Showing BioInteractions for Captodiame (DB09014)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.

Target Mediated Interactions 3

	Interacting Group	Interacting Drugs
	Captodiame is a 5-hydroxytryptamine receptor 2C antagonist
1	5-hydroxytryptamine receptor 2C agonists	2,5-Dimethoxy-4-ethylthioamphetamine, Apomorphine, Bromocriptine, Cabergoline, Dexfenfluramine, Ergotamine, Etoperidone, Fenfluramine, Lisuride, Lofexidine, m-Chlorophenylpiperazine, Midomafetamine, Pergolide, Trazodone
2	5-hydroxytryptamine receptor 2C antagonists	Agomelatine, Amitriptyline, Amoxapine, Aripiprazole, Asenapine, Clomipramine, Clozapine, Cyclobenzaprine, Cyproheptadine, Doxepin, Fluoxetine, Imipramine, Lorpiprazole, Loxapine, Methotrimeprazine, Methysergide, Mianserin, Minaprine, Mirtazapine, Nefazodone, Nortriptyline, Olanzapine, Paliperidone, Pizotifen, Promazine, Propiomazine, Risperidone, Sertindole, Tegaserod, Tramadol, Trimipramine, Yohimbine, Ziprasidone
3	5-hydroxytryptamine receptor 2C ligands	Quetiapine
4	5-hydroxytryptamine receptor 2C inverse agonists	Deramciclane
5	5-hydroxytryptamine receptor 2C partial agonists	4-Bromo-2,5-dimethoxyphenethylamine, Aripiprazole
6	5-hydroxytryptamine receptor 2C binders	Chlorpromazine, Desipramine, Imipramine, Maprotiline
7	5-hydroxytryptamine receptor 2C inhibitors	Escitalopram

	Interacting Group	Interacting Drugs
	Captodiame is a Sigma non-opioid intracellular receptor 1 agonist
1	Sigma non-opioid intracellular receptor 1 agonists	Amitriptyline, Cocaine, Dextromethorphan, Pentazocine, Pentoxyverine, Prasterone
2	Sigma non-opioid intracellular receptor 1 antagonists	Fenfluramine, Remoxipride
3	Sigma non-opioid intracellular receptor 1 ligands	Hydrocodone

	Interacting Group	Interacting Drugs
	Captodiame is a Dopamine D3 receptor agonist
1	Dopamine D3 receptor antagonists	Amisulpride, Amoxapine, Aripiprazole, AS-8112, Asenapine, Blonanserin, Buspirone, Chlorprothixene, Clozapine, Domperidone, Iloperidone, Methotrimeprazine, Olanzapine, Paliperidone, Pimozide, Remoxipride, Sulpiride, Yohimbine, Ziprasidone
2	Dopamine D3 receptor agonists	Apomorphine, Bromocriptine, Cabergoline, Cariprazine, Dopamine, Levodopa, Lisuride, Pergolide, Pramipexole, Ropinirole, Rotigotine, Tianeptine
3	Dopamine D3 receptor partial agonists	Aripiprazole, Cariprazine, Dihydro-alpha-ergocryptine
4	Dopamine D3 receptor inverse agonists	Haloperidol
5	Dopamine D3 receptor ligands	Quetiapine, Sarizotan
6	Dopamine D3 receptor inhibitors	Chlorpromazine
7	Dopamine D3 receptor binders	Loxapine, Mianserin
8	Dopamine D3 receptor blockers	Tiapride