Drugbank Logo

Showing drug card for Calcium Gluceptate (DB00326)

Legend: drug field target field enzyme field

Version 2.5
Creation Date 2005-06-13 13:24:05
Update Date 2009-04-16 16:47:37
Primary Accession Number DB00326
Secondary Accession Number
  • APRD00841
Name Calcium Gluceptate
Drug Type
  • Approved
  • Small Molecule
Description Calcium supplements such as calcium gluceptate are taken by individuals who are unable to get enough calcium in their regular diet or who have a need for more calcium. They are used to prevent or treat several conditions that may cause hypocalcemia (not enough calcium in the blood). The body needs calcium to make strong bones. Calcium is also needed for the heart, muscles, and nervous system to work properly.
Synonyms
  1. Calcium glucoheptonate
  2. Trimethylene chlorobromide
Brand Names
  1. Calcium Stanley
Brand Mixtures Not Available
Chemical IUPAC Name calcium (3R,4S,5R,6R)-2,3,4,5,6,7-hexahydroxyheptanoate
Chemical Formula C14H26CaO16
Chemical Structure Structure
CAS Registry Number 29039-00-7
InChI Identifier InChI=1/2C7H14O8.Ca/c2*8-1-2(9)3(10)4(11)5(12)6(13)7(14)15;/h2*2-6,8-13H,1H2,(H,14,15);/q;;+2/p-2/t2*2-,3-,4+,5-,6?;/m11./s1/f2C7H13O8.Ca/q2*-1;m
InChI Key FATUQANACHZLRT-NQHXVGKMDC
KEGG Drug D00934 Link Image
KEGG Compound Not Available
PubChem Compound 62859 Link Image
PubChem Substance 205041 Link Image
ChEBI ID Not Available
PharmGKB ID PA448734 Link Image
HET ID Not Available
GenBank ID Not Available
Drug ID Number [DIN] Not Available
RxList Link Not Available
PDRhealth Link Not Available
Wikipedia Link Not Available
FDA Label Not Available
Material Safety Data Sheet (MSDS)
Synthesis Reference Not Available
Average Molecular Weight 490.4250
Monoisotopic Molecular Weight 490.0847
State Solid
Melting Point Not Available
Experimental Water Solubility Soluble Source: PhysProp
Predicted Water Solubility 3.98e+01 mg/mL Calculated using ALOGPS
Experimental LogP/Hydrophobicity Not Available Source: PhysProp
Predicted LogP -1.91 Calculated using ALOGPS
Experimental LogS Not Available
Predicted LogS -1.09 Calculated using ALOGPS
Experimental Caco2 Permeability Not Available
pKa/Isoelectric Point Not Available
Mass Spectrum Not Available
MOL File Show Link Image | Download Link Image
SDF File Show Link Image | Download Link Image
PDB File Show Link Image | Download Link Image
2D Structure
3D Structure
Experimental PDB ID Not Available
Isomeric SMILES [Ca++].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@@H](O)C([O-])=O
Canonical SMILES [Ca++].OCC(O)C(O)C(O)C(O)C(O)C([O-])=O.OCC(O)C(O)C(O)C(O)C(O)C([O-])=O
Drug Category
  • Antihypermagnesemic Agents
  • Antihypocalcemic Agents
  • Electrolyte replenisher
  • Nutritional supplement, mineral
ATC Codes Not Available
AHFS Codes Not Available
Indication For treatment of mild hypocalcemia due to neonatal tetany, tetany due to parathyroid deficiency or vitamin D deficiency, and alkalosis, as prophylaxis of hypocalcemia during exchange transfusions, in the treatment of intestinal malabsorption, and to replenish electrolytes.
Pharmacology Calcium supplements such as calcium gluceptate are taken by individuals who are unable to get enough calcium in their regular diet or who have a need for more calcium. They are used to prevent or treat several conditions that may cause hypocalcemia (not enough calcium in the blood). The body needs calcium to make strong bones. Calcium is also needed for the heart, muscles, and nervous system to work properly. The bones serve as a storage site for the body's calcium. They are continuously giving up calcium to the bloodstream and then replacing it as the body's need for calcium changes from day to day. When there is not enough calcium in the blood to be used by the heart and other organs, your body will take the needed calcium from the bones. When you eat foods rich in calcium, the calcium will be restored to the bones and the balance between your blood and bones will be maintained.
Mechanism of Action Calcium gluceptate replenishes the deminished levels of calcium in the body, returning them to normal levels.
Absorption Rapidly absorbed following oral administration.
Toxicity Symptoms of overdose include confusion, drowsiness (severe), high blood pressure, increased sensitivity of eyes or skin to light, irregular, fast, or slow heartbeat, and unusually large amount of urine or increased frequency of urination.
Protein Binding Not Available
Biotransformation Not Available
Half Life Not Available
Dosage Forms
Form Route
Solution Intravenous
Solution Oral
Patient Information Show Link Image
Contraindications Not Available
Interactions Show Link Image
Drug Interactions Not Available
Food Interactions Not Available
Pathways Not Available
General References
  1. Drugs.com Link Image
Organisms Affected
  • Humans and other mammals

This project is supported by Genome Alberta & Genome Canada, a not-for-profit organization that is leading Canada's national genomics strategy with $600 million in funding from the federal government. This project is also supported in part by GenomeQuest, Inc., an enterprise genomic information company serving the life science community.