Showing BioInteractions for Rocuronium (DB00728)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Rocuronium is a Neuronal acetylcholine receptor subunit alpha-2 antagonist | ||
| 1 | Neuronal acetylcholine receptor subunit alpha-2 agonists | Carbamoylcholine, Epibatidine, Nicotine |
| 2 | Neuronal acetylcholine receptor subunit alpha-2 antagonists | Atracurium besylate, Cisatracurium, Dextromethorphan, Doxacurium, Fluoxetine, Gallamine triethiodide, Hexamethonium, Mecamylamine, Metocurine, Metocurine iodide, Mivacurium, Pancuronium, Pipecuronium, Procaine, Tubocurarine, Vecuronium |
| 3 | Neuronal acetylcholine receptor subunit alpha-2 partial agonists | Decamethonium |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Rocuronium is a 5-hydroxytryptamine receptor 3A antagonist | ||
| 1 | 5-hydroxytryptamine receptor 3A antagonists | Alosetron, Amoxapine, Aripiprazole, Cannabidiol, Clozapine, Dolasetron, Granisetron, Memantine, Methadone, Metoclopramide, Olanzapine, Ondansetron, Palonosetron, Procaine, Ramosetron, Tropisetron, Tubocurarine, Vortioxetine |
| 2 | 5-hydroxytryptamine receptor 3A agonists | Cisapride |
| 3 | 5-hydroxytryptamine receptor 3A ligands | Quetiapine |
| 4 | 5-hydroxytryptamine receptor 3A binders | Loxapine, Trimipramine |
| 5 | 5-hydroxytryptamine receptor 3A inhibitors | Lamotrigine |
| 6 | 5-hydroxytryptamine receptor 3A potentiators | Ketamine |
| 7 | 5-hydroxytryptamine receptor 3A negative modulators | Bupropion |