Showing drug card for Bentoquatam (DB00516)
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| Version | 2.5 |
| Creation Date | 2005-06-13 13:24:05 |
| Update Date | 2009-06-23 18:08:13 |
| Primary Accession Number | DB00516 |
| Secondary Accession Number |
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| Name | Bentoquatam |
| Drug Type |
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| Description | Bentoquatam is a topical medication intended to act as a shield against exposure to the irritating substance urushiol, found in plants such as poison ivy or poison oak. Bentoquatam contains bentonite, a clay, and is only effective as long as the film is visible on the skin. |
| Synonyms | Not Available |
| Brand Names |
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| Brand Mixtures | Not Available |
| Chemical IUPAC Name | dioxosilane; oxo-oxoalumanyloxyalumane; hydrate |
| Chemical Formula | Al2H2O6Si |
| Chemical Structure | |
| CAS Registry Number | 1340-69-8 |
| InChI Identifier | InChI=1/2Al.O2Si.H2O.3O/c;;1-3-2;;;;/h;;;1H2;;;/rAl2O3.O2Si.H2O/c3-1-5-2-4;1-3-2;/h;;1H2 |
| InChI Key | SVPXDRXYRYOSEX-YHXBNZMQAQ |
| KEGG Drug | Not Available |
| KEGG Compound | Not Available |
| PubChem Compound | 517273  |
| PubChem Substance | 10501170 |
| ChEBI ID | Not Available |
| PharmGKB ID | PA448570 |
| HET ID | Not Available |
| GenBank ID | Not Available |
| Drug ID Number [DIN] | Not Available |
| RxList Link | Not Available |
| PDRhealth Link | Not Available |
| Wikipedia Link | http://en.wikipedia.org/wiki/Bentoquatam |
| FDA Label | Not Available |
| Material Safety Data Sheet (MSDS) | |
| Synthesis Reference | Not Available |
| Average Molecular Weight | 180.0609 |
| Monoisotopic Molecular Weight | 179.9251 |
| State | Solid |
| Melting Point | Not Available |
| Experimental Water Solubility | Soluble Source: PhysProp |
| Predicted Water Solubility | Not Available Calculated using ALOGPS |
| Experimental LogP/Hydrophobicity | Not Available Source: PhysProp |
| Predicted LogP | Not Available Calculated using ALOGPS |
| Experimental LogS | Not Available |
| Predicted LogS | Not Available Calculated using ALOGPS |
| Experimental Caco2 Permeability | Not Available |
| pKa/Isoelectric Point | Not Available |
| Mass Spectrum | Not Available |
| MOL File | Show | Download |
| SDF File | Show | Download |
| PDB File | Show | Download |
| 2D Structure | |
| 3D Structure | |
| Experimental PDB ID | Not Available |
| Isomeric SMILES | O.O=[Si]=O.O=[Al]O[Al]=O |
| Canonical SMILES | O.O=[Si]=O.O=[Al]O[Al]=O |
| Drug Category |
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| ATC Codes | Not Available |
| AHFS Codes | Not Available |
| Indication | Used to prevent or reduce the severity of allergic contact dermatitis due to urushiol, the allergenic resin of poison ivy, poison oak, and poison sumac. |
| Pharmacology | Bentoquatam protects the skin like a shield against poison ivy, poison oak, and poison sumac by physically blocking skin contact with their resin. The best protection against getting these conditions is to avoid contact with these plants. This medicine does not dry oozing and weeping caused by the rash of poison ivy, poison oak, or poison sumac. |
| Mechanism of Action | The mechanism of action is unknown. It is thought topically applied bentoquatam acts as a physical barrier that interferes with the adsorption of antigens onto the skin and reduces absorption of antigens into the skin. It probably does not work by modifying the systemic allergic response. |
| Absorption | Not Available |
| Toxicity | Rare side effects include mild erythema (mild redness of skin). |
| Protein Binding | Not Available |
| Biotransformation | Not Available |
| Half Life | Not Available |
| Dosage Forms | Not Available |
| Patient Information | Show |
| Contraindications | Show |
| Interactions | Show |
| Drug Interactions | Not Available |
| Food Interactions | Not Available |
| Pathways | Not Available |
| General References | |
| Organisms Affected |
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