Showing BioInteractions for Cinitapride (DB08810)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.

Target Mediated Interactions 3

	Interacting Group	Interacting Drugs
	Cinitapride is a 5-hydroxytryptamine receptor 1A agonist
1	5-hydroxytryptamine receptor 1A partial agonists	Aripiprazole, Aripiprazole lauroxil, Brexpiprazole, Buspirone, Cariprazine, Perospirone, Quetiapine, Trazodone, Yohimbine
2	5-hydroxytryptamine receptor 1A agonists	5-methoxy-N,N-dimethyltryptamine, Apomorphine, Brexpiprazole, Bromocriptine, Cabergoline, Cannabidiol, Cariprazine, Eletriptan, Ergotamine, Fenfluramine, Flibanserin, Lisuride, Lofexidine, Methysergide, Naluzotan, Naratriptan, Pergolide, Pramipexole, Rotigotine, SEP-363856, Sumatriptan, Tetrahydrocannabivarin, Vilazodone, Vortioxetine, Ziprasidone, Zolmitriptan
3	5-hydroxytryptamine receptor 1A antagonists	Acepromazine, Alprenolol, Alverine, Amoxapine, Asenapine, Chlorpromazine, Clozapine, Dosulepin, Doxepin, Iloperidone, Lurasidone, Molindone, Nefazodone, Nortriptyline, Paliperidone, Penbutolol, Pindolol, Pipotiazine, Pirlindole, Pizotifen, Quetiapine, Risperidone, Thioproperazine, Trazodone, Trimipramine
4	5-hydroxytryptamine receptor 1A inhibitors	Amitriptyline, Escitalopram, Tianeptine
5	5-hydroxytryptamine receptor 1A inducers	Amitriptyline
6	5-hydroxytryptamine receptor 1A binders	Desipramine, Dopamine, Loxapine
7	5-hydroxytryptamine receptor 1A activators	Imipramine
8	5-hydroxytryptamine receptor 1A blockers	Mianserin

	Interacting Group	Interacting Drugs
	Cinitapride is a 5-hydroxytryptamine receptor 4 agonist
1	5-hydroxytryptamine receptor 4 agonists	Cisapride, Metoclopramide, Naronapride, Ondansetron, Prucalopride
2	5-hydroxytryptamine receptor 4 antagonists	Tegaserod
3	5-hydroxytryptamine receptor 4 partial agonists	Tegaserod

	Interacting Group	Interacting Drugs
	Cinitapride is a 5-hydroxytryptamine receptor 2A antagonist
1	5-hydroxytryptamine receptor 2A antagonists	Acepromazine, Amisulpride, Amitriptyline, Amoxapine, Amperozide, Aripiprazole, Aripiprazole lauroxil, Asenapine, Blonanserin, Brexpiprazole, Butriptyline, Cariprazine, Chlorpromazine, Chlorprothixene, Clomipramine, Clozapine, Cyclobenzaprine, Cyproheptadine, Deramciclane, Desipramine, Dosulepin, Doxepin, Epinastine, Etoperidone, Flibanserin, Flupentixol, Fluspirilene, Iloperidone, Imipramine, Lorpiprazole, Loxapine, Lumateperone, Lurasidone, Mesoridazine, Methotrimeprazine, Methysergide, Mianserin, Minaprine, Mirtazapine, Molindone, Nefazodone, Nortriptyline, Olanzapine, Paliperidone, Pipotiazine, Pizotifen, Promazine, Propiomazine, Quetiapine, Risperidone, Sertindole, Tegaserod, Thioproperazine, Thioridazine, Thiothixene, Trazodone, Yohimbine, Ziprasidone, Zotepine, Zuclopenthixol
2	5-hydroxytryptamine receptor 2A partial agonists	4-Bromo-2,5-dimethoxyphenethylamine, Aripiprazole
3	5-hydroxytryptamine receptor 2A agonists	2,5-Dimethoxy-4-ethylthioamphetamine, 5-methoxy-N,N-dimethyltryptamine, Apomorphine, Bromocriptine, Cabergoline, Cannabidiol, Cisapride, Ergotamine, Fenfluramine, Lisuride, Midomafetamine, MMDA, N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine, Paroxetine, Pergolide, Pipamperone, Trimipramine, Zolmitriptan
4	5-hydroxytryptamine receptor 2A inducers	Donepezil
5	5-hydroxytryptamine receptor 2A inverse agonists	Ketanserin, Perospirone, Pimavanserin, Ritanserin, Sarpogrelate
6	5-hydroxytryptamine receptor 2A binders	Maprotiline
7	5-hydroxytryptamine receptor 2A inhibitors	Escitalopram, Lamotrigine