Showing BioInteractions for Edetic acid (DB00974)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
Interacting Group | Interacting Drugs | |
---|---|---|
Edetic acid is a Adenosine deaminase inhibitor | ||
1 | Adenosine deaminase inhibitors | Dipyridamole, Edetate calcium disodium anhydrous, Edetate disodium anhydrous, Erdosteine, Pentostatin, Theophylline |
2 | Adenosine deaminase substrates | Adenosine, Nelarabine, Vidarabine |
3 | Adenosine deaminase inducers | Theophylline |
Interacting Group | Interacting Drugs | |
---|---|---|
Edetic acid is a Serum paraoxonase/lactonase 3 inhibitor | ||
1 | Serum paraoxonase/lactonase 3 substrates | Lovastatin |
2 | Serum paraoxonase/lactonase 3 inhibitors | Edetate calcium disodium anhydrous, Edetate disodium anhydrous |
Interacting Group | Interacting Drugs | |
---|---|---|
Edetic acid is a Cytochrome P450 19A1 substrate | ||
1 | Cytochrome P450 19A1 inhibitors | Aminoglutethimide, Anastrozole, Betamethasone, Bifonazole, Carbimazole, Cyproterone acetate, Danazol, Diethylstilbestrol, Drostanolone, Econazole, Etretinate, Exemestane, Ketoconazole, Letrozole, Mefloquine, Melatonin, Miconazole, Naringenin, Nicotine, Norgestrel, Paclitaxel, Raloxifene, Sar9, Met (O2)11-Substance P, Tamoxifen, Testolactone, Tioconazole, Troglitazone |
2 | Cytochrome P450 19A1 antagonists | Letrozole |
3 | Cytochrome P450 19A1 substrates | Betamethasone, Endostatin, Methadone, Methyltestosterone, Stanolone, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate |
4 | Cytochrome P450 19A1 inducers | Buserelin, Chlorotrianisene, Chlorphenesin, Methyltestosterone, Nandrolone decanoate, Prasterone sulfate, Sulfathiazole |
5 | Cytochrome P450 19A1 modulators | Edetate calcium disodium anhydrous, Edetate disodium anhydrous |