Showing BioInteractions for Trichlormethiazide (DB01021)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Trichlormethiazide is a Solute carrier family 12 member 3 inhibitor | ||
| 1 | Solute carrier family 12 member 3 inhibitors | Bendroflumethiazide, Benzthiazide, Chlorothiazide, Hydrochlorothiazide, Indapamide, Metolazone, Polythiazide, Quinethazone |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Trichlormethiazide is a Sodium/potassium-transporting ATPase subunit alpha-1 inhibitor | ||
| 1 | Sodium/potassium-transporting ATPase subunit alpha-1 inhibitors | Acetyldigitoxin, Bepridil, Bretylium, Deslanoside, Digitoxin, Digoxin, Etacrynic acid, Ouabain |
| 2 | Sodium/potassium-transporting ATPase subunit alpha-1 inducers | Hydroflumethiazide, Magnesium gluconate |
| 3 | Sodium/potassium-transporting ATPase subunit alpha-1 binders | Almitrine, Aluminium, Ciclopirox |
| 4 | Sodium/potassium-transporting ATPase subunit alpha-1 substrates | Potassium, Potassium gluconate, Rubidium Rb-82 |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Trichlormethiazide is a Carbonic anhydrase 4 inhibitor | ||
| 1 | Carbonic anhydrase 4 inhibitors | Acetazolamide, Bendroflumethiazide, Benzthiazide, Brinzolamide, Diclofenamide, Dorzolamide, Ellagic acid, Ethoxzolamide, Hydroflumethiazide, Methazolamide, Methyclothiazide, Sodium carbonate, Topiramate, Zonisamide |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Trichlormethiazide is a Carbonic anhydrase 2 inhibitor | ||
| 1 | Carbonic anhydrase 2 inhibitors | Acetazolamide, Bendroflumethiazide, Benzthiazide, Brinzolamide, Celecoxib, Chlorothiazide, Cyclothiazide, Diazoxide, Diclofenamide, Dorzolamide, Ellagic acid, Ethinamate, Ethoxzolamide, Furosemide, Hydroflumethiazide, Methazolamide, Methyclothiazide, Quinethazone, Sodium carbonate, Sodium sulfate, Sulpiride, Topiramate, Valdecoxib, Zonisamide |
| 2 | Carbonic anhydrase 2 cofactors | Zinc chloride, Zinc sulfate, unspecified form |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Trichlormethiazide is a Carbonic anhydrase 1 inhibitor | ||
| 1 | Carbonic anhydrase 1 inhibitors | Acetazolamide, Amlodipine, Bendroflumethiazide, Benzthiazide, Brinzolamide, Chlorothiazide, Chlorthalidone, Cyclothiazide, Diazoxide, Diclofenamide, Dorzolamide, Ellagic acid, Ethinamate, Ethoxzolamide, Hydroflumethiazide, Methazolamide, Methocarbamol, Methyclothiazide, Quinethazone, Sodium carbonate, Sodium sulfate, Topiramate, Zonisamide |
| 2 | Carbonic anhydrase 1 substrates | Zinc |
| 3 | Carbonic anhydrase 1 ligands | Zinc acetate |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Trichlormethiazide is a Thiopurine S-methyltransferase inhibitor | ||
| 1 | Thiopurine S-methyltransferase substrates | Azathioprine, Cefazolin, Mercaptopurine |
| 2 | Thiopurine S-methyltransferase inhibitors | Bendroflumethiazide, Olsalazine |