Showing BioInteractions for Ephedra sinica root (DB01363)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Ephedra sinica root is a Sodium-dependent dopamine transporter negative modulator | ||
| 1 | Sodium-dependent dopamine transporter inhibitors | 4-Methoxyamphetamine, Armodafinil, Benzatropine, Benzphetamine, Bupropion, Chloroprocaine, Chlorpheniramine, Cocaine, Desvenlafaxine, Dexmethylphenidate, Diethylpropion, Diphenylpyraline, Duloxetine, Escitalopram, Etoperidone, Fencamfamin, Imipramine, Mazindol, Meperidine, Methylphenidate, Modafinil, Nefazodone, Phenmetrazine, Phentermine, Procaine, Pseudoephedrine, Sertraline, Sibutramine, Trimipramine, Venlafaxine |
| 2 | Sodium-dependent dopamine transporter negative modulators | Amphetamine, Dextroamphetamine, Metamfetamine, Midomafetamine, MMDA |
| 3 | Sodium-dependent dopamine transporter binders | Amoxapine, Loxapine, Mianserin, Sertraline |
| 4 | Sodium-dependent dopamine transporter inducers | Dopamine |
| 5 | Sodium-dependent dopamine transporter antagonists | Armodafinil |
| 6 | Sodium-dependent dopamine transporter modulators | Aripiprazole |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Ephedra sinica root is a Synaptic vesicular amine transporter inhibitor | ||
| 1 | Synaptic vesicular amine transporter inhibitors | 4-Methoxyamphetamine, Amphetamine, Deserpidine, Deutetrabenazine, Ephedrine, Isometheptene, Metamfetamine, Midomafetamine, MMDA, Rauwolfia serpentina root, Reserpine, Tetrabenazine |
| 2 | Synaptic vesicular amine transporter inducers | Apomorphine, Benzphetamine, Dextroamphetamine |
| 3 | Synaptic vesicular amine transporter binders | Norepinephrine |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Ephedra sinica root is a Chromaffin granule amine transporter inhibitor | ||
| 1 | Chromaffin granule amine transporter inhibitors | Metamfetamine, MMDA, Reserpine |
| 2 | Chromaffin granule amine transporter binders | Norepinephrine |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Ephedra sinica root is a Amine oxidase [flavin-containing] B inhibitor | ||
| 1 | Amine oxidase [flavin-containing] B antagonists | Moclobemide, Phenelzine, Phentermine, Safinamide |
| 2 | Amine oxidase [flavin-containing] B inhibitors | 4-Methoxyamphetamine, Amantadine, Amphetamine, Farnesol, Furazolidone, Iproniazid, Isatin, Isocarboxazid, Linezolid, Metamfetamine, MMDA, Moclobemide, N-Propargyl-1(S)-Aminoindan, Nandrolone decanoate, Nicotine, Ozanimod, Pargyline, Pioglitazone, Rasagiline, Selegiline, Tedizolid, Tedizolid phosphate, Tranylcypromine, Zimelidine, Zonisamide |
| 3 | Amine oxidase [flavin-containing] B ligands | 5-Hydroxy-N-Propargyl-1(R)-Aminoindan, Dodecyldimethylamine N-oxide |
| 4 | Amine oxidase [flavin-containing] B substrates | Bicifadine, Dopamine, Ozanimod, Phenelzine, Phenylephrine, Sertraline |
| 5 | Amine oxidase [flavin-containing] B binders | Flortaucipir F-18 |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Ephedra sinica root is a Alpha-2B adrenergic receptor agonist | ||
| 1 | Alpha-2B adrenergic receptor antagonists | Aripiprazole, Asenapine, Cabergoline, Carvedilol, Celiprolol, Clozapine, Dronedarone, Fenoldopam, Methotrimeprazine, Mianserin, Paliperidone, Phenoxybenzamine, Pizotifen, Quetiapine, Risperidone, Rotigotine, Yohimbine, Ziprasidone |
| 2 | Alpha-2B adrenergic receptor agonists | Apomorphine, Apraclonidine, Brimonidine, Bromocriptine, Clonidine, Droxidopa, Epinephrine, Etomidate, Metamfetamine, Norepinephrine, Oxymetazoline, Racepinephrine, Xylometazoline |
| 3 | Alpha-2B adrenergic receptor ligands | Aripiprazole |
| 4 | Alpha-2B adrenergic receptor binders | Guanabenz, Guanfacine, Loxapine, Prazosin, Tolazoline |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Ephedra sinica root is a Alpha-2C adrenergic receptor agonist | ||
| 1 | Alpha-2C adrenergic receptor antagonists | Aripiprazole, Asenapine, Brexpiprazole, Cabergoline, Carvedilol, Celiprolol, Clozapine, Dronedarone, Fenoldopam, Iloperidone, Lurasidone, Methotrimeprazine, Mianserin, Phenoxybenzamine, Pizotifen, Quetiapine, Risperidone, Yohimbine, Ziprasidone |
| 2 | Alpha-2C adrenergic receptor agonists | Agmatine, Apomorphine, Brimonidine, Bromocriptine, Clonidine, Droxidopa, Metamfetamine, Norepinephrine, Oxymetazoline, Paliperidone, Racepinephrine, Xylometazoline |
| 3 | Alpha-2C adrenergic receptor binders | Loxapine, Tolazoline |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Ephedra sinica root is a Beta-3 adrenergic receptor agonist | ||
| 1 | Beta-3 adrenergic receptor agonists | Arbutamine, Celiprolol, Clenbuterol, Droxidopa, Fenoterol, Formoterol, Isoprenaline, Mirabegron, Nebivolol, Norepinephrine, Pindolol, Racepinephrine, Solabegron, Terbutaline, Vibegron |
| 2 | Beta-3 adrenergic receptor antagonists | Alprenolol, Bupranolol, Propranolol |
| 3 | Beta-3 adrenergic receptor inverse agonists | Salmeterol |