Showing BioInteractions for Vorinostat (DB02546)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
Interacting Group | Interacting Drugs | |
---|---|---|
Vorinostat is a Histone deacetylase 1 inhibitor | ||
1 | Histone deacetylase 1 inhibitors | Fingolimod, Romidepsin |
2 | Histone deacetylase 1 antagonists | Romidepsin |
3 | Histone deacetylase 1 cofactors | Zinc, Zinc chloride, Zinc sulfate, unspecified form |
Interacting Group | Interacting Drugs | |
---|---|---|
Vorinostat is a Histone deacetylase 2 inhibitor | ||
1 | Histone deacetylase 2 inhibitors | Atorvastatin, Fluvastatin, Pravastatin, Romidepsin, Simvastatin, Valproic acid |
2 | Histone deacetylase 2 activators | Aminophylline, Oxtriphylline, Theophylline |
3 | Histone deacetylase 2 antagonists | Romidepsin |
4 | Histone deacetylase 2 stimulators | Tixocortol |
Interacting Group | Interacting Drugs | |
---|---|---|
Vorinostat is a Histone deacetylase 3 inhibitor |
Interacting Group | Interacting Drugs | |
---|---|---|
Vorinostat is a Histone deacetylase 6 inhibitor | ||
1 | Histone deacetylase 6 inhibitors | Bufexamac, Romidepsin |