Showing BioInteractions for Gabapentin (DB00996)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
Interacting GroupInteracting Drugs
Gabapentin is a Adenosine receptor A1 agonist
1Adenosine receptor A1 antagonistsAminophylline, Caffeine, Dyphylline, Istradefylline, Naxifylline, Oxtriphylline, Theobromine, Theophylline
2Adenosine receptor A1 agonistsAdenosine
3Adenosine receptor A1 inhibitorsEnprofylline, Lamotrigine
4Adenosine receptor A1 activatorsCannabidiol
5Adenosine receptor A1 stimulatorsTramadol
Interacting GroupInteracting Drugs
Gabapentin is a Voltage-dependent calcium channel subunit alpha-2/delta-1 inhibitor
1Voltage-dependent calcium channel subunit alpha-2/delta-1 inhibitorsCyclandelate, Felodipine, Isradipine, Nicardipine, Nilvadipine, Nisoldipine, Nitrendipine
2Voltage-dependent calcium channel subunit alpha-2/delta-1 activatorsIbutilide
Interacting GroupInteracting Drugs
Gabapentin is a Voltage-dependent calcium channel subunit alpha-2/delta-2 inhibitor
1Voltage-dependent calcium channel subunit alpha-2/delta-2 inhibitorsBepridil, Felodipine, Isradipine, Nitrendipine
Interacting GroupInteracting Drugs
Gabapentin is a Voltage-dependent N-type calcium channel inhibitor
1Voltage-dependent N-type calcium channel inhibitorsAmlodipine
Interacting GroupInteracting Drugs
Gabapentin is a Potassium voltage-gated channel subfamily KQT member 3 activator
1Potassium voltage-gated channel subfamily KQT member 3 inhibitorsAmitriptyline
2Potassium voltage-gated channel subfamily KQT member 3 agonistsDiclofenac
Interacting GroupInteracting Drugs
Gabapentin is a Potassium voltage-gated channel subfamily KQT member 5 activator
Interacting GroupInteracting Drugs
Gabapentin is a Branched-chain-amino-acid aminotransferase, cytosolic inhibitor
1Branched-chain-amino-acid aminotransferase, cytosolic cofactorsPyridoxal phosphate
2Branched-chain-amino-acid aminotransferase, cytosolic substratesValine
Interacting GroupInteracting Drugs
Gabapentin is a Large neutral amino acids transporter small subunit 1 substrate
1Large neutral amino acids transporter small subunit 1 substratesL-Glutamine, Thyroid, porcine