorubicin, Deflazacort, Delamanid, Delavirdine, Demegestone, Desogestrel, Desonide, Desoxycorticosterone acetate, Desoxycorticosterone pivalate, Desvenlafaxine, Deutetrabenazine, Dexamethasone, Dexamethasone acetate, Dexamethasone isonicotinate, Dexchlorpheniramine maleate, Dexlansoprazole, Dexloxiglumide, Dexniguldipine, Dextromethorphan, Dextropropoxyphene, Dexverapamil, Diazepam, Diclofenac, Dienogest, Diethylstilbestrol, Difluocortolone, Difluprednate, Digitoxin, Dihydro-alpha-ergocryptine, Dihydrocodeine, Dihydroergocornine, Dihydroergocristine, Dihydroergocryptine, Dihydroergotamine, Diltiazem, Diphenadione, Disopyramide, Disulfiram, Docetaxel, Dofetilide, Dolasetron, Domperidone, Donepezil, Doravirine, Dotarizine, Doxazosin, Doxepin, Doxorubicin, Doxycycline, Dronabinol, Dronedarone, Drospirenone, Duvelisib, Dydrogesterone, Ebastine, Efavirenz, Efonidipine, Elbasvir, Eletriptan, Elexacaftor, Eliglustat, Elvitegravir, Emopamil, Enasidenib, Encorafenib, Enfortumab vedotin, Entrectinib, Enzalutamide, Eperisone, Epinastine, Eplerenone, Equilenin, Equilin, Eravacycline, Erdafitinib, Ergoloid mesylate, Ergometrine, Ergotamine, Erlotinib, Erythromycin, Escitalopram, Esketamine, Esomeprazole, Estazolam, Esterified estrogens, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estramustine, Estrone, Estrone sulfate, Eszopiclone, Ethanol, Ethinylestradiol, Ethosuximide, Ethyl biscoumacetate, Ethylmorphine, Ethynodiol diacetate, Etizolam, Etonogestrel, Etoposide, Etoricoxib, Etravirine, Etynodiol, Everolimus, Exemestane, Fedratinib, Felbamate, Felodipine, Fendiline, Fenfluramine, Fentanyl, Fesoterodine, Finasteride, Fish oil, Flibanserin, Flucloxacillin, Fludrocortisone, Flumethasone, Flunarizine, Flunisolide, Flunitrazepam, Fluocinolone acetonide, Fluocinonide, Fluocortolone, Fluorometholone, Fluoxetine, Fluprednidene, Fluprednisolone, Fluprednisolone acetate, Flurandrenolide, Flurazepam, Fluspirilene, Flutamide, Fluticasone, Fluticasone furoate, Fluticasone propionate, Fluvastatin, Fluvoxamine, Fosamprenavir, Fosaprepitant, Fosnetupitant, Fosphenytoin, Fostamatinib, Fostemsavir, Fulvestrant, Fusidic acid, Galantamine, Gallopamil, Gefitinib, Gemfibrozil, Gestodene, Gestrinone, Gilteritinib, Glasdegib, Glyburide, Granisetron, Grazoprevir, Grepafloxacin, Guanfacine, Halcinonide, Halofantrine, Haloperidol, Halothane, HE3286, Hydrocodone, Hydrocortisone, Hydrocortisone aceponate, Hydrocortisone acetate, Hydrocortisone butyrate, Hydrocortisone cypionate, Hydrocortisone phosphate, Hydrocortisone probutate, Hydrocortisone succinate, Hydrocortisone valerate, Hydroxychloroquine, Hydroxyprogesterone, Hydroxyprogesterone caproate, Hydroxyzine, Ibrutinib, Ibuprofen, Icotinib, Idelalisib, Ifosfamide, Iloperidone, Imatinib, Imidafenacin, Imipramine, Imiquimod, Indacaterol, Indalpine, Indapamide, Indinavir, Ipecac, Irinotecan, Isavuconazole, Isavuconazonium, Isotretinoin, Isradipine, Istradefylline, Itraconazole, Ivabradine, Ivacaftor, Ivermectin, Ivosidenib, Ixabepilone, Ixazomib, Ketamine, Ketazolam, Ketobemidone, Ketoconazole, Lacidipine, Lacosamide, Lansoprazole, Lapatinib, Laquinimod, Larotrectinib, Lefamulin, Lemborexant, Lenvatinib, Lercanidipine, Letrozole, Levacetylmethadol, Levamlodipine, Levobupivacaine, Levocetirizine, Levomenthol, Levomilnacipran, Levonorgestrel, Lidocaine, Lidoflazine, Linagliptin, Liotrix, Lisuride, Lobeglitazone, Lomerizine, Lomitapide, Lonafarnib, Loperamide, Lopinavir, Loratadine, Lorazepam, Lorcaserin, Lorpiprazole, Losartan, Loteprednol etabonate, Lovastatin, Lumefantrine, Lurasidone, Lurbinectedin, Lynestrenol, Lysergic acid diethylamide, Macimorelin, Macitentan, Manidipine, Maraviroc, Medrogestone, Medroxyprogesterone acetate, Medrysone, Mefloquine, Megestrol acetate, Melengestrol, Meloxicam, Meperidine, Meprednisone, Mestranol, Methadone, Methaqualone, Methotrexate, Methoxyflurane, Methylergometrine, Methylprednisolone, Methylprednisone, Methyltestosterone, Methysergide, Metoclopramide, Metoprolol, Mexazolam, Mexiletine, Mianserin, Mibefradil, Midazolam, Midecamycin, Midostaurin, Mifepristone, Milnacipran, Mirabegron, Mirtazapine, Modafinil, Mometasone, Mometasone furoate, Montelukast, Morphine, Mycophenolate mofetil, Nabiximols, Naftopidil, Naloxegol, Nateglinide, Nebivolol, Nefazodone, Nelfinavir, Neratinib, Netoglitazone, Netupitant, Nevirapine, Nicardipine, Nicotine, Nifedipine, Niguldipine, Nilotinib, Niludipine, Nilvadipine, Nimesulide, Nimodipine, Nintedanib, Nisoldipine, Nitrazepam, Nitrendipine, Nomegestrol, Nomegestrol acetate, Norelgestromin, Norethindrone enanthate, Norethisterone, Norethynodrel, Norgestimate, Norgestrel, Nortriptyline, Nylidrin, Odanacatib, Olaparib, Oliceridine, Olopatadine, Omeprazole, Ondansetron, Opium, Orphenadrine, Osilodrostat, Osimertinib, Ospemifene, Otilonium, Oxybutynin, Oxycodone, Oxymorphone, Ozanimod, Paclitaxel, Palbociclib, Paliperidone, Palonosetron, Panobinostat, Pantoprazole, Paramethadione, Paramethasone, Parecoxib, Paricalcitol, Paritaprevir, Paroxetine, Pazopanib, Pemigatinib, Penfluridol, Perampanel, Perhexiline, Perospirone, Perphenazine, Pexidartinib, Phenacetin, Phenprocoumon, Phentermine, Phenytoin, Pimecrolimus, Pimozide, Pinacidil, Pinaverium, Pioglitazone, Piperaquine, Pipotiazine, Pitolisant, Plitidepsin, Polatuzumab vedotin, Pomalidomide, Ponatinib, Posaconazole, Pralsetinib, Pranlukast, Prasugrel, Prazepam, Praziquantel, Prednicarbate, Prednisolone, Prednisolone acetate, Prednisolone phosphate, Prednisone, Prednylidene, Pregnenolone, Prenylamine, Pretomanid, Primaquine, Progesterone, Promazine, Promegestone, Propacetamol, Propafenone, Propiverine, Propranolol, Prucalopride, Quazepam, Quetiapine, Quinacrine, Quingestanol, Quinidine, Quinine, Rabeprazole, Ramelteon, Ranolazine, Reboxetine, Regorafenib, Remdesivir, Repaglinide, Retapamulin, Ribociclib, Rifabutin, Rifalazil, Rifapentine, Rifaximin, Rilpivirine, Rimegepant, Rimexolone, Rimonabant, Riociguat, Ripretinib, Risdiplam, Risperidone, Ritonavir, Rivaroxaban, Rivoglitazone, Rofecoxib, Roflumilast, Rolapitant, Romidepsin, Ropivacaine, Rosiglitazone, Rotigotine, Roxithromycin, Rucaparib, Rufinamide, Rupatadine, Ruxolitinib, Safinamide, Salmeterol, Saquinavir, Saxagliptin, Scopolamine, Segesterone acetate, Selegiline, Seletracetam, Selexipag, Selinexor, Selpercatinib, Selumetinib, Seratrodast, Sertindole, Sertraline, Sevoflurane, Sibutramine, Sildenafil, Silodosin, Simeprevir, Simvastatin, Siponimod, Sirolimus, Sitagliptin, SN-38, Solifenacin, Sonidegib, Sorafenib, St. John's Wort, Sufentanil, Sulfadiazine, Sulfamethoxazole, Sulfinpyrazone, Sunitinib, Suvorexant, Synthetic Conjugated Estrogens, A, Synthetic Conjugated Estrogens, B, Tacrolimus, Tadalafil, Tamoxifen, Tamsulosin, Tasimelteon, Tasosartan, Taurochenodeoxycholic acid, Tazemetostat, Telaprevir, Telithromycin, Temazepam, Temsirolimus, Tenapanor, Teniposide, Tenofovir, Tenofovir alafenamide, Tepotinib, Terbinafine, Terfenadine, Terguride, Terodiline, Tesmilifene, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone propionate, Testosterone undecanoate, Tetracycline, Tetrahydropalmatine, Tetrandrine, Tezacaftor, Theophylline, Thiamylal, Thiotepa, Tiagabine, Tianeptine, Ticagrelor, Tinidazole, Tiotropium, Tipranavir, Tirbanibulin, Tocofersolan, Tocopherol, Tofacitinib, Tolfenamic acid, Tolterodine, Tolvaptan, Toremifene, Trabectedin, Tramadol, Tranilast, Trastuzumab deruxtecan, Trastuzumab emtansine, Trazodone, Tretinoin, Triamcinolone, Triazolam, Triclabendazole, Trifarotene, Trimebutine, Trimethadione, Trimethoprim, Troleandomycin, Ubrogepant, Udenafil, Ulipristal, Umbralisib, Umifenovir, Upadacitinib, Valbenazine, Valdecoxib, Vandetanib, Vanoxerine, Vardenafil, Velpatasvir, Vemurafenib, Venetoclax, Venlafaxine, Verapamil, Vibegron, Vicriviroc, Vilanterol, Vilazodone, Vinblastine, Vincristine, Vindesine, Vinflunine, Vinorelbine, Vinpocetine, Vismodegib, Vitamin D, Vitamin E, Voclosporin, Vorapaxar, Voriconazole, Vortioxetine, Voxelotor, Voxilaprevir, Warfarin, WIN 55212-2, Yohimbine, Zafirlukast, Zaleplon, Zanubrutinib, Zidovudine, Zileuton, Ziprasidone, Zolpidem, Zomepirac, Zonisamide, Zopiclone, Zotepine, Zuclopenthixol
2	Cytochrome P450 3A4 inducers	Acetaminophen, Amcinonide, Aminoglutethimide, Amprenavir, Apalutamide, Aprepitant, Aprobarbital, Armodafinil, Artemether, Asunaprevir, Avasimibe, Azatadine, Barbital, Beclomethasone dipropionate, Betamethasone, Betamethasone phosphate, Bexarotene, Bosentan, Budesonide, Calcitriol, Carbamazepine, Cefradine, Cenobamate, Cerivastatin, Chlorphenesin, Chlorpromazine, Clevidipine, Clobazam, Clobetasol, Clobetasol propionate, Clocortolone acetate, Clofibrate, Cloprednol, Clozapine, Corticotropin, Cortisone, Cortisone acetate, Cortivazol, Cyclophosphamide, Dabrafenib, Deferasirox, Deflazacort, Delafloxacin, Desonide, Dexamethasone, Dexamethasone acetate, Dexamethasone isonicotinate, Dicloxacillin, Difluocortolone, Echinacea, Efavirenz, Enasidenib, Enzalutamide, Esketamine, Eslicarbazepine, Eslicarbazepine acetate, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Ethanol, Etoposide, Etravirine, Felbamate, Flucloxacillin, Flunisolide, Fluocinolone acetonide, Fluocinonide, Fluocortolone, Fluorometholone, Fluprednidene, Fluprednidene acetate, Fluticasone, Fluticasone furoate, Formestane, Fosaprepitant, Fosphenytoin, Genistein, Glycerol phenylbutyrate, Griseofulvin, Halometasone, Hydrocortamate, Hydrocortisone, Hydrocortisone aceponate, Hydrocortisone acetate, Hydrocortisone butyrate, Hydrocortisone probutate, Hydrocortisone succinate, Hydrocortisone valerate, Idelalisib, Ifosfamide, Isavuconazole, Isavuconazonium, Ivosidenib, Ketamine, Lansoprazole, Lenvatinib, Lesinurad, Lumacaftor, Medroxyprogesterone acetate, Medrysone, Melengestrol acetate, Meperidine, Meprednisone, Metamizole, Methadone, Methylprednisolone, Methylprednisolone hemisuccinate, Metyrapone, Midostaurin, Mifepristone, Mitotane, Modafinil, Mometasone, Mometasone furoate, Nafcillin, Nevirapine, Nifedipine, Norgestimate, Omeprazole, Oritavancin, Orlistat, Osimertinib, Oxcarbazepine, Oxiconazole, Paclitaxel, Paramethasone, Pegvisomant, Pentobarbital, Perampanel, Pexidartinib, Phenobarbital, Phenylbutazone, Phenytoin, Pioglitazone, Pitolisant, Pralsetinib, Prednisolone, Prednisolone acetate, Prednisolone hemisuccinate, Prednisolone phosphate, Prednisone, Prednisone acetate, Prednylidene, Primidone, Probenecid, Progesterone, Propacetamol, Quinine, Rifabutin, Rifampicin, Rifamycin, Rifapentine, Rifaximin, Rimexolone, Rofecoxib, Rufinamide, Sarilumab, Seratrodast, Siltuximab, St. John's Wort, Sulfinpyrazone, Tamoxifen, Terbinafine, Tesmilifene, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Thiamylal, Tocilizumab, Topiramate, Trametinib, Triamcinolone, Troglitazone, Vemurafenib, Vinblastine, Vitamin E, Warfarin
3	Cytochrome P450 3A4 inhibitors	6-Deoxyerythronolide B, Abametapir, Abemaciclib, Abiraterone, Acalabrutinib, Acetazolamide, Albuterol, Aldesleukin, Amiodarone, Amprenavir, Anastrozole, Aprepitant, Arsenic trioxide, Astemizole, Atazanavir, AVE9633, Azelastine, Azithromycin, Barnidipine, Benidipine, Berotralstat, Bicalutamide, Bifonazole, Black cohosh, Boceprevir, Bosutinib, Brefeldin A, Brentuximab vedotin, Bromocriptine, Bryostatin 1, Buprenorphine, Candicidin, Cannabidiol, Capsaicin, Carbomycin, Casimersen, Caspofungin, Cenobamate, Ceritinib, Cerivastatin, Cethromycin, Chloramphenicol, Chlorzoxazone, Cimetidine, Ciprofloxacin, Citalopram, Clarithromycin, Clascoterone, Clevidipine, Clindamycin, Clofazimine, Clozapine, Cobicistat, Colchicine, Coltuximab ravtansine, Conivaptan, Crizotinib, Curcumin, Curcumin sulfate, Cyclosporine, Cyproterone acetate, Dabrafenib, Dalfopristin, Danazol, Danoprevir, Dapoxetine, Darunavir, Dasatinib, Daunorubicin, Delavirdine, Desipramine, Desvenlafaxine, Dexamethasone, Dexamethasone acetate, Dexamethasone isonicotinate, Dextropropoxyphene, Diazepam, Diclofenac, Diethylstilbestrol, Dihydroergotamine, Diltiazem, Dimethyl sulfoxide, Dirithromycin, Ditiocarb, Docetaxel, Doramectin, Dovitinib, Doxorubicin, Doxycycline, Dronedarone, Duloxetine, Econazole, Edetate calcium disodium anhydrous, Edetate disodium anhydrous, Efavirenz, Efonidipine, Elexacaftor, Elvitegravir, Enasidenib, Epinephrine, Epofolate, Epothilone D, Eprinomectin, Ergotamine, Erlotinib, Erythromycin, Ethambutol, Ethanol, Etoposide, Etoricoxib, Ezetimibe, Fidaxomicin, Fluconazole, Fluoxetine, Flurithromycin, Fluticasone, Fluticasone furoate, Fluticasone propionate, Fluvastatin, Fluvoxamine, Fosamprenavir, Fosaprepitant, Fosnetupitant, Fostamatinib, Fusidic acid, Gefitinib, Ginkgo biloba, Glecaprevir, Glyburide, GPI-1485, Haloperidol, Hydralazine, Idelalisib, Ifosfamide, Imatinib, Indalpine, Indinavir, Indisulam, Irbesartan, Isavuconazole, Isavuconazonium, Isradipine, Itraconazole, Ivacaftor, Ketazolam, Ketoconazole, Kitasamycin, KOS-1584, Lanreotide, Lansoprazole, Lapatinib, Lenvatinib, Lercanidipine, Lestaurtinib, Letermovir, Levoketoconazole, Linagliptin, Lomustine, Lonafarnib, Loperamide, Lopinavir, Loratadine, Lorvotuzumab mertansine, Losartan, Lovastatin, Luliconazole, Manidipine, Medical Cannabis, Mefloquine, Menadione, Mequitazine, Methadone, Methimazole, Methylene blue, Methylergometrine, Metronidazole, Metyrapone, Mibefradil, Miconazole, Midazolam, Midecamycin, Midostaurin, Mifepristone, Milnacipran, Miocamycin, Mirtazapine, Mirvetuximab soravtansine, Mitemcinal, Mitoxantrone, Naloxone, Nefazodone, Nelfinavir, Netupitant, Niacin, Nicardipine, Nicotinamide, Nifedipine, Nilotinib, Nilvadipine, Nitric Oxide, Norfloxacin, Noscapine, Octreotide, Olanzapine, Olaparib, Oleandomycin, Omeprazole, Oritavancin, Orphenadrine, Osilodrostat, Osimertinib, Oxcarbazepine, Oxetacaine, Oxybutynin, Oxymetholone, Palbociclib, Paramethasone, Paroxetine, Pasireotide, Patupilone, Pazopanib, Peppermint oil, Pergolide, Pexidartinib, Phenelzine, Pilocarpine, Piperaquine, Piperine, Posaconazole, Pralsetinib, Primaquine, Quinidine, Quinine, Quinupristin, Rabeprazole, Raloxifene, Ranitidine, Ranolazine, Reboxetine, Regorafenib, Remacemide, Remdesivir, Resveratrol, Ribociclib, Ridaforolimus, Rifamycin, Rilpivirine, Rimegepant, Ritonavir, Rokitamycin, Roxithromycin, Rucaparib, Rutin, Sagopilone, Saquinavir, Saracatinib, Sarilumab, Selamectin, Seproxetine, Simeprevir, Sitaxentan, SN-38, Solithromycin, Somatostatin, Sorafenib, Stiripentol, Sulfanilamide, Sunitinib, Tamoxifen, Telaprevir, Telithromycin, Teniposide, Terfenadine, Tesmilifene, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Tetracycline, Ticagrelor, Tildipirosin, Tilmicosin, Tioconazole, Tipranavir, Tirbanibulin, Tofisopam, Topiroxostat, Toremifene, Tranylcypromine, Triclabendazole, Troleandomycin, Tylosin, Tylvalosin, Valproic acid, Vapreotide, Venetoclax, Verapamil, Vinblastine, Voclosporin, Voriconazole, WIN 55212-2, Zafirlukast, Zimelidine

	Interacting Group	Interacting Drugs
	Clotrimazole is a Cytochrome P450 3A4 inhibitor
1	Cytochrome P450 3A4 substrates	(R)-warfarin, (S)-Warfarin, 1,2-Benzodiazepine, 3,5-diiodothyropropionic acid, 5-androstenedione, 6-O-benzylguanine, 9-aminocamptothecin, Abemaciclib, Abiraterone, Acalabrutinib, Acenocoumarol, Acetaminophen, Adinazolam, Agmatine, Albendazole, Alclometasone, Aldosterone, Alfentanil, Alfuzosin, Aliskiren, Almotriptan, Alogliptin, Alosetron, Alpelisib, alpha-Tocopherol acetate, Alprazolam, Ambrisentan, Ambroxol, Amcinonide, Aminophenazone, Aminophylline, Amiodarone, Amitriptyline, Amlodipine, Amprenavir, Anastrozole, Androstenedione, Antipyrine, Apalutamide, Apixaban, Apremilast, Aprepitant, Aranidipine, Argatroban, Aripiprazole, Aripiprazole lauroxil, Artemether, Asenapine, Astemizole, Asunaprevir, Atazanavir, Atorvastatin, Atovaquone, Avanafil, Avapritinib, Axitinib, Azelastine, Azelnidipine, Azimilide, Azithromycin, Balaglitazone, Baloxavir marboxil, Banoxantrone, Baricitinib, Barnidipine, Beclomethasone dipropionate, Bedaquiline, Belinostat, Bencyclane, Benidipine, Benzphetamine, Bepridil, Betamethasone, Betamethasone phosphate, Bexarotene, Bezafibrate, Bicalutamide, Bictegravir, Bimatoprost, Bioallethrin, Bisoprolol, Blonanserin, Boceprevir, Bortezomib, Bosentan, Bosutinib, Brentuximab vedotin, Brexpiprazole, Brigatinib, Brinzolamide, Brivaracetam, Bromocriptine, Brotizolam, Budesonide, Bupivacaine, Buprenorphine, Buspirone, Busulfan, Butyrfentanyl, Cabazitaxel, Cabergoline, Cabozantinib, Caffeine, Calanolide A, Calcitriol, Canagliflozin, Cannabidiol, Capmatinib, Capravirine, Carbamazepine, Carboxyamidotriazole, Cariprazine, Caroverine, Carvedilol, Celecoxib, Cenobamate, Ceritinib, Cerivastatin, Cethromycin, Cevimeline, Chenodeoxycholic acid, Chlordiazepoxide, Chlormadinone, Chloroquine, Chlorpheniramine, Chlorzoxazone, Cholecalciferol, Ciclesonide, Ciglitazone, Cilnidipine, Cilostazol, Cinacalcet, Cinnarizine, Cisapride, Citalopram, Clarithromycin, Clevidipine, Clindamycin, Clobazam, Clobetasol, Clobetasol propionate, Clobetasone, Clofibrate, Clomethiazole, Clomipramine, Clonazepam, Clonidine, Clopidogrel, Clorazepic acid, Clotiazepam, Clozapine, Cobicistat, Cobimetinib, Cocaine, Codeine, Colchicine, Conivaptan, Conjugated estrogens, Copanlisib, Corticosterone, Corticotropin, Cortisone acetate, Crizotinib, Cyclandelate, Cyclobenzaprine, Cyclophosphamide, Cyclosporine, Cyproterone acetate, Cytarabine, Dabrafenib, Daclatasvir, Dacomitinib, Dapagliflozin, Dapoxetine, Dapsone, Darifenacin, Darodipine, Darolutamide, Darunavir, Dasabuvir, Dasatinib, Daunorubicin, Deflazacort, Delamanid, Delavirdine, Demegestone, Desogestrel, Desonide, Desoxycorticosterone acetate, Desoxycorticosterone pivalate, Desvenlafaxine, Deutetrabenazine, Dexamethasone, Dexamethasone acetate, Dexamethasone isonicotinate, Dexchlorpheniramine maleate, Dexlansoprazole, Dexloxiglumide, Dexniguldipine, Dextromethorphan, Dextropropoxyphene, Dexverapamil, Diazepam, Diclofenac, Dienogest, Diethylstilbestrol, Difluocortolone, Difluprednate, Digitoxin, Dihydro-alpha-ergocryptine, Dihydrocodeine, Dihydroergocornine, Dihydroergocristine, Dihydroergocryptine, Dihydroergotamine, Diltiazem, Diphenadione, Disopyramide, Disulfiram, Docetaxel, Dofetilide, Dolasetron, Domperidone, Donepezil, Doravirine, Dotarizine, Doxazosin, Doxepin, Doxorubicin, Doxycycline, Dronabinol, Dronedarone, Drospirenone, Duvelisib, Dydrogesterone, Ebastine, Efavirenz, Efonidipine, Elbasvir, Eletriptan, Elexacaftor, Eliglustat, Elvitegravir, Emopamil, Enasidenib, Encorafenib, Enfortumab vedotin, Entrectinib, Enzalutamide, Eperisone, Epinastine, Eplerenone, Equilenin, Equilin, Eravacycline, Erdafitinib, Ergoloid mesylate, Ergometrine, Ergotamine, Erlotinib, Erythromycin, Escitalopram, Esketamine, Esomeprazole, Estazolam, Esterified estrogens, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estramustine, Estrone, Estrone sulfate, Eszopiclone, Ethanol, Ethinylestradiol, Ethosuximide, Ethyl biscoumacetate, Ethylmorphine, Ethynodiol diacetate, Etizolam, Etonogestrel, Etoposide, Etoricoxib, Etravirine, Etynodiol, Everolimus, Exemestane, Fedratinib, Felbamate, Felodipine, Fendiline, Fenfluramine, Fentanyl, Fesoterodine, Finasteride, Fish oil, Flibanserin, Flucloxacillin, Fludrocortisone, Flumethasone, Flunarizine, Flunisolide, Flunitrazepam, Fluocinolone acetonide, Fluocinonide, Fluocortolone, Fluorometholone, Fluoxetine, Fluprednidene, Fluprednisolone, Fluprednisolone acetate, Flurandrenolide, Flurazepam, Fluspirilene, Flutamide, Fluticasone, Fluticasone furoate, Fluticasone propionate, Fluvastatin, Fluvoxamine, Fosamprenavir, Fosaprepitant, Fosnetupitant, Fosphenytoin, Fostamatinib, Fostemsavir, Fulvestrant, Fusidic acid, Galantamine, Gallopamil, Gefitinib, Gemfibrozil, Gestodene, Gestrinone, Gilteritinib, Glasdegib, Glyburide, Granisetron, Grazoprevir, Grepafloxacin, Guanfacine, Halcinonide, Halofantrine, Haloperidol, Halothane, HE3286, Hydrocodone, Hydrocortisone, Hydrocortisone aceponate, Hydrocortisone acetate, Hydrocortisone butyrate, Hydrocortisone cypionate, Hydrocortisone phosphate, Hydrocortisone probutate, Hydrocortisone succinate, Hydrocortisone valerate, Hydroxychloroquine, Hydroxyprogesterone, Hydroxyprogesterone caproate, Hydroxyzine, Ibrutinib, Ibuprofen, Icotinib, Idelalisib, Ifosfamide, Iloperidone, Imatinib, Imidafenacin, Imipramine, Imiquimod, Indacaterol, Indalpine, Indapamide, Indinavir, Ipecac, Irinotecan, Isavuconazole, Isavuconazonium, Isotretinoin, Isradipine, Istradefylline, Itraconazole, Ivabradine, Ivacaftor, Ivermectin, Ivosidenib, Ixabepilone, Ixazomib, Ketamine, Ketazolam, Ketobemidone, Ketoconazole, Lacidipine, Lacosamide, Lansoprazole, Lapatinib, Laquinimod, Larotrectinib, Lefamulin, Lemborexant, Lenvatinib, Lercanidipine, Letrozole, Levacetylmethadol, Levamlodipine, Levobupivacaine, Levocetirizine, Levomenthol, Levomilnacipran, Levonorgestrel, Lidocaine, Lidoflazine, Linagliptin, Liotrix, Lisuride, Lobeglitazone, Lomerizine, Lomitapide, Lonafarnib, Loperamide, Lopinavir, Loratadine, Lorazepam, Lorcaserin, Lorpiprazole, Losartan, Loteprednol etabonate, Lovastatin, Lumefantrine, Lurasidone, Lurbinectedin, Lynestrenol, Lysergic acid diethylamide, Macimorelin, Macitentan, Manidipine, Maraviroc, Medrogestone, Medroxyprogesterone acetate, Medrysone, Mefloquine, Megestrol acetate, Melengestrol, Meloxicam, Meperidine, Meprednisone, Mestranol, Methadone, Methaqualone, Methotrexate, Methoxyflurane, Methylergometrine, Methylprednisolone, Methylprednisone, Methyltestosterone, Methysergide, Metoclopramide, Metoprolol, Mexazolam, Mexiletine, Mianserin, Mibefradil, Midazolam, Midecamycin, Midostaurin, Mifepristone, Milnacipran, Mirabegron, Mirtazapine, Modafinil, Mometasone, Mometasone furoate, Montelukast, Morphine, Mycophenolate mofetil, Nabiximols, Naftopidil, Naloxegol, Nateglinide, Nebivolol, Nefazodone, Nelfinavir, Neratinib, Netoglitazone, Netupitant, Nevirapine, Nicardipine, Nicotine, Nifedipine, Niguldipine, Nilotinib, Niludipine, Nilvadipine, Nimesulide, Nimodipine, Nintedanib, Nisoldipine, Nitrazepam, Nitrendipine, Nomegestrol, Nomegestrol acetate, Norelgestromin, Norethindrone enanthate, Norethisterone, Norethynodrel, Norgestimate, Norgestrel, Nortriptyline, Nylidrin, Odanacatib, Olaparib, Oliceridine, Olopatadine, Omeprazole, Ondansetron, Opium, Orphenadrine, Osilodrostat, Osimertinib, Ospemifene, Otilonium, Oxybutynin, Oxycodone, Oxymorphone, Ozanimod, Paclitaxel, Palbociclib, Paliperidone, Palonosetron, Panobinostat, Pantoprazole, Paramethadione, Paramethasone, Parecoxib, Paricalcitol, Paritaprevir, Paroxetine, Pazopanib, Pemigatinib, Penfluridol, Perampanel, Perhexiline, Perospirone, Perphenazine, Pexidartinib, Phenacetin, Phenprocoumon, Phentermine, Phenytoin, Pimecrolimus, Pimozide, Pinacidil, Pinaverium, Pioglitazone, Piperaquine, Pipotiazine, Pitolisant, Plitidepsin, Polatuzumab vedotin, Pomalidomide, Ponatinib, Posaconazole, Pralsetinib, Pranlukast, Prasugrel, Prazepam, Praziquantel, Prednicarbate, Prednisolone, Prednisolone acetate, Prednisolone phosphate, Prednisone, Prednylidene, Pregnenolone, Prenylamine, Pretomanid, Primaquine, Progesterone, Promazine, Promegestone, Propacetamol, Propafenone, Propiverine, Propranolol, Prucalopride, Quazepam, Quetiapine, Quinacrine, Quingestanol, Quinidine, Quinine, Rabeprazole, Ramelteon, Ranolazine, Reboxetine, Regorafenib, Remdesivir, Repaglinide, Retapamulin, Ribociclib, Rifabutin, Rifalazil, Rifapentine, Rifaximin, Rilpivirine, Rimegepant, Rimexolone, Rimonabant, Riociguat, Ripretinib, Risdiplam, Risperidone, Ritonavir, Rivaroxaban, Rivoglitazone, Rofecoxib, Roflumilast, Rolapitant, Romidepsin, Ropivacaine, Rosiglitazone, Rotigotine, Roxithromycin, Rucaparib, Rufinamide, Rupatadine, Ruxolitinib, Safinamide, Salmeterol, Saquinavir, Saxagliptin, Scopolamine, Segesterone acetate, Selegiline, Seletracetam, Selexipag, Selinexor, Selpercatinib, Selumetinib, Seratrodast, Sertindole, Sertraline, Sevoflurane, Sibutramine, Sildenafil, Silodosin, Simeprevir, Simvastatin, Siponimod, Sirolimus, Sitagliptin, SN-38, Solifenacin, Sonidegib, Sorafenib, St. John's Wort, Sufentanil, Sulfadiazine, Sulfamethoxazole, Sulfinpyrazone, Sunitinib, Suvorexant, Synthetic Conjugated Estrogens, A, Synthetic Conjugated Estrogens, B, Tacrolimus, Tadalafil, Tamoxifen, Tamsulosin, Tasimelteon, Tasosartan, Taurochenodeoxycholic acid, Tazemetostat, Telaprevir, Telithromycin, Temazepam, Temsirolimus, Tenapanor, Teniposide, Tenofovir, Tenofovir alafenamide, Tepotinib, Terbinafine, Terfenadine, Terguride, Terodiline, Tesmilifene, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone propionate, Testosterone undecanoate, Tetracycline, Tetrahydropalmatine, Tetrandrine, Tezacaftor, Theophylline, Thiamylal, Thiotepa, Tiagabine, Tianeptine, Ticagrelor, Tinidazole, Tiotropium, Tipranavir, Tirbanibulin, Tocofersolan, Tocopherol, Tofacitinib, Tolfenamic acid, Tolterodine, Tolvaptan, Toremifene, Trabectedin, Tramadol, Tranilast, Trastuzumab deruxtecan, Trastuzumab emtansine, Trazodone, Tretinoin, Triamcinolone, Triazolam, Triclabendazole, Trifarotene, Trimebutine, Trimethadione, Trimethoprim, Troleandomycin, Ubrogepant, Udenafil, Ulipristal, Umbralisib, Umifenovir, Upadacitinib, Valbenazine, Valdecoxib, Vandetanib, Vanoxerine, Vardenafil, Velpatasvir, Vemurafenib, Venetoclax, Venlafaxine, Verapamil, Vibegron, Vicriviroc, Vilanterol, Vilazodone, Vinblastine, Vincristine, Vindesine, Vinflunine, Vinorelbine, Vinpocetine, Vismodegib, Vitamin D, Vitamin E, Voclosporin, Vorapaxar, Voriconazole, Vortioxetine, Voxelotor, Voxilaprevir, Warfarin, WIN 55212-2, Yohimbine, Zafirlukast, Zaleplon, Zanubrutinib, Zidovudine, Zileuton, Ziprasidone, Zolpidem, Zomepirac, Zonisamide, Zopiclone, Zotepine, Zuclopenthixol
2	Cytochrome P450 3A4 inducers	Acetaminophen, Amcinonide, Aminoglutethimide, Amprenavir, Apalutamide, Aprepitant, Aprobarbital, Armodafinil, Artemether, Asunaprevir, Avasimibe, Azatadine, Barbital, Beclomethasone dipropionate, Betamethasone, Betamethasone phosphate, Bexarotene, Bosentan, Budesonide, Calcitriol, Carbamazepine, Cefradine, Cenobamate, Cerivastatin, Chlorphenesin, Chlorpromazine, Clevidipine, Clobazam, Clobetasol, Clobetasol propionate, Clocortolone acetate, Clofibrate, Cloprednol, Clozapine, Corticotropin, Cortisone, Cortisone acetate, Cortivazol, Cyclophosphamide, Dabrafenib, Deferasirox, Deflazacort, Delafloxacin, Desonide, Dexamethasone, Dexamethasone acetate, Dexamethasone isonicotinate, Dicloxacillin, Difluocortolone, Echinacea, Efavirenz, Enasidenib, Enzalutamide, Esketamine, Eslicarbazepine, Eslicarbazepine acetate, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Ethanol, Etoposide, Etravirine, Felbamate, Flucloxacillin, Flunisolide, Fluocinolone acetonide, Fluocinonide, Fluocortolone, Fluorometholone, Fluprednidene, Fluprednidene acetate, Fluticasone, Fluticasone furoate, Formestane, Fosaprepitant, Fosphenytoin, Genistein, Glycerol phenylbutyrate, Griseofulvin, Halometasone, Hydrocortamate, Hydrocortisone, Hydrocortisone aceponate, Hydrocortisone acetate, Hydrocortisone butyrate, Hydrocortisone probutate, Hydrocortisone succinate, Hydrocortisone valerate, Idelalisib, Ifosfamide, Isavuconazole, Isavuconazonium, Ivosidenib, Ketamine, Lansoprazole, Lenvatinib, Lesinurad, Lumacaftor, Medroxyprogesterone acetate, Medrysone, Melengestrol acetate, Meperidine, Meprednisone, Metamizole, Methadone, Methylprednisolone, Methylprednisolone hemisuccinate, Metyrapone, Midostaurin, Mifepristone, Mitotane, Modafinil, Mometasone, Mometasone furoate, Nafcillin, Nevirapine, Nifedipine, Norgestimate, Omeprazole, Oritavancin, Orlistat, Osimertinib, Oxcarbazepine, Oxiconazole, Paclitaxel, Paramethasone, Pegvisomant, Pentobarbital, Perampanel, Pexidartinib, Phenobarbital, Phenylbutazone, Phenytoin, Pioglitazone, Pitolisant, Pralsetinib, Prednisolone, Prednisolone acetate, Prednisolone hemisuccinate, Prednisolone phosphate, Prednisone, Prednisone acetate, Prednylidene, Primidone, Probenecid, Progesterone, Propacetamol, Quinine, Rifabutin, Rifampicin, Rifamycin, Rifapentine, Rifaximin, Rimexolone, Rofecoxib, Rufinamide, Sarilumab, Seratrodast, Siltuximab, St. John's Wort, Sulfinpyrazone, Tamoxifen, Terbinafine, Tesmilifene, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Thiamylal, Tocilizumab, Topiramate, Trametinib, Triamcinolone, Troglitazone, Vemurafenib, Vinblastine, Vitamin E, Warfarin
3	Cytochrome P450 3A4 inhibitors	6-Deoxyerythronolide B, Abametapir, Abemaciclib, Abiraterone, Acalabrutinib, Acetazolamide, Albuterol, Aldesleukin, Amiodarone, Amprenavir, Anastrozole, Aprepitant, Arsenic trioxide, Astemizole, Atazanavir, AVE9633, Azelastine, Azithromycin, Barnidipine, Benidipine, Berotralstat, Bicalutamide, Bifonazole, Black cohosh, Boceprevir, Bosutinib, Brefeldin A, Brentuximab vedotin, Bromocriptine, Bryostatin 1, Buprenorphine, Candicidin, Cannabidiol, Capsaicin, Carbomycin, Casimersen, Caspofungin, Cenobamate, Ceritinib, Cerivastatin, Cethromycin, Chloramphenicol, Chlorzoxazone, Cimetidine, Ciprofloxacin, Citalopram, Clarithromycin, Clascoterone, Clevidipine, Clindamycin, Clofazimine, Clozapine, Cobicistat, Colchicine, Coltuximab ravtansine, Conivaptan, Crizotinib, Curcumin, Curcumin sulfate, Cyclosporine, Cyproterone acetate, Dabrafenib, Dalfopristin, Danazol, Danoprevir, Dapoxetine, Darunavir, Dasatinib, Daunorubicin, Delavirdine, Desipramine, Desvenlafaxine, Dexamethasone, Dexamethasone acetate, Dexamethasone isonicotinate, Dextropropoxyphene, Diazepam, Diclofenac, Diethylstilbestrol, Dihydroergotamine, Diltiazem, Dimethyl sulfoxide, Dirithromycin, Ditiocarb, Docetaxel, Doramectin, Dovitinib, Doxorubicin, Doxycycline, Dronedarone, Duloxetine, Econazole, Edetate calcium disodium anhydrous, Edetate disodium anhydrous, Efavirenz, Efonidipine, Elexacaftor, Elvitegravir, Enasidenib, Epinephrine, Epofolate, Epothilone D, Eprinomectin, Ergotamine, Erlotinib, Erythromycin, Ethambutol, Ethanol, Etoposide, Etoricoxib, Ezetimibe, Fidaxomicin, Fluconazole, Fluoxetine, Flurithromycin, Fluticasone, Fluticasone furoate, Fluticasone propionate, Fluvastatin, Fluvoxamine, Fosamprenavir, Fosaprepitant, Fosnetupitant, Fostamatinib, Fusidic acid, Gefitinib, Ginkgo biloba, Glecaprevir, Glyburide, GPI-1485, Haloperidol, Hydralazine, Idelalisib, Ifosfamide, Imatinib, Indalpine, Indinavir, Indisulam, Irbesartan, Isavuconazole, Isavuconazonium, Isradipine, Itraconazole, Ivacaftor, Ketazolam, Ketoconazole, Kitasamycin, KOS-1584, Lanreotide, Lansoprazole, Lapatinib, Lenvatinib, Lercanidipine, Lestaurtinib, Letermovir, Levoketoconazole, Linagliptin, Lomustine, Lonafarnib, Loperamide, Lopinavir, Loratadine, Lorvotuzumab mertansine, Losartan, Lovastatin, Luliconazole, Manidipine, Medical Cannabis, Mefloquine, Menadione, Mequitazine, Methadone, Methimazole, Methylene blue, Methylergometrine, Metronidazole, Metyrapone, Mibefradil, Miconazole, Midazolam, Midecamycin, Midostaurin, Mifepristone, Milnacipran, Miocamycin, Mirtazapine, Mirvetuximab soravtansine, Mitemcinal, Mitoxantrone, Naloxone, Nefazodone, Nelfinavir, Netupitant, Niacin, Nicardipine, Nicotinamide, Nifedipine, Nilotinib, Nilvadipine, Nitric Oxide, Norfloxacin, Noscapine, Octreotide, Olanzapine, Olaparib, Oleandomycin, Omeprazole, Oritavancin, Orphenadrine, Osilodrostat, Osimertinib, Oxcarbazepine, Oxetacaine, Oxybutynin, Oxymetholone, Palbociclib, Paramethasone, Paroxetine, Pasireotide, Patupilone, Pazopanib, Peppermint oil, Pergolide, Pexidartinib, Phenelzine, Pilocarpine, Piperaquine, Piperine, Posaconazole, Pralsetinib, Primaquine, Quinidine, Quinine, Quinupristin, Rabeprazole, Raloxifene, Ranitidine, Ranolazine, Reboxetine, Regorafenib, Remacemide, Remdesivir, Resveratrol, Ribociclib, Ridaforolimus, Rifamycin, Rilpivirine, Rimegepant, Ritonavir, Rokitamycin, Roxithromycin, Rucaparib, Rutin, Sagopilone, Saquinavir, Saracatinib, Sarilumab, Selamectin, Seproxetine, Simeprevir, Sitaxentan, SN-38, Solithromycin, Somatostatin, Sorafenib, Stiripentol, Sulfanilamide, Sunitinib, Tamoxifen, Telaprevir, Telithromycin, Teniposide, Terfenadine, Tesmilifene, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Tetracycline, Ticagrelor, Tildipirosin, Tilmicosin, Tioconazole, Tipranavir, Tirbanibulin, Tofisopam, Topiroxostat, Toremifene, Tranylcypromine, Triclabendazole, Troleandomycin, Tylosin, Tylvalosin, Valproic acid, Vapreotide, Venetoclax, Verapamil, Vinblastine, Voclosporin, Voriconazole, WIN 55212-2, Zafirlukast, Zimelidine

	Interacting Group	Interacting Drugs
	Clotrimazole is a Cytochrome P450 3A4 inducer
1	Cytochrome P450 3A4 substrates	(R)-warfarin, (S)-Warfarin, 1,2-Benzodiazepine, 3,5-diiodothyropropionic acid, 5-androstenedione, 6-O-benzylguanine, 9-aminocamptothecin, Abemaciclib, Abiraterone, Acalabrutinib, Acenocoumarol, Acetaminophen, Adinazolam, Agmatine, Albendazole, Alclometasone, Aldosterone, Alfentanil, Alfuzosin, Aliskiren, Almotriptan, Alogliptin, Alosetron, Alpelisib, alpha-Tocopherol acetate, Alprazolam, Ambrisentan, Ambroxol, Amcinonide, Aminophenazone, Aminophylline, Amiodarone, Amitriptyline, Amlodipine, Amprenavir, Anastrozole, Androstenedione, Antipyrine, Apalutamide, Apixaban, Apremilast, Aprepitant, Aranidipine, Argatroban, Aripiprazole, Aripiprazole lauroxil, Artemether, Asenapine, Astemizole, Asunaprevir, Atazanavir, Atorvastatin, Atovaquone, Avanafil, Avapritinib, Axitinib, Azelastine, Azelnidipine, Azimilide, Azithromycin, Balaglitazone, Baloxavir marboxil, Banoxantrone, Baricitinib, Barnidipine, Beclomethasone dipropionate, Bedaquiline, Belinostat, Bencyclane, Benidipine, Benzphetamine, Bepridil, Betamethasone, Betamethasone phosphate, Bexarotene, Bezafibrate, Bicalutamide, Bictegravir, Bimatoprost, Bioallethrin, Bisoprolol, Blonanserin, Boceprevir, Bortezomib, Bosentan, Bosutinib, Brentuximab vedotin, Brexpiprazole, Brigatinib, Brinzolamide, Brivaracetam, Bromocriptine, Brotizolam, Budesonide, Bupivacaine, Buprenorphine, Buspirone, Busulfan, Butyrfentanyl, Cabazitaxel, Cabergoline, Cabozantinib, Caffeine, Calanolide A, Calcitriol, Canagliflozin, Cannabidiol, Capmatinib, Capravirine, Carbamazepine, Carboxyamidotriazole, Cariprazine, Caroverine, Carvedilol, Celecoxib, Cenobamate, Ceritinib, Cerivastatin, Cethromycin, Cevimeline, Chenodeoxycholic acid, Chlordiazepoxide, Chlormadinone, Chloroquine, Chlorpheniramine, Chlorzoxazone, Cholecalciferol, Ciclesonide, Ciglitazone, Cilnidipine, Cilostazol, Cinacalcet, Cinnarizine, Cisapride, Citalopram, Clarithromycin, Clevidipine, Clindamycin, Clobazam, Clobetasol, Clobetasol propionate, Clobetasone, Clofibrate, Clomethiazole, Clomipramine, Clonazepam, Clonidine, Clopidogrel, Clorazepic acid, Clotiazepam, Clozapine, Cobicistat, Cobimetinib, Cocaine, Codeine, Colchicine, Conivaptan, Conjugated estrogens, Copanlisib, Corticosterone, Corticotropin, Cortisone acetate, Crizotinib, Cyclandelate, Cyclobenzaprine, Cyclophosphamide, Cyclosporine, Cyproterone acetate, Cytarabine, Dabrafenib, Daclatasvir, Dacomitinib, Dapagliflozin, Dapoxetine, Dapsone, Darifenacin, Darodipine, Darolutamide, Darunavir, Dasabuvir, Dasatinib, Daunorubicin, Deflazacort, Delamanid, Delavirdine, Demegestone, Desogestrel, Desonide, Desoxycorticosterone acetate, Desoxycorticosterone pivalate, Desvenlafaxine, Deutetrabenazine, Dexamethasone, Dexamethasone acetate, Dexamethasone isonicotinate, Dexchlorpheniramine maleate, Dexlansoprazole, Dexloxiglumide, Dexniguldipine, Dextromethorphan, Dextropropoxyphene, Dexverapamil, Diazepam, Diclofenac, Dienogest, Diethylstilbestrol, Difluocortolone, Difluprednate, Digitoxin, Dihydro-alpha-ergocryptine, Dihydrocodeine, Dihydroergocornine, Dihydroergocristine, Dihydroergocryptine, Dihydroergotamine, Diltiazem, Diphenadione, Disopyramide, Disulfiram, Docetaxel, Dofetilide, Dolasetron, Domperidone, Donepezil, Doravirine, Dotarizine, Doxazosin, Doxepin, Doxorubicin, Doxycycline, Dronabinol, Dronedarone, Drospirenone, Duvelisib, Dydrogesterone, Ebastine, Efavirenz, Efonidipine, Elbasvir, Eletriptan, Elexacaftor, Eliglustat, Elvitegravir, Emopamil, Enasidenib, Encorafenib, Enfortumab vedotin, Entrectinib, Enzalutamide, Eperisone, Epinastine, Eplerenone, Equilenin, Equilin, Eravacycline, Erdafitinib, Ergoloid mesylate, Ergometrine, Ergotamine, Erlotinib, Erythromycin, Escitalopram, Esketamine, Esomeprazole, Estazolam, Esterified estrogens, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estramustine, Estrone, Estrone sulfate, Eszopiclone, Ethanol, Ethinylestradiol, Ethosuximide, Ethyl biscoumacetate, Ethylmorphine, Ethynodiol diacetate, Etizolam, Etonogestrel, Etoposide, Etoricoxib, Etravirine, Etynodiol, Everolimus, Exemestane, Fedratinib, Felbamate, Felodipine, Fendiline, Fenfluramine, Fentanyl, Fesoterodine, Finasteride, Fish oil, Flibanserin, Flucloxacillin, Fludrocortisone, Flumethasone, Flunarizine, Flunisolide, Flunitrazepam, Fluocinolone acetonide, Fluocinonide, Fluocortolone, Fluorometholone, Fluoxetine, Fluprednidene, Fluprednisolone, Fluprednisolone acetate, Flurandrenolide, Flurazepam, Fluspirilene, Flutamide, Fluticasone, Fluticasone furoate, Fluticasone propionate, Fluvastatin, Fluvoxamine, Fosamprenavir, Fosaprepitant, Fosnetupitant, Fosphenytoin, Fostamatinib, Fostemsavir, Fulvestrant, Fusidic acid, Galantamine, Gallopamil, Gefitinib, Gemfibrozil, Gestodene, Gestrinone, Gilteritinib, Glasdegib, Glyburide, Granisetron, Grazoprevir, Grepafloxacin, Guanfacine, Halcinonide, Halofantrine, Haloperidol, Halothane, HE3286, Hydrocodone, Hydrocortisone, Hydrocortisone aceponate, Hydrocortisone acetate, Hydrocortisone butyrate, Hydrocortisone cypionate, Hydrocortisone phosphate, Hydrocortisone probutate, Hydrocortisone succinate, Hydrocortisone valerate, Hydroxychloroquine, Hydroxyprogesterone, Hydroxyprogesterone caproate, Hydroxyzine, Ibrutinib, Ibuprofen, Icotinib, Idelalisib, Ifosfamide, Iloperidone, Imatinib, Imidafenacin, Imipramine, Imiquimod, Indacaterol, Indalpine, Indapamide, Indinavir, Ipecac, Irinotecan, Isavuconazole, Isavuconazonium, Isotretinoin, Isradipine, Istradefylline, Itraconazole, Ivabradine, Ivacaftor, Ivermectin, Ivosidenib, Ixabepilone, Ixazomib, Ketamine, Ketazolam, Ketobemidone, Ketoconazole, Lacidipine, Lacosamide, Lansoprazole, Lapatinib, Laquinimod, Larotrectinib, Lefamulin, Lemborexant, Lenvatinib, Lercanidipine, Letrozole, Levacetylmethadol, Levamlodipine, Levobupivacaine, Levocetirizine, Levomenthol, Levomilnacipran, Levonorgestrel, Lidocaine, Lidoflazine, Linagliptin, Liotrix, Lisuride, Lobeglitazone, Lomerizine, Lomitapide, Lonafarnib, Loperamide, Lopinavir, Loratadine, Lorazepam, Lorcaserin, Lorpiprazole, Losartan, Loteprednol etabonate, Lovastatin, Lumefantrine, Lurasidone, Lurbinectedin, Lynestrenol, Lysergic acid diethylamide, Macimorelin, Macitentan, Manidipine, Maraviroc, Medrogestone, Medroxyprogesterone acetate, Medrysone, Mefloquine, Megestrol acetate, Melengestrol, Meloxicam, Meperidine, Meprednisone, Mestranol, Methadone, Methaqualone, Methotrexate, Methoxyflurane, Methylergometrine, Methylprednisolone, Methylprednisone, Methyltestosterone, Methysergide, Metoclopramide, Metoprolol, Mexazolam, Mexiletine, Mianserin, Mibefradil, Midazolam, Midecamycin, Midostaurin, Mifepristone, Milnacipran, Mirabegron, Mirtazapine, Modafinil, Mometasone, Mometasone furoate, Montelukast, Morphine, Mycophenolate mofetil, Nabiximols, Naftopidil, Naloxegol, Nateglinide, Nebivolol, Nefazodone, Nelfinavir, Neratinib, Netoglitazone, Netupitant, Nevirapine, Nicardipine, Nicotine, Nifedipine, Niguldipine, Nilotinib, Niludipine, Nilvadipine, Nimesulide, Nimodipine, Nintedanib, Nisoldipine, Nitrazepam, Nitrendipine, Nomegestrol, Nomegestrol acetate, Norelgestromin, Norethindrone enanthate, Norethisterone, Norethynodrel, Norgestimate, Norgestrel, Nortriptyline, Nylidrin, Odanacatib, Olaparib, Oliceridine, Olopatadine, Omeprazole, Ondansetron, Opium, Orphenadrine, Osilodrostat, Osimertinib, Ospemifene, Otilonium, Oxybutynin, Oxycodone, Oxymorphone, Ozanimod, Paclitaxel, Palbociclib, Paliperidone, Palonosetron, Panobinostat, Pantoprazole, Paramethadione, Paramethasone, Parecoxib, Paricalcitol, Paritaprevir, Paroxetine, Pazopanib, Pemigatinib, Penfluridol, Perampanel, Perhexiline, Perospirone, Perphenazine, Pexidartinib, Phenacetin, Phenprocoumon, Phentermine, Phenytoin, Pimecrolimus, Pimozide, Pinacidil, Pinaverium, Pioglitazone, Piperaquine, Pipotiazine, Pitolisant, Plitidepsin, Polatuzumab vedotin, Pomalidomide, Ponatinib, Posaconazole, Pralsetinib, Pranlukast, Prasugrel, Prazepam, Praziquantel, Prednicarbate, Prednisolone, Prednisolone acetate, Prednisolone phosphate, Prednisone, Prednylidene, Pregnenolone, Prenylamine, Pretomanid, Primaquine, Progesterone, Promazine, Promegestone, Propacetamol, Propafenone, Propiverine, Propranolol, Prucalopride, Quazepam, Quetiapine, Quinacrine, Quingestanol, Quinidine, Quinine, Rabeprazole, Ramelteon, Ranolazine, Reboxetine, Regorafenib, Remdesivir, Repaglinide, Retapamulin, Ribociclib, Rifabutin, Rifalazil, Rifapentine, Rifaximin, Rilpivirine, Rimegepant, Rimexolone, Rimonabant, Riociguat, Ripretinib, Risdiplam, Risperidone, Ritonavir, Rivaroxaban, Rivoglitazone, Rofecoxib, Roflumilast, Rolapitant, Romidepsin, Ropivacaine, Rosiglitazone, Rotigotine, Roxithromycin, Rucaparib, Rufinamide, Rupatadine, Ruxolitinib, Safinamide, Salmeterol, Saquinavir, Saxagliptin, Scopolamine, Segesterone acetate, Selegiline, Seletracetam, Selexipag, Selinexor, Selpercatinib, Selumetinib, Seratrodast, Sertindole, Sertraline, Sevoflurane, Sibutramine, Sildenafil, Silodosin, Simeprevir, Simvastatin, Siponimod, Sirolimus, Sitagliptin, SN-38, Solifenacin, Sonidegib, Sorafenib, St. John's Wort, Sufentanil, Sulfadiazine, Sulfamethoxazole, Sulfinpyrazone, Sunitinib, Suvorexant, Synthetic Conjugated Estrogens, A, Synthetic Conjugated Estrogens, B, Tacrolimus, Tadalafil, Tamoxifen, Tamsulosin, Tasimelteon, Tasosartan, Taurochenodeoxycholic acid, Tazemetostat, Telaprevir, Telithromycin, Temazepam, Temsirolimus, Tenapanor, Teniposide, Tenofovir, Tenofovir alafenamide, Tepotinib, Terbinafine, Terfenadine, Terguride, Terodiline, Tesmilifene, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone propionate, Testosterone undecanoate, Tetracycline, Tetrahydropalmatine, Tetrandrine, Tezacaftor, Theophylline, Thiamylal, Thiotepa, Tiagabine, Tianeptine, Ticagrelor, Tinidazole, Tiotropium, Tipranavir, Tirbanibulin, Tocofersolan, Tocopherol, Tofacitinib, Tolfenamic acid, Tolterodine, Tolvaptan, Toremifene, Trabectedin, Tramadol, Tranilast, Trastuzumab deruxtecan, Trastuzumab emtansine, Trazodone, Tretinoin, Triamcinolone, Triazolam, Triclabendazole, Trifarotene, Trimebutine, Trimethadione, Trimethoprim, Troleandomycin, Ubrogepant, Udenafil, Ulipristal, Umbralisib, Umifenovir, Upadacitinib, Valbenazine, Valdecoxib, Vandetanib, Vanoxerine, Vardenafil, Velpatasvir, Vemurafenib, Venetoclax, Venlafaxine, Verapamil, Vibegron, Vicriviroc, Vilanterol, Vilazodone, Vinblastine, Vincristine, Vindesine, Vinflunine, Vinorelbine, Vinpocetine, Vismodegib, Vitamin D, Vitamin E, Voclosporin, Vorapaxar, Voriconazole, Vortioxetine, Voxelotor, Voxilaprevir, Warfarin, WIN 55212-2, Yohimbine, Zafirlukast, Zaleplon, Zanubrutinib, Zidovudine, Zileuton, Ziprasidone, Zolpidem, Zomepirac, Zonisamide, Zopiclone, Zotepine, Zuclopenthixol
2	Cytochrome P450 3A4 inducers	Acetaminophen, Amcinonide, Aminoglutethimide, Amprenavir, Apalutamide, Aprepitant, Aprobarbital, Armodafinil, Artemether, Asunaprevir, Avasimibe, Azatadine, Barbital, Beclomethasone dipropionate, Betamethasone, Betamethasone phosphate, Bexarotene, Bosentan, Budesonide, Calcitriol, Carbamazepine, Cefradine, Cenobamate, Cerivastatin, Chlorphenesin, Chlorpromazine, Clevidipine, Clobazam, Clobetasol, Clobetasol propionate, Clocortolone acetate, Clofibrate, Cloprednol, Clozapine, Corticotropin, Cortisone, Cortisone acetate, Cortivazol, Cyclophosphamide, Dabrafenib, Deferasirox, Deflazacort, Delafloxacin, Desonide, Dexamethasone, Dexamethasone acetate, Dexamethasone isonicotinate, Dicloxacillin, Difluocortolone, Echinacea, Efavirenz, Enasidenib, Enzalutamide, Esketamine, Eslicarbazepine, Eslicarbazepine acetate, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Ethanol, Etoposide, Etravirine, Felbamate, Flucloxacillin, Flunisolide, Fluocinolone acetonide, Fluocinonide, Fluocortolone, Fluorometholone, Fluprednidene, Fluprednidene acetate, Fluticasone, Fluticasone furoate, Formestane, Fosaprepitant, Fosphenytoin, Genistein, Glycerol phenylbutyrate, Griseofulvin, Halometasone, Hydrocortamate, Hydrocortisone, Hydrocortisone aceponate, Hydrocortisone acetate, Hydrocortisone butyrate, Hydrocortisone probutate, Hydrocortisone succinate, Hydrocortisone valerate, Idelalisib, Ifosfamide, Isavuconazole, Isavuconazonium, Ivosidenib, Ketamine, Lansoprazole, Lenvatinib, Lesinurad, Lumacaftor, Medroxyprogesterone acetate, Medrysone, Melengestrol acetate, Meperidine, Meprednisone, Metamizole, Methadone, Methylprednisolone, Methylprednisolone hemisuccinate, Metyrapone, Midostaurin, Mifepristone, Mitotane, Modafinil, Mometasone, Mometasone furoate, Nafcillin, Nevirapine, Nifedipine, Norgestimate, Omeprazole, Oritavancin, Orlistat, Osimertinib, Oxcarbazepine, Oxiconazole, Paclitaxel, Paramethasone, Pegvisomant, Pentobarbital, Perampanel, Pexidartinib, Phenobarbital, Phenylbutazone, Phenytoin, Pioglitazone, Pitolisant, Pralsetinib, Prednisolone, Prednisolone acetate, Prednisolone hemisuccinate, Prednisolone phosphate, Prednisone, Prednisone acetate, Prednylidene, Primidone, Probenecid, Progesterone, Propacetamol, Quinine, Rifabutin, Rifampicin, Rifamycin, Rifapentine, Rifaximin, Rimexolone, Rofecoxib, Rufinamide, Sarilumab, Seratrodast, Siltuximab, St. John's Wort, Sulfinpyrazone, Tamoxifen, Terbinafine, Tesmilifene, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Thiamylal, Tocilizumab, Topiramate, Trametinib, Triamcinolone, Troglitazone, Vemurafenib, Vinblastine, Vitamin E, Warfarin
3	Cytochrome P450 3A4 inhibitors	6-Deoxyerythronolide B, Abametapir, Abemaciclib, Abiraterone, Acalabrutinib, Acetazolamide, Albuterol, Aldesleukin, Amiodarone, Amprenavir, Anastrozole, Aprepitant, Arsenic trioxide, Astemizole, Atazanavir, AVE9633, Azelastine, Azithromycin, Barnidipine, Benidipine, Berotralstat, Bicalutamide, Bifonazole, Black cohosh, Boceprevir, Bosutinib, Brefeldin A, Brentuximab vedotin, Bromocriptine, Bryostatin 1, Buprenorphine, Candicidin, Cannabidiol, Capsaicin, Carbomycin, Casimersen, Caspofungin, Cenobamate, Ceritinib, Cerivastatin, Cethromycin, Chloramphenicol, Chlorzoxazone, Cimetidine, Ciprofloxacin, Citalopram, Clarithromycin, Clascoterone, Clevidipine, Clindamycin, Clofazimine, Clozapine, Cobicistat, Colchicine, Coltuximab ravtansine, Conivaptan, Crizotinib, Curcumin, Curcumin sulfate, Cyclosporine, Cyproterone acetate, Dabrafenib, Dalfopristin, Danazol, Danoprevir, Dapoxetine, Darunavir, Dasatinib, Daunorubicin, Delavirdine, Desipramine, Desvenlafaxine, Dexamethasone, Dexamethasone acetate, Dexamethasone isonicotinate, Dextropropoxyphene, Diazepam, Diclofenac, Diethylstilbestrol, Dihydroergotamine, Diltiazem, Dimethyl sulfoxide, Dirithromycin, Ditiocarb, Docetaxel, Doramectin, Dovitinib, Doxorubicin, Doxycycline, Dronedarone, Duloxetine, Econazole, Edetate calcium disodium anhydrous, Edetate disodium anhydrous, Efavirenz, Efonidipine, Elexacaftor, Elvitegravir, Enasidenib, Epinephrine, Epofolate, Epothilone D, Eprinomectin, Ergotamine, Erlotinib, Erythromycin, Ethambutol, Ethanol, Etoposide, Etoricoxib, Ezetimibe, Fidaxomicin, Fluconazole, Fluoxetine, Flurithromycin, Fluticasone, Fluticasone furoate, Fluticasone propionate, Fluvastatin, Fluvoxamine, Fosamprenavir, Fosaprepitant, Fosnetupitant, Fostamatinib, Fusidic acid, Gefitinib, Ginkgo biloba, Glecaprevir, Glyburide, GPI-1485, Haloperidol, Hydralazine, Idelalisib, Ifosfamide, Imatinib, Indalpine, Indinavir, Indisulam, Irbesartan, Isavuconazole, Isavuconazonium, Isradipine, Itraconazole, Ivacaftor, Ketazolam, Ketoconazole, Kitasamycin, KOS-1584, Lanreotide, Lansoprazole, Lapatinib, Lenvatinib, Lercanidipine, Lestaurtinib, Letermovir, Levoketoconazole, Linagliptin, Lomustine, Lonafarnib, Loperamide, Lopinavir, Loratadine, Lorvotuzumab mertansine, Losartan, Lovastatin, Luliconazole, Manidipine, Medical Cannabis, Mefloquine, Menadione, Mequitazine, Methadone, Methimazole, Methylene blue, Methylergometrine, Metronidazole, Metyrapone, Mibefradil, Miconazole, Midazolam, Midecamycin, Midostaurin, Mifepristone, Milnacipran, Miocamycin, Mirtazapine, Mirvetuximab soravtansine, Mitemcinal, Mitoxantrone, Naloxone, Nefazodone, Nelfinavir, Netupitant, Niacin, Nicardipine, Nicotinamide, Nifedipine, Nilotinib, Nilvadipine, Nitric Oxide, Norfloxacin, Noscapine, Octreotide, Olanzapine, Olaparib, Oleandomycin, Omeprazole, Oritavancin, Orphenadrine, Osilodrostat, Osimertinib, Oxcarbazepine, Oxetacaine, Oxybutynin, Oxymetholone, Palbociclib, Paramethasone, Paroxetine, Pasireotide, Patupilone, Pazopanib, Peppermint oil, Pergolide, Pexidartinib, Phenelzine, Pilocarpine, Piperaquine, Piperine, Posaconazole, Pralsetinib, Primaquine, Quinidine, Quinine, Quinupristin, Rabeprazole, Raloxifene, Ranitidine, Ranolazine, Reboxetine, Regorafenib, Remacemide, Remdesivir, Resveratrol, Ribociclib, Ridaforolimus, Rifamycin, Rilpivirine, Rimegepant, Ritonavir, Rokitamycin, Roxithromycin, Rucaparib, Rutin, Sagopilone, Saquinavir, Saracatinib, Sarilumab, Selamectin, Seproxetine, Simeprevir, Sitaxentan, SN-38, Solithromycin, Somatostatin, Sorafenib, Stiripentol, Sulfanilamide, Sunitinib, Tamoxifen, Telaprevir, Telithromycin, Teniposide, Terfenadine, Tesmilifene, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Tetracycline, Ticagrelor, Tildipirosin, Tilmicosin, Tioconazole, Tipranavir, Tirbanibulin, Tofisopam, Topiroxostat, Toremifene, Tranylcypromine, Triclabendazole, Troleandomycin, Tylosin, Tylvalosin, Valproic acid, Vapreotide, Venetoclax, Verapamil, Vinblastine, Voclosporin, Voriconazole, WIN 55212-2, Zafirlukast, Zimelidine

	Interacting Group	Interacting Drugs
	Clotrimazole is a Cytochrome P450 2B6 inhibitor
1	Cytochrome P450 2B6 substrates	Amitriptyline, Amlodipine, Antipyrine, Apomorphine, Artemether, Artemisinin, Asunaprevir, Banoxantrone, Benzphetamine, Brivaracetam, Bupropion, Carbamazepine, Cenobamate, Cinnarizine, Cisapride, Clobazam, Clomethiazole, Clopidogrel, Clotiazepam, Cyclophosphamide, Dexloxiglumide, Dextromethorphan, Diazepam, Diclofenac, Domperidone, Efavirenz, Enasidenib, Epinastine, Esketamine, Estrone, Ethylmorphine, Fenfluramine, Flunitrazepam, Fluoxetine, Halothane, Hydrocodone, Ifosfamide, Imipramine, Irinotecan, Isoflurane, Istradefylline, Ixazomib, Ketamine, Ketobemidone, Lidocaine, Loperamide, Loratadine, Lorcaserin, Malathion, Meperidine, Mephenytoin, Methadone, Methoxyflurane, Methylphenobarbital, Methyltestosterone, Mexiletine, Mianserin, Nevirapine, Nicotine, Norgestimate, Osilodrostat, Ospemifene, Perampanel, Perhexiline, Permethrin, Phenytoin, Prasugrel, Promethazine, Propofol, Romidepsin, Ropivacaine, Selegiline, Seratrodast, Sertraline, Sevoflurane, Tamoxifen, Temazepam, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Tramadol, Tretinoin, Trifarotene, Valproic acid, Velpatasvir, Verapamil, Vortioxetine, Voxelotor
2	Cytochrome P450 2B6 inducers	Armodafinil, Artemether, Artemisinin, Atorvastatin, Betamethasone, Budesonide, Carbamazepine, Cenobamate, Cerivastatin, Cyclophosphamide, Dexamethasone, Dexamethasone acetate, Efavirenz, Enasidenib, Esketamine, Fluvastatin, Fosphenytoin, Hydrocortisone, Idelalisib, Isavuconazole, Isoflurane, Ivosidenib, Lemborexant, Letermovir, Lorlatinib, Lumacaftor, Metamizole, Methadone, Methylprednisolone, Midostaurin, Modafinil, Nevirapine, Nicardipine, Nifedipine, Nilotinib, Olaparib, Perampanel, Permethrin, Pexidartinib, Phenobarbital, Phenytoin, Pitolisant, Prednisolone phosphate, Prednisone, Rifabutin, Rifampicin, Rifamycin, Rifapentine, Ritonavir, Simvastatin, Sulfinpyrazone, Troglitazone, Vemurafenib, Zanubrutinib
3	Cytochrome P450 2B6 inhibitors	Abametapir, Abemaciclib, Amlodipine, Amprenavir, Azelastine, Cenobamate, Cisplatin, Clascoterone, Clopidogrel, Colchicine, Crisaborole, Crizotinib, Curcumin, Curcumin sulfate, Dabrafenib, Desipramine, Doxorubicin, Duloxetine, Elexacaftor, Enasidenib, Enzalutamide, Ethanol, Fluvoxamine, Itraconazole, Ketoconazole, Lenvatinib, Lopinavir, Manidipine, Memantine, Menadione, Methimazole, Methylene blue, Miconazole, Modafinil, Nelfinavir, Nitric Oxide, Opicapone, Orphenadrine, Paroxetine, Pexidartinib, Phencyclidine, Piperaquine, Quazepam, Quinidine, Raloxifene, Regorafenib, Rifamycin, Rilpivirine, Ritonavir, Roxithromycin, Selegiline, Sertraline, Simvastatin, Sorafenib, Sulfaphenazole, Tamoxifen, Thiotepa, Ticlopidine, Tirbanibulin, Triclabendazole, Voriconazole
4	Cytochrome P450 2B6 activators	Verapamil

	Interacting Group	Interacting Drugs
	Clotrimazole is a Cytochrome P450 2B6 inducer
1	Cytochrome P450 2B6 substrates	Amitriptyline, Amlodipine, Antipyrine, Apomorphine, Artemether, Artemisinin, Asunaprevir, Banoxantrone, Benzphetamine, Brivaracetam, Bupropion, Carbamazepine, Cenobamate, Cinnarizine, Cisapride, Clobazam, Clomethiazole, Clopidogrel, Clotiazepam, Cyclophosphamide, Dexloxiglumide, Dextromethorphan, Diazepam, Diclofenac, Domperidone, Efavirenz, Enasidenib, Epinastine, Esketamine, Estrone, Ethylmorphine, Fenfluramine, Flunitrazepam, Fluoxetine, Halothane, Hydrocodone, Ifosfamide, Imipramine, Irinotecan, Isoflurane, Istradefylline, Ixazomib, Ketamine, Ketobemidone, Lidocaine, Loperamide, Loratadine, Lorcaserin, Malathion, Meperidine, Mephenytoin, Methadone, Methoxyflurane, Methylphenobarbital, Methyltestosterone, Mexiletine, Mianserin, Nevirapine, Nicotine, Norgestimate, Osilodrostat, Ospemifene, Perampanel, Perhexiline, Permethrin, Phenytoin, Prasugrel, Promethazine, Propofol, Romidepsin, Ropivacaine, Selegiline, Seratrodast, Sertraline, Sevoflurane, Tamoxifen, Temazepam, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Tramadol, Tretinoin, Trifarotene, Valproic acid, Velpatasvir, Verapamil, Vortioxetine, Voxelotor
2	Cytochrome P450 2B6 inducers	Armodafinil, Artemether, Artemisinin, Atorvastatin, Betamethasone, Budesonide, Carbamazepine, Cenobamate, Cerivastatin, Cyclophosphamide, Dexamethasone, Dexamethasone acetate, Efavirenz, Enasidenib, Esketamine, Fluvastatin, Fosphenytoin, Hydrocortisone, Idelalisib, Isavuconazole, Isoflurane, Ivosidenib, Lemborexant, Letermovir, Lorlatinib, Lumacaftor, Metamizole, Methadone, Methylprednisolone, Midostaurin, Modafinil, Nevirapine, Nicardipine, Nifedipine, Nilotinib, Olaparib, Perampanel, Permethrin, Pexidartinib, Phenobarbital, Phenytoin, Pitolisant, Prednisolone phosphate, Prednisone, Rifabutin, Rifampicin, Rifamycin, Rifapentine, Ritonavir, Simvastatin, Sulfinpyrazone, Troglitazone, Vemurafenib, Zanubrutinib
3	Cytochrome P450 2B6 inhibitors	Abametapir, Abemaciclib, Amlodipine, Amprenavir, Azelastine, Cenobamate, Cisplatin, Clascoterone, Clopidogrel, Colchicine, Crisaborole, Crizotinib, Curcumin, Curcumin sulfate, Dabrafenib, Desipramine, Doxorubicin, Duloxetine, Elexacaftor, Enasidenib, Enzalutamide, Ethanol, Fluvoxamine, Itraconazole, Ketoconazole, Lenvatinib, Lopinavir, Manidipine, Memantine, Menadione, Methimazole, Methylene blue, Miconazole, Modafinil, Nelfinavir, Nitric Oxide, Opicapone, Orphenadrine, Paroxetine, Pexidartinib, Phencyclidine, Piperaquine, Quazepam, Quinidine, Raloxifene, Regorafenib, Rifamycin, Rilpivirine, Ritonavir, Roxithromycin, Selegiline, Sertraline, Simvastatin, Sorafenib, Sulfaphenazole, Tamoxifen, Thiotepa, Ticlopidine, Tirbanibulin, Triclabendazole, Voriconazole
4	Cytochrome P450 2B6 activators	Verapamil

	Interacting Group	Interacting Drugs
	Clotrimazole is a Cytochrome P450 2A6 inhibitor
1	Cytochrome P450 2A6 substrates	Acetaminophen, Antipyrine, Apremilast, Arformoterol, Artesunate, Asunaprevir, Azelastine, Cenobamate, Chlorzoxazone, Cinnarizine, Cisapride, Clomethiazole, Clozapine, Cyclophosphamide, Dapagliflozin, Flunarizine, Flunitrazepam, Fluorouracil, Flurazepam, Formoterol, Halothane, Ifosfamide, Letrozole, Lidocaine, Lonafarnib, Lorcaserin, Methoxyflurane, Metronidazole, Montelukast, Nevirapine, Nicotine, Nifedipine, Norethisterone, Phenacetin, Phenytoin, Plitidepsin, Selegiline, Sevoflurane, Tamoxifen, Tegafur, Tegafur-uracil, Tretinoin, Valproic acid, Vortioxetine, Zidovudine
2	Cytochrome P450 2A6 inhibitors	Amiodarone, Amphetamine, Azelastine, Ethambutol, Fenofibrate, Fomepizole, Isoniazid, Ketoconazole, Letrozole, Memantine, Menadione, Methimazole, Methoxsalen, Metyrapone, Miconazole, Nicotine, Nilvadipine, Pilocarpine, Rosiglitazone, Selegiline, Seratrodast, Tranylcypromine, Triclabendazole
3	Cytochrome P450 2A6 inducers	Betamethasone, Budesonide, Dexamethasone, Dexamethasone acetate, Eletriptan, Hydrocortisone, Methylprednisolone, Pentobarbital, Phenobarbital, Prednisolone phosphate, Prednisone, Progesterone, Rifampicin, Valproic acid

	Interacting Group	Interacting Drugs
	Clotrimazole is a Cytochrome P450 2C9 inhibitor
1	Cytochrome P450 2C9 inhibitors	Abemaciclib, Abiraterone, Acetyl sulfisoxazole, Agomelatine, Amiodarone, Amodiaquine, Anastrozole, Aprepitant, Armodafinil, Atazanavir, Atorvastatin, Atovaquone, Avasimibe, Azelastine, Belinostat, Benzbromarone, Bicalutamide, Black cohosh, Bortezomib, Candesartan, Capecitabine, Casimersen, Ceritinib, Cerivastatin, Cimetidine, Cisapride, Cisplatin, Clascoterone, Clevidipine, Clinafloxacin, Clopidogrel, Crisaborole, Curcumin, Curcumin sulfate, Cyclizine, Delavirdine, Dexloxiglumide, Diacerein, Diethylstilbestrol, Doconexent, Dosulepin, Efavirenz, Elexacaftor, Enasidenib, Epinephrine, Estrone sulfate, Ethambutol, Ethanol, Etoricoxib, Etravirine, Felbamate, Felodipine, Fenofibrate, Flecainide, Floxuridine, Fluconazole, Fluorouracil, Fluoxetine, Fluvastatin, Fluvoxamine, Gefitinib, Gemfibrozil, Genistein, Ginkgo biloba, Glyburide, Imatinib, Iproniazid, Isavuconazole, Isoniazid, Ketoconazole, Ketoprofen, Lansoprazole, Leflunomide, Lenvatinib, Levofloxacin, Lifitegrast, Lobeglitazone, Lopinavir, Lumacaftor, Manidipine, Medical Cannabis, Medroxyprogesterone acetate, Mefenamic acid, Menadione, Methimazole, Methylene blue, Metronidazole, Miconazole, Midostaurin, Mifepristone, Modafinil, Nabilone, Nicardipine, Nifedipine, Nilotinib, Noscapine, Olanzapine, Opicapone, Oritavancin, Oxandrolone, Paroxetine, Pexidartinib, Phenylbutazone, Phenytoin, Pralsetinib, Pranlukast, Probenecid, Progesterone, Promethazine, Quinidine, Rabeprazole, Regorafenib, Rhein, Rifamycin, Rilpivirine, Rucaparib, Seproxetine, Sertraline, Sildenafil, Simvastatin, Sitaxentan, Sorafenib, Stiripentol, Sulconazole, Sulfadiazine, Sulfadimethoxine, Sulfamethizole, Sulfamethoxazole, Sulfamoxole, Sulfaphenazole, Sulfapyridine, Sulfinpyrazone, Sulfisoxazole, Suprofen, Tamoxifen, Teniposide, Ticagrelor, Ticlopidine, Tienilic acid, Tirbanibulin, Tolcapone, Topiroxostat, Torasemide, Tranylcypromine, Troglitazone, Ubrogepant, Valdecoxib, Valproic acid, Vemurafenib, Verapamil, Vismodegib, Voriconazole, Zafirlukast, Zucapsaicin
2	Cytochrome P450 2C9 substrates	(R)-warfarin, (S)-Warfarin, Aceclofenac, Acenocoumarol, Acetohexamide, Acetylsalicylic acid, Alosetron, Alprazolam, Aminophenazone, Amitriptyline, Amprenavir, Antipyrine, Apixaban, Arachidonic Acid, Arformoterol, Artemether, Asunaprevir, Atazanavir, Avanafil, Avapritinib, Azelastine, Bioallethrin, Bortezomib, Bosentan, Brivaracetam, Buprenorphine, Bupropion, Cabozantinib, Caffeine, Candesartan, Candesartan cilexetil, Cannabidiol, Capecitabine, Capravirine, Carbutamide, Carvedilol, Celecoxib, Chlorpropamide, Cinnarizine, Clopidogrel, Clozapine, Coumarin, Cyclophosphamide, Dacomitinib, Dapagliflozin, Dapsone, Desogestrel, Dexibuprofen, Dexloxiglumide, Dextromethorphan, Diazepam, Diclofenac, Dicoumarol, Diphenhydramine, Doconexent, Dolasetron, Donepezil, Dorzolamide, Doxazosin, Doxepin, Dronabinol, Duloxetine, Eletriptan, Enasidenib, Enzalutamide, Erdafitinib, Esketamine, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estrone, Estrone sulfate, Ethinylestradiol, Etodolac, Etoricoxib, Etravirine, Febuxostat, Fenfluramine, Fluindione, Flunarizine, Flunitrazepam, Fluoxetine, Flurbiprofen, Fluvastatin, Formoterol, Fosphenytoin, Glibornuride, Gliclazide, Glimepiride, Glipizide, Gliquidone, Glisoxepide, Glyburide, Haloperidol, Halothane, Hexobarbital, Hydromorphone, Ibuprofen, Idarubicin, Ifosfamide, Imatinib, Indisulam, Indomethacin, Irbesartan, Istradefylline, Ixazomib, Ketamine, Ketobemidone, Ketoprofen, Ketorolac, Lacosamide, Leflunomide, Lesinurad, Licofelone, Lidocaine, Lonafarnib, Loratadine, Lornoxicam, Losartan, Lumiracoxib, Lynestrenol, Medical Cannabis, Mefenamic acid, Melatonin, Meloxicam, Mephenytoin, Mestranol, Metahexamide, Methadone, Methoxyflurane, Moclobemide, Montelukast, Nabiximols, Nabumetone, Naproxen, Nateglinide, Netupitant, Niclosamide, Nicotine, Norgestimate, Oliceridine, Olodaterol, Omeprazole, Ondansetron, Ospemifene, Paramethadione, Parecoxib, Perphenazine, Phenacetin, Phenobarbital, Phenprocoumon, Phenylbutazone, Phenytoin, Piperaquine, Pirfenidone, Piroxicam, Pitavastatin, Prasugrel, Primidone, Progesterone, Proguanil, Promazine, Propacetamol, Propofol, Quazepam, Quinidine, Quinine, Ramelteon, Rimegepant, Rofecoxib, Rosiglitazone, Rosuvastatin, Rupatadine, Ruxolitinib, Salicylic acid, Selegiline, Selumetinib, Seratrodast, Sertraline, Sildenafil, Siponimod, Sitaxentan, Sulfamethoxazole, Suprofen, Tamoxifen, Tapentadol, Temazepam, Tenoxicam, Terbinafine, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Thalidomide, Thiamylal, Tolazamide, Tolbutamide, Tolterodine, Torasemide, Trabectedin, Tranilast, Treprostinil, Tretinoin, Triclabendazole, Trifarotene, Trimethadione, Trimethoprim, Trimipramine, Troglitazone, Umbralisib, Umifenovir, Valdecoxib, Valproic acid, Valsartan, Verapamil, Vicriviroc, Vismodegib, Voriconazole, Vortioxetine, Voxelotor, Warfarin, Ximelagatran, Zafirlukast, Zaltoprofen, Zidovudine, Zileuton, Zolpidem, Zopiclone
3	Cytochrome P450 2C9 inducers	Alpelisib, Apalutamide, Aprepitant, Avatrombopag, Betamethasone, Bosentan, Budesonide, Carbamazepine, Dabrafenib, Dapsone, Delafloxacin, Enzalutamide, Fosaprepitant, Fosphenytoin, Hydrocortisone, Isavuconazole, Ivosidenib, Lansoprazole, Letermovir, Lopinavir, Lumacaftor, Methylprednisolone, Midostaurin, Modafinil, Nelfinavir, Nevirapine, Nifedipine, Peginterferon alfa-2b, Phenobarbital, Phenytoin, Pralsetinib, Prednisolone phosphate, Prednisone, Primidone, Rifabutin, Rifampicin, Rifamycin, Rifapentine, Ritonavir, Secobarbital, Vigabatrin, Warfarin
4	Cytochrome P450 2C9 inactivators	Suprofen

	Interacting Group	Interacting Drugs
	Clotrimazole is a Cytochrome P450 2E1 inhibitor
1	Cytochrome P450 2E1 substrates	1,2-dichlorobenzene, Acetaminophen, Almotriptan, Aminophylline, Aniline, Antipyrine, Benzyl alcohol, Bupropion, Caffeine, Capsaicin, Carvedilol, Cenobamate, Chlorzoxazone, Clevidipine, Dacarbazine, Dalfampridine, Dapsone, Desflurane, Dexloxiglumide, Dexmedetomidine, Dichlorobenzene, Dorzolamide, Enflurane, Enfuvirtide, Estrone, Ethanol, Ethosuximide, Etoposide, Felbamate, Fingolimod, Fomepizole, GTS-21, Halothane, Iloperidone, Isoflurane, Isoniazid, Lonafarnib, Methoxyflurane, Mexiletine, Mitoxantrone, N-Methyl-N-(Methylbenzyl)Formamide, N,N-dimethylformamide, Nicardipine, Nicotinamide, Nicotine, Nilvadipine, Ondansetron, Paramethadione, Phenacetin, Phenobarbital, Phenytoin, Pirfenidone, Plitidepsin, Primidone, Propacetamol, Quinidine, Quinine, Selumetinib, Sertraline, Sevoflurane, Sildenafil, Tamoxifen, Tegafur, Theobromine, Theophylline, Thiamylal, Tirapazamine, Trabectedin, Trimethadione, Umifenovir, Verapamil
2	Cytochrome P450 2E1 inhibitors	Ademetionine, Aldesleukin, Alosetron, Azelastine, Bifonazole, Bromazepam, Chlorpromazine, Chlorzoxazone, Cimetidine, Clascoterone, Clonazepam, Desipramine, Dexfenfluramine, Diacerein, Diazepam, Diclofenac, Diethylstilbestrol, Disulfiram, Ditiocarb, Econazole, Ellagic acid, Ethambutol, Etoricoxib, Favipiravir, Flunitrazepam, Fluphenazine, Flurazepam, Fomepizole, Imipramine, Indisulam, Isoniazid, Isosorbide dinitrate, Itraconazole, Menadione, Methimazole, Methotrimeprazine, Metyrapone, Miconazole, Midostaurin, Nabilone, Niacin, Nicotinamide, Nicotine, Nifedipine, Nitrazepam, Nortriptyline, Orphenadrine, Osilodrostat, Propofol, Rhein, Rilpivirine, Rufinamide, Sildenafil, Sulfanilamide, Tegaserod, Thioridazine, Ticlopidine, Tioconazole, Vayarin, Zucapsaicin
3	Cytochrome P450 2E1 inducers	Clofibrate, Colchicine, Delafloxacin, Dexamethasone, Dexamethasone acetate, Ethanol, Fomepizole, Glycerin, Isoniazid, Mitoxantrone, Nicotine, Phenelzine, Phenobarbital, Piperaquine, Primidone, Rifampicin, Streptozocin

	Interacting Group	Interacting Drugs
	Clotrimazole is a Cytochrome P450 3A7 inducer
1	Cytochrome P450 3A7 substrates	Alfentanil, Alprazolam, Aripiprazole, Aripiprazole lauroxil, Astemizole, Atorvastatin, Buprenorphine, Buspirone, Cerivastatin, Chlorpheniramine, Cilostazol, Cisapride, Cobicistat, Copanlisib, Daclatasvir, Dapsone, Dexamethasone, Dexamethasone acetate, Dextromethorphan, Diazepam, Diltiazem, Docetaxel, Domperidone, Elbasvir, Erythromycin, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Felodipine, Fentanyl, Finasteride, Fluticasone, Fluticasone furoate, Fluticasone propionate, Glyburide, Haloperidol, Hydrocortisone, Hydrocortisone aceponate, Hydrocortisone acetate, Hydrocortisone butyrate, Hydrocortisone cypionate, Hydrocortisone phosphate, Hydrocortisone probutate, Hydrocortisone valerate, Idelalisib, Iloperidone, Imatinib, Imipramine, Irinotecan, Lercanidipine, Levacetylmethadol, Lidocaine, Methadone, Metronidazole, Midazolam, Nateglinide, Nevirapine, Nisoldipine, Nitrendipine, Ondansetron, Paclitaxel, Phenytoin, Pimozide, Prasterone, Prasterone sulfate, Praziquantel, Progesterone, Propranolol, Quinidine, Quinine, Risdiplam, Ritonavir, Salmeterol, Saquinavir, Sildenafil, Sirolimus, Sorafenib, Sunitinib, Tamoxifen, Temsirolimus, Terfenadine, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Trazodone, Tretinoin, Triamcinolone, Triazolam, Vincristine, Zaleplon
2	Cytochrome P450 3A7 inhibitors	Cannabidiol, Chloramphenicol, Ciprofloxacin, Cobicistat, Delavirdine, Diltiazem, Erythromycin, Gestodene, Idelalisib, Imatinib, Indinavir, Itraconazole, Letermovir, Medical Cannabis, Menadione, Mibefradil, Nabiximols, Nelfinavir, Norfloxacin, Oxymetholone, Phenelzine, Prasterone, Progesterone, Ritonavir, Rucaparib, Saquinavir, Seproxetine, Troglitazone, Troleandomycin, Voriconazole
3	Cytochrome P450 3A7 inducers	Dexamethasone, Dexamethasone acetate, Efavirenz, Midostaurin, Phenobarbital, Phenytoin, Rifampicin, Triamcinolone

	Interacting Group	Interacting Drugs
	Clotrimazole is a P-glycoprotein 1 inhibitor
1	P-glycoprotein 1 inducers	Acetylsalicylic acid, Aldosterone, Amiodarone, Amprenavir, Apalutamide, Atazanavir, Beclomethasone dipropionate, Betamethasone phosphate, Carbamazepine, Cholic Acid, Cimetidine, Colchicine, Cortisone acetate, Darunavir, Daunorubicin, Dexamethasone, Dexamethasone acetate, Diclofenac, Digoxin, Doxorubicin, Estriol, Estrone, Etravirine, Hydrocortisone, Indinavir, Ivermectin, Levothyroxine, Liothyronine, Liotrix, Lopinavir, Lumacaftor, Methylprednisolone, Mifepristone, Mitoxantrone, Nefazodone, Nelfinavir, Nifedipine, Phenobarbital, Platelet Activating Factor, Prednisolone phosphate, Prednisone, Progesterone, Propofol, Reserpine, Rifabutin, Rifampicin, Ritonavir, Saquinavir, Sirolimus, Spironolactone, St. John's Wort, Streptozocin, Tacrolimus, Tamoxifen, Tesmilifene, Tipranavir, Trazodone, Vinblastine, Vincristine
2	P-glycoprotein 1 inhibitors	Abemaciclib, Acetaminophen, Afatinib, Alectinib, Alfentanil, Alpelisib, Amiodarone, Amlodipine, Amodiaquine, Amsacrine, Arsenic trioxide, Astemizole, Asunaprevir, Atazanavir, Atorvastatin, Atovaquone, Axitinib, Azelastine, Azithromycin, Benzocaine, Bepridil, Berotralstat, Bicalutamide, Biricodar, Bisoprolol, Boceprevir, Bromocriptine, Buprenorphine, Buspirone, Cabazitaxel, Canagliflozin, Candesartan, Candesartan cilexetil, Captopril, Carfilzomib, Carvedilol, Caspofungin, Ceftriaxone, Cethromycin, Cetirizine, Chloroquine, Chlorpromazine, Chlorprothixene, Cholesterol, Cilazapril, Citalopram, Clarithromycin, Clofazimine, Clomipramine, Cobicistat, Colforsin, Concanamycin A, Conivaptan, Crizotinib, Curcumin, Cyclosporine, Daclatasvir, Dacomitinib, Dactinomycin, Darunavir, Dasatinib, Daunorubicin, Desipramine, Desloratadine, Desmethylsertraline, Dexamethasone, Dexamethasone acetate, Dexniguldipine, Dexverapamil, Digoxin, Dihydroergotamine, Diltiazem, Dipyridamole, Dofequidar, Dovitinib, Doxazosin, Doxorubicin, Dronabinol, Dronedarone, Duloxetine, Elacridar, Elagolix, Elbasvir, Elexacaftor, Emopamil, Enalapril, Enasidenib, Entrectinib, Enzalutamide, Erdafitinib, Ergometrine, Ergotamine, Erlotinib, Erythromycin, Esomeprazole, Estramustine, Etoposide, Everolimus, Favipiravir, Fedratinib, Felodipine, Fentanyl, Fingolimod, Flibanserin, Fluconazole, Fluoxetine, Flupentixol, Fluphenazine, Flurazepam, Fluvoxamine, Galantamine, Gallopamil, Gefitinib, Genistein, Glasdegib, Glecaprevir, Glyburide, Gramicidin D, Grepafloxacin, Haloperidol, HM-30181, Hycanthone, Hydroxychloroquine, Idelalisib, Imatinib, Indinavir, Indomethacin, Isavuconazole, Isavuconazonium, Istradefylline, Itraconazole, Ivacaftor, Ivermectin, Ivosidenib, Ixabepilone, Ketoconazole, Lamotrigine, Laniquidar, Lansoprazole, Lapatinib, Lasmiditan, Lenvatinib, Letermovir, Levofloxacin, Lidocaine, Lomerizine, Lomitapide, Lonafarnib, Lopinavir, Loratadine, Losartan, Lovastatin, Lumacaftor, Lurbinectedin, Medroxyprogesterone acetate, Mefloquine, Megestrol acetate, Methadone, Methylene blue, Metronidazole, Mibefradil, Miconazole, Mifepristone, Mirabegron, Mitotane, Mitoxantrone, Naproxen, Nefazodone, Nelfinavir, Neratinib, Netupitant, Nicardipine, Niguldipine, Nilotinib, Nintedanib, Nisoldipine, Nitrendipine, Norethisterone, Norgestimate, Olaparib, Omeprazole, ONT-093, Paclitaxel, Palbociclib, Paliperidone, Pantoprazole, Paroxetine, Pemigatinib, Pibrentasvir, Pimozide, Piperine, Polyethylene glycol, Polyethylene glycol 400, Ponatinib, Posaconazole, Pralsetinib, Prazosin, Primaquine, Progesterone, Promethazine, Propafenone, Protriptyline, Quercetin, Quinacrine, Quinidine, Quinine, Ranitidine, Ranolazine, Reboxetine, Regorafenib, Relugolix, Reserpine, Reversin 121, Rifamycin, Rilpivirine, Ripretinib, Ritonavir, Rolapitant, Rucaparib, Salinomycin, Saquinavir, Sarecycline, Selegiline, Selpercatinib, Sertraline, Sildenafil, Simeprevir, Simvastatin, Sirolimus, Sorafenib, Staurosporine, Sunitinib, Tacrolimus, Tamoxifen, Tariquidar, Taurocholic acid, Telaprevir, Telmisartan, Temsirolimus, Tenofovir disoproxil, Tepotinib, Terazosin, Terfenadine, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Tetrandrine, Tezacaftor, Ticagrelor, Tipifarnib, Tipranavir, Tolvaptan, Trifluoperazine, Triflupromazine, Troleandomycin, Umbralisib, Upadacitinib, Valinomycin, Valspodar, Vandetanib, Vardenafil, Velpatasvir, Vemurafenib, Venetoclax, Venlafaxine, Verapamil, Vinblastine, Vincristine, Voacamine, Voclosporin, Voxilaprevir, Zimelidine, Zonisamide, Zosuquidar
3	P-glycoprotein 1 substrates	Abemaciclib, Acebutolol, Acenocoumarol, Acetaminophen, Acetylsalicylic acid, Afatinib, Albendazole, Aldosterone, Alfuzosin, Aliskiren, Alitretinoin, alpha-Tocopherol acetate, Ambrisentan, Amitriptyline, Amlodipine, Amprenavir, Anastrozole, Apixaban, Apremilast, Artesunate, Asunaprevir, Atazanavir, Atorvastatin, Avanafil, Avatrombopag, Axitinib, Azathioprine, Azithromycin, Baricitinib, Beclomethasone dipropionate, Belantamab mafodotin, Belinostat, Berotralstat, Betamethasone, Betamethasone phosphate, Betrixaban, Bisoprolol, Bortezomib, Bosutinib, Bromocriptine, Budesonide, Cabazitaxel, Cabergoline, Cabotegravir, Camptothecin, Canagliflozin, Capmatinib, Carfilzomib, Celecoxib, Ceritinib, Cerivastatin, Cethromycin, Cetirizine, Chloramphenicol succinate, Chloroquine, Chlorpromazine, Cimetidine, Ciprofloxacin, Citalopram, Clarithromycin, Clindamycin, Clobazam, Clofazimine, Clomifene, Clopidogrel, Clozapine, Cobimetinib, Colchicine, Conjugated estrogens, Copanlisib, Cortisone acetate, Crizotinib, Cyclosporine, Dabigatran etexilate, Dabrafenib, Daclatasvir, Dacomitinib, Dactinomycin, Dapagliflozin, Darolutamide, Darunavir, Dasabuvir, Dasatinib, Daunorubicin, Debrisoquine, Dexamethasone, Dexamethasone acetate, Diazepam, Diethylstilbestrol, Digitoxin, Digoxin, Diltiazem, Dipyridamole, Docetaxel, Dolutegravir, Domperidone, Doxepin, Doxorubicin, Duvelisib, Edoxaban, Elagolix, Elbasvir, Eletriptan, Elexacaftor, Eliglustat, Empagliflozin, Enasidenib, Enfortumab vedotin, Entrectinib, Epinastine, Erdafitinib, Erlotinib, Ertugliflozin, Erythromycin, Escitalopram, Esomeprazole, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estriol, Estrone, Ethinylestradiol, Etoposide, Everolimus, Ezetimibe, Fedratinib, Fesoterodine, Fexofenadine, Fidaxomicin, Filgotinib, Flecainide, Fluticasone, Fluticasone furoate, Fluticasone propionate, Fostemsavir, Gefitinib, Gemcitabine, Gilteritinib, Glasdegib, Glecaprevir, Gramicidin D, Grapiprant, Grazoprevir, Grepafloxacin, Haloperidol, Hydrocortisone, Hydroxyzine, Ibuprofen, Idelalisib, Imatinib, Imipramine, Indacaterol, Indinavir, Indomethacin, Inotuzumab ozogamicin, Irinotecan, Ivermectin, Ivosidenib, Ixabepilone, Ketazolam, Lamivudine, Lamotrigine, Lansoprazole, Larotrectinib, Lasmiditan, Ledipasvir, Lefamulin, Lemborexant, Lenalidomide, Lenvatinib, Letermovir, Letrozole, Levamlodipine, Levetiracetam, Levofloxacin, Levomilnacipran, Linagliptin, Lonafarnib, Loperamide, Loratadine, Losartan, Lurbinectedin, Lusutrombopag, Medrysone, Mefloquine, Meperidine, Methotrexate, Methylene blue, Methylprednisolone, Metoclopramide, Mibefradil, Mirabegron, Mitoxantrone, Monensin, Morphine, Mycophenolate mofetil, Nadolol, Naloxone, Nelfinavir, Nicardipine, Nifedipine, Nilotinib, Nintedanib, Nitrofurantoin, Nizatidine, Nortriptyline, Octreotide, Odanacatib, Olanzapine, Olaparib, Olopatadine, Omadacycline, Ombitasvir, Omeprazole, Opicapone, Osimertinib, Oxcarbazepine, Ozanimod, Paclitaxel, Palbociclib, Paliperidone, Panobinostat, Pantoprazole, Paritaprevir, Pazopanib, Pemigatinib, Pentazocine, Phenobarbital, Phenytoin, Pibrentasvir, Pitavastatin, Platelet Activating Factor, Pomalidomide, Ponatinib, Posaconazole, Pralsetinib, Pravastatin, Prazosin, Prednisolone, Prednisolone acetate, Prednisolone phosphate, Prednisone, Progesterone, Propranolol, Prucalopride, Quetiapine, Quinidine, Quinine, Raloxifene, Ranitidine, Ranolazine, Regorafenib, Relugolix, Remdesivir, Reserpine, Revefenacin, Rhodamine 6G, Rifamycin, Rimegepant, Ripretinib, Risdiplam, Risperidone, Ritonavir, Rivaroxaban, Romidepsin, Rucaparib, Saquinavir, Selexipag, Selpercatinib, Selumetinib, Sildenafil, Silodosin, Simeprevir, Sitagliptin, Sofosbuvir, Somatostatin, Somatotropin, Sorafenib, Sparfloxacin, Sphingosine, Stanolone, Stanolone acetate, Sulpiride, Sumatriptan, Tacrine, Tacrolimus, Talazoparib, Talinolol, Tamoxifen, Taurocholic acid, Tazemetostat, Technetium Tc-99m sestamibi, Tegaserod, Telaprevir, Temozolomide, Temsirolimus, Tenofovir, Tenofovir alafenamide, Tenofovir disoproxil, Tepotinib, Testosterone propionate, Tezacaftor, Ticagrelor, Timolol, Tipranavir, Tolvaptan, Topiramate, Topotecan, Toremifene, Trastuzumab deruxtecan, Trastuzumab emtansine, Trilaciclib, Trimethoprim, Trimipramine, Tucatinib, Ubidecarenone, Ubrogepant, Umeclidinium, Upadacitinib, Valinomycin, Vardenafil, Vecuronium, Velpatasvir, Vemurafenib, Venetoclax, Venlafaxine, Verapamil, Vericiguat, Vibegron, Vinblastine, Vincristine, Vinflunine, Vismodegib, Voclosporin, Voxilaprevir, Zanubrutinib, Zidovudine
4	P-glycoprotein 1 modulators	Acetylsalicylic acid, Avapritinib, Prazosin
5	P-glycoprotein 1 transporters	Ledipasvir, Tocopherol
6	P-glycoprotein 1 binders	Technetium Tc-99m tetrofosmin
7	P-glycoprotein 1 antagonists	Tocofersolan

	Interacting Group	Interacting Drugs
	Clotrimazole is a P-glycoprotein 1 inducer
1	P-glycoprotein 1 inducers	Acetylsalicylic acid, Aldosterone, Amiodarone, Amprenavir, Apalutamide, Atazanavir, Beclomethasone dipropionate, Betamethasone phosphate, Carbamazepine, Cholic Acid, Cimetidine, Colchicine, Cortisone acetate, Darunavir, Daunorubicin, Dexamethasone, Dexamethasone acetate, Diclofenac, Digoxin, Doxorubicin, Estriol, Estrone, Etravirine, Hydrocortisone, Indinavir, Ivermectin, Levothyroxine, Liothyronine, Liotrix, Lopinavir, Lumacaftor, Methylprednisolone, Mifepristone, Mitoxantrone, Nefazodone, Nelfinavir, Nifedipine, Phenobarbital, Platelet Activating Factor, Prednisolone phosphate, Prednisone, Progesterone, Propofol, Reserpine, Rifabutin, Rifampicin, Ritonavir, Saquinavir, Sirolimus, Spironolactone, St. John's Wort, Streptozocin, Tacrolimus, Tamoxifen, Tesmilifene, Tipranavir, Trazodone, Vinblastine, Vincristine
2	P-glycoprotein 1 inhibitors	Abemaciclib, Acetaminophen, Afatinib, Alectinib, Alfentanil, Alpelisib, Amiodarone, Amlodipine, Amodiaquine, Amsacrine, Arsenic trioxide, Astemizole, Asunaprevir, Atazanavir, Atorvastatin, Atovaquone, Axitinib, Azelastine, Azithromycin, Benzocaine, Bepridil, Berotralstat, Bicalutamide, Biricodar, Bisoprolol, Boceprevir, Bromocriptine, Buprenorphine, Buspirone, Cabazitaxel, Canagliflozin, Candesartan, Candesartan cilexetil, Captopril, Carfilzomib, Carvedilol, Caspofungin, Ceftriaxone, Cethromycin, Cetirizine, Chloroquine, Chlorpromazine, Chlorprothixene, Cholesterol, Cilazapril, Citalopram, Clarithromycin, Clofazimine, Clomipramine, Cobicistat, Colforsin, Concanamycin A, Conivaptan, Crizotinib, Curcumin, Cyclosporine, Daclatasvir, Dacomitinib, Dactinomycin, Darunavir, Dasatinib, Daunorubicin, Desipramine, Desloratadine, Desmethylsertraline, Dexamethasone, Dexamethasone acetate, Dexniguldipine, Dexverapamil, Digoxin, Dihydroergotamine, Diltiazem, Dipyridamole, Dofequidar, Dovitinib, Doxazosin, Doxorubicin, Dronabinol, Dronedarone, Duloxetine, Elacridar, Elagolix, Elbasvir, Elexacaftor, Emopamil, Enalapril, Enasidenib, Entrectinib, Enzalutamide, Erdafitinib, Ergometrine, Ergotamine, Erlotinib, Erythromycin, Esomeprazole, Estramustine, Etoposide, Everolimus, Favipiravir, Fedratinib, Felodipine, Fentanyl, Fingolimod, Flibanserin, Fluconazole, Fluoxetine, Flupentixol, Fluphenazine, Flurazepam, Fluvoxamine, Galantamine, Gallopamil, Gefitinib, Genistein, Glasdegib, Glecaprevir, Glyburide, Gramicidin D, Grepafloxacin, Haloperidol, HM-30181, Hycanthone, Hydroxychloroquine, Idelalisib, Imatinib, Indinavir, Indomethacin, Isavuconazole, Isavuconazonium, Istradefylline, Itraconazole, Ivacaftor, Ivermectin, Ivosidenib, Ixabepilone, Ketoconazole, Lamotrigine, Laniquidar, Lansoprazole, Lapatinib, Lasmiditan, Lenvatinib, Letermovir, Levofloxacin, Lidocaine, Lomerizine, Lomitapide, Lonafarnib, Lopinavir, Loratadine, Losartan, Lovastatin, Lumacaftor, Lurbinectedin, Medroxyprogesterone acetate, Mefloquine, Megestrol acetate, Methadone, Methylene blue, Metronidazole, Mibefradil, Miconazole, Mifepristone, Mirabegron, Mitotane, Mitoxantrone, Naproxen, Nefazodone, Nelfinavir, Neratinib, Netupitant, Nicardipine, Niguldipine, Nilotinib, Nintedanib, Nisoldipine, Nitrendipine, Norethisterone, Norgestimate, Olaparib, Omeprazole, ONT-093, Paclitaxel, Palbociclib, Paliperidone, Pantoprazole, Paroxetine, Pemigatinib, Pibrentasvir, Pimozide, Piperine, Polyethylene glycol, Polyethylene glycol 400, Ponatinib, Posaconazole, Pralsetinib, Prazosin, Primaquine, Progesterone, Promethazine, Propafenone, Protriptyline, Quercetin, Quinacrine, Quinidine, Quinine, Ranitidine, Ranolazine, Reboxetine, Regorafenib, Relugolix, Reserpine, Reversin 121, Rifamycin, Rilpivirine, Ripretinib, Ritonavir, Rolapitant, Rucaparib, Salinomycin, Saquinavir, Sarecycline, Selegiline, Selpercatinib, Sertraline, Sildenafil, Simeprevir, Simvastatin, Sirolimus, Sorafenib, Staurosporine, Sunitinib, Tacrolimus, Tamoxifen, Tariquidar, Taurocholic acid, Telaprevir, Telmisartan, Temsirolimus, Tenofovir disoproxil, Tepotinib, Terazosin, Terfenadine, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Tetrandrine, Tezacaftor, Ticagrelor, Tipifarnib, Tipranavir, Tolvaptan, Trifluoperazine, Triflupromazine, Troleandomycin, Umbralisib, Upadacitinib, Valinomycin, Valspodar, Vandetanib, Vardenafil, Velpatasvir, Vemurafenib, Venetoclax, Venlafaxine, Verapamil, Vinblastine, Vincristine, Voacamine, Voclosporin, Voxilaprevir, Zimelidine, Zonisamide, Zosuquidar
3	P-glycoprotein 1 substrates	Abemaciclib, Acebutolol, Acenocoumarol, Acetaminophen, Acetylsalicylic acid, Afatinib, Albendazole, Aldosterone, Alfuzosin, Aliskiren, Alitretinoin, alpha-Tocopherol acetate, Ambrisentan, Amitriptyline, Amlodipine, Amprenavir, Anastrozole, Apixaban, Apremilast, Artesunate, Asunaprevir, Atazanavir, Atorvastatin, Avanafil, Avatrombopag, Axitinib, Azathioprine, Azithromycin, Baricitinib, Beclomethasone dipropionate, Belantamab mafodotin, Belinostat, Berotralstat, Betamethasone, Betamethasone phosphate, Betrixaban, Bisoprolol, Bortezomib, Bosutinib, Bromocriptine, Budesonide, Cabazitaxel, Cabergoline, Cabotegravir, Camptothecin, Canagliflozin, Capmatinib, Carfilzomib, Celecoxib, Ceritinib, Cerivastatin, Cethromycin, Cetirizine, Chloramphenicol succinate, Chloroquine, Chlorpromazine, Cimetidine, Ciprofloxacin, Citalopram, Clarithromycin, Clindamycin, Clobazam, Clofazimine, Clomifene, Clopidogrel, Clozapine, Cobimetinib, Colchicine, Conjugated estrogens, Copanlisib, Cortisone acetate, Crizotinib, Cyclosporine, Dabigatran etexilate, Dabrafenib, Daclatasvir, Dacomitinib, Dactinomycin, Dapagliflozin, Darolutamide, Darunavir, Dasabuvir, Dasatinib, Daunorubicin, Debrisoquine, Dexamethasone, Dexamethasone acetate, Diazepam, Diethylstilbestrol, Digitoxin, Digoxin, Diltiazem, Dipyridamole, Docetaxel, Dolutegravir, Domperidone, Doxepin, Doxorubicin, Duvelisib, Edoxaban, Elagolix, Elbasvir, Eletriptan, Elexacaftor, Eliglustat, Empagliflozin, Enasidenib, Enfortumab vedotin, Entrectinib, Epinastine, Erdafitinib, Erlotinib, Ertugliflozin, Erythromycin, Escitalopram, Esomeprazole, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estriol, Estrone, Ethinylestradiol, Etoposide, Everolimus, Ezetimibe, Fedratinib, Fesoterodine, Fexofenadine, Fidaxomicin, Filgotinib, Flecainide, Fluticasone, Fluticasone furoate, Fluticasone propionate, Fostemsavir, Gefitinib, Gemcitabine, Gilteritinib, Glasdegib, Glecaprevir, Gramicidin D, Grapiprant, Grazoprevir, Grepafloxacin, Haloperidol, Hydrocortisone, Hydroxyzine, Ibuprofen, Idelalisib, Imatinib, Imipramine, Indacaterol, Indinavir, Indomethacin, Inotuzumab ozogamicin, Irinotecan, Ivermectin, Ivosidenib, Ixabepilone, Ketazolam, Lamivudine, Lamotrigine, Lansoprazole, Larotrectinib, Lasmiditan, Ledipasvir, Lefamulin, Lemborexant, Lenalidomide, Lenvatinib, Letermovir, Letrozole, Levamlodipine, Levetiracetam, Levofloxacin, Levomilnacipran, Linagliptin, Lonafarnib, Loperamide, Loratadine, Losartan, Lurbinectedin, Lusutrombopag, Medrysone, Mefloquine, Meperidine, Methotrexate, Methylene blue, Methylprednisolone, Metoclopramide, Mibefradil, Mirabegron, Mitoxantrone, Monensin, Morphine, Mycophenolate mofetil, Nadolol, Naloxone, Nelfinavir, Nicardipine, Nifedipine, Nilotinib, Nintedanib, Nitrofurantoin, Nizatidine, Nortriptyline, Octreotide, Odanacatib, Olanzapine, Olaparib, Olopatadine, Omadacycline, Ombitasvir, Omeprazole, Opicapone, Osimertinib, Oxcarbazepine, Ozanimod, Paclitaxel, Palbociclib, Paliperidone, Panobinostat, Pantoprazole, Paritaprevir, Pazopanib, Pemigatinib, Pentazocine, Phenobarbital, Phenytoin, Pibrentasvir, Pitavastatin, Platelet Activating Factor, Pomalidomide, Ponatinib, Posaconazole, Pralsetinib, Pravastatin, Prazosin, Prednisolone, Prednisolone acetate, Prednisolone phosphate, Prednisone, Progesterone, Propranolol, Prucalopride, Quetiapine, Quinidine, Quinine, Raloxifene, Ranitidine, Ranolazine, Regorafenib, Relugolix, Remdesivir, Reserpine, Revefenacin, Rhodamine 6G, Rifamycin, Rimegepant, Ripretinib, Risdiplam, Risperidone, Ritonavir, Rivaroxaban, Romidepsin, Rucaparib, Saquinavir, Selexipag, Selpercatinib, Selumetinib, Sildenafil, Silodosin, Simeprevir, Sitagliptin, Sofosbuvir, Somatostatin, Somatotropin, Sorafenib, Sparfloxacin, Sphingosine, Stanolone, Stanolone acetate, Sulpiride, Sumatriptan, Tacrine, Tacrolimus, Talazoparib, Talinolol, Tamoxifen, Taurocholic acid, Tazemetostat, Technetium Tc-99m sestamibi, Tegaserod, Telaprevir, Temozolomide, Temsirolimus, Tenofovir, Tenofovir alafenamide, Tenofovir disoproxil, Tepotinib, Testosterone propionate, Tezacaftor, Ticagrelor, Timolol, Tipranavir, Tolvaptan, Topiramate, Topotecan, Toremifene, Trastuzumab deruxtecan, Trastuzumab emtansine, Trilaciclib, Trimethoprim, Trimipramine, Tucatinib, Ubidecarenone, Ubrogepant, Umeclidinium, Upadacitinib, Valinomycin, Vardenafil, Vecuronium, Velpatasvir, Vemurafenib, Venetoclax, Venlafaxine, Verapamil, Vericiguat, Vibegron, Vinblastine, Vincristine, Vinflunine, Vismodegib, Voclosporin, Voxilaprevir, Zanubrutinib, Zidovudine
4	P-glycoprotein 1 modulators	Acetylsalicylic acid, Avapritinib, Prazosin
5	P-glycoprotein 1 transporters	Ledipasvir, Tocopherol
6	P-glycoprotein 1 binders	Technetium Tc-99m tetrofosmin
7	P-glycoprotein 1 antagonists	Tocofersolan

	Interacting Group	Interacting Drugs
	Clotrimazole is a Bile salt export pump substrate
1	Bile salt export pump inhibitors	Amiodarone, Bosentan, Celecoxib, Chlorpromazine, Cholic Acid, Cimetidine, Cyclosporine, Erythromycin, Ethinylestradiol, Fusidic acid, Glyburide, Glycochenodeoxycholic Acid, Ketoconazole, Lenvatinib, Letermovir, Lopinavir, Nifedipine, Obeticholic acid, Olmesartan, Paclitaxel, Pralsetinib, Progesterone, Quinidine, Remdesivir, Reserpine, Rifampicin, Ritonavir, Simeprevir, Sulfamethoxazole, Tamoxifen, Tipranavir, Troglitazone, Ursodeoxycholic acid, Valinomycin, Vinblastine
2	Bile salt export pump substrates	Amiodarone, Astemizole, Atazanavir, Atenolol, Atorvastatin, Atropine, Belantamab mafodotin, Benzbromarone, Budesonide, Cefaclor, Cerivastatin, Cholic Acid, Clarithromycin, Cyclosporine, Daunorubicin, Diclofenac, Diethylstilbestrol, Digoxin, Dihydroergocristine, Dipyridamole, Disulfiram, Doxorubicin, Efavirenz, Erythromycin, Ezetimibe, Felodipine, Fenofibrate, Flucloxacillin, Fluorescein, Fluvoxamine, Glimepiride, Glipizide, Glyburide, Glycochenodeoxycholic Acid, Glycyrrhizic acid, Imatinib, Indinavir, Indocyanine green acid form, Indomethacin, Isradipine, Loratadine, Losartan, Lovastatin, Mifepristone, Naproxen, Nefazodone, Nelfinavir, Nicardipine, Nitrendipine, Nitrofurantoin, Ofloxacin, Paclitaxel, Pilsicainide, Pitavastatin, Prasterone sulfate, Pravastatin, Ranolazine, Repaglinide, Rosiglitazone, Rosuvastatin, Saquinavir, Simvastatin, Spironolactone, Sulfinpyrazone, Taurocholic acid, Telmisartan, Terfenadine, Tinidazole, Tipranavir, Ursodeoxycholic acid, Vinblastine, Vincristine
3	Bile salt export pump inducers	Cholic Acid, Deoxycholic acid, Dexamethasone, Dexamethasone acetate, Obeticholic acid, Phenobarbital, Taurocholic acid, Ursodeoxycholic acid

	Interacting Group	Interacting Drugs
	Clotrimazole is a Bile salt export pump inhibitor
1	Bile salt export pump inhibitors	Amiodarone, Bosentan, Celecoxib, Chlorpromazine, Cholic Acid, Cimetidine, Cyclosporine, Erythromycin, Ethinylestradiol, Fusidic acid, Glyburide, Glycochenodeoxycholic Acid, Ketoconazole, Lenvatinib, Letermovir, Lopinavir, Nifedipine, Obeticholic acid, Olmesartan, Paclitaxel, Pralsetinib, Progesterone, Quinidine, Remdesivir, Reserpine, Rifampicin, Ritonavir, Simeprevir, Sulfamethoxazole, Tamoxifen, Tipranavir, Troglitazone, Ursodeoxycholic acid, Valinomycin, Vinblastine
2	Bile salt export pump substrates	Amiodarone, Astemizole, Atazanavir, Atenolol, Atorvastatin, Atropine, Belantamab mafodotin, Benzbromarone, Budesonide, Cefaclor, Cerivastatin, Cholic Acid, Clarithromycin, Cyclosporine, Daunorubicin, Diclofenac, Diethylstilbestrol, Digoxin, Dihydroergocristine, Dipyridamole, Disulfiram, Doxorubicin, Efavirenz, Erythromycin, Ezetimibe, Felodipine, Fenofibrate, Flucloxacillin, Fluorescein, Fluvoxamine, Glimepiride, Glipizide, Glyburide, Glycochenodeoxycholic Acid, Glycyrrhizic acid, Imatinib, Indinavir, Indocyanine green acid form, Indomethacin, Isradipine, Loratadine, Losartan, Lovastatin, Mifepristone, Naproxen, Nefazodone, Nelfinavir, Nicardipine, Nitrendipine, Nitrofurantoin, Ofloxacin, Paclitaxel, Pilsicainide, Pitavastatin, Prasterone sulfate, Pravastatin, Ranolazine, Repaglinide, Rosiglitazone, Rosuvastatin, Saquinavir, Simvastatin, Spironolactone, Sulfinpyrazone, Taurocholic acid, Telmisartan, Terfenadine, Tinidazole, Tipranavir, Ursodeoxycholic acid, Vinblastine, Vincristine
3	Bile salt export pump inducers	Cholic Acid, Deoxycholic acid, Dexamethasone, Dexamethasone acetate, Obeticholic acid, Phenobarbital, Taurocholic acid, Ursodeoxycholic acid

	Interacting Group	Interacting Drugs
	Clotrimazole is a Solute carrier organic anion transporter family member 1B1 substrate
1	Solute carrier organic anion transporter family member 1B1 substrates	Ambrisentan, Asunaprevir, Atorvastatin, Axitinib, Belantamab mafodotin, Benzylpenicillin, Cerivastatin, Cholecystokinin, Cholic Acid, Cobimetinib, Conjugated estrogens, Cyclosporine, Digoxin, Dinoprostone, Elagolix, Eluxadoline, Empagliflozin, Erythromycin, Ezetimibe, Fexofenadine, Fimasartan, Fluvastatin, Gadoxetic acid, Gimatecan, Glecaprevir, Grazoprevir, Letermovir, Levomenol, Levosalbutamol, Liothyronine, Liotrix, Lovastatin, Methotrexate, Mycophenolate mofetil, Olmesartan, Ouabain, Paritaprevir, Penicillamine, Pitavastatin, Prasterone, Pravastatin, Raloxifene, Remdesivir, Repaglinide, Revefenacin, Rosuvastatin, Selexipag, Simeprevir, Simvastatin, Sumatriptan, Taurocholic acid, Technetium Tc-99m mebrofenin, Tenofovir alafenamide, Torasemide, Ubrogepant, Valsartan, Voxilaprevir
2	Solute carrier organic anion transporter family member 1B1 inhibitors	Acetylcysteine, Aminohippuric acid, Amprenavir, Artesunate, Asunaprevir, Atazanavir, Atorvastatin, Axitinib, Beclomethasone dipropionate, Bempedoic acid, Benzbromarone, Bezafibrate, Cabazitaxel, Candesartan, Caspofungin, Cerivastatin, Cholecystokinin, Cholic Acid, Clarithromycin, Cobicistat, Conjugated estrogens, Cyclosporine, Dabrafenib, Daclatasvir, Darolutamide, Darunavir, Diclofenac, Diethylstilbestrol, Digoxin, Dipyridamole, Dovitinib, Dronedarone, Elexacaftor, Eltrombopag, Eluxadoline, Enasidenib, Erythromycin, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estrone, Everolimus, Fedratinib, Fluticasone, Fluticasone furoate, Fluticasone propionate, Fluvastatin, Fostemsavir, Gemfibrozil, Genistein, Glecaprevir, Hyperforin, Idelalisib, Indinavir, Indomethacin, Irinotecan, Istradefylline, Ivermectin, Ketoconazole, Lenvatinib, Levocarnitine, Levothyroxine, Lobeglitazone, Lonafarnib, Lopinavir, Lovastatin, Lurbinectedin, Mifepristone, Nelfinavir, Nicardipine, Nifedipine, Nilotinib, Novobiocin, Nystatin, Opicapone, Osilodrostat, Ouabain, Paritaprevir, Pazopanib, Pexidartinib, Pibrentasvir, Pioglitazone, Pitavastatin, Posizolid, Pralsetinib, Progesterone, Quercetin, Quinidine, Quinine, Remdesivir, Reserpine, Rifampicin, Rifamycin, Rilpivirine, Rimegepant, Ritonavir, Rosiglitazone, Rosuvastatin, Rucaparib, Sacubitril, Saquinavir, Sildenafil, Silibinin, Simeprevir, Simvastatin, Sirolimus, Sorafenib, Sulfasalazine, Tacrolimus, Taurocholic acid, Telaprevir, Telithromycin, Teriflunomide, Tipranavir, Tirbanibulin, Troglitazone, Ubrogepant, Upadacitinib, Valsartan, Valspodar, Velpatasvir, Venetoclax, Verapamil, Vinblastine, Vincristine, Voxilaprevir
3	Solute carrier organic anion transporter family member 1B1 inducers	Apalutamide, Cholic Acid, Taurocholic acid
4	Solute carrier organic anion transporter family member 1B1 weak inhibitors	Cobimetinib
5	Solute carrier organic anion transporter family member 1B1 transporters	Velpatasvir

	Interacting Group	Interacting Drugs
	Clotrimazole is a Solute carrier organic anion transporter family member 1B1 inhibitor
1	Solute carrier organic anion transporter family member 1B1 substrates	Ambrisentan, Asunaprevir, Atorvastatin, Axitinib, Belantamab mafodotin, Benzylpenicillin, Cerivastatin, Cholecystokinin, Cholic Acid, Cobimetinib, Conjugated estrogens, Cyclosporine, Digoxin, Dinoprostone, Elagolix, Eluxadoline, Empagliflozin, Erythromycin, Ezetimibe, Fexofenadine, Fimasartan, Fluvastatin, Gadoxetic acid, Gimatecan, Glecaprevir, Grazoprevir, Letermovir, Levomenol, Levosalbutamol, Liothyronine, Liotrix, Lovastatin, Methotrexate, Mycophenolate mofetil, Olmesartan, Ouabain, Paritaprevir, Penicillamine, Pitavastatin, Prasterone, Pravastatin, Raloxifene, Remdesivir, Repaglinide, Revefenacin, Rosuvastatin, Selexipag, Simeprevir, Simvastatin, Sumatriptan, Taurocholic acid, Technetium Tc-99m mebrofenin, Tenofovir alafenamide, Torasemide, Ubrogepant, Valsartan, Voxilaprevir
2	Solute carrier organic anion transporter family member 1B1 inhibitors	Acetylcysteine, Aminohippuric acid, Amprenavir, Artesunate, Asunaprevir, Atazanavir, Atorvastatin, Axitinib, Beclomethasone dipropionate, Bempedoic acid, Benzbromarone, Bezafibrate, Cabazitaxel, Candesartan, Caspofungin, Cerivastatin, Cholecystokinin, Cholic Acid, Clarithromycin, Cobicistat, Conjugated estrogens, Cyclosporine, Dabrafenib, Daclatasvir, Darolutamide, Darunavir, Diclofenac, Diethylstilbestrol, Digoxin, Dipyridamole, Dovitinib, Dronedarone, Elexacaftor, Eltrombopag, Eluxadoline, Enasidenib, Erythromycin, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estrone, Everolimus, Fedratinib, Fluticasone, Fluticasone furoate, Fluticasone propionate, Fluvastatin, Fostemsavir, Gemfibrozil, Genistein, Glecaprevir, Hyperforin, Idelalisib, Indinavir, Indomethacin, Irinotecan, Istradefylline, Ivermectin, Ketoconazole, Lenvatinib, Levocarnitine, Levothyroxine, Lobeglitazone, Lonafarnib, Lopinavir, Lovastatin, Lurbinectedin, Mifepristone, Nelfinavir, Nicardipine, Nifedipine, Nilotinib, Novobiocin, Nystatin, Opicapone, Osilodrostat, Ouabain, Paritaprevir, Pazopanib, Pexidartinib, Pibrentasvir, Pioglitazone, Pitavastatin, Posizolid, Pralsetinib, Progesterone, Quercetin, Quinidine, Quinine, Remdesivir, Reserpine, Rifampicin, Rifamycin, Rilpivirine, Rimegepant, Ritonavir, Rosiglitazone, Rosuvastatin, Rucaparib, Sacubitril, Saquinavir, Sildenafil, Silibinin, Simeprevir, Simvastatin, Sirolimus, Sorafenib, Sulfasalazine, Tacrolimus, Taurocholic acid, Telaprevir, Telithromycin, Teriflunomide, Tipranavir, Tirbanibulin, Troglitazone, Ubrogepant, Upadacitinib, Valsartan, Valspodar, Velpatasvir, Venetoclax, Verapamil, Vinblastine, Vincristine, Voxilaprevir
3	Solute carrier organic anion transporter family member 1B1 inducers	Apalutamide, Cholic Acid, Taurocholic acid
4	Solute carrier organic anion transporter family member 1B1 weak inhibitors	Cobimetinib
5	Solute carrier organic anion transporter family member 1B1 transporters	Velpatasvir

	Interacting Group	Interacting Drugs
	Clotrimazole is a Solute carrier organic anion transporter family member 1B3 inducer
1	Solute carrier organic anion transporter family member 1B3 substrates	Ambrisentan, Atorvastatin, Belantamab mafodotin, Bempedoic acid, Caspofungin, Cholecystokinin, Cholic Acid, Cobimetinib, Conjugated estrogens, Docetaxel, Empagliflozin, Erythromycin, Fexofenadine, Fluvastatin, Gadoxetic acid, Glecaprevir, Grazoprevir, Letermovir, Levomenol, Levosalbutamol, Liothyronine, Liotrix, Methotrexate, Mycophenolate mofetil, Olmesartan, Opicapone, Ouabain, Paclitaxel, Parachlorophenol, Paritaprevir, Pitavastatin, Prasterone, Pravastatin, Raloxifene, Revefenacin, Rifampicin, Romidepsin, Selexipag, Simeprevir, Sincalide, Taurocholic acid, Technetium Tc-99m mebrofenin, Tenofovir alafenamide, Testosterone, Trastuzumab deruxtecan, Ubrogepant, Valsartan, Voxilaprevir
2	Solute carrier organic anion transporter family member 1B3 inhibitors	Asunaprevir, Ataluren, Atazanavir, Baricitinib, Beclomethasone dipropionate, Bempedoic acid, Bortezomib, Cabazitaxel, Clarithromycin, Cobicistat, Cobimetinib, Cyclosporine, Dabrafenib, Daclatasvir, Darolutamide, Dipyridamole, Dovitinib, Dronedarone, Elexacaftor, Enasidenib, Erythromycin, Everolimus, Fedratinib, Fostemsavir, Gemfibrozil, Ginsenoside Rb1, Glecaprevir, Idelalisib, Istradefylline, Ivermectin, Lenvatinib, Levothyroxine, Lonafarnib, Lopinavir, Lurbinectedin, Mifepristone, Nefazodone, Nelfinavir, Novobiocin, Nystatin, Paritaprevir, Pexidartinib, Pibrentasvir, Pioglitazone, Pralsetinib, Remdesivir, Rifampicin, Rifamycin, Rilpivirine, Rimegepant, Ritonavir, Rucaparib, Sacubitril, Selinexor, Silibinin, Simeprevir, Sulfasalazine, Telithromycin, Tipranavir, Tirbanibulin, Ubrogepant, Valspodar, Velpatasvir, Vincristine, Voxilaprevir
3	Solute carrier organic anion transporter family member 1B3 transporters	Velpatasvir
4	Solute carrier organic anion transporter family member 1B3 inducers	Progesterone