Showing BioInteractions for Suramin (DB04786)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Suramin is a NAD-dependent protein deacylase sirtuin-5, mitochondrial inhibitor | ||
| 1 | NAD-dependent protein deacylase sirtuin-5, mitochondrial inhibitors | Cambinol |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Suramin is a Phospholipase A2, membrane associated inhibitor | ||
| 1 | Phospholipase A2, membrane associated inhibitors | Diclofenac, Ginkgo biloba, Indomethacin |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Suramin is a Prothrombin inhibitor | ||
| 1 | Prothrombin inhibitors | Antithrombin Alfa, Argatroban, Betrixaban, Bivalirudin, Conestat alfa, Dabigatran etexilate, Enoxaparin, Gabexate, Human C1-esterase inhibitor, Lepirudin, Nafamostat, Thrombomodulin Alfa, Ximelagatran |
| 2 | Prothrombin activators | Antihemophilic factor, human recombinant, Lonoctocog alfa, Menadione, Moroctocog alfa |
| 3 | Prothrombin agonists | Anti-inhibitor coagulant complex, Kappadione |
| 4 | Prothrombin substrates | Anti-inhibitor coagulant complex |
| 5 | Prothrombin binders | Turoctocog alfa, Turoctocog alfa pegol |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Suramin is a P2Y purinoceptor 2 antagonist | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Suramin is a Follicle-stimulating hormone receptor antagonist | ||
| 1 | Follicle-stimulating hormone receptor binders | Choriogonadotropin alfa, Menotropins |
| 2 | Follicle-stimulating hormone receptor agonists | Corifollitropin alfa, Follitropin, Urofollitropin |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Suramin is a Ryanodine receptor 1 agonist | ||
| 1 | Ryanodine receptor 1 antagonists | Dantrolene |
| 2 | Ryanodine receptor 1 modulators | Tetracaine |
| 3 | Ryanodine receptor 1 substrates | Calcium citrate, Calcium Phosphate |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Suramin is a Arylsulfatase A inhibitor | ||
| 1 | Arylsulfatase A substrates | Micafungin |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Suramin is a Cytosolic phospholipase A2 inhibitor | ||
| 1 | Cytosolic phospholipase A2 inhibitors | Carbenicillin, Epirubicin, Fluticasone, Fluticasone propionate, Lancovutide, Orlistat, Procaine, Quinacrine |
| 2 | Cytosolic phospholipase A2 inducers | Aldesleukin, Carbamoylcholine, Streptokinase |
| 3 | Cytosolic phospholipase A2 substrates | Urethane |