Showing BioInteractions for Meprobamate (DB00371)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
Interacting GroupInteracting Drugs
Meprobamate is a Gamma-aminobutyric acid receptor subunit alpha-1 agonist
1Gamma-aminobutyric acid receptor subunit alpha-1 potentiatorsAmobarbital, Aprobarbital, Barbital, Butalbital, Butobarbital, Dihydro-2-thioxo-5-((5-(2-(trifluoromethyl)phenyl)-2-furanyl)methyl)-4,6(1H,5H)-pyrimidinedione, Dihydroquinidine barbiturate, Eszopiclone, Fludiazepam, Heptabarbital, Hexobarbital, Metharbital, Methylphenobarbital, Pentobarbital, Phenobarbital, Primidone, Quinidine barbiturate, Secobarbital, Talbutal, Thiopental, Zaleplon, Zopiclone
2Gamma-aminobutyric acid receptor subunit alpha-1 agonistsEthanol, Etomidate, Glutethimide, Isoflurane, Methoxyflurane, Methyprylon, Progabide, Sevoflurane, Thiamylal, Topiramate, Zolpidem
3Gamma-aminobutyric acid receptor subunit alpha-1 antagonistsAmoxapine, Flumazenil, Methohexital, Picrotoxin
4Gamma-aminobutyric acid receptor subunit alpha-1 negative modulatorsGinkgo biloba
5Gamma-aminobutyric acid receptor subunit alpha-1 activatorsCarisoprodol
6Gamma-aminobutyric acid receptor subunit alpha-1 modulatorsCarisoprodol
Interacting GroupInteracting Drugs
Meprobamate is a Gamma-aminobutyric acid receptor subunit alpha-2 agonist
1Gamma-aminobutyric acid receptor subunit alpha-2 potentiatorsAmobarbital, Aprobarbital, Barbital, Butalbital, Butobarbital, Dihydro-2-thioxo-5-((5-(2-(trifluoromethyl)phenyl)-2-furanyl)methyl)-4,6(1H,5H)-pyrimidinedione, Fludiazepam, Heptabarbital, Hexobarbital, Metharbital, Methylphenobarbital, Pentobarbital, Primidone, Quinidine barbiturate, Secobarbital, Talbutal, Thiopental, Zopiclone
2Gamma-aminobutyric acid receptor subunit alpha-2 agonistsEszopiclone, Zolpidem
3Gamma-aminobutyric acid receptor subunit alpha-2 positive allosteric modulatorsAZD-7325
Interacting GroupInteracting Drugs
Meprobamate is a Gamma-aminobutyric acid receptor subunit alpha-3 agonist
1Gamma-aminobutyric acid receptor subunit alpha-3 agonistsEszopiclone, Zolpidem
2Gamma-aminobutyric acid receptor subunit alpha-3 potentiatorsAmobarbital, Aprobarbital, Barbital, Butalbital, Butobarbital, Dihydro-2-thioxo-5-((5-(2-(trifluoromethyl)phenyl)-2-furanyl)methyl)-4,6(1H,5H)-pyrimidinedione, Fludiazepam, Heptabarbital, Hexobarbital, Metharbital, Methylphenobarbital, Pentobarbital, Primidone, Secobarbital, Talbutal, Thiopental, Zopiclone
3Gamma-aminobutyric acid receptor subunit alpha-3 positive allosteric modulatorsAZD-7325
4Gamma-aminobutyric acid receptor subunit alpha-3 modulatorsCarisoprodol
Interacting GroupInteracting Drugs
Meprobamate is a Gamma-aminobutyric acid receptor subunit alpha-4 agonist
1Gamma-aminobutyric acid receptor subunit alpha-4 potentiatorsAmobarbital, Aprobarbital, Barbital, Butalbital, Butobarbital, Dihydro-2-thioxo-5-((5-(2-(trifluoromethyl)phenyl)-2-furanyl)methyl)-4,6(1H,5H)-pyrimidinedione, Heptabarbital, Hexobarbital, Metharbital, Methylphenobarbital, Pentobarbital, Primidone, Secobarbital, Talbutal, Thiopental
Interacting GroupInteracting Drugs
Meprobamate is a Gamma-aminobutyric acid receptor subunit alpha-5 agonist
1Gamma-aminobutyric acid receptor subunit alpha-5 agonistsEszopiclone
2Gamma-aminobutyric acid receptor subunit alpha-5 potentiatorsAmobarbital, Aprobarbital, Barbital, Butalbital, Butobarbital, Dihydro-2-thioxo-5-((5-(2-(trifluoromethyl)phenyl)-2-furanyl)methyl)-4,6(1H,5H)-pyrimidinedione, Fludiazepam, Heptabarbital, Hexobarbital, Metharbital, Methylphenobarbital, Pentobarbital, Primidone, Secobarbital, Talbutal, Thiopental, Zopiclone
3Gamma-aminobutyric acid receptor subunit alpha-5 antagonistsFlumazenil
4Gamma-aminobutyric acid receptor subunit alpha-5 modulatorsCarisoprodol
Interacting GroupInteracting Drugs
Meprobamate is a Gamma-aminobutyric acid receptor subunit alpha-6 agonist
1Gamma-aminobutyric acid receptor subunit alpha-6 potentiatorsAmobarbital, Aprobarbital, Barbital, Butalbital, Butobarbital, Dihydro-2-thioxo-5-((5-(2-(trifluoromethyl)phenyl)-2-furanyl)methyl)-4,6(1H,5H)-pyrimidinedione, Heptabarbital, Hexobarbital, Metharbital, Methylphenobarbital, Pentobarbital, Primidone, Secobarbital, Talbutal, Thiopental
Interacting GroupInteracting Drugs
Meprobamate is a GABA(A) Receptor positive allosteric modulator
1GABA(A) Receptor positive allosteric modulators1,2-Benzodiazepine, Adinazolam, Alprazolam, Bentazepam, Brexanolone, Bromazepam, Brotizolam, Butabarbital, Butalbital, Camazepam, Chlordiazepoxide, Cinazepam, Cinolazepam, Clobazam, Clonazepam, Clorazepic acid, Clotiazepam, Cloxazolam, Delorazepam, Desflurane, Diazepam, Doxefazepam, Estazolam, Eszopiclone, Ethchlorvynol, Ethyl loflazepate, Etizolam, Etomidate, Flumazenil, Flunitrazepam, Flurazepam, Glutethimide, Halazepam, Halothane, Isoflurane, Ketazolam, Loprazolam, Lorazepam, Lormetazepam, Medazepam, Metharbital, Methoxyflurane, Methyprylon, Mexazolam, Midazolam, Nitrazepam, Nordazepam, Oxazepam, Oxazepam acetate, Pentobarbital, Pinazepam, Prazepam, Primidone, Propofol, Quazepam, Remimazolam, Sevoflurane, Stiripentol, Talbutal, Temazepam, Triazolam
2GABA(A) Receptor potentiatorsEnflurane
3GABA(A) Receptor bindersAmoxapine, Memantine
4GABA(A) Receptor antagonistsApalutamide, Lamotrigine, Prasterone, Thiocolchicoside
5GABA(A) Receptor agonistsStiripentol, Taurine
6GABA(A) Receptor inducersLamotrigine
7GABA(A) Receptor inhibitorsMedroxyprogesterone acetate