Showing BioInteractions for Gabapentin (DB00996)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
Interacting Group | Interacting Drugs | |
---|---|---|
Gabapentin is a Adenosine receptor A1 agonist | ||
1 | Adenosine receptor A1 antagonists | Aminophylline, Caffeine, Dyphylline, Istradefylline, Naxifylline, Oxtriphylline, Theobromine, Theophylline |
2 | Adenosine receptor A1 agonists | Adenosine |
3 | Adenosine receptor A1 inhibitors | Enprofylline, Lamotrigine |
4 | Adenosine receptor A1 activators | Cannabidiol |
5 | Adenosine receptor A1 stimulators | Tramadol |
Interacting Group | Interacting Drugs | |
---|---|---|
Gabapentin is a Voltage-dependent calcium channel subunit alpha-2/delta-1 inhibitor | ||
1 | Voltage-dependent calcium channel subunit alpha-2/delta-1 inhibitors | Cyclandelate, Felodipine, Isradipine, Nicardipine, Nilvadipine, Nisoldipine, Nitrendipine |
2 | Voltage-dependent calcium channel subunit alpha-2/delta-1 activators | Ibutilide |
Interacting Group | Interacting Drugs | |
---|---|---|
Gabapentin is a Voltage-dependent calcium channel subunit alpha-2/delta-2 inhibitor | ||
1 | Voltage-dependent calcium channel subunit alpha-2/delta-2 inhibitors | Bepridil, Felodipine, Isradipine, Nitrendipine |
Interacting Group | Interacting Drugs | |
---|---|---|
Gabapentin is a Voltage-dependent N-type calcium channel inhibitor | ||
1 | Voltage-dependent N-type calcium channel inhibitors | Amlodipine |
Interacting Group | Interacting Drugs | |
---|---|---|
Gabapentin is a Potassium voltage-gated channel subfamily KQT member 3 activator | ||
1 | Potassium voltage-gated channel subfamily KQT member 3 inhibitors | Amitriptyline |
2 | Potassium voltage-gated channel subfamily KQT member 3 agonists | Diclofenac |
Interacting Group | Interacting Drugs | |
---|---|---|
Gabapentin is a Potassium voltage-gated channel subfamily KQT member 5 activator |
Interacting Group | Interacting Drugs | |
---|---|---|
Gabapentin is a Branched-chain-amino-acid aminotransferase, cytosolic inhibitor | ||
1 | Branched-chain-amino-acid aminotransferase, cytosolic cofactors | Pyridoxal phosphate |
2 | Branched-chain-amino-acid aminotransferase, cytosolic substrates | Valine |
Interacting Group | Interacting Drugs | |
---|---|---|
Gabapentin is a Large neutral amino acids transporter small subunit 1 substrate | ||
1 | Large neutral amino acids transporter small subunit 1 substrates | L-Glutamine, Thyroid, porcine |