NAV

Perflenapent

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Perflenapent
DrugBank Accession Number
DB11625
Background

Dodecafluoropentane is also known as perfluoropentane or perflenapent.

Type
Small Molecule
Groups
Investigational, Withdrawn
Structure
3D
Similar Structures
Weight
Average: 288.036
Monoisotopic: 287.980837956
Chemical Formula
C5F12
Synonyms
  • Dodecafluoropentane
  • dodecafluoropentane emulsion (DDFPe)
  • Perfluoropentane
External IDs
  • FC 4112
  • FC 87
  • NVX-108
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Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

ATC Codes
V08DA03 — Perflenapent
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as organofluorides. These are compounds containing a chemical bond between a carbon atom and a fluorine atom.
Kingdom
Organic compounds
Super Class
Organohalogen compounds
Class
Organofluorides
Sub Class
Not Available
Direct Parent
Organofluorides
Alternative Parents
Hydrocarbon derivatives / Alkyl fluorides
Substituents
Aliphatic acyclic compound / Alkyl fluoride / Alkyl halide / Hydrocarbon derivative / Organofluoride
Molecular Framework
Aliphatic acyclic compounds
External Descriptors
fluoroalkane (CHEBI:39428)
Affected organisms
Not Available

Chemical Identifiers

UNII
483AU1Y5CZ
CAS number
678-26-2
InChI Key
NJCBUSHGCBERSK-UHFFFAOYSA-N
InChI
InChI=1S/C5F12/c6-1(7,2(8,9)4(12,13)14)3(10,11)5(15,16)17
IUPAC Name
dodecafluoropentane
SMILES
FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

References

General References
Not Available
Human Metabolome Database
HMDB0251565
ChemSpider
12154
RxNav
2474632
ChEBI
39428
ChEMBL
CHEMBL1899801
ZINC
ZINC000008214647
Wikipedia
Perfluoropentane

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
2RecruitingTreatmentGlioblastoma Multiforme (GBM)1
2, 3Not Yet RecruitingTreatmentIschemic Stroke1
1CompletedTreatmentGlioblastoma Multiforme (GBM)1
1CompletedTreatmentIschemic Stroke1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.0383 mg/mLALOGPS
logP3.28ALOGPS
logP4.18Chemaxon
logS-3.9ALOGPS
Physiological Charge0Chemaxon
Hydrogen Acceptor Count0Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area0 Å2Chemaxon
Rotatable Bond Count4Chemaxon
Refractivity26.87 m3·mol-1Chemaxon
Polarizability11.38 Å3Chemaxon
Number of Rings0Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-000i-0090000000-957693869a85b6fdab02
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-000i-0090000000-51a985a35de041a50334
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-00kr-0090000000-31a61306a95fb9215160
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
[M-H]-149.40767
predicted
DeepCCS 1.0 (2019)
[M+H]+151.80324
predicted
DeepCCS 1.0 (2019)
[M+Na]+157.92613
predicted
DeepCCS 1.0 (2019)

Drug created at October 17, 2016 21:25 / Updated at July 18, 2023 22:56