1. Triosephosphate isomerase, glycosomal

Pharmacological action: unknown

D-glyceraldehyde 3-phosphate = glycerone phosphate

Organism class: parasitic
UniProt ID: P52270
Protein Sequence: FASTA
Gene Sequence: FASTA

References:

1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. Pubmed
2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. Pubmed

2. Glycolipid transfer protein

Pharmacological action: unknown

Accelerates the intermembrane transfer of various glycolipids. Catalyzes the transfer of various glycosphingolipids and glyceroglycolipids between membranes but does not catalyze the transfer of phospholipids. It is possible that it is involved in the intracellular translocation of glucosylceramides

Organism class: human
UniProt ID: Q9NZD2
Gene: GLTP
Protein Sequence: FASTA
Gene Sequence: FASTA
SNPs: SNPJam Report

References:

1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. Pubmed
2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. Pubmed

3. Trypsin-1

Pharmacological action: unknown

Preferential cleavage:Arg-|-Xaa, Lys-|-Xaa

Organism class: human
UniProt ID: P07477
Gene: PRSS1
Protein Sequence: FASTA
Gene Sequence: FASTA
SNPs: SNPJam Report

References:

1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. Pubmed
2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. Pubmed
3. Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. Pubmed