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Showing drug card for Calcium Gluceptate (DB00326)

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for All Approved Biotech Experimental Illicit Nutraceutical Small Molecule Withdrawn drugs

Version	2.5
Creation Date	2005-06-13 13:24:05
Update Date	2009-04-16 16:47:37
Primary Accession Number	DB00326
Secondary Accession Number	APRD00841
Name	Calcium Gluceptate
Drug Type	Approved Small Molecule
Description	Calcium supplements such as calcium gluceptate are taken by individuals who are unable to get enough calcium in their regular diet or who have a need for more calcium. They are used to prevent or treat several conditions that may cause hypocalcemia (not enough calcium in the blood). The body needs calcium to make strong bones. Calcium is also needed for the heart, muscles, and nervous system to work properly.
Synonyms	Calcium glucoheptonate Trimethylene chlorobromide
Brand Names	Calcium Stanley
Brand Mixtures	Not Available
Chemical IUPAC Name	calcium (3R,4S,5R,6R)-2,3,4,5,6,7-hexahydroxyheptanoate
Chemical Formula	C14H26CaO16
Chemical Structure
CAS Registry Number	29039-00-7
InChI Identifier	InChI=1/2C7H14O8.Ca/c2*8-1-2(9)3(10)4(11)5(12)6(13)7(14)15;/h2*2-6,8-13H,1H2,(H,14,15);/q;;+2/p-2/t2*2-,3-,4+,5-,6?;/m11./s1/f2C7H13O8.Ca/q2*-1;m
InChI Key	FATUQANACHZLRT-NQHXVGKMDC
KEGG Drug	D00934
KEGG Compound	Not Available
PubChem Compound	62859
PubChem Substance	205041
ChEBI ID	Not Available
PharmGKB ID	PA448734
HET ID	Not Available
GenBank ID	Not Available
Drug ID Number [DIN]	Not Available
RxList Link	Not Available
PDRhealth Link	Not Available
Wikipedia Link	Not Available
FDA Label	Not Available
Material Safety Data Sheet (MSDS)	Show PDF
Synthesis Reference	Not Available
Average Molecular Weight	490.4250
Monoisotopic Molecular Weight	490.0847
State	Solid
Melting Point	Not Available
Experimental Water Solubility	Soluble Source: PhysProp
Predicted Water Solubility	3.98e+01 mg/mL Calculated using ALOGPS
Experimental LogP/Hydrophobicity	Not Available Source: PhysProp
Predicted LogP	-1.91 Calculated using ALOGPS
Experimental LogS	Not Available
Predicted LogS	-1.09 Calculated using ALOGPS
Experimental Caco2 Permeability	Not Available
pKa/Isoelectric Point	Not Available
Mass Spectrum	Not Available
MOL File	Show | Download
SDF File	Show | Download
PDB File	Show | Download
2D Structure
3D Structure
Experimental PDB ID	Not Available
Isomeric SMILES	[Ca++].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@@H](O)C([O-])=O
Canonical SMILES	[Ca++].OCC(O)C(O)C(O)C(O)C(O)C([O-])=O.OCC(O)C(O)C(O)C(O)C(O)C([O-])=O
Drug Category	Antihypermagnesemic Agents Antihypocalcemic Agents Electrolyte replenisher Nutritional supplement, mineral
ATC Codes	Not Available
AHFS Codes	Not Available
Indication	For treatment of mild hypocalcemia due to neonatal tetany, tetany due to parathyroid deficiency or vitamin D deficiency, and alkalosis, as prophylaxis of hypocalcemia during exchange transfusions, in the treatment of intestinal malabsorption, and to replenish electrolytes.
Pharmacology	Calcium supplements such as calcium gluceptate are taken by individuals who are unable to get enough calcium in their regular diet or who have a need for more calcium. They are used to prevent or treat several conditions that may cause hypocalcemia (not enough calcium in the blood). The body needs calcium to make strong bones. Calcium is also needed for the heart, muscles, and nervous system to work properly. The bones serve as a storage site for the body's calcium. They are continuously giving up calcium to the bloodstream and then replacing it as the body's need for calcium changes from day to day. When there is not enough calcium in the blood to be used by the heart and other organs, your body will take the needed calcium from the bones. When you eat foods rich in calcium, the calcium will be restored to the bones and the balance between your blood and bones will be maintained.
Mechanism of Action	Calcium gluceptate replenishes the deminished levels of calcium in the body, returning them to normal levels.
Absorption	Rapidly absorbed following oral administration.
Toxicity	Symptoms of overdose include confusion, drowsiness (severe), high blood pressure, increased sensitivity of eyes or skin to light, irregular, fast, or slow heartbeat, and unusually large amount of urine or increased frequency of urination.
Protein Binding	Not Available
Biotransformation	Not Available
Half Life	Not Available
Dosage Forms	Form Route Solution Intravenous Solution Oral
Patient Information	Show
Contraindications	Not Available
Interactions	Show
Drug Interactions	Not Available
Food Interactions	Not Available
Pathways	Not Available
General References	Drugs.com
Organisms Affected	Humans and other mammals

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