Showing drug card for Sulfamethazine (DB01582)
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| Version | 2.5 |
| Creation Date | 2007-08-29 14:54:18 |
| Update Date | 2009-02-19 16:03:48 |
| Primary Accession Number | DB01582 |
| Secondary Accession Number | Not Available |
| Name | Sulfamethazine |
| Drug Type |
|
| Description | A sulfanilamide anti-infective agent. It has a spectrum of antimicrobial action similar to other sulfonamides. [PubChem] |
| Synonyms | Not Available |
| Brand Names | Not Available |
| Brand Mixtures | Not Available |
| Chemical IUPAC Name | 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide |
| Chemical Formula | C12H14N4O2S |
| Chemical Structure | |
| CAS Registry Number | 57-68-1 |
| InChI Identifier | InChI=1/C12H14N4O2S/c1-8-7-9(2)15-12(14-8)16-19(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3,(H,14,15,16)/f/h16H |
| InChI Key | ASWVTGNCAZCNNR-WYUMXYHSCK |
| KEGG Drug | Not Available |
| KEGG Compound | Not Available |
| PubChem Compound | 5327  |
| PubChem Substance | 10452360 |
| ChEBI ID | Not Available |
| PharmGKB ID | PA451542 |
| HET ID | Not Available |
| GenBank ID | Not Available |
| Drug ID Number [DIN] | Not Available |
| RxList Link | Not Available |
| PDRhealth Link | Not Available |
| Wikipedia Link | Not Available |
| FDA Label | Not Available |
| Material Safety Data Sheet (MSDS) | |
| Synthesis Reference | Not Available |
| Average Molecular Weight | 278.3300 |
| Monoisotopic Molecular Weight | 278.0837 |
| State | Solid |
| Melting Point | 198.5 oC |
| Experimental Water Solubility | 1.5 mg/mL at 29 oC [MERCK INDEX (1983); at pH 7] Source: PhysProp |
| Predicted Water Solubility | 2.30e-01 mg/mL Calculated using ALOGPS |
| Experimental LogP/Hydrophobicity | 0.89 [BIOBYTE (1995)] Source: PhysProp |
| Predicted LogP | 0.43 Calculated using ALOGPS |
| Experimental LogS | Not Available |
| Predicted LogS | -3.08 Calculated using ALOGPS |
| Experimental Caco2 Permeability | Not Available |
| pKa/Isoelectric Point | Not Available |
| Mass Spectrum | Not Available |
| MOL File | Show | Download |
| SDF File | Show | Download |
| PDB File | Show | Download |
| 2D Structure | |
| 3D Structure | |
| Experimental PDB ID | Not Available |
| Isomeric SMILES | CC1=CC(C)=NC(NS(=O)(=O)C2=CC=C(N)C=C2)=N1 |
| Canonical SMILES | CC1=CC(C)=NC(NS(=O)(=O)C2=CC=C(N)C=C2)=N1 |
| Drug Category |
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| ATC Codes | Not Available |
| AHFS Codes | Not Available |
| Indication | Not Available |
| Pharmacology | Not Available |
| Mechanism of Action | Not Available |
| Absorption | Not Available |
| Toxicity | Not Available |
| Protein Binding | Not Available |
| Biotransformation | Not Available |
| Half Life | Not Available |
| Dosage Forms | Not Available |
| Patient Information | Not Available |
| Contraindications | Not Available |
| Interactions | Not Available |
| Drug Interactions | Not Available |
| Food Interactions | Not Available |
| Pathways | Not Available |
| General References | Not Available |
| Organisms Affected | Not Available |