Showing BioInteractions for Lactic acid (DB04398)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
Interacting Group | Interacting Drugs | |
---|---|---|
Lactic acid is a Monocarboxylate transporter 2 substrate | ||
1 | Monocarboxylate transporter 2 inhibitors | Acetoacetic acid, alpha-D-quinovopyranose, alpha-Ketoisovalerate, D-Lactic acid, gamma-Hydroxybutyric acid, Niflumic acid, Probenecid, Pyruvic acid, Quercetin |
2 | Monocarboxylate transporter 2 substrates | Pyruvic acid |
Interacting Group | Interacting Drugs | |
---|---|---|
Lactic acid is a Monocarboxylate transporter 2 inhibitor | ||
1 | Monocarboxylate transporter 2 inhibitors | Acetoacetic acid, alpha-D-quinovopyranose, alpha-Ketoisovalerate, D-Lactic acid, gamma-Hydroxybutyric acid, Niflumic acid, Probenecid, Pyruvic acid, Quercetin |
2 | Monocarboxylate transporter 2 substrates | Pyruvic acid |
Interacting Group | Interacting Drugs | |
---|---|---|
Lactic acid is a Monocarboxylate transporter 1 substrate | ||
1 | Monocarboxylate transporter 1 inhibitors | Acetoacetic acid, alpha-D-quinovopyranose, alpha-Ketoisovalerate, D-Lactic acid, gamma-Hydroxybutyric acid, Niflumic acid, Probenecid, Pyruvic acid, Quercetin |
2 | Monocarboxylate transporter 1 substrates | Acetic acid, Acetoacetic acid, Aminohippuric acid, Arbaclofen Placarbil, D-Lactic acid, Foscarnet, Glutamic acid, Methotrexate, Nateglinide, Niacin, Pravastatin, Pyruvic acid, Salicylic acid, Taurocholic acid, Valproic acid |
3 | Monocarboxylate transporter 1 antagonists | Mersalyl |
Interacting Group | Interacting Drugs | |
---|---|---|
Lactic acid is a Monocarboxylate transporter 1 inhibitor | ||
1 | Monocarboxylate transporter 1 inhibitors | Acetoacetic acid, alpha-D-quinovopyranose, alpha-Ketoisovalerate, D-Lactic acid, gamma-Hydroxybutyric acid, Niflumic acid, Probenecid, Pyruvic acid, Quercetin |
2 | Monocarboxylate transporter 1 substrates | Acetic acid, Acetoacetic acid, Aminohippuric acid, Arbaclofen Placarbil, D-Lactic acid, Foscarnet, Glutamic acid, Methotrexate, Nateglinide, Niacin, Pravastatin, Pyruvic acid, Salicylic acid, Taurocholic acid, Valproic acid |
3 | Monocarboxylate transporter 1 antagonists | Mersalyl |
Interacting Group | Interacting Drugs | |
---|---|---|
Lactic acid is a Monocarboxylate transporter 10 substrate | ||
1 | Monocarboxylate transporter 10 inhibitors | Alanine, Arginine, Asparagine, Aspartic acid, Cysteine, Cystine, D-Alanine, D-Leucine, D-Phenylalanine, D-Serine, D-Tryptophan, D-Tyrosine, Droxidopa, Glutamic acid, Glycine, Histidine, Isoleucine, L-Glutamine, Leucine, Levodopa, Liothyronine, Liotrix, Lysine, Methionine, Phenylalanine, Proline, Pyruvic acid, Serine, Threonine, Tryptophan, Tyrosine, Valine |
2 | Monocarboxylate transporter 10 substrates | 2-aminoisobutyric acid, beta-Alanine, D-Phenylalanine, Glutamic acid, Glycine, Histidine, Lysine, Pyruvic acid |
Interacting Group | Interacting Drugs | |
---|---|---|
Lactic acid is a Monocarboxylate transporter 10 inhibitor | ||
1 | Monocarboxylate transporter 10 inhibitors | Alanine, Arginine, Asparagine, Aspartic acid, Cysteine, Cystine, D-Alanine, D-Leucine, D-Phenylalanine, D-Serine, D-Tryptophan, D-Tyrosine, Droxidopa, Glutamic acid, Glycine, Histidine, Isoleucine, L-Glutamine, Leucine, Levodopa, Liothyronine, Liotrix, Lysine, Methionine, Phenylalanine, Proline, Pyruvic acid, Serine, Threonine, Tryptophan, Tyrosine, Valine |
2 | Monocarboxylate transporter 10 substrates | 2-aminoisobutyric acid, beta-Alanine, D-Phenylalanine, Glutamic acid, Glycine, Histidine, Lysine, Pyruvic acid |
Interacting Group | Interacting Drugs | |
---|---|---|
Lactic acid is a Solute carrier organic anion transporter family member 2A1 inhibitor | ||
1 | Solute carrier organic anion transporter family member 2A1 inducers | Phenobarbital |
2 | Solute carrier organic anion transporter family member 2A1 inhibitors | beta-D-fructofuranose 1,6-bisphosphate, D-glyceraldehyde 3-phosphate, Furosemide, Glucose-6-Phosphate, Phosphoenolpyruvate, Pyruvic acid, Rifamycin |
3 | Solute carrier organic anion transporter family member 2A1 substrates | Alprostadil, Arachidonic Acid, Dinoprostone, Iloprost, Latanoprost |
Interacting Group | Interacting Drugs | |
---|---|---|
Lactic acid is a Monocarboxylate transporter 4 substrate | ||
1 | Monocarboxylate transporter 4 substrates | Acetoacetic acid, alpha-Ketoisovalerate, D-Lactic acid, Formic acid, gamma-Hydroxybutyric acid, Glyoxylic acid, Oxamic Acid, Phenylpyruvic acid, Pyruvic acid |