This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Glyceryl monostearate
- DrugBank Accession Number
- DB11250
- Background
Glycerol monostearate, commonly known as GMS, is the glycerol ester of stearic acid . It is commonly used as an emulsifier in foods.
- Type
- Small Molecule
- Groups
- Experimental
- Structure
Structure for Glyceryl monostearate (DB11250)
- Weight
- Average: 358.5558
Monoisotopic: 358.308309832 - Chemical Formula
- C21H42O4
- Synonyms
- Geleol mono and diglycerides
- Glycerin monostearate
- Glycerol monostearate
- Glyceroli monostearas
- Glyceryl monooctadecanoate
- Glyceryl monopalmitostearate
- Glyceryl stearate
- Monoglyceryl stearate
- Monostearate (glyceride)
- Monostearin
- Stearic acid, monoester with glycerol
- Stearoylglycerol
Pharmacology
- Indication
Not Available
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Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Banacos Cica Mask Glyceryl monostearate (0.416 g/100g) + Allantoin (0.01 g/100g) + Ethanol (0.01 mL/100g) Patch Topical Cleoslab Co.,Ltd 2020-07-16 Not applicable US 
Cho-A Care Lot 1% Glyceryl monostearate (10 mg/50g) + Hydrocortisone (10 mg/50g) Lotion Topical Cho-A Pharm.Co.,Ltd. 2019-10-25 Not applicable US Fresh Med Solution Glyceryl monostearate (0.4 mL/40mL) + Ethanol (1.6 mL/40mL) Liquid Topical ATOMY CO LTD 2011-06-24 2011-06-24 US Fresh Med Solution Glyceryl monostearate (0.4 g/40mL) + Ethanol (1.6 g/40mL) + Glycerin (1.744 g/40mL) Liquid Topical Atomy Co., Ltd. 2011-07-18 2017-12-01 US Fresh Med Solution Glyceryl monostearate (0.4 mL/40mL) + Ethanol (1.6 mL/40mL) + Glycerin (1.744 mL/40mL) Liquid Topical ATOMY CO LTD 2011-07-01 2011-07-01 US - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Fresh Med Solution Glyceryl monostearate (0.4 mL/40mL) + Ethanol (1.6 mL/40mL) Liquid Topical ATOMY CO LTD 2011-06-24 2011-06-24 US Mycellcare All in One Serum Glyceryl monostearate (0.728 g/100mL) + Allantoin (0.145 g/100mL) + Glycerin (4.16 g/100mL) + Nicotinamide (2.8 g/100mL) Liquid Topical PHARMACAL-INTERNATIONAL. CO., LTD 2017-08-16 Not applicable US
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 258491E1RZ
- CAS number
- 31566-31-1
- InChI Key
- VBICKXHEKHSIBG-UHFFFAOYSA-N
- InChI
- InChI=1S/C21H42O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h20,22-23H,2-19H2,1H3
- IUPAC Name
- 2,3-dihydroxypropyl octadecanoate
- SMILES
- CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO
References
- General References
- Not Available
- External Links
- Human Metabolome Database
- HMDB0031075
- ChemSpider
- 23095
- 1311155
- ChEBI
- 75555
- ChEMBL
- CHEMBL255696
- Wikipedia
- Glycerol_monostearate
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Patch Topical Lotion Topical Liquid Topical - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.00108 mg/mL ALOGPS logP 6.73 ALOGPS logP 5.97 Chemaxon logS -5.5 ALOGPS pKa (Strongest Acidic) 13.62 Chemaxon pKa (Strongest Basic) -3 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 66.76 Å2 Chemaxon Rotatable Bond Count 20 Chemaxon Refractivity 103.31 m3·mol-1 Chemaxon Polarizability 46.63 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 0 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 231.3163824 predictedDarkChem Lite v0.1.0 [M-H]- 188.87633 predictedDeepCCS 1.0 (2019) [M+H]+ 232.2132824 predictedDarkChem Lite v0.1.0 [M+H]+ 191.42664 predictedDeepCCS 1.0 (2019) [M+Na]+ 229.4525824 predictedDarkChem Lite v0.1.0 [M+Na]+ 198.49011 predictedDeepCCS 1.0 (2019)
Drug created at December 03, 2015 16:51 / Updated at June 12, 2020 16:53