1202
  Mrv0541 02231215192D          

 12 12  0  0  1  0            999 V2000
    4.5311    0.7543    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.6500   -0.3006    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.0791    0.5244    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    2.3645   -1.5382    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    2.4115    1.0093    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.0791   -0.3006    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    2.6666    1.7939    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4916    1.7939    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.7465    1.0093    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.7935   -0.7132    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3645   -0.7132    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.7935   -1.5382    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  9  2  0  0  0  0
  2 11  2  0  0  0  0
  3  5  1  0  0  0  0
  3  6  1  0  0  0  0
  3  9  1  0  0  0  0
  4 11  1  0  0  0  0
  5  7  1  0  0  0  0
  6 10  1  6  0  0  0
  6 11  1  0  0  0  0
  7  8  1  0  0  0  0
  8  9  1  0  0  0  0
 10 12  1  0  0  0  0
M  END
> <DRUGBANK_ID>
DB01202

> <DRUG_GROUPS>
approved; investigational

> <GENERIC_NAME>
Levetiracetam

> <SYNONYMS>
Levetiracetam [INN]; Levetiracetamum [INN-Latin]; Levitiracetam

> <BRANDS>
Keppra

> <CHEMICAL_FORMULA>
C8H14N2O2

> <MOLECULAR_WEIGHT>
170.209

> <EXACT_MASS>
170.105527702

> <IUPAC_NAME>
(2R)-2-(2-oxopyrrolidin-1-yl)butanamide

> <INCHI_IDENTIFIER>
InChI=1S/C8H14N2O2/c1-2-6(8(9)12)10-5-3-4-7(10)11/h6H,2-5H2,1H3,(H2,9,12)/t6-/m1/s1

> <INCHI_KEY>
InChIKey=HPHUVLMMVZITSG-ZCFIWIBFSA-N

> <SMILES>
CC[C@@H](N1CCCC1=O)C(N)=O

> <JCHEM_ACCEPTOR_COUNT>
2

> <JCHEM_DONOR_COUNT>
1

> <ALOGPS_LOGP>
-0.64

> <JCHEM_LOGP>
-0.59

> <ALOGPS_LOGS>
0.24

> <JCHEM_POLARIZABILITY>
17.78

> <JCHEM_POLAR_SURFACE_AREA>
63.4

> <JCHEM_REFRACTIVITY>
44.08

> <JCHEM_ROTATABLE_BOND_COUNT>
3

> <ALOGPS_SOLUBILITY>
2.98e+02 g/l

$$$$