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Identification
NameRanitidine
Accession NumberDB00863  (APRD00254)
TypeSmall Molecule
GroupsApproved
DescriptionA non-imidazole blocker of those histamine receptors that mediate gastric secretion (H2 receptors). It is used to treat gastrointestinal ulcers. [PubChem]
Structure
Thumb
Synonyms
RAN
Ranitidina
Ranitidinum
External Identifiers Not Available
Approved Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Acid Reducertablet150 mgoralPendopharm Division Of De Pharmascience IncNot applicableNot applicableCanada
Act Ranitidinetablet150 mgoralActavis Pharma Company2004-04-19Not applicableCanada
Act Ranitidinetablet300 mgoralActavis Pharma Company2004-02-19Not applicableCanada
Bci Ranitidinetablet150 mgoralBaker Cummins IncNot applicableNot applicableCanada
Bci Ranitidinetablet300 mgoralBaker Cummins IncNot applicableNot applicableCanada
Dom-ranitidinetablet300 mgoralDominion Pharmacal2001-03-22Not applicableCanada
Dom-ranitidinetablet150 mgoralDominion Pharmacal2001-03-22Not applicableCanada
Mar-ranitidinetablet300 mgoralMarcan Pharmaceuticals IncNot applicableNot applicableCanada
Mar-ranitidinetablet150 mgoralMarcan Pharmaceuticals IncNot applicableNot applicableCanada
Med Ranitidine Tablets 150mgtablet150 mgoralMedican Pharma Incorporated1999-04-062011-03-29Canada
Myl-ranitidinetablet150 mgoralMylan Pharmaceuticals Ulc2011-05-132016-06-28Canada
Myl-ranitidinetablet300 mgoralMylan Pharmaceuticals Ulc2011-05-132016-06-28Canada
Mylan-ranitidinetablet300 mgoralMylan Pharmaceuticals Ulc1996-12-31Not applicableCanada
Mylan-ranitidinetablet150 mgoralMylan Pharmaceuticals Ulc1996-12-31Not applicableCanada
Nu-ranit Tab 150mgtablet150 mgoralNu Pharm Inc1990-12-312012-09-04Canada
Nu-ranit Tab 300mgtablet300 mgoralNu Pharm Inc1990-12-312012-09-04Canada
PHL-ranitidinetablet300 mgoralPharmel Inc2002-08-27Not applicableCanada
PHL-ranitidinetablet150 mgoralPharmel Inc2002-08-27Not applicableCanada
PMS-ranitidine 150 mgtablet150 mgoralPharmascience Inc2000-08-25Not applicableCanada
PMS-ranitidine 300 mgtablet300 mgoralPharmascience Inc2000-08-25Not applicableCanada
Pyloridtablet400 mgoralGlaxo Wellcome Inc.1997-08-292000-07-27Canada
Ran-ranitidinetablet150 mgoralRanbaxy Pharmaceuticals Canada Inc.2009-11-02Not applicableCanada
Ran-ranitidinetablet300 mgoralRanbaxy Pharmaceuticals Canada Inc.2009-11-02Not applicableCanada
Ranitidinetablet300 mgoralCobalt Pharmaceuticals CompanyNot applicableNot applicableCanada
Ranitidinetablet150 mgoralSorres Pharma Inc2009-06-222014-06-20Canada
Ranitidinetablet150 mgoralSivem Pharmaceuticals Ulc2012-06-11Not applicableCanada
Ranitidinetablet300 mgoralSorres Pharma Inc2009-06-222014-06-20Canada
Ranitidinetablet300 mgoralSanis Health Inc2010-07-26Not applicableCanada
Ranitidinetablet150 mgoralMylan Pharmaceuticals Ulc2009-10-222012-10-19Canada
Ranitidinetablet150 mgoralSanis Health Inc2010-07-26Not applicableCanada
Ranitidinetablet300 mgoralSivem Pharmaceuticals Ulc2012-06-11Not applicableCanada
Ranitidinetablet150 mgoralCobalt Pharmaceuticals CompanyNot applicableNot applicableCanada
Ranitidinetablet300 mgoralMylan Pharmaceuticals Ulc2009-10-222012-10-19Canada
Ranitidine - 150tablet150 mgoralPro Doc Limitee1988-12-31Not applicableCanada
Ranitidine - 300tablet300 mgoralPro Doc Limitee1988-12-31Not applicableCanada
Ranitidine Injection USPsolution25 mgintramuscular; intravenousSandoz Canada Incorporated2004-09-16Not applicableCanada
Ranitidine Tabletstablet150 mgoralRanbaxy Pharmaceuticals Canada Inc.Not applicableNot applicableCanada
Ranitidine Tabletstablet300 mgoralRanbaxy Pharmaceuticals Canada Inc.Not applicableNot applicableCanada
Ranitidine Tablets 150mgtablet150 mgoralPrempharm Inc1997-01-032005-08-05Canada
Ranitidine Tablets 300mgtablet300 mgoralPrempharm Inc1997-01-032005-08-05Canada
Ratio-ranitidinetablet150 mgoralRatiopharm Inc Division Of Teva Canada Limited1989-12-312014-09-19Canada
Ratio-ranitidinetablet300 mgoralRatiopharm Inc Division Of Teva Canada Limited1989-12-312014-09-19Canada
Riva-ranitidine 150tablet150 mgoralLaboratoire Riva Inc2005-07-05Not applicableCanada
Riva-ranitidine 300tablet300 mgoralLaboratoire Riva Inc2005-07-11Not applicableCanada
Sandoz Ranitidinetablet150 mgoralSandoz Canada Incorporated2001-05-15Not applicableCanada
Sandoz Ranitidinetablet300 mgoralSandoz Canada Incorporated2001-05-15Not applicableCanada
Scheinpharm Ranitidine 150 mgtablet150 mgoralPharmascience Inc2000-04-252014-09-08Canada
Scheinpharm Ranitidine 300 mgtablet300 mgoralPharmascience Inc2000-04-252014-09-08Canada
Teva-ranitidinetablet150 mgoralTeva Canada Limited1989-12-31Not applicableCanada
Teva-ranitidinetablet300 mgoralTeva Canada Limited1989-12-31Not applicableCanada
Teva-ranitidine Injectionsolution25 mgintramuscular; intravenousTeva Canada LimitedNot applicableNot applicableCanada
Teva-ranitidine Solutionsolution15 mgoralTeva Canada Limited2004-09-08Not applicableCanada
Tria-ranitidine 150mg Tablettablet150 mgoralLaboratoires Trianon IncNot applicableNot applicableCanada
Tria-ranitidine 300mg Tablettablet300 mgoralLaboratoires Trianon IncNot applicableNot applicableCanada
Zantacsolution15 mgoralGlaxosmithkline Inc1998-10-272012-02-29Canada
Zantactablet, film coated150 mg/1oralGlaxo Smith Kline Llc1989-10-01Not applicableUs
Zantacinjection, solution25 mg/mLintramuscular; intravenousCovis Pharmaceuticals, Inc.2013-06-14Not applicableUs
Zantactablet150 mgoralGlaxosmithkline Inc1999-08-06Not applicableCanada
Zantactablet, film coated300 mg/1oralGlaxo Smith Kline Llc1989-10-01Not applicableUs
Zantacinjection, solution25 mg/mLintramuscular; intravenousCardinal Health1989-10-01Not applicableUs
Zantactablet300 mgoralGlaxosmithkline Inc1999-12-20Not applicableCanada
Zantacinjection, solution25 mg/mLintramuscular; intravenousCovis Pharmaceuticals, Inc.2013-03-15Not applicableUs
Zantacliquid25 mgintramuscular; intravenousGlaxo Canada Inc1984-12-312001-10-26Canada
Zantacsolution25 mgintramuscular; intravenousGlaxosmithkline Inc2000-05-01Not applicableCanada
Zantacinjection, solution25 mg/mLintramuscular; intravenousCovis Pharmaceuticals, Inc.2013-06-14Not applicableUs
Zantac Oral Solution 15mg/mlsolution15 mgoralGlaxo Canada Inc1989-12-311999-08-12Canada
Zantac Tab 150mgtablet150 mgoralGlaxo Canada Inc1982-12-312000-08-02Canada
Zantac Tab 300mgtablet300 mgoralGlaxo Canada Inc1986-12-312000-08-02Canada
Zantac-C Cap 150mgcapsule150 mgoralGlaxo Canada Inc1990-12-311998-07-30Canada
Zantac-C Cap 300mgcapsule300 mgoralGlaxo Canada Inc1990-12-311998-07-30Canada
Approved Generic Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Apo-ranitidinesolution15 mgoralApotex Inc2006-07-14Not applicableCanada
Apo-ranitidine Tablet 150mgtablet150 mgoralApotex Inc1987-12-31Not applicableCanada
Apo-ranitidine Tablet 300mgtablet300 mgoralApotex Inc1987-12-31Not applicableCanada
Good Sense Acid Reducertablet75 mg/1oralbryant ranch prepack2009-05-21Not applicableUs
Ranitidinesolution15 mg/mLoralAtlantic Biologicals Corps2010-03-12Not applicableUs
Ranitidinetablet, film coated150 mg/1oralREMEDYREPACK INC.2013-05-09Not applicableUs
Ranitidinetablet150 mg/1oralCardinal Health2009-12-16Not applicableUs
Ranitidinetablet, film coated150 mg/1oralClinical Solutions Wholesale2008-11-19Not applicableUs
Ranitidinetablet150 mg/1oralAmerican Health Packaging2014-07-07Not applicableUs
Ranitidinetablet150 mg/1oralAmerican Health Packaging2012-03-012015-12-30Us
Ranitidinetablet300 mg/1oralProficient Rx LP2009-12-16Not applicableUs
Ranitidinesolution15 mg/mLoralPharmaceutical Associates, Inc.2009-09-19Not applicableUs
Ranitidinetablet150 mg/1oralMajor Pharmaceuticals2010-07-23Not applicableUs
Ranitidinetablet150 mg/1oralRx Change Co.2014-11-25Not applicableUs
Ranitidinesolution15 mg/mLoralHi Tech Pharmacal Co., Inc.2011-03-22Not applicableUs
Ranitidinetablet, film coated300 mg/1oralPd Rx Pharmaceuticals, Inc.2009-11-06Not applicableUs
Ranitidinetablet150 mg/1oralREMEDYREPACK INC.2015-07-22Not applicableUs
Ranitidinesolution15 mg/mLoralAmneal Pharmaceuticals of New York, LLC2010-03-12Not applicableUs
Ranitidinetablet, film coated300 mg/1oralApotex Corp1997-09-13Not applicableUs
Ranitidinesyrup15 mg/mLoralWOCKHARDT USA LLC2009-05-26Not applicableUs
Ranitidinetablet300 mg/1oralLake Erie Medical DBA Quality Care Products LLC2009-12-16Not applicableUs
Ranitidinetablet300 mg/1oralAmneal Pharmaceuticals of New York, LLC2009-12-16Not applicableUs
Ranitidinetablet, film coated150 mg/1oralCardinal Health2008-11-19Not applicableUs
Ranitidinetablet150 mg/1oralWockhardt Limited1998-12-17Not applicableUs
Ranitidinetablet, film coated300 mg/1oralProficient Rx LP2008-11-19Not applicableUs
Ranitidinetablet, film coated150 mg/1oralMed Vantx, Inc.1997-09-12Not applicableUs
Ranitidinetablet300 mg/1oralPreferred Pharmaceuticals, Inc2012-02-27Not applicableUs
Ranitidinetablet150 mg/1oralLiberty Pharmaceuticals, Inc.2009-12-16Not applicableUs
Ranitidinetablet150 mg/1oralBlenheim Pharmacal, Inc.2010-10-21Not applicableUs
Ranitidinetablet300 mg/1oralSTAT Rx USA LLC1998-12-17Not applicableUs
Ranitidinetablet, film coated150 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2009-11-06Not applicableUs
Ranitidinetablet150 mg/1oralRebel Distributors2009-12-17Not applicableUs
Ranitidinetablet150 mg/1oralREMEDYREPACK INC.2010-12-06Not applicableUs
Ranitidinetablet, film coated150 mg/1oralREMEDYREPACK INC.2013-07-08Not applicableUs
Ranitidinetablet300 mg/1oralCardinal Health2009-12-16Not applicableUs
Ranitidinetablet, film coated300 mg/1oralClinical Solutions Wholesale2008-11-19Not applicableUs
Ranitidinetablet150 mg/1oralMc Kesson Packaging Services Business Unit Of Mc Kesson Corporation2004-07-01Not applicableUs
Ranitidinetablet, film coated300 mg/1oralAmerican Health Packaging2015-03-31Not applicableUs
Ranitidinesolution15 mg/mLoralPharmaceutical Associates, Inc.2009-09-19Not applicableUs
Ranitidinetablet300 mg/1oralMajor Pharmaceuticals2010-07-23Not applicableUs
Ranitidinetablet150 mg/1oralLake Erie Medical DBA Quality Care Products LLC2009-12-16Not applicableUs
Ranitidinesyrup15 mg/mLoralUnit Dose Services2013-07-15Not applicableUs
Ranitidinetablet150 mg/1oralPhysicians Total Care, Inc.1999-09-21Not applicableUs
Ranitidinetablet150 mg/1oralWockhardt Limited2009-12-11Not applicableUs
Ranitidinetablet300 mg/1oralSt Marys Medical Park Pharmacy2014-01-30Not applicableUs
Ranitidinetablet300 mg/1oralWockhardt USA LLC.2009-12-11Not applicableUs
Ranitidinetablet150 mg/1oralCarilion Materials Management2009-12-16Not applicableUs
Ranitidinesolution15 mg/mLoralSilarx Pharmaceuticals, Inc.2010-12-10Not applicableUs
Ranitidinesyrup15 mg/mLoralHeritage Pharmaceuticals Inc.2013-07-15Not applicableUs
Ranitidinetablet300 mg/1oralPar Pharmaceutical Inc1999-01-28Not applicableUs
Ranitidinetablet, film coated150 mg/1oralState of Florida DOH Central Pharmacy2009-07-01Not applicableUs
Ranitidinetablet300 mg/1oralWockhardt Limited1998-12-17Not applicableUs
Ranitidinetablet150 mg/1oralbryant ranch prepack2009-12-16Not applicableUs
Ranitidinetablet150 mg/1oralContract Pharmacy Services Pa2010-03-11Not applicableUs
Ranitidinetablet150 mg/1oralPreferred Pharmaceuticals, Inc2012-02-27Not applicableUs
Ranitidinesolution15 mg/mLoralActavis Mid Atlantic LLC2007-03-15Not applicableUs
Ranitidinetablet150 mg/1oralSTAT Rx USA LLC2009-12-16Not applicableUs
Ranitidinetablet300 mg/1oralPd Rx Pharmaceuticals, Inc.2009-12-16Not applicableUs
Ranitidinetablet150 mg/1oralNorthwind Pharmaceuticals, LLC2014-09-15Not applicableUs
Ranitidinetablet, film coated300 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2009-11-06Not applicableUs
Ranitidinetablet300 mg/1oralRebel Distributors2009-12-17Not applicableUs
Ranitidinetablet150 mg/1oralCardinal Health2010-07-23Not applicableUs
Ranitidinetablet150 mg/1oralClinical Solutions Wholesale2009-12-16Not applicableUs
Ranitidinetablet150 mg/1oralMc Kesson Packaging Services Business Unit Of Mc Kesson Corporation2012-11-06Not applicableUs
Ranitidinetablet, film coated150 mg/1oralGlenmark Generics Inc., USA2008-11-19Not applicableUs
Ranitidinetablet, film coated150 mg/1oralIVAX Pharmaceuticals, Inc.1997-09-12Not applicableUs
Ranitidinetablet150 mg/1oralBlenheim Pharmacal, Inc.2011-09-30Not applicableUs
Ranitidinetablet150 mg/1oralAv Kare, Inc.2014-08-18Not applicableUs
Ranitidinetablet, film coated150 mg/1oralUnit Dose Services2008-11-19Not applicableUs
Ranitidinetablet300 mg/1oralPhysicians Total Care, Inc.2003-09-19Not applicableUs
Ranitidinesyrup15 mg/mLoralWockhardt Limited2009-05-26Not applicableUs
Ranitidinetablet300 mg/1oralDIRECT RX2014-01-01Not applicableUs
Ranitidinetablet, film coated150 mg/1oralCardinal Health2009-11-062016-03-11Us
Ranitidinetablet150 mg/1oralWOCKHARDT USA LLC1998-12-17Not applicableUs
Ranitidinesolution15 mg/mLoralCarilion Materials Management2010-12-10Not applicableUs
Ranitidinetablet150 mg/1oralA S Medication Solutions2009-12-16Not applicableUs
Ranitidinetablet150 mg/1oralAidarex Pharmaceuticals LLC2009-12-16Not applicableUs
Ranitidinetablet150 mg/1oralAv Pak2015-08-04Not applicableUs
Ranitidinetablet150 mg/1oralState of Florida DOH Central Pharmacy2009-07-01Not applicableUs
Ranitidinetablet, film coated150 mg/1oralREMEDYREPACK INC.2013-03-26Not applicableUs
Ranitidinesyrup15 mg/mLoralDr. Reddy's Laboratories Limited2009-05-26Not applicableUs
Ranitidinesyrup15 mg/mLoralSun Pharmaceutical Industries, Inc.2011-10-03Not applicableUs
Ranitidinetablet150 mg/1oralContract Pharmacy Services Pa2010-06-30Not applicableUs
Ranitidinetablet, film coated150 mg/1oralMc Kesson Contract Packaging2011-10-26Not applicableUs
Ranitidinesolution75 mg/5mLoralQualitest Pharmaceuticals2010-07-01Not applicableUs
Ranitidinetablet300 mg/1oralSTAT Rx USA LLC2009-12-16Not applicableUs
Ranitidinetablet150 mg/1oralMedsource Pharmaceuticals2009-12-16Not applicableUs
Ranitidinetablet150 mg/1oralAmneal Pharmaceuticals of New York, LLC2009-12-16Not applicableUs
Ranitidinetablet150 mg/1oralCardinal Health2010-01-14Not applicableUs
Ranitidinetablet, film coated150 mg/1oralApotex Corp1997-09-13Not applicableUs
Ranitidinetablet150 mg/1oralWockhardt USA LLC.2009-12-11Not applicableUs
Ranitidinetablet, film coated150 mg/1oralProficient Rx LP2008-11-19Not applicableUs
Ranitidinesyrup15 mg/mLoralAurobindo Pharma Limited2010-07-28Not applicableUs
Ranitidinetablet, film coated300 mg/1oralGlenmark Generics Inc., USA2008-11-19Not applicableUs
Ranitidinetablet, film coated300 mg/1oralIVAX Pharmaceuticals, Inc.1998-04-01Not applicableUs
Ranitidinetablet, film coated150 mg/1oralBlenheim Pharmacal, Inc.2014-02-25Not applicableUs
Ranitidinetablet300 mg/1oralAv Kare, Inc.2014-08-18Not applicableUs
Ranitidinetablet, film coated300 mg/1oralUnit Dose Services2008-11-19Not applicableUs
Ranitidinesolution150 mg/mLoralPhysicians Total Care, Inc.2007-10-03Not applicableUs
Ranitidinetablet300 mg/1oralWockhardt Limited2009-12-11Not applicableUs
Ranitidinetablet300 mg/1oralAidarex Pharmaceuticals LLC2009-12-16Not applicableUs
Ranitidinetablet300 mg/1oralAv Pak2015-08-04Not applicableUs
Ranitidinetablet150 mg/1oralState of Florida DOH Central Pharmacy2009-07-01Not applicableUs
Ranitidinetablet150 mg/1oralPd Rx Pharmaceuticals, Inc.2009-12-16Not applicableUs
Ranitidinetablet, film coated75 mg/1oralREMEDYREPACK INC.2015-03-09Not applicableUs
Ranitidinetablet300 mg/1oralWOCKHARDT USA LLC1998-12-17Not applicableUs
Ranitidinetablet300 mg/1oralA S Medication Solutions2009-12-16Not applicableUs
Ranitidinesyrup15 mg/mLtopicalSandoz Inc.2011-10-25Not applicableUs
Ranitidine 75tablet75 mg/1oralREMEDYREPACK INC.2013-09-26Not applicableUs
Ranitidine Hydrochloridecapsule150 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs1997-10-22Not applicableUs
Ranitidine Hydrochloridetablet300 mg/1oralREMEDYREPACK INC.2010-10-25Not applicableUs
Ranitidine Hydrochloridetablet, film coated150 mg/1oralState of Florida DOH Central Pharmacy2009-07-01Not applicableUs
Ranitidine Hydrochlorideinjection25 mg/mLintramuscular; intravenousZydus Pharmaceuticals (USA) Inc.2013-03-01Not applicableUs
Ranitidine Hydrochloridesolution15 mg/mLoralPrecision Dose Inc.2011-04-252016-03-11Us
Ranitidine Hydrochloridetablet, film coated300 mg/1oralSandoz Inc1997-08-29Not applicableUs
Ranitidine Hydrochloridecapsule300 mg/1oralRebel Distributors Corp1997-10-22Not applicableUs
Ranitidine Hydrochloridetablet300 mg/1oralREMEDYREPACK INC.2011-10-03Not applicableUs
Ranitidine Hydrochloridecapsule150 mg/1oralDr. Reddy's Laboratories Limited2001-01-12Not applicableUs
Ranitidine Hydrochloridetablet, film coated150 mg/1oralMylan Institutional Inc.1997-07-11Not applicableUs
Ranitidine Hydrochloridetablet150 mg/1oralDIRECT RX2014-01-01Not applicableUs
Ranitidine Hydrochlorideinjection25 mg/mLintramuscular; intravenousCadila Healthcare Limited2013-03-01Not applicableUs
Ranitidine Hydrochloridetablet, film coated150 mg/1oralKeltman Pharmaceuticals Inc.2009-07-01Not applicableUs
Ranitidine Hydrochloridetablet, film coated150 mg/1oralCardinal Health2011-05-20Not applicableUs
Ranitidine Hydrochloridecapsule150 mg/1oralSandoz Inc1997-10-22Not applicableUs
Ranitidine Hydrochloridecapsule300 mg/1oralDr. Reddy's Laboratories Limited2001-04-01Not applicableUs
Ranitidine Hydrochloridetablet150 mg/1oralREMEDYREPACK INC.2011-04-14Not applicableUs
Ranitidine Hydrochloridesolution150 mg/10mLoralPrecision Dose Inc.2003-08-21Not applicableUs
Ranitidine Hydrochlorideinjection25 mg/mLintramuscular; intravenousCadila Healthcare Limited2013-03-01Not applicableUs
Ranitidine Hydrochloridetablet, film coated150 mg/1oralREMEDYREPACK INC.2014-10-13Not applicableUs
Ranitidine Hydrochloridecapsule300 mg/1oralSandoz Inc1997-10-22Not applicableUs
Ranitidine Hydrochloridetablet, film coated300 mg/1oralbryant ranch prepack1997-08-29Not applicableUs
Ranitidine Hydrochloridesolution75 mg/5mLoralPrecision Dose Inc.2006-10-132016-03-11Us
Ranitidine Hydrochloridetablet, film coated150 mg/1oralSandoz Inc1997-08-29Not applicableUs
Ranitidine Hydrochloridecapsule150 mg/1oralRebel Distributors Corp1997-10-22Not applicableUs
Ranitidine Hydrochloridetablet150 mg/1oralREMEDYREPACK INC.2011-08-11Not applicableUs
Ranitidine Hydrochlorideinjection25 mg/mLintramuscular; intravenousZydus Pharmaceuticals (USA) Inc.2013-03-01Not applicableUs
Approved Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
7 Select Acid Reducertablet, film coated150 mg/1oral7 Eleven2014-04-22Not applicableUs
Acid Reducertablet, film coated75 mg/1oralWin Co Foods, Llc2012-08-02Not applicableUs
Acid Reducertablet150 mg/1oralSafeway2008-02-20Not applicableUs
Acid Reducertablet150 mgoralApotex Inc2014-03-20Not applicableCanada
Acid Reducertablet75 mgoralLaboratoire Riva IncNot applicableNot applicableCanada
Acid Reducertablet150 mg/1oralWestern Family Foods Inc2008-03-14Not applicableUs
Acid Reducertablet, film coated150 mg/1oralCVS Pharmacy2015-09-14Not applicableUs
Acid Reducertablet150 mg/1oralValu Merchandisers Company2012-03-30Not applicableUs
Acid Reducertablet75 mg/1oralRite Aid Corporation2011-11-04Not applicableUs
Acid Reducertablet, film coated150 mg/1oralMeijer Distribution Inc2011-09-21Not applicableUs
Acid Reducertablet150 mg/1oralP and L Development of New York Corporation2013-03-25Not applicableUs
Acid Reducertablet75 mgoralVita Health Products Inc2006-03-312009-08-06Canada
Acid Reducertablet150 mg/1oralMc Kesson2014-01-07Not applicableUs
Acid Reducertablet150 mg/1oralFred's Inc.2012-03-30Not applicableUs
Acid Reducertablet150 mg/1oralPreferred Plus (Kinray)2014-01-27Not applicableUs
Acid Reducertablet150 mg/1oralSelect Brand2012-03-30Not applicableUs
Acid Reducertablet75 mgoralPharmascience Inc2004-07-13Not applicableCanada
Acid Reducertablet150 mg/1oralPremier Value2012-03-30Not applicableUs
Acid Reducertablet75 mg/1oralSafeway2009-05-29Not applicableUs
Acid Reducertablet75 mgoralVita Health Products Inc2008-01-31Not applicableCanada
Acid Reducertablet150 mg/1oralH E B2014-04-11Not applicableUs
Acid Reducertablet75 mg/1oralMedicine Shoppe International Inc2009-06-11Not applicableUs
Acid Reducertablet150 mg/1oralOhm Laboratories Inc.2011-06-28Not applicableUs
Acid Reducertablet, film coated150 mg/1oralCVS Pharmacy2011-09-21Not applicableUs
Acid Reducertablet, film coated150 mg/1oralRite Aid Corporation2011-10-26Not applicableUs
Acid Reducertablet75 mgoralApotex Inc1999-02-08Not applicableCanada
Acid Reducertablet, film coated150 mg/1oralShopko Stores Operating Co., LLC2013-06-05Not applicableUs
Acid Reducertablet75 mg/1oralHannaford Brothers Company2009-08-11Not applicableUs
Acid Reducertablet150 mg/1oralMc Kesson2014-01-07Not applicableUs
Acid Reducertablet75 mgoralWestcan Pharmaceuticals Ltd.Not applicableNot applicableCanada
Acid Reducertablet150 mg/1oralShopko Stores Operating Co., LLC2013-06-05Not applicableUs
Acid Reducertablet, film coated75 mg/1oralGood Sense2013-10-11Not applicableUs
Acid Reducertablet, film coated75 mg/1oralPreferred Plus (Kinray)2014-01-27Not applicableUs
Acid Reducertablet150 mg/1oralMajor Pharmaceuticals2013-10-01Not applicableUs
Acid Reducertablet150 mgoralPharmascience Inc2013-09-19Not applicableCanada
Acid Reducertablet, film coated150 mg/1oralH E B2015-11-30Not applicableUs
Acid Reducertablet75 mg/1oralMeijer Distribution Inc1998-09-29Not applicableUs
Acid Reducertablet, film coated75 mg/1oralOhm Laboratories Inc.2012-07-10Not applicableUs
Acid Reducertablet150 mg/1oralCardinal Health2013-09-25Not applicableUs
Acid Reducertablet75 mgoralMylan Pharmaceuticals Ulc1998-06-25Not applicableCanada
Acid Reducertablet75 mgoralNovopharm LimitedNot applicableNot applicableCanada
Acid Reducertablet, film coated150 mg/1oralShopko Stores Operating Co., LLC2013-06-05Not applicableUs
Acid Reducertablet150 mg/1oralWal Mart Stores, Inc2013-09-09Not applicableUs
Acid Reducertablet150 mg/1oralCVS Pharmacy2012-08-21Not applicableUs
Acid Reducertablet150 mg/1oralChain Drug Marketing Association Inc.2012-03-30Not applicableUs
Acid Reducertablet75 mg/1oralPublix Super Markets Inc2009-06-08Not applicableUs
Acid Reducertablet150 mg/1oralWin Co Foods, Llc2012-08-15Not applicableUs
Acid Reducertablet, film coated75 mg/1oralSafeway Inc.2013-12-13Not applicableUs
Acid Reducertablet75.0 mgoralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.2000-03-272004-07-26Canada
Acid Reducertablet, film coated150 mg/1oralH E B2015-11-25Not applicableUs
Acid Reducertablet, film coated150 mg/1oralMeijer Distribution Inc2013-08-23Not applicableUs
Acid Reducertablet75 mg/1oralHy Vee Inc2009-11-23Not applicableUs
Acid Reducertablet, film coated75 mg/1oralRite Aid2013-06-15Not applicableUs
Acid Reducertablet150 mg/1oralRite Aid Corporation2008-12-03Not applicableUs
Acid Reducertablet, film coated150 mg/1oralNash Finch Company2013-06-15Not applicableUs
Acid Reducertablet75 mg/1oralShopko Stores Operating Co., LLC2013-06-10Not applicableUs
Acid Reducer 150tablet, film coated150 mg/1oralSafeway2011-09-29Not applicableUs
Acid Reducer 150tablet, film coated150 mg/1oralHy Vee Inc2012-09-17Not applicableUs
Acid Reducer 150tablet, coated150 mg/1oralSAFEWAY INC2012-05-14Not applicableUs
Acid Reducer Maximum Strengthtablet150 mg/1oralMeijer Distribution Inc2008-02-13Not applicableUs
Acid Reducer Maximum Strengthtablet150 mg/1oralL. Perrigo Company2008-02-19Not applicableUs
Acid Reducer Maximum Strengthtablet, film coated150 mg/1oralFamily Dollar2013-06-15Not applicableUs
Acid Reducer Maximum Strengthtablet150 mg/1oralHy Vee Inc2008-02-17Not applicableUs
Acid Reducer Maximum Strength Non-prescriptiontablet150 mgoralMylan Pharmaceuticals UlcNot applicableNot applicableCanada
Acid Reducer Regular Strengthtablet, film coated75 mg/1oralKmart Corporation2013-06-15Not applicableUs
Acid Relieftablet75 mg/1oralWestern Family Foods Inc2009-05-28Not applicableUs
Acid Relieftablet, film coated150 mg/1oralWestern Family Foods Inc2013-11-27Not applicableUs
Acid Relieftablet, film coated150 mg/1oralWestern Family Foods Inc2011-10-03Not applicableUs
Aptidine 75tablet75 mg/1oralA P J Laboratories Limited2013-03-01Not applicableUs
Being Well Heartburn Relieftablet, film coated150 mg/1oralSave A Lot Food Stores Ltd2013-09-09Not applicableUs
Being Well Heartburn Relief Acid Reducertablet150 mg/1oralSave A Lot Food Stores Ltd2010-03-23Not applicableUs
Berkley and Jensen Acid Reducertablet, film coated150 mg/1oralBJWC2012-02-03Not applicableUs
Berkley and Jensen Acid Reducer Maximum Strengthtablet150 mg/1oralBJWC2009-09-23Not applicableUs
Berkley and Jensen Ranitidinetablet, film coated150 mg/1oralBJWC2014-07-01Not applicableUs
Care One Acid Reducertablet150 mg/1oralAmerican Sales Company2008-02-13Not applicableUs
Careone Acid Reducertablet, film coated150 mg/1oralAmerican Sales Company2013-11-30Not applicableUs
Careone Acid Reducertablet, film coated150 mg/1oralAmerican Sales Company2013-09-22Not applicableUs
Careone Acid Reducertablet75 mg/1oralAmerican Sales Company2009-05-29Not applicableUs
Cool Mint Acid Reducertablet, film coated150 mg/1oralRite Aid Corporation2011-12-07Not applicableUs
Dg Health Acid Reducertablet75 mg/1oralDolgencorp Inc2010-03-27Not applicableUs
Dg Health Acid Reducertablet, film coated150 mg/1oralDolgencorp, LLC2013-08-29Not applicableUs
Dg Health Acid Reducer Maximum Strengthtablet150 mg/1oralDolgencorp Inc2010-02-06Not applicableUs
Dg Health Heartburn Relieftablet, film coated150 mg/1oralDolgencorp, LLC2015-11-23Not applicableUs
Equalinetablet150 mg/1oralSUPERVALU INC.2011-06-28Not applicableUs
Equaline Heartburn Relieftablet, film coated150 mg/1oralSupervalu Inc2012-07-25Not applicableUs
Equaline Heartburn Relieftablet75 mg/1oralSupervalu Inc2009-05-11Not applicableUs
Equate Acid Reducertablet, film coated150 mg/1oralWal Mart Stores Inc2012-02-12Not applicableUs
Equate Ranitidinetablet, film coated150 mg/1oralWal Mart Stores Inc2012-02-12Not applicableUs
Equate Ranitidine Acid Reducertablet, film coated150 mg/1oralWal Mart Stores Inc2015-02-15Not applicableUs
Equate Ranitidine Acid Reducertablet, film coated150 mg/1oralWal Mart Stores Inc2013-02-22Not applicableUs
Exchange Select Acid Reducertablet75 mg/1oralArmy & Air Force Exchange Service2012-09-12Not applicableUs
Exchange Select Acid Reducertablet, film coated150 mg/1oralArmy & Air Force Exchange Service2014-01-06Not applicableUs
Family Wellness Acid Reducertablet75 mg/1oralFamily Dollar Services Inc2012-08-02Not applicableUs
Formu Care Ranitidinetablet150 mg/1oralAccess Business Group LLC2010-09-24Not applicableUs
Formucare Ranitidinetablet75 mg/1oralAccess Business Group International LLC2009-09-09Not applicableUs
Good Neighbor Pharmacy Acid Controltablet75 mg/1oralAmerisource Bergen2009-05-16Not applicableUs
Good Neighbor Pharmacy Acid Control 150tablet, film coated150 mg/1oralAmerisource Bergen2011-10-04Not applicableUs
Good Neighbor Pharmacy Acid Control 150tablet, film coated150 mg/1oralAmerisource Bergen2012-02-08Not applicableUs
Good Neighbor Pharmacy Acid Control 150 Maximum Strengthtablet150 mg/1oralAmerisource Bergen2008-02-19Not applicableUs
Good Sense Acid Reducertablet75 mg/1oralL Perrigo Company2009-05-21Not applicableUs
Good Sense Acid Reducertablet, film coated150 mg/1oralL. Perrigo Company2014-02-05Not applicableUs
Good Sense Acid Reducertablet, film coated150 mg/1oralL Perrigo Company2011-10-21Not applicableUs
Health Mart Acid Reducertablet75 mg/1oralMc Kesson2012-03-20Not applicableUs
Health Mart Acid Reducertablet150 mg/1oralMc Kesson2012-03-20Not applicableUs
Health Mart Acid Reducertablet, film coated150 mg/1oralMcKesson2012-03-20Not applicableUs
Healthy Accents Ranitidinetablet, film coated150 mg/1oralDZA Brands LLC2013-10-09Not applicableUs
Healthy Accents Ranitidinetablet150 mg/1oralDZA Brands LLC2008-11-12Not applicableUs
Heartburn Relieftablet, film coated150 mg/1oralH E B2013-07-23Not applicableUs
Heartburn Relieftablet, film coated150 mg/1oralKroger Company2013-08-31Not applicableUs
Heartburn Relieftablet, film coated150 mg/1oralH E B2011-11-25Not applicableUs
Heartburn Relieftablet75 mg/1oralSUPERVALU INC.2013-06-15Not applicableUs
Heartburn Relieftablet, film coated150 mg/1oralKroger Company2011-09-20Not applicableUs
Heartburn Relieftablet150 mg/1oralKroger Company2008-02-25Not applicableUs
Heartburn Relief 150tablet, film coated150 mg/1oralKroger Company2015-05-12Not applicableUs
Heartburn Relief 150tablet, film coated150 mg/1oralKroger Company2013-08-31Not applicableUs
Heartburn Relief 150 Maximum Strengthtablet, film coated150 mg/1oralSalado Sales, Inc.2013-06-15Not applicableUs
Heartburn Relief Acid Reducertablet75 mg/1oralKroger Company2009-05-22Not applicableUs
Heartburn Relief Maximum Strengthtablet, film coated150 mg/1oralGreenbrier International, Inc.2013-06-15Not applicableUs
Heartburn Relief Maximum Strengthtablet, film coated150 mg/1oralSUPERVALU INC.2013-06-15Not applicableUs
Heratburn Relieftablet, coated150 mg/1oralThe Kroger Co.2011-04-24Not applicableUs
Kirkland Signature Acid Reducertablet, film coated150 mg/1oralCostco Wholesale Company2013-04-24Not applicableUs
Leader Acid Controltablet, film coated150 mg/1oralCardinal Health2011-11-11Not applicableUs
Leader Acid Controltablet, film coated150 mg/1oralCardinal Health2014-03-11Not applicableUs
Leader Acid Controltablet, film coated150 mg/1oralCardinal Health2011-11-11Not applicableUs
Leader Acid Controltablet, film coated150 mg/1oralREMEDYREPACK INC.2015-03-27Not applicableUs
Leader Acid Controltablet, film coated150 mg/1oralCardinal Health2011-05-25Not applicableUs
Leader Acid Control Acid Reducertablet75 mg/1oralCardinal Health2009-05-21Not applicableUs
Leader Acid Control Maximum Strengthtablet150 mg/1oralCardinal Health2008-02-20Not applicableUs
Major Ranitidine Maximum Strengthtablet150 mg/1oralMajor Pharmaceuticals2008-02-18Not applicableUs
Maximum Strengthtablet150 mg/1oralPublix Super Markets Inc2009-01-27Not applicableUs
Maximum Strength Acid Reducertablet150 mg/1oralL.N.K. International, Inc.2013-06-15Not applicableUs
Maximum Strength Acid Reducertablet150 mgoralVita Health Products Inc2007-10-12Not applicableCanada
Maximum Strength Acid Reducer Without Prescriptiontablet150 mgoralPharmel IncNot applicableNot applicableCanada
Maximum Strength Acid Reducer Without Prescriptiontablet150 mgoralPharmascience Inc2007-07-18Not applicableCanada
Maximum Strength Ranitidinetablet, film coated150 mg/1oralPublix Super Markets Inc2013-11-25Not applicableUs
Maximum Strength Zantactablet, coated150 mg/1oralBoehringer Ingelheim Pharmaceuticals Inc.2006-12-21Not applicableUs
Ranitidinetablet, film coated75 mg/1oralREMEDYREPACK INC.2015-11-12Not applicableUs
Ranitidinetablet150 mg/1oralShopko Stores Operating Co., LLC2012-03-30Not applicableUs
Ranitidinetablet75 mg/1oralDr. Reddy's Laboratories Limited2000-03-01Not applicableUs
Ranitidinetablet, film coated75 mg/1oralHealth Mart2013-09-20Not applicableUs
Ranitidinetablet, film coated75 mg/1oralMajor Pharmaceuticals2013-10-01Not applicableUs
Ranitidinetablet, coated150 mg/1oralWockhardt USA LLC.2007-11-26Not applicableUs
Ranitidinetablet, film coated75 mg/1oralWalgreen Company2013-09-24Not applicableUs
Ranitidinetablet, film coated75 mg/1oralAmerisource Bergen2013-09-06Not applicableUs
Ranitidinetablet, film coated75 mg/1oralValu Merchandisers Company2012-07-10Not applicableUs
Ranitidinetablet, film coated75 mg/1oralSUPERVALU INC.2012-07-10Not applicableUs
Ranitidinetablet, film coated75 mg/1oralCardinal Health2013-09-25Not applicableUs
Ranitidinetablet, coated150 mg/1oralDr. Reddy's Laboratories Limited2009-12-02Not applicableUs
Ranitidinetablet75 mg/1oralP and L Development of New York Corporation2013-03-19Not applicableUs
Ranitidinetablet, film coated75 mg/1oralSunmark2013-09-20Not applicableUs
Ranitidinetablet, film coated75 mg/1oralFred's Inc.2013-09-01Not applicableUs
Ranitidinetablet150 mg/1oralShasun Pharmaceuticals Limited2011-06-28Not applicableUs
Ranitidinetablet, film coated150 mg/1oralApotex Corp.2013-07-15Not applicableUs
Ranitidinetablet, coated75 mg/1oralWockhardt Limited2008-07-31Not applicableUs
Ranitidinetablet, film coated150 mg/1oralLiberty Pharmaceuticals, Inc.2013-07-15Not applicableUs
Ranitidinetablet75 mgoralPharmascience IncNot applicableNot applicableCanada
Ranitidinetablet150 mg/1oralShopko Stores Operating Co., LLC.2010-07-11Not applicableUs
Ranitidinetablet150 mg/1oralMedline Industries, Inc.2012-03-30Not applicableUs
Ranitidinetablet75 mg/1oralShasun Pharmaceuticals Limited2012-02-29Not applicableUs
Ranitidinetablet, film coated75 mg/1oralApotex Corp.2005-01-24Not applicableUs
Ranitidinetablet, coated75 mg/1oralWockhardt USA LLC.2008-07-31Not applicableUs
Ranitidinetablet, film coated75 mg/1oralWal Mart Stores, Inc2012-07-10Not applicableUs
Ranitidinetablet, coated150 mg/1oralWockhardt Limited2007-11-26Not applicableUs
Ranitidinetablet, film coated75 mg/1oralCVS Pharmacy, Inc2013-09-19Not applicableUs
Ranitidinetablet, film coated75 mg/1oralChain Drug Marketing Association Inc.2012-07-10Not applicableUs
Ranitidine - Acid Reducertablet, film coated75 mg/1oralChain Drug Consortium, Llc.2012-07-10Not applicableUs
Ranitidine 150tablet, coated150 mg/1oralWalmart Stores Inc.2010-01-05Not applicableUs
Ranitidine 75tablet75 mg/1oralThe Kroger Co.2011-03-31Not applicableUs
Ranitidine 75tablet75 mg/1oralTarget Brands Inc2013-11-22Not applicableUs
Ranitidine 75tablet75 mg/1oralMeijer Distribution Inc2014-09-22Not applicableUs
Ranitidine 75tablet75 mg/1oralMajor Pharmaceuticals2009-05-26Not applicableUs
Ranitidine Acid Reducertablet, film coated150 mg/1oralHy Vee Inc2013-12-02Not applicableUs
Ranitidine Hydrochloridetablet, film coated75 mg/1oralSelect Brand2012-07-10Not applicableUs
Ranitidine Non Prescriptiontablet150 mgoralSandoz Canada IncorporatedNot applicableNot applicableCanada
Regular Strength Acid Reducertablet75 mg/1oralFamily Dollar2013-06-15Not applicableUs
Regular Strength Acid Reducertablet150 mg/1oralFamily Dollar2011-06-28Not applicableUs
Regular Strength Acid Reducertablet75 mg/1oralL.N.K. International, Inc.2013-06-15Not applicableUs
Regular Strength Acid Reducertablet75 mg/1oralFamily Dollar2013-09-24Not applicableUs
Rexall Heartburn Relieftablet, film coated150 mg/1oralDolgencorp, LLC2011-10-03Not applicableUs
Riva-ranitidine 75mgtablet75 mgoralLaboratoire Riva Inc1999-07-27Not applicableCanada
Rx Act Heartburn Relieftablet150 mg/1oralH E B2008-02-20Not applicableUs
Shoprite Acid Reducertablet150 mg/1oralWakefern Food Corporation2013-06-16Not applicableUs
Shoprite Acid Reducertablet, film coated150 mg/1oralWakefern Food Corporation2013-06-20Not applicableUs
Shoprite Acid Reducer Maximum Strengthtablet, film coated150 mg/1oralWakefern Food Corporation2013-06-16Not applicableUs
Signature Care Acid Controltablet, film coated150 mg/1oralSafeway2015-09-01Not applicableUs
Smart Sense Acid Reducertablet, film coated150 mg/1oralKmart Corporation2011-11-22Not applicableUs
Smart Sense Acid Reducertablet75 mg/1oralKmart Corporation2010-12-15Not applicableUs
Smart Sense Acid Reducertablet150 mg/1oralKmart Corporation2010-11-24Not applicableUs
Smart Sense Ranitidinetablet, film coated150 mg/1oralKmart Corporation2014-03-21Not applicableUs
Smart Sense Ranitidinetablet, film coated150 mg/1oralKmart Corporation2011-05-27Not applicableUs
Smart Sense Ranitidinetablet150 mg/1oralKmart Corporation2010-11-24Not applicableUs
Sunmark Acid Reducertablet75 mg/1oralMc Kesson2009-07-10Not applicableUs
Sunmark Acid Reducer Maximum Strengthtablet150 mg/1oralMc Kesson2008-02-13Not applicableUs
Topcare Heartburn Relieftablet75 mg/1oralTopco Associates LLC2009-06-11Not applicableUs
Topcare Heartburn Relief 150tablet, film coated150 mg/1oralTopco Associates LLC2011-10-10Not applicableUs
Topcare Heartburn Relief 150tablet150 mg/1oralTopco Associates LLC2008-02-13Not applicableUs
Topcare Heartburn Relief 150tablet, film coated150 mg/1oralTopco Associates LLC2013-10-08Not applicableUs
Up and Up Acid Reducer Non Prescription Strengthtablet75 mg/1oralTarget Corporation2009-07-31Not applicableUs
Up and Up Ranitidinetablet, film coated150 mg/1oralTarget Corporation2015-04-01Not applicableUs
Up and Up Ranitidinetablet, film coated150 mg/1oralTarget Corporation2013-09-11Not applicableUs
Up and Up Ranitidinetablet150 mg/1oralTarget Corporation2012-05-03Not applicableUs
Wal Zan 150tablet, film coated150 mg/1oralWalgreen Company2011-09-17Not applicableUs
Wal Zan 75tablet75 mg/1oralWalgreen Company2009-02-24Not applicableUs
Wal Zan Acid Reducer Maximum Strengthtablet150 mg/1oralWalgreen Company2008-02-04Not applicableUs
Wal-zantablet75 mg/1oralWalgreens Company2015-07-31Not applicableUs
Wal-zantablet, coated150 mg/1oralWalgreens Company2011-06-11Not applicableUs
Wal-zantablet150 mg/1oralWalgreens Company2015-07-31Not applicableUs
Wal-zantablet150 mg/1oralWalgreen Company2011-06-28Not applicableUs
Wal-zan 75tablet75 mg/1oralWalgreens Company2014-01-06Not applicableUs
Zantactablet, coated75 mg/1oralCentral Texas Community Health Centers2006-12-21Not applicableUs
Zantac - Tab 75mgtablet75 mgoralMcneil Consumer Healthcare Division Of Johnson & Johnson Inc1997-09-26Not applicableCanada
Zantac 150tablet150 mg/1oralBoehringer Ingelheim Promeco s.a. De c.v.2016-04-15Not applicableUs
Zantac 150 Acid Reducertablet150 mg/1oralLil' Drug Store Products, Inc2010-11-01Not applicableUs
Zantac 75tablet75 mg/1oralBoehringer Ingelheim Promeco s.a. De c.v.2016-04-15Not applicableUs
Zantac 75tablet, coated75 mg/1oralBoehringer Ingelheim Pharmaceuticals Inc.2006-12-21Not applicableUs
Zantac 75tablet, coated75 mg/1oralCarilion Materials Management2006-12-21Not applicableUs
Zantac Maximum Strength 150 Cool Minttablet, coated150 mg/1oralBoehringer Ingelheim Pharmaceuticals Inc.2006-12-21Not applicableUs
Zantac Maximum Strength Non-prescriptiontablet150 mgoralMcneil Consumer Healthcare Division Of Johnson & Johnson Inc2007-03-09Not applicableCanada
Unapproved/Other Products Not Available
International Brands
NameCompany
AlquenNot Available
CoralenNot Available
GastrolavNot Available
GastrosedolNot Available
KuracidNot Available
Nu-RanitNot Available
Pep-RaniNot Available
PtinolinNot Available
RaniberlNot Available
RaniblocNot Available
RanicuxNot Available
RanidilNot Available
RanidinNot Available
RanidineNot Available
RaniduraNot Available
RanifurNot Available
RanigastNot Available
RaniplexNot Available
RanisanNot Available
RanitabNot Available
RaniticNot Available
RanitidinNot Available
RanitinNot Available
RanitineNot Available
RanobelNot Available
RantacidNot Available
RanuberNot Available
RenatacNot Available
SostrilNot Available
TanidinaNot Available
ToriolNot Available
UlcodinNot Available
ZandidNot Available
ZanticNot Available
Brand mixtures
NameLabellerIngredients
GabitidinePhysician Therapeutics Llc
SentradinePhysician Therapeutics Llc
Salts
Name/CASStructureProperties
Ranitidine bismuth citrate
ThumbNot applicableDBSALT001128
Ranitidine Hydrochloride
66357-59-3
Thumb
  • InChI Key: GGWBHVILAJZWKJ-KJEVSKRMSA-N
  • Monoisotopic Mass: 350.117939019
  • Average Mass: 350.865
DBSALT000487
Categories
UNII884KT10YB7
CAS number66357-35-5
WeightAverage: 314.404
Monoisotopic: 314.14126128
Chemical FormulaC13H22N4O3S
InChI KeyInChIKey=VMXUWOKSQNHOCA-UKTHLTGXSA-N
InChI
InChI=1S/C13H22N4O3S/c1-14-13(9-17(18)19)15-6-7-21-10-12-5-4-11(20-12)8-16(2)3/h4-5,9,14-15H,6-8,10H2,1-3H3/b13-9+
IUPAC Name
dimethyl[(5-{[(2-{[(E)-1-(methylamino)-2-nitroethenyl]amino}ethyl)sulfanyl]methyl}furan-2-yl)methyl]amine
SMILES
CN\C(NCCSCC1=CC=C(CN(C)C)O1)=C/[N+]([O-])=O
Taxonomy
DescriptionThis compound belongs to the class of organic compounds known as aralkylamines. These are alkylamines in which the alkyl group is substituted at one carbon atom by an aromatic hydrocarbyl group.
KingdomOrganic compounds
Super ClassOrganonitrogen compounds
ClassAmines
Sub ClassAralkylamines
Direct ParentAralkylamines
Alternative Parents
Substituents
  • Aralkylamine
  • Heteroaromatic compound
  • Furan
  • Organic nitro compound
  • Tertiary aliphatic amine
  • Tertiary amine
  • Organic nitrite
  • C-nitro compound
  • Oxacycle
  • Organoheterocyclic compound
  • Dialkylthioether
  • Organic 1,3-dipolar compound
  • Propargyl-type 1,3-dipolar organic compound
  • Allyl-type 1,3-dipolar organic compound
  • Sulfenyl compound
  • Thioether
  • Organic oxoazanium
  • Hydrocarbon derivative
  • Organic salt
  • Organosulfur compound
  • Organooxygen compound
  • Organic zwitterion
  • Aromatic heteromonocyclic compound
Molecular FrameworkAromatic heteromonocyclic compounds
External Descriptors
Pharmacology
IndicationUsed in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).
PharmacodynamicsRanitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.
Mechanism of actionThe H2 antagonists are competitive inhibitors of histamine at the parietal cell H2 receptor. They suppress the normal secretion of acid by parietal cells and the meal-stimulated secretion of acid. They accomplish this by two mechanisms: histamine released by ECL cells in the stomach is blocked from binding on parietal cell H2 receptors which stimulate acid secretion, and other substances that promote acid secretion (such as gastrin and acetylcholine) have a reduced effect on parietal cells when the H2 receptors are blocked.
Related Articles
AbsorptionApproximately 50% bioavailability orally.
Volume of distribution
  • 1.4 L/kg
  • 1.76 L/kg [clinically significant renal function impairment (creatinine clearance 25 to 35 mL/min)]
Protein binding15%
Metabolism

Hepatic. Ranitidine is metabolized to the N-oxide, S-oxide, and N-desmethyl metabolites, accounting for approximately 4%, 1%, and 1% of the dose, respectively.

Route of eliminationThe principal route of excretion is the urine (active tubular excretion, renal clearance 410mL/min), with approximately 30% of the orally administered dose collected in the urine as unchanged drug in 24 hours.
Half life2.8-3.1 hours
Clearance
  • 29 mL/min [clinically significant renal function impairment]
  • 3 mL/min/Kg [neonatal patients]
ToxicityLD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.
Affected organisms
  • Humans and other mammals
Pathways
PathwayCategorySMPDB ID
Ranitidine Action PathwayDrug actionSMP00230
SNP Mediated EffectsNot Available
SNP Mediated Adverse Drug ReactionsNot Available
ADMET
Predicted ADMET features
PropertyValueProbability
Human Intestinal Absorption+0.9936
Blood Brain Barrier-0.8783
Caco-2 permeable-0.5838
P-glycoprotein substrateSubstrate0.8527
P-glycoprotein inhibitor INon-inhibitor0.8782
P-glycoprotein inhibitor IINon-inhibitor0.8893
Renal organic cation transporterNon-inhibitor0.8177
CYP450 2C9 substrateNon-substrate0.7702
CYP450 2D6 substrateSubstrate0.7414
CYP450 3A4 substrateNon-substrate0.5565
CYP450 1A2 substrateNon-inhibitor0.9046
CYP450 2C9 inhibitorNon-inhibitor0.9071
CYP450 2D6 inhibitorNon-inhibitor0.923
CYP450 2C19 inhibitorNon-inhibitor0.9025
CYP450 3A4 inhibitorNon-inhibitor0.8308
CYP450 inhibitory promiscuityLow CYP Inhibitory Promiscuity0.7819
Ames testNon AMES toxic0.9132
CarcinogenicityNon-carcinogens0.8077
BiodegradationNot ready biodegradable0.9249
Rat acute toxicity2.0903 LD50, mol/kg Not applicable
hERG inhibition (predictor I)Strong inhibitor0.8628
hERG inhibition (predictor II)Non-inhibitor0.8734
ADMET data is predicted using admetSAR, a free tool for evaluating chemical ADMET properties. (23092397 )
Pharmacoeconomics
Manufacturers
  • Dr reddys laboratories ltd
  • Genpharm inc
  • Sandoz inc
  • Teva pharmaceuticals usa inc
  • Glaxosmithkline
  • Bedford laboratories div ben venue laboratories inc
  • Ben venue laboratories inc
  • Alpharma us pharmaceuticals division
  • Amneal pharmaceuticals
  • Apotex inc
  • Aurobindo pharma usa inc
  • Cypress pharmaceutical inc
  • Pharmaceutical assoc inc div beach products
  • Ranbaxy laboratories ltd
  • Vintage pharmaceuticals inc
  • Wockhardt ltd
  • Boehringer ingelheim pharmaceuticals inc
  • Amneal pharmaceuticals ny llc
  • Boehringer ingelheim corp
  • Contract pharmacal corp
  • Dr reddys laboratories inc
  • Glenmark generics inc usa
  • Ivax pharmaceuticals inc sub teva pharmaceuticals usa
  • Mylan pharmaceuticals inc
  • Par pharmaceutical inc
  • L perrigo co
  • Ranbaxy pharmaceuticals inc
  • Torpharm inc
  • Watson laboratories inc
  • Wockhardt americas inc
  • Boehringer ingelheim
Packagers
Dosage forms
FormRouteStrength
Tabletoral75.0 mg
Tabletoral150 mg/1
Kit
Tabletoral75 mg/1
Tablet, film coatedoral150 mg/1
Tabletoral150 mg
Tabletoral300 mg
Tabletoral400 mg
Solutionoral15 mg/mL
Solutionoral150 mg/mL
Solutionoral75 mg/5mL
Syruporal15 mg/mL
Syruptopical15 mg/mL
Tabletoral300 mg/1
Tablet, film coatedoral300 mg/1
Tablet, film coatedoral75 mg/1
Capsuleoral150 mg/1
Capsuleoral300 mg/1
Injectionintramuscular; intravenous25 mg/mL
Solutionoral150 mg/10mL
Solutionoral15 mg
Tablet, coatedoral150 mg/1
Injection, solutionintramuscular; intravenous25 mg/mL
Liquidintramuscular; intravenous25 mg
Solutionintramuscular; intravenous25 mg
Tabletoral75 mg
Tablet, coatedoral75 mg/1
Capsuleoral150 mg
Capsuleoral300 mg
Prices
Unit descriptionCostUnit
Zantac 300 mg tablet7.96USD tablet
Ranitidine hcl powder5.2USD g
Zantac EFFERdose 25 mg Effervescent Tabs4.18USD tab
Zantac 25 efferdose tablet4.02USD tablet
Zantac 150 mg tablet3.11USD tablet
Ranitidine HCl 300 mg capsule2.85USD capsule
Ranitidine HCl 300 mg tablet2.79USD tablet
Ranitidine 300 mg tablet2.69USD tablet
Ranitidine hcl 25 mg/ml vial2.0USD ml
Zantac 25 mg/ml vial2.0USD ml
Ranitidine HCl 150 mg capsule1.58USD capsule
Zantac 25 mg/ml1.58USD ml
Ranitidine HCl 150 mg tablet1.54USD tablet
Ranitidine 150 mg tablet1.48USD tablet
Ranitidine 25 mg/ml1.26USD ml
Ranitidine HCl 15 mg/ml Syrup1.0USD ml
Ratio-Ranitidine 300 mg Tablet0.82USD tablet
Apo-Ranitidine 300 mg Tablet0.82USD tablet
Co Ranitidine 300 mg Tablet0.82USD tablet
Mylan-Ranitidine 300 mg Tablet0.82USD tablet
Nu-Ranit 300 mg Tablet0.82USD tablet
Pms-Ranitidine 300 mg Tablet0.82USD tablet
Ran-Ranitidine 300 mg Tablet0.82USD tablet
Zantac 15 mg/ml Syrup0.81USD ml
Zantac 75 tablet0.49USD tablet
Apo-Ranitidine 150 mg Tablet0.42USD tablet
Co Ranitidine 150 mg Tablet0.42USD tablet
Mylan-Ranitidine 150 mg Tablet0.42USD tablet
Nu-Ranit 150 mg Tablet0.42USD tablet
Pms-Ranitidine 150 mg Tablet0.42USD tablet
Ran-Ranitidine 150 mg Tablet0.42USD tablet
Ratio-Ranitidine 150 mg Tablet0.42USD tablet
Novo-Ranidine 300 mg Tablet0.38USD tablet
Phl-Ranitidine 300 mg Tablet0.38USD tablet
Sandoz Ranitidine 300 mg Tablet0.38USD tablet
Zantac 300 mg Tablet0.38USD tablet
Zantac 75 mg tablet0.28USD tablet
Wal-zan 75 mg tablet0.27USD tablet
Zantac 15 mg/ml Solution0.23USD ml
Ranitidine hcl 75 mg tablet0.22USD tablet
Sm acid reducer 75 mg tablet0.22USD tablet
Acid reducer 150 mg tablet0.2USD tablet
Wal-zan 75 tablet0.2USD tablet
Novo-Ranidine 150 mg Tablet0.19USD tablet
Phl-Ranitidine 150 mg Tablet0.19USD tablet
Sandoz Ranitidine 150 mg Tablet0.19USD tablet
Zantac 150 mg Tablet0.19USD tablet
CVS Pharmacy ranitidine 75 mg tablet0.15USD tablet
Apo-Ranitidine 15 mg/ml Solution0.12USD ml
Novo-Ranidine 15 mg/ml Solution0.12USD ml
Acid reducer 75 mg tablet0.11USD tablet
CVS Pharmacy acid reducer 75 mg tablet0.11USD tablet
Qc ranitidine 75 mg tablet0.07USD tablet
DrugBank does not sell nor buy drugs. Pricing information is supplied for informational purposes only.
Patents
Patent NumberPediatric ExtensionApprovedExpires (estimated)
CA1332610 No1994-10-182011-10-18Canada
US5098715 No1993-12-202010-12-20Us
US5102665 No1992-12-232009-12-23Us
Properties
StateSolid
Experimental Properties
PropertyValueSource
melting point69-70 °CPhysProp
water solubility24.7 mg/mLNot Available
logP0.27SANGSTER (1993)
Caco2 permeability-6.31ADME Research, USCD
Predicted Properties
PropertyValueSource
Water Solubility0.0795 mg/mLALOGPS
logP0.79ALOGPS
logP0.98ChemAxon
logS-3.6ALOGPS
pKa (Strongest Basic)8.08ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count5ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area86.26 Å2ChemAxon
Rotatable Bond Count10ChemAxon
Refractivity95.15 m3·mol-1ChemAxon
Polarizability33.58 Å3ChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Mass Spec (NIST)Not Available
Spectra
Spectrum TypeDescriptionSplash Key
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 10V, Positive (Annotated)splash10-01ot-7906000000-d0c73cd55f0c88b5292cView in MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 25V, Positive (Annotated)splash10-004j-2900000000-72810aa2bdb337010c71View in MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 40V, Positive (Annotated)splash10-0f92-3900000000-4984706aec6a10a3a701View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, Negativesplash10-03di-0009000000-3a9ffadb8ced05c4f2f1View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 20V, Negativesplash10-006x-0900000000-26410712c1d9fca3970fView in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 30V, Negativesplash10-02ml-0900000000-b8d8d8a38eb5ff79811dView in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 40V, Negativesplash10-03di-2900000000-417be0cb4c8a324c3ae4View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 50V, Negativesplash10-03di-5900000000-ca80edf051507a622e91View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, Positivesplash10-014i-0009000000-e8f56e6282043759674eView in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 20V, Positivesplash10-00vi-0933000000-aaee0f5a149286ba8834View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 30V, Positivesplash10-0059-1900000000-52e4e1bcfef85a6bafeaView in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 40V, Positivesplash10-0faj-2900000000-e412e77b79750d8bb513View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 50V, Positivesplash10-0uea-4900000000-76d786153c89ecf65f8cView in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-IT (LC/MSD Trap XCT, Agilent Technologies) , Positivesplash10-00fr-0930000000-01f54848489d6a7b4da4View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-IT (LC/MSD Trap XCT, Agilent Technologies) , Positivesplash10-00di-0970000000-49b8e0b710b97f5d5da6View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-IT (LC/MSD Trap XCT, Agilent Technologies) , Positivesplash10-00kf-0900000000-cf634d229fba340e6e3bView in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-IT (LC/MSD Trap XCT, Agilent Technologies) , Positivesplash10-001i-0900000000-09008c251fc8dd33b8bfView in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-IT (LC/MSD Trap XCT, Agilent Technologies) , Positivesplash10-00e9-4900000000-350ded3a1f334f8103b1View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-IT (LC/MSD Trap XCT, Agilent Technologies) , Positivesplash10-052f-0900000000-14196f34248aa3cac7fcView in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-IT (LC/MSD Trap XCT, Agilent Technologies) , Positivesplash10-0f79-0900000000-0a386c1d346e41534469View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-IT (LC/MSD Trap XCT, Agilent Technologies) , Positivesplash10-0udi-0900000000-4296a8171c03e3b2b689View in MoNA
1D NMR1H NMR SpectrumNot Available
2D NMR[1H,13C] 2D NMR SpectrumNot Available
References
Synthesis Reference

John W. Clitherow, “Intermediates in the preparation of ranitidine.” U.S. Patent US4413135, issued November, 1981.

US4413135
General ReferencesNot Available
External Links
ATC CodesA02BA02A02BA07
AHFS Codes
  • 56:28.12
PDB EntriesNot Available
FDA labelDownload (247 KB)
MSDSDownload (73.9 KB)
Interactions
Drug Interactions
Drug
3,4-Methylenedioxyamphetamine3,4-Methylenedioxyamphetamine may decrease the sedative activities of Ranitidine.
3,4-Methylenedioxymethamphetamine3,4-Methylenedioxymethamphetamine may decrease the sedative activities of Ranitidine.
AbirateroneThe serum concentration of Ranitidine can be increased when it is combined with Abiraterone.
AcebutololThe serum concentration of Acebutolol can be increased when it is combined with Ranitidine.
AcetaminophenThe serum concentration of Acetaminophen can be increased when it is combined with Ranitidine.
AcetohexamideThe serum concentration of Acetohexamide can be increased when it is combined with Ranitidine.
Acetylsalicylic acidThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Ranitidine.
AfatinibThe serum concentration of Afatinib can be increased when it is combined with Ranitidine.
AlbendazoleThe serum concentration of Ranitidine can be increased when it is combined with Albendazole.
AldosteroneThe serum concentration of Ranitidine can be decreased when it is combined with Aldosterone.
AldosteroneThe serum concentration of Aldosterone can be increased when it is combined with Ranitidine.
AlectinibThe serum concentration of Ranitidine can be increased when it is combined with Alectinib.
AlfentanilThe serum concentration of Ranitidine can be increased when it is combined with Alfentanil.
AlitretinoinThe serum concentration of Alitretinoin can be increased when it is combined with Ranitidine.
AmantadineThe serum concentration of Ranitidine can be increased when it is combined with Amantadine.
AmbrisentanThe serum concentration of Ambrisentan can be increased when it is combined with Ranitidine.
Aminohippuric acidThe serum concentration of Ranitidine can be increased when it is combined with Aminohippuric acid.
AmiodaroneThe serum concentration of Ranitidine can be decreased when it is combined with Amiodarone.
AmitriptylineThe serum concentration of Amitriptyline can be increased when it is combined with Ranitidine.
AmlodipineThe serum concentration of Ranitidine can be increased when it is combined with Amlodipine.
AmphetamineAmphetamine may decrease the sedative activities of Ranitidine.
AmprenavirThe serum concentration of Ranitidine can be decreased when it is combined with Amprenavir.
AmsacrineThe serum concentration of Ranitidine can be increased when it is combined with Amsacrine.
ApixabanThe serum concentration of Apixaban can be increased when it is combined with Ranitidine.
AripiprazoleThe serum concentration of Aripiprazole can be increased when it is combined with Ranitidine.
ArmodafinilThe metabolism of Ranitidine can be decreased when combined with Armodafinil.
Arsenic trioxideThe serum concentration of Arsenic trioxide can be increased when it is combined with Ranitidine.
ArtemetherThe metabolism of Ranitidine can be decreased when combined with Artemether.
AstemizoleThe serum concentration of Ranitidine can be increased when it is combined with Astemizole.
AtazanavirThe serum concentration of Atazanavir can be increased when it is combined with Ranitidine.
AtenololThe serum concentration of Atenolol can be increased when it is combined with Ranitidine.
AtomoxetineThe metabolism of Ranitidine can be decreased when combined with Atomoxetine.
AtorvastatinThe serum concentration of Ranitidine can be increased when it is combined with Atorvastatin.
AxitinibThe serum concentration of Axitinib can be increased when it is combined with Ranitidine.
AzelastineThe serum concentration of Ranitidine can be increased when it is combined with Azelastine.
AzithromycinThe serum concentration of Ranitidine can be increased when it is combined with Azithromycin.
BenzocaineThe serum concentration of Ranitidine can be increased when it is combined with Benzocaine.
BenzphetamineBenzphetamine may decrease the sedative activities of Ranitidine.
Benzylpenicilloyl PolylysineRanitidine may decrease effectiveness of Benzylpenicilloyl Polylysine as a diagnostic agent.
BepridilThe serum concentration of Ranitidine can be increased when it is combined with Bepridil.
BetahistineThe therapeutic efficacy of Betahistine can be decreased when used in combination with Ranitidine.
BetamethasoneThe serum concentration of Betamethasone can be increased when it is combined with Ranitidine.
BetaxololThe metabolism of Ranitidine can be decreased when combined with Betaxolol.
BiperidenThe serum concentration of Ranitidine can be increased when it is combined with Biperiden.
BoceprevirThe serum concentration of Boceprevir can be increased when it is combined with Ranitidine.
BortezomibThe metabolism of Ranitidine can be decreased when combined with Bortezomib.
BosutinibThe serum concentration of Bosutinib can be increased when it is combined with Ranitidine.
Brentuximab vedotinThe serum concentration of Brentuximab vedotin can be increased when it is combined with Ranitidine.
BromocriptineThe serum concentration of Bromocriptine can be increased when it is combined with Ranitidine.
BuprenorphineThe serum concentration of Ranitidine can be increased when it is combined with Buprenorphine.
BupropionThe metabolism of Ranitidine can be decreased when combined with Bupropion.
BuspironeThe serum concentration of Ranitidine can be increased when it is combined with Buspirone.
CabazitaxelThe serum concentration of Cabazitaxel can be increased when it is combined with Ranitidine.
CaffeineThe serum concentration of Caffeine can be increased when it is combined with Ranitidine.
CamptothecinThe serum concentration of Camptothecin can be increased when it is combined with Ranitidine.
CanagliflozinThe serum concentration of Canagliflozin can be increased when it is combined with Ranitidine.
CandesartanThe serum concentration of Ranitidine can be increased when it is combined with Candesartan.
CaptoprilThe serum concentration of Ranitidine can be increased when it is combined with Captopril.
CarbamazepineThe serum concentration of Ranitidine can be decreased when it is combined with Carbamazepine.
CarbamazepineThe serum concentration of Carbamazepine can be increased when it is combined with Ranitidine.
CarfilzomibThe serum concentration of Carfilzomib can be increased when it is combined with Ranitidine.
CarvedilolThe serum concentration of Ranitidine can be increased when it is combined with Carvedilol.
CaspofunginThe serum concentration of Ranitidine can be increased when it is combined with Caspofungin.
CefditorenThe serum concentration of Cefditoren can be decreased when it is combined with Ranitidine.
CefpodoximeRanitidine can cause a decrease in the absorption of Cefpodoxime resulting in a reduced serum concentration and potentially a decrease in efficacy.
CefuroximeRanitidine can cause a decrease in the absorption of Cefuroxime resulting in a reduced serum concentration and potentially a decrease in efficacy.
CelecoxibThe metabolism of Ranitidine can be decreased when combined with Celecoxib.
CeritinibThe serum concentration of Ceritinib can be increased when it is combined with Ranitidine.
CerivastatinThe serum concentration of Cerivastatin can be increased when it is combined with Ranitidine.
ChloramphenicolThe metabolism of Ranitidine can be decreased when combined with Chloramphenicol.
ChloroquineThe serum concentration of Ranitidine can be increased when it is combined with Chloroquine.
ChlorphentermineChlorphentermine may decrease the sedative activities of Ranitidine.
ChlorpromazineThe serum concentration of Chlorpromazine can be increased when it is combined with Ranitidine.
ChlorpropamideThe serum concentration of Chlorpropamide can be increased when it is combined with Ranitidine.
ChlorprothixeneThe serum concentration of Ranitidine can be increased when it is combined with Chlorprothixene.
CholecalciferolThe metabolism of Ranitidine can be decreased when combined with Cholecalciferol.
CholesterolThe serum concentration of Ranitidine can be increased when it is combined with Cholesterol.
Cholic AcidThe serum concentration of Ranitidine can be decreased when it is combined with Cholic Acid.
CilazaprilThe serum concentration of Ranitidine can be increased when it is combined with Cilazapril.
CimetidineThe serum concentration of Ranitidine can be decreased when it is combined with Cimetidine.
CimetidineThe serum concentration of Cimetidine can be increased when it is combined with Ranitidine.
CinacalcetThe metabolism of Ranitidine can be decreased when combined with Cinacalcet.
CiprofloxacinThe serum concentration of Ciprofloxacin can be increased when it is combined with Ranitidine.
CisplatinThe serum concentration of Cisplatin can be increased when it is combined with Ranitidine.
CitalopramThe serum concentration of Citalopram can be increased when it is combined with Ranitidine.
ClarithromycinThe serum concentration of Clarithromycin can be increased when it is combined with Ranitidine.
ClemastineThe metabolism of Ranitidine can be decreased when combined with Clemastine.
ClobazamThe serum concentration of Clobazam can be increased when it is combined with Ranitidine.
ClobazamThe metabolism of Ranitidine can be decreased when combined with Clobazam.
ClofazimineThe serum concentration of Ranitidine can be increased when it is combined with Clofazimine.
ClomifeneThe serum concentration of Clomifene can be increased when it is combined with Ranitidine.
ClomipramineThe serum concentration of Ranitidine can be increased when it is combined with Clomipramine.
ClonidineThe serum concentration of Clonidine can be increased when it is combined with Ranitidine.
ClopidogrelThe serum concentration of Clopidogrel can be increased when it is combined with Ranitidine.
ClotrimazoleThe serum concentration of Ranitidine can be decreased when it is combined with Clotrimazole.
ClozapineThe serum concentration of Clozapine can be increased when it is combined with Ranitidine.
ClozapineThe metabolism of Ranitidine can be decreased when combined with Clozapine.
CobicistatThe serum concentration of Ranitidine can be increased when it is combined with Cobicistat.
CobimetinibThe serum concentration of Cobimetinib can be increased when it is combined with Ranitidine.
CocaineThe metabolism of Ranitidine can be decreased when combined with Cocaine.
ColchicineThe serum concentration of Colchicine can be increased when it is combined with Ranitidine.
ColforsinThe serum concentration of Ranitidine can be increased when it is combined with Colforsin.
Conjugated Equine EstrogensThe serum concentration of Conjugated Equine Estrogens can be increased when it is combined with Ranitidine.
CrizotinibThe serum concentration of Crizotinib can be increased when it is combined with Ranitidine.
CyclophosphamideThe serum concentration of Ranitidine can be increased when it is combined with Cyclophosphamide.
CyclosporineThe serum concentration of Ranitidine can be decreased when it is combined with Cyclosporine.
CyclosporineThe serum concentration of Cyclosporine can be increased when it is combined with Ranitidine.
Cyproterone acetateThe serum concentration of Ranitidine can be decreased when it is combined with Cyproterone acetate.
CysteamineThe therapeutic efficacy of Cysteamine can be decreased when used in combination with Ranitidine.
Dabigatran etexilateThe serum concentration of Dabigatran etexilate can be increased when it is combined with Ranitidine.
DabrafenibThe serum concentration of Ranitidine can be decreased when it is combined with Dabrafenib.
DaclatasvirThe serum concentration of Ranitidine can be increased when it is combined with Daclatasvir.
DactinomycinThe serum concentration of Dactinomycin can be increased when it is combined with Ranitidine.
DapagliflozinThe serum concentration of Dapagliflozin can be increased when it is combined with Ranitidine.
DarifenacinThe metabolism of Ranitidine can be decreased when combined with Darifenacin.
DarunavirThe serum concentration of Ranitidine can be increased when it is combined with Darunavir.
DasatinibRanitidine can cause a decrease in the absorption of Dasatinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
DasatinibThe serum concentration of Ranitidine can be increased when it is combined with Dasatinib.
DaunorubicinThe serum concentration of Ranitidine can be decreased when it is combined with Daunorubicin.
DaunorubicinThe serum concentration of Daunorubicin can be increased when it is combined with Ranitidine.
DebrisoquinThe serum concentration of Debrisoquin can be increased when it is combined with Ranitidine.
DeferasiroxThe serum concentration of Ranitidine can be increased when it is combined with Deferasirox.
DelavirdineThe serum concentration of Delavirdine can be decreased when it is combined with Ranitidine.
DelavirdineThe metabolism of Ranitidine can be decreased when combined with Delavirdine.
DesipramineThe serum concentration of Ranitidine can be increased when it is combined with Desipramine.
DesloratadineThe serum concentration of Ranitidine can be increased when it is combined with Desloratadine.
DexamethasoneThe serum concentration of Ranitidine can be decreased when it is combined with Dexamethasone.
DexamethasoneThe serum concentration of Dexamethasone can be increased when it is combined with Ranitidine.
DexmethylphenidateRanitidine can cause an increase in the absorption of Dexmethylphenidate resulting in an increased serum concentration and potentially a worsening of adverse effects.
DextroamphetamineDextroamphetamine may decrease the sedative activities of Ranitidine.
DextromethorphanThe serum concentration of Ranitidine can be increased when it is combined with Dextromethorphan.
DiazepamThe serum concentration of Diazepam can be increased when it is combined with Ranitidine.
DiclofenacThe serum concentration of Ranitidine can be increased when it is combined with Diclofenac.
DiethylstilbestrolThe serum concentration of Diethylstilbestrol can be increased when it is combined with Ranitidine.
DigitoxinThe serum concentration of Digitoxin can be increased when it is combined with Ranitidine.
DigoxinThe serum concentration of Ranitidine can be decreased when it is combined with Digoxin.
DigoxinThe serum concentration of Digoxin can be increased when it is combined with Ranitidine.
DihydroergotamineThe serum concentration of Ranitidine can be increased when it is combined with Dihydroergotamine.
DihydrotestosteroneThe serum concentration of Dihydrotestosterone can be increased when it is combined with Ranitidine.
DiltiazemThe serum concentration of Diltiazem can be increased when it is combined with Ranitidine.
DiphenhydramineThe metabolism of Ranitidine can be decreased when combined with Diphenhydramine.
DipyridamoleThe serum concentration of Dipyridamole can be increased when it is combined with Ranitidine.
DocetaxelThe serum concentration of Docetaxel can be increased when it is combined with Ranitidine.
DomperidoneThe serum concentration of Domperidone can be increased when it is combined with Ranitidine.
DoxazosinThe serum concentration of Ranitidine can be increased when it is combined with Doxazosin.
DoxepinThe serum concentration of Ranitidine can be increased when it is combined with Doxepin.
DoxofyllineThe serum concentration of Doxofylline can be increased when it is combined with Ranitidine.
DoxorubicinThe serum concentration of Ranitidine can be decreased when it is combined with Doxorubicin.
DoxorubicinThe serum concentration of Doxorubicin can be increased when it is combined with Ranitidine.
DronabinolThe serum concentration of Ranitidine can be increased when it is combined with Dronabinol.
DronedaroneThe serum concentration of Ranitidine can be increased when it is combined with Dronedarone.
DuloxetineThe metabolism of Ranitidine can be decreased when combined with Duloxetine.
EdoxabanThe serum concentration of Edoxaban can be increased when it is combined with Ranitidine.
EfavirenzThe metabolism of Ranitidine can be decreased when combined with Efavirenz.
ElbasvirThe serum concentration of Ranitidine can be increased when it is combined with Elbasvir.
EletriptanThe serum concentration of Eletriptan can be increased when it is combined with Ranitidine.
EliglustatThe metabolism of Ranitidine can be decreased when combined with Eliglustat.
EnalaprilThe serum concentration of Ranitidine can be increased when it is combined with Enalapril.
EnzalutamideThe serum concentration of Ranitidine can be increased when it is combined with Enzalutamide.
EpinastineThe serum concentration of Epinastine can be increased when it is combined with Ranitidine.
ErgonovineThe serum concentration of Ranitidine can be increased when it is combined with Ergonovine.
ErgotamineThe serum concentration of Ranitidine can be increased when it is combined with Ergotamine.
ErlotinibThe serum concentration of Erlotinib can be increased when it is combined with Ranitidine.
ErythromycinThe serum concentration of Ranitidine can be decreased when it is combined with Erythromycin.
ErythromycinThe serum concentration of Erythromycin can be increased when it is combined with Ranitidine.
Eslicarbazepine acetateThe metabolism of Ranitidine can be decreased when combined with Eslicarbazepine acetate.
EsomeprazoleThe metabolism of Ranitidine can be decreased when combined with Esomeprazole.
EstradiolThe serum concentration of Estradiol can be increased when it is combined with Ranitidine.
EstramustineThe serum concentration of Ranitidine can be increased when it is combined with Estramustine.
EstriolThe serum concentration of Ranitidine can be decreased when it is combined with Estriol.
EstriolThe serum concentration of Estriol can be increased when it is combined with Ranitidine.
EstroneThe serum concentration of Ranitidine can be decreased when it is combined with Estrone.
EstroneThe serum concentration of Estrone can be increased when it is combined with Ranitidine.
Ethinyl EstradiolThe serum concentration of Ethinyl Estradiol can be increased when it is combined with Ranitidine.
EtoposideThe serum concentration of Etoposide can be increased when it is combined with Ranitidine.
EtravirineThe serum concentration of Ranitidine can be increased when it is combined with Etravirine.
EverolimusThe serum concentration of Everolimus can be increased when it is combined with Ranitidine.
EzetimibeThe serum concentration of Ezetimibe can be increased when it is combined with Ranitidine.
FelodipineThe serum concentration of Ranitidine can be increased when it is combined with Felodipine.
FentanylThe serum concentration of Ranitidine can be increased when it is combined with Fentanyl.
FesoterodineThe serum concentration of the active metabolites of Fesoterodine can be increased when Fesoterodine is used in combination with Ranitidine.
FexofenadineThe serum concentration of Fexofenadine can be increased when it is combined with Ranitidine.
FidaxomicinThe serum concentration of Fidaxomicin can be increased when it is combined with Ranitidine.
FluconazoleThe serum concentration of Ranitidine can be increased when it is combined with Fluconazole.
FluoxetineThe serum concentration of Ranitidine can be increased when it is combined with Fluoxetine.
FlupentixolThe serum concentration of Ranitidine can be increased when it is combined with Flupentixol.
FluphenazineThe serum concentration of Ranitidine can be increased when it is combined with Fluphenazine.
FlurazepamThe serum concentration of Ranitidine can be increased when it is combined with Flurazepam.
Fluticasone furoateThe serum concentration of Fluticasone furoate can be increased when it is combined with Ranitidine.
FluvoxamineThe serum concentration of Ranitidine can be increased when it is combined with Fluvoxamine.
FosamprenavirThe serum concentration of Fosamprenavir can be decreased when it is combined with Ranitidine.
FosphenytoinThe metabolism of Ranitidine can be increased when combined with Fosphenytoin.
GefitinibThe serum concentration of Gefitinib can be increased when it is combined with Ranitidine.
GemcitabineThe serum concentration of Gemcitabine can be increased when it is combined with Ranitidine.
GemfibrozilThe metabolism of Ranitidine can be decreased when combined with Gemfibrozil.
GenisteinThe serum concentration of Ranitidine can be increased when it is combined with Genistein.
GlibornurideThe serum concentration of Glibornuride can be increased when it is combined with Ranitidine.
GliclazideThe serum concentration of Gliclazide can be increased when it is combined with Ranitidine.
GlimepirideThe serum concentration of Glimepiride can be increased when it is combined with Ranitidine.
GlipizideThe serum concentration of Glipizide can be increased when it is combined with Ranitidine.
GliquidoneThe serum concentration of Gliquidone can be increased when it is combined with Ranitidine.
GlisoxepideThe serum concentration of Glisoxepide can be increased when it is combined with Ranitidine.
GlyburideThe serum concentration of Glyburide can be increased when it is combined with Ranitidine.
GlycerolThe serum concentration of Ranitidine can be increased when it is combined with Glycerol.
Gramicidin DThe serum concentration of Ranitidine can be increased when it is combined with Gramicidin D.
GrazoprevirThe serum concentration of Grazoprevir can be increased when it is combined with Ranitidine.
GrepafloxacinThe serum concentration of Grepafloxacin can be increased when it is combined with Ranitidine.
HaloperidolThe serum concentration of Haloperidol can be increased when it is combined with Ranitidine.
HyaluronidaseThe therapeutic efficacy of Hyaluronidase can be decreased when used in combination with Ranitidine.
HydrocortisoneThe serum concentration of Hydrocortisone can be increased when it is combined with Ranitidine.
Hydroxyamphetamine hydrobromideHydroxyamphetamine hydrobromide may decrease the sedative activities of Ranitidine.
IbuprofenThe serum concentration of Ibuprofen can be increased when it is combined with Ranitidine.
IdelalisibThe serum concentration of Idelalisib can be increased when it is combined with Ranitidine.
ImatinibThe serum concentration of Imatinib can be increased when it is combined with Ranitidine.
ImipramineThe serum concentration of Imipramine can be increased when it is combined with Ranitidine.
IndacaterolThe serum concentration of Indacaterol can be increased when it is combined with Ranitidine.
IndinavirThe serum concentration of Indinavir can be decreased when it is combined with Ranitidine.
IndomethacinThe serum concentration of Indomethacin can be increased when it is combined with Ranitidine.
IrinotecanThe serum concentration of Irinotecan can be increased when it is combined with Ranitidine.
IsavuconazoniumThe serum concentration of Ranitidine can be increased when it is combined with Isavuconazonium.
IsoniazidThe metabolism of Ranitidine can be decreased when combined with Isoniazid.
ItraconazoleThe serum concentration of Itraconazole can be decreased when it is combined with Ranitidine.
ItraconazoleThe serum concentration of Ranitidine can be increased when it is combined with Itraconazole.
IvacaftorThe serum concentration of Ranitidine can be increased when it is combined with Ivacaftor.
IvermectinThe serum concentration of Ivermectin can be increased when it is combined with Ranitidine.
KetamineThe serum concentration of Ranitidine can be increased when it is combined with Ketamine.
KetazolamThe serum concentration of Ketazolam can be increased when it is combined with Ranitidine.
KetoconazoleThe serum concentration of Ranitidine can be increased when it is combined with Ketoconazole.
LamivudineThe serum concentration of Lamivudine can be increased when it is combined with Ranitidine.
LamotrigineThe serum concentration of Lamotrigine can be increased when it is combined with Ranitidine.
LansoprazoleThe serum concentration of Lansoprazole can be increased when it is combined with Ranitidine.
LapatinibThe serum concentration of Ranitidine can be increased when it is combined with Lapatinib.
LedipasvirThe serum concentration of Ledipasvir can be increased when it is combined with Ranitidine.
LenalidomideThe serum concentration of Lenalidomide can be increased when it is combined with Ranitidine.
LenvatinibThe serum concentration of Lenvatinib can be increased when it is combined with Ranitidine.
LevetiracetamThe serum concentration of Levetiracetam can be increased when it is combined with Ranitidine.
LevofloxacinThe serum concentration of Levofloxacin can be increased when it is combined with Ranitidine.
LevomilnacipranThe serum concentration of Levomilnacipran can be increased when it is combined with Ranitidine.
LevothyroxineThe serum concentration of Ranitidine can be decreased when it is combined with Levothyroxine.
LidocaineThe serum concentration of Ranitidine can be increased when it is combined with Lidocaine.
LinagliptinThe serum concentration of Linagliptin can be increased when it is combined with Ranitidine.
LiothyronineThe serum concentration of Ranitidine can be decreased when it is combined with Liothyronine.
LiotrixThe serum concentration of Ranitidine can be decreased when it is combined with Liotrix.
LisdexamfetamineLisdexamfetamine may decrease the sedative activities of Ranitidine.
LisinoprilThe serum concentration of Ranitidine can be increased when it is combined with Lisinopril.
LomitapideThe serum concentration of Ranitidine can be increased when it is combined with Lomitapide.
LoperamideThe serum concentration of Loperamide can be increased when it is combined with Ranitidine.
LopinavirThe serum concentration of Ranitidine can be increased when it is combined with Lopinavir.
LoratadineThe serum concentration of Ranitidine can be increased when it is combined with Loratadine.
LorcaserinThe metabolism of Ranitidine can be decreased when combined with Lorcaserin.
LosartanThe serum concentration of Losartan can be increased when it is combined with Ranitidine.
LovastatinThe serum concentration of Ranitidine can be increased when it is combined with Lovastatin.
LuliconazoleThe serum concentration of Ranitidine can be increased when it is combined with Luliconazole.
LumacaftorThe serum concentration of Ranitidine can be decreased when it is combined with Lumacaftor.
LumefantrineThe metabolism of Ranitidine can be decreased when combined with Lumefantrine.
MannitolThe serum concentration of Mannitol can be increased when it is combined with Ranitidine.
MaprotilineThe serum concentration of Ranitidine can be increased when it is combined with Maprotiline.
MebendazoleThe serum concentration of Ranitidine can be increased when it is combined with Mebendazole.
MefloquineThe serum concentration of Ranitidine can be increased when it is combined with Mefloquine.
Megestrol acetateThe serum concentration of Ranitidine can be increased when it is combined with Megestrol acetate.
MephentermineMephentermine may decrease the sedative activities of Ranitidine.
MeprobamateThe serum concentration of Ranitidine can be increased when it is combined with Meprobamate.
MesalazineThe therapeutic efficacy of Mesalazine can be decreased when used in combination with Ranitidine.
MethadoneThe serum concentration of Ranitidine can be increased when it is combined with Methadone.
MethamphetamineMethamphetamine may decrease the sedative activities of Ranitidine.
MethotrexateThe serum concentration of Methotrexate can be increased when it is combined with Ranitidine.
MethotrimeprazineThe metabolism of Ranitidine can be decreased when combined with Methotrimeprazine.
MethylphenidateRanitidine can cause an increase in the absorption of Methylphenidate resulting in an increased serum concentration and potentially a worsening of adverse effects.
MethylprednisoloneThe serum concentration of Methylprednisolone can be increased when it is combined with Ranitidine.
MetoprololThe serum concentration of Metoprolol can be increased when it is combined with Ranitidine.
MexiletineThe metabolism of Ranitidine can be decreased when combined with Mexiletine.
MibefradilThe serum concentration of Ranitidine can be increased when it is combined with Mibefradil.
MiconazoleThe serum concentration of Ranitidine can be increased when it is combined with Miconazole.
MidazolamThe serum concentration of Ranitidine can be decreased when it is combined with Midazolam.
MidazolamThe serum concentration of Midazolam can be increased when it is combined with Ranitidine.
MifepristoneThe serum concentration of Ranitidine can be decreased when it is combined with Mifepristone.
MirabegronThe serum concentration of Mirabegron can be increased when it is combined with Ranitidine.
MirabegronThe metabolism of Ranitidine can be decreased when combined with Mirabegron.
MitomycinThe serum concentration of Ranitidine can be increased when it is combined with Mitomycin.
MitoxantroneThe serum concentration of Ranitidine can be decreased when it is combined with Mitoxantrone.
MitoxantroneThe serum concentration of Mitoxantrone can be increased when it is combined with Ranitidine.
MoclobemideThe metabolism of Ranitidine can be decreased when combined with Moclobemide.
ModafinilThe metabolism of Ranitidine can be decreased when combined with Modafinil.
MorphineThe serum concentration of Morphine can be increased when it is combined with Ranitidine.
Mycophenolate mofetilThe serum concentration of Mycophenolate mofetil can be increased when it is combined with Ranitidine.
NadololThe serum concentration of Nadolol can be increased when it is combined with Ranitidine.
NaloxegolThe serum concentration of Naloxegol can be increased when it is combined with Ranitidine.
NaloxoneThe serum concentration of Naloxone can be increased when it is combined with Ranitidine.
NaltrexoneThe serum concentration of Ranitidine can be increased when it is combined with Naltrexone.
NaringeninThe serum concentration of Ranitidine can be increased when it is combined with Naringenin.
NefazodoneThe serum concentration of Ranitidine can be decreased when it is combined with Nefazodone.
NelfinavirThe serum concentration of Nelfinavir can be decreased when it is combined with Ranitidine.
NeostigmineThe serum concentration of Ranitidine can be increased when it is combined with Neostigmine.
NevirapineThe metabolism of Ranitidine can be decreased when combined with Nevirapine.
NicardipineThe serum concentration of Ranitidine can be increased when it is combined with Nicardipine.
NifedipineThe serum concentration of Ranitidine can be decreased when it is combined with Nifedipine.
NifedipineThe serum concentration of Nifedipine can be increased when it is combined with Ranitidine.
NilotinibThe serum concentration of Nilotinib can be increased when it is combined with Ranitidine.
NintedanibThe serum concentration of Nintedanib can be increased when it is combined with Ranitidine.
NisoldipineThe serum concentration of Ranitidine can be increased when it is combined with Nisoldipine.
NitrazepamThe serum concentration of Ranitidine can be increased when it is combined with Nitrazepam.
NitrendipineThe serum concentration of Ranitidine can be increased when it is combined with Nitrendipine.
NizatidineThe serum concentration of Nizatidine can be increased when it is combined with Ranitidine.
NorethisteroneThe serum concentration of Ranitidine can be decreased when it is combined with Norethisterone.
OlanzapineThe serum concentration of Olanzapine can be increased when it is combined with Ranitidine.
OmbitasvirThe serum concentration of Ombitasvir can be increased when it is combined with Ranitidine.
OmeprazoleThe serum concentration of Ranitidine can be increased when it is combined with Omeprazole.
OsimertinibThe serum concentration of Osimertinib can be increased when it is combined with Ranitidine.
OsimertinibThe serum concentration of Ranitidine can be decreased when it is combined with Osimertinib.
P-NitrophenolThe serum concentration of Ranitidine can be increased when it is combined with P-Nitrophenol.
PaclitaxelThe serum concentration of Paclitaxel can be increased when it is combined with Ranitidine.
Palmitic AcidThe serum concentration of Ranitidine can be increased when it is combined with Palmitic Acid.
PanobinostatThe serum concentration of Panobinostat can be increased when it is combined with Ranitidine.
PanobinostatThe metabolism of Ranitidine can be decreased when combined with Panobinostat.
PantoprazoleThe serum concentration of Ranitidine can be increased when it is combined with Pantoprazole.
ParoxetineThe serum concentration of Ranitidine can be increased when it is combined with Paroxetine.
PazopanibThe serum concentration of Pazopanib can be increased when it is combined with Ranitidine.
Peginterferon alfa-2bThe serum concentration of Ranitidine can be decreased when it is combined with Peginterferon alfa-2b.
PerindoprilThe serum concentration of Ranitidine can be increased when it is combined with Perindopril.
PhenobarbitalThe serum concentration of Ranitidine can be decreased when it is combined with Phenobarbital.
PhenobarbitalThe serum concentration of Phenobarbital can be increased when it is combined with Ranitidine.
PhenterminePhentermine may decrease the sedative activities of Ranitidine.
PhenytoinThe serum concentration of Phenytoin can be increased when it is combined with Ranitidine.
PhenytoinThe metabolism of Ranitidine can be increased when combined with Phenytoin.
PimozideThe serum concentration of Ranitidine can be increased when it is combined with Pimozide.
PitavastatinThe serum concentration of Pitavastatin can be increased when it is combined with Ranitidine.
Platelet Activating FactorThe serum concentration of Ranitidine can be decreased when it is combined with Platelet Activating Factor.
PomalidomideThe serum concentration of Pomalidomide can be increased when it is combined with Ranitidine.
PonatinibThe serum concentration of Ponatinib can be increased when it is combined with Ranitidine.
PosaconazoleThe serum concentration of Posaconazole can be decreased when it is combined with Ranitidine.
PosaconazoleThe serum concentration of Ranitidine can be increased when it is combined with Posaconazole.
PrasugrelThe serum concentration of the active metabolites of Prasugrel can be reduced when Prasugrel is used in combination with Ranitidine resulting in a loss in efficacy.
PravastatinThe serum concentration of Pravastatin can be increased when it is combined with Ranitidine.
PrazosinThe serum concentration of Prazosin can be increased when it is combined with Ranitidine.
PrednisoloneThe serum concentration of Prednisolone can be increased when it is combined with Ranitidine.
PrednisoneThe serum concentration of Prednisone can be increased when it is combined with Ranitidine.
PrimidoneThe metabolism of Ranitidine can be increased when combined with Primidone.
ProbenecidThe serum concentration of Ranitidine can be increased when it is combined with Probenecid.
ProcainamideThe serum concentration of Procainamide can be increased when it is combined with Ranitidine.
ProgesteroneThe serum concentration of Ranitidine can be decreased when it is combined with Progesterone.
ProgesteroneThe serum concentration of Progesterone can be increased when it is combined with Ranitidine.
PromazineThe metabolism of Ranitidine can be decreased when combined with Promazine.
PromethazineThe serum concentration of Ranitidine can be increased when it is combined with Promethazine.
PropafenoneThe serum concentration of Ranitidine can be increased when it is combined with Propafenone.
PropranololThe serum concentration of Propranolol can be increased when it is combined with Ranitidine.
ProtriptylineThe serum concentration of Ranitidine can be increased when it is combined with Protriptyline.
PrucaloprideThe serum concentration of Prucalopride can be increased when it is combined with Ranitidine.
QuercetinThe serum concentration of Ranitidine can be increased when it is combined with Quercetin.
QuetiapineThe serum concentration of Quetiapine can be increased when it is combined with Ranitidine.
QuinacrineThe serum concentration of Ranitidine can be increased when it is combined with Quinacrine.
QuinidineThe serum concentration of Ranitidine can be increased when it is combined with Quinidine.
QuinineThe serum concentration of Quinine can be increased when it is combined with Ranitidine.
RanolazineThe serum concentration of Ranolazine can be increased when it is combined with Ranitidine.
ReboxetineThe serum concentration of Ranitidine can be increased when it is combined with Reboxetine.
RegorafenibThe serum concentration of Ranitidine can be increased when it is combined with Regorafenib.
ReserpineThe serum concentration of Ranitidine can be decreased when it is combined with Reserpine.
ReserpineThe serum concentration of Reserpine can be increased when it is combined with Ranitidine.
RifampicinThe serum concentration of Ranitidine can be decreased when it is combined with Rifampicin.
RifampicinThe serum concentration of Rifampicin can be increased when it is combined with Ranitidine.
RifaximinThe serum concentration of Rifaximin can be increased when it is combined with Ranitidine.
RilpivirineThe serum concentration of Rilpivirine can be decreased when it is combined with Ranitidine.
RilpivirineThe serum concentration of Ranitidine can be increased when it is combined with Rilpivirine.
RisedronateThe serum concentration of Risedronate can be increased when it is combined with Ranitidine.
RisperidoneThe serum concentration of Risperidone can be increased when it is combined with Ranitidine.
RitonavirThe serum concentration of Ranitidine can be decreased when it is combined with Ritonavir.
RitonavirThe serum concentration of Ritonavir can be increased when it is combined with Ranitidine.
RivaroxabanThe serum concentration of Rivaroxaban can be increased when it is combined with Ranitidine.
RolapitantThe serum concentration of Ranitidine can be increased when it is combined with Rolapitant.
RomidepsinThe serum concentration of Romidepsin can be increased when it is combined with Ranitidine.
RopiniroleThe metabolism of Ranitidine can be decreased when combined with Ropinirole.
Salicylic acidThe serum concentration of Salicylic acid can be increased when it is combined with Ranitidine.
SaquinavirThe serum concentration of Saquinavir can be increased when it is combined with Ranitidine.
SaquinavirThe serum concentration of Ranitidine can be decreased when it is combined with Saquinavir.
ScopolamineThe serum concentration of Ranitidine can be increased when it is combined with Scopolamine.
SelegilineThe serum concentration of Ranitidine can be increased when it is combined with Selegiline.
SelexipagThe serum concentration of Selexipag can be increased when it is combined with Ranitidine.
SertralineThe serum concentration of Ranitidine can be increased when it is combined with Sertraline.
SilodosinThe serum concentration of Silodosin can be increased when it is combined with Ranitidine.
SimeprevirThe serum concentration of Simeprevir can be increased when it is combined with Ranitidine.
SimvastatinThe serum concentration of Ranitidine can be increased when it is combined with Simvastatin.
SirolimusThe serum concentration of Ranitidine can be decreased when it is combined with Sirolimus.
SitagliptinThe serum concentration of Sitagliptin can be increased when it is combined with Ranitidine.
SofosbuvirThe serum concentration of Sofosbuvir can be increased when it is combined with Ranitidine.
SorafenibThe serum concentration of Sorafenib can be increased when it is combined with Ranitidine.
SparfloxacinThe serum concentration of Sparfloxacin can be increased when it is combined with Ranitidine.
SphingosineThe serum concentration of Sphingosine can be increased when it is combined with Ranitidine.
SpironolactoneThe serum concentration of Ranitidine can be increased when it is combined with Spironolactone.
St. John's WortThe serum concentration of Ranitidine can be decreased when it is combined with St. John's Wort.
StaurosporineThe serum concentration of Ranitidine can be increased when it is combined with Staurosporine.
StiripentolThe metabolism of Ranitidine can be decreased when combined with Stiripentol.
StreptozocinThe serum concentration of Ranitidine can be decreased when it is combined with Streptozocin.
SulfinpyrazoneThe serum concentration of Ranitidine can be increased when it is combined with Sulfinpyrazone.
SumatriptanThe serum concentration of Ranitidine can be increased when it is combined with Sumatriptan.
SunitinibThe serum concentration of Ranitidine can be increased when it is combined with Sunitinib.
TacrineThe serum concentration of Ranitidine can be increased when it is combined with Tacrine.
TacrolimusThe serum concentration of Ranitidine can be decreased when it is combined with Tacrolimus.
TacrolimusThe serum concentration of Tacrolimus can be increased when it is combined with Ranitidine.
TamoxifenThe serum concentration of Ranitidine can be decreased when it is combined with Tamoxifen.
TamoxifenThe serum concentration of Tamoxifen can be increased when it is combined with Ranitidine.
Taurocholic AcidThe serum concentration of Taurocholic Acid can be increased when it is combined with Ranitidine.
Technetium Tc-99m sestamibiThe serum concentration of Technetium Tc-99m sestamibi can be increased when it is combined with Ranitidine.
TelaprevirThe serum concentration of Telaprevir can be increased when it is combined with Ranitidine.
TelmisartanThe serum concentration of Ranitidine can be increased when it is combined with Telmisartan.
TemsirolimusThe serum concentration of Temsirolimus can be increased when it is combined with Ranitidine.
TenofovirThe metabolism of Ranitidine can be decreased when combined with Tenofovir.
TerazosinThe serum concentration of Ranitidine can be increased when it is combined with Terazosin.
TerbinafineThe metabolism of Ranitidine can be decreased when combined with Terbinafine.
TerfenadineThe serum concentration of Ranitidine can be increased when it is combined with Terfenadine.
TeriflunomideThe serum concentration of Ranitidine can be decreased when it is combined with Teriflunomide.
TesmilifeneThe serum concentration of Ranitidine can be decreased when it is combined with Tesmilifene.
TestosteroneThe serum concentration of Ranitidine can be increased when it is combined with Testosterone.
TheophyllineThe metabolism of Ranitidine can be decreased when combined with Theophylline.
ThioridazineThe serum concentration of Thioridazine can be increased when it is combined with Ranitidine.
ThioridazineThe metabolism of Ranitidine can be decreased when combined with Thioridazine.
TicagrelorThe serum concentration of Ticagrelor can be increased when it is combined with Ranitidine.
TiclopidineThe metabolism of Ranitidine can be decreased when combined with Ticlopidine.
TimololThe serum concentration of Timolol can be increased when it is combined with Ranitidine.
TipranavirThe metabolism of Ranitidine can be decreased when combined with Tipranavir.
TolazamideThe serum concentration of Tolazamide can be increased when it is combined with Ranitidine.
TolbutamideThe serum concentration of Tolbutamide can be increased when it is combined with Ranitidine.
TolvaptanThe serum concentration of Tolvaptan can be increased when it is combined with Ranitidine.
TopiramateThe metabolism of Ranitidine can be decreased when combined with Topiramate.
TopotecanThe serum concentration of Topotecan can be increased when it is combined with Ranitidine.
ToremifeneThe serum concentration of Toremifene can be increased when it is combined with Ranitidine.
TranylcypromineThe metabolism of Ranitidine can be decreased when combined with Tranylcypromine.
Trastuzumab emtansineThe serum concentration of Trastuzumab emtansine can be increased when it is combined with Ranitidine.
TrazodoneThe serum concentration of Ranitidine can be decreased when it is combined with Trazodone.
TrifluoperazineThe serum concentration of Ranitidine can be increased when it is combined with Trifluoperazine.
TriflupromazineThe serum concentration of Ranitidine can be increased when it is combined with Triflupromazine.
TrimethoprimThe serum concentration of Ranitidine can be decreased when it is combined with Trimethoprim.
TrimipramineThe serum concentration of Ranitidine can be increased when it is combined with Trimipramine.
TroleandomycinThe serum concentration of Ranitidine can be increased when it is combined with Troleandomycin.
UlipristalThe serum concentration of Ulipristal can be increased when it is combined with Ranitidine.
UmeclidiniumThe serum concentration of Umeclidinium can be increased when it is combined with Ranitidine.
VareniclineThe serum concentration of Varenicline can be increased when it is combined with Ranitidine.
VecuroniumThe serum concentration of Vecuronium can be increased when it is combined with Ranitidine.
VemurafenibThe serum concentration of Ranitidine can be increased when it is combined with Vemurafenib.
VenlafaxineThe serum concentration of Venlafaxine can be increased when it is combined with Ranitidine.
VerapamilThe serum concentration of Ranitidine can be decreased when it is combined with Verapamil.
VerapamilThe serum concentration of Verapamil can be increased when it is combined with Ranitidine.
VinblastineThe serum concentration of Ranitidine can be decreased when it is combined with Vinblastine.
VinblastineThe serum concentration of Vinblastine can be increased when it is combined with Ranitidine.
VincristineThe serum concentration of Vincristine can be increased when it is combined with Ranitidine.
VincristineThe serum concentration of Ranitidine can be decreased when it is combined with Vincristine.
VinorelbineThe serum concentration of Ranitidine can be increased when it is combined with Vinorelbine.
VismodegibThe serum concentration of Vismodegib can be increased when it is combined with Ranitidine.
VoriconazoleThe metabolism of Ranitidine can be decreased when combined with Voriconazole.
WarfarinThe serum concentration of Warfarin can be increased when it is combined with Ranitidine.
ZidovudineThe serum concentration of Zidovudine can be increased when it is combined with Ranitidine.
ZimelidineThe serum concentration of Ranitidine can be increased when it is combined with Zimelidine.
ZiprasidoneThe metabolism of Ranitidine can be decreased when combined with Ziprasidone.
Food Interactions
  • Avoid alcohol.
  • Avoid excessive quantities of coffee or tea (Caffeine).
  • Avoid milk, calcium containing dairy products, iron, antacids, or aluminum salts 2 hours before or 6 hours after using antacids while on this medication.
  • Take without regard to meals.

Targets

Kind
Protein
Organism
Human
Pharmacological action
yes
Actions
antagonist
General Function:
Histamine receptor activity
Specific Function:
The H2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) si...
Gene Name:
HRH2
Uniprot ID:
P25021
Molecular Weight:
40097.65 Da
References
  1. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
  2. Pattichis K, Louca LL: Histamine, histamine H2-receptor antagonists, gastric acid secretion and ulcers: an overview. Drug Metabol Drug Interact. 1995;12(1):1-36. [PubMed:7554999 ]

Enzymes

Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrateinhibitor
General Function:
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
Specific Function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N...
Gene Name:
CYP1A2
Uniprot ID:
P05177
Molecular Weight:
58293.76 Da
References
  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Steroid hydroxylase activity
Specific Function:
Responsible for the metabolism of a number of therapeutic agents such as the anticonvulsant drug S-mephenytoin, omeprazole, proguanil, certain barbiturates, diazepam, propranolol, citalopram and imipramine.
Gene Name:
CYP2C19
Uniprot ID:
P33261
Molecular Weight:
55930.545 Da
References
  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrateinhibitor
General Function:
Steroid hydroxylase activity
Specific Function:
Responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It is involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants.
Gene Name:
CYP2D6
Uniprot ID:
P10635
Molecular Weight:
55768.94 Da
References
  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
  2. Drug Interactions: Cytochrome P450 Drug Interaction Table [Link]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
inhibitor
General Function:
Vitamin d3 25-hydroxylase activity
Specific Function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiot...
Gene Name:
CYP3A4
Uniprot ID:
P08684
Molecular Weight:
57342.67 Da
References
  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
inhibitor
General Function:
Oxygen binding
Specific Function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Gene Name:
CYP3A5
Uniprot ID:
P20815
Molecular Weight:
57108.065 Da
References
  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]

Transporters

Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
inhibitor
General Function:
Secondary active organic cation transmembrane transporter activity
Specific Function:
Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1-methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), N-1-methylnicotinamide (NMN), 4-(4-(dimethylamino)styryl)-N-methylpyridinium (ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drugs quinine...
Gene Name:
SLC22A1
Uniprot ID:
O15245
Molecular Weight:
61153.345 Da
References
  1. Bednarczyk D, Ekins S, Wikel JH, Wright SH: Influence of molecular structure on substrate binding to the human organic cation transporter, hOCT1. Mol Pharmacol. 2003 Mar;63(3):489-98. [PubMed:12606755 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrateinhibitor
General Function:
Xenobiotic-transporting atpase activity
Specific Function:
Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
Gene Name:
ABCB1
Uniprot ID:
P08183
Molecular Weight:
141477.255 Da
References
  1. Lentz KA, Polli JW, Wring SA, Humphreys JE, Polli JE: Influence of passive permeability on apparent P-glycoprotein kinetics. Pharm Res. 2000 Dec;17(12):1456-60. [PubMed:11303953 ]
  2. Schwab D, Fischer H, Tabatabaei A, Poli S, Huwyler J: Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery. J Med Chem. 2003 Apr 24;46(9):1716-25. [PubMed:12699389 ]
  3. Troutman MD, Thakker DR: Novel experimental parameters to quantify the modulation of absorptive and secretory transport of compounds by P-glycoprotein in cell culture models of intestinal epithelium. Pharm Res. 2003 Aug;20(8):1210-24. [PubMed:12948019 ]
  4. Faassen F, Vogel G, Spanings H, Vromans H: Caco-2 permeability, P-glycoprotein transport ratios and brain penetration of heterocyclic drugs. Int J Pharm. 2003 Sep 16;263(1-2):113-22. [PubMed:12954186 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Sodium-independent organic anion transmembrane transporter activity
Specific Function:
Plays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney. Involved in the transport basolateral of steviol, fexofenadine. Transports benzylpenicillin (PCG), estrone-3-sulfate (E1S), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), p-amino-hippurate (PAH), acyclovir (ACV) and ochratoxin (OTA).
Gene Name:
SLC22A8
Uniprot ID:
Q8TCC7
Molecular Weight:
59855.585 Da
References
  1. Tahara H, Kusuhara H, Chida M, Fuse E, Sugiyama Y: Is the monkey an appropriate animal model to examine drug-drug interactions involving renal clearance? Effect of probenecid on the renal elimination of H2 receptor antagonists. J Pharmacol Exp Ther. 2006 Mar;316(3):1187-94. Epub 2005 Nov 16. [PubMed:16291876 ]
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Drug created on June 13, 2005 07:24 / Updated on August 17, 2016 12:23