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Showing drug card for Sulfamethazine (DB01582)

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Version 2.5
Creation Date 2007-08-29 14:54:18
Update Date 2009-02-19 16:03:48
Primary Accession Number DB01582
Secondary Accession Number Not Available
Name Sulfamethazine
Drug Type
  • Approved
  • Small Molecule
Description A sulfanilamide anti-infective agent. It has a spectrum of antimicrobial action similar to other sulfonamides. [PubChem]
Synonyms Not Available
Brand Names Not Available
Brand Mixtures Not Available
Chemical IUPAC Name 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide
Chemical Formula C12H14N4O2S
Chemical Structure Structure
CAS Registry Number 57-68-1
InChI Identifier InChI=1/C12H14N4O2S/c1-8-7-9(2)15-12(14-8)16-19(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3,(H,14,15,16)/f/h16H
InChI Key ASWVTGNCAZCNNR-WYUMXYHSCK
KEGG Drug Not Available
KEGG Compound Not Available
PubChem Compound 5327 Link Image
PubChem Substance 10452360 Link Image
ChEBI ID Not Available
PharmGKB ID PA451542 Link Image
HET ID Not Available
GenBank ID Not Available
Drug ID Number [DIN] Not Available
RxList Link Not Available
PDRhealth Link Not Available
Wikipedia Link Not Available
FDA Label Not Available
Material Safety Data Sheet (MSDS)
Synthesis Reference Not Available
Average Molecular Weight 278.3300
Monoisotopic Molecular Weight 278.0837
State Solid
Melting Point 198.5 oC
Experimental Water Solubility 1.5 mg/mL at 29 oC [MERCK INDEX (1983); at pH 7] Source: PhysProp
Predicted Water Solubility 2.30e-01 mg/mL Calculated using ALOGPS
Experimental LogP/Hydrophobicity 0.89 [BIOBYTE (1995)] Source: PhysProp
Predicted LogP 0.43 Calculated using ALOGPS
Experimental LogS Not Available
Predicted LogS -3.08 Calculated using ALOGPS
Experimental Caco2 Permeability Not Available
pKa/Isoelectric Point Not Available
Mass Spectrum Not Available
MOL File Show Link Image | Download Link Image
SDF File Show Link Image | Download Link Image
PDB File Show Link Image | Download Link Image
2D Structure
3D Structure
Experimental PDB ID Not Available
Isomeric SMILES CC1=CC(C)=NC(NS(=O)(=O)C2=CC=C(N)C=C2)=N1
Canonical SMILES CC1=CC(C)=NC(NS(=O)(=O)C2=CC=C(N)C=C2)=N1
Drug Category
  • Anti-Infective Agents
ATC Codes Not Available
AHFS Codes Not Available
Indication Not Available
Pharmacology Not Available
Mechanism of Action Not Available
Absorption Not Available
Toxicity Not Available
Protein Binding Not Available
Biotransformation Not Available
Half Life Not Available
Dosage Forms Not Available
Patient Information Not Available
Contraindications Not Available
Interactions Not Available
Drug Interactions Not Available
Food Interactions Not Available
Pathways Not Available
General References Not Available
Organisms Affected Not Available

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