NAV

Metenolone

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Metenolone is an anabolic steroid indicated in the treatment and prevention of muscle wasting due to diseases, drug treatments, or other catabolic processes.

Generic Name
Metenolone
DrugBank Accession Number
DB13710
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
3D
Similar Structures
Weight
Average: 302.451
Monoisotopic: 302.224580204
Chemical Formula
C20H30O2
Synonyms
  • Metenolona
  • Metenolone
  • Methenolone
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Pharmacology

Indication

Not Available

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Associated Conditions
Indication TypeIndicationCombined Product DetailsApproval LevelAge GroupPatient CharacteristicsDose Form
Management ofCatabolic state•••••••••••••••••••••• ••••••••
Associated Therapies
Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
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Beclomethasone dipropionateThe risk or severity of edema formation can be increased when Metenolone is combined with Beclomethasone dipropionate.
BetamethasoneThe risk or severity of edema formation can be increased when Metenolone is combined with Betamethasone.
Betamethasone phosphateThe risk or severity of edema formation can be increased when Metenolone is combined with Betamethasone phosphate.
BudesonideThe risk or severity of edema formation can be increased when Metenolone is combined with Budesonide.
CiclesonideThe risk or severity of edema formation can be increased when Metenolone is combined with Ciclesonide.
Food Interactions
Not Available

Products

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Categories

ATC Codes
A14AA04 — Metenolone
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as androgens and derivatives. These are 3-hydroxylated C19 steroid hormones. They are known to favor the development of masculine characteristics. They also show profound effects on scalp and body hair in humans.
Kingdom
Organic compounds
Super Class
Lipids and lipid-like molecules
Class
Steroids and steroid derivatives
Sub Class
Androstane steroids
Direct Parent
Androgens and derivatives
Alternative Parents
3-oxo-5-alpha-steroids / 3-oxo delta-1-steroids / 17-hydroxysteroids / Delta-1-steroids / Cyclohexenones / Secondary alcohols / Cyclic alcohols and derivatives / Organic oxides / Hydrocarbon derivatives
Substituents
17-hydroxysteroid / 3-oxo-5-alpha-steroid / 3-oxo-delta-1-steroid / 3-oxosteroid / Alcohol / Aliphatic homopolycyclic compound / Androgen-skeleton / Carbonyl group / Cyclic alcohol / Cyclic ketone
Molecular Framework
Aliphatic homopolycyclic compounds
External Descriptors
C19 steroids (androgens) and derivatives (LMST02020028)
Affected organisms
Not Available

Chemical Identifiers

UNII
9062ZT8Q5C
CAS number
153-00-4
InChI Key
ANJQEDFWRSLVBR-VHUDCFPWSA-N
InChI
InChI=1S/C20H30O2/c1-12-10-14(21)11-13-4-5-15-16-6-7-18(22)19(16,2)9-8-17(15)20(12,13)3/h10,13,15-18,22H,4-9,11H2,1-3H3/t13-,15-,16-,17-,18-,19-,20-/m0/s1
IUPAC Name
(1S,3aS,3bR,5aS,9aS,9bS,11aS)-1-hydroxy-9,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,5aH,6H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
SMILES
[H][C@]1(O)CC[C@@]2([H])[C@]3([H])CC[C@@]4([H])CC(=O)C=C(C)[C@]4(C)[C@@]3([H])CC[C@]12C

References

General References
  1. TITCK Product Information: Rimobolan (methenolone enanthate) solution for intramuscular injection [Link]
Human Metabolome Database
HMDB0041928
ChemSpider
2301378
RxNav
6833
ChEBI
135283
ZINC
ZINC000005497532
Wikipedia
Metenolone

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
SolutionIntramuscular100 mg/1ml
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.022 mg/mLALOGPS
logP3.45ALOGPS
logP3.65Chemaxon
logS-4.1ALOGPS
pKa (Strongest Acidic)19.38Chemaxon
pKa (Strongest Basic)-0.88Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count2Chemaxon
Hydrogen Donor Count1Chemaxon
Polar Surface Area37.3 Å2Chemaxon
Rotatable Bond Count0Chemaxon
Refractivity88.98 m3·mol-1Chemaxon
Polarizability35.88 Å3Chemaxon
Number of Rings4Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted GC-MS Spectrum - GC-MSPredicted GC-MSsplash10-05g0-0290000000-541020c4a6431e6bc339
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-0udi-0069000000-2cdefc529141726addfe
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-0udi-0009000000-6910ef310c48d110a3e1
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-001r-1691000000-eebd3003cfdacf9a07ee
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-0udi-0009000000-079cc44920a32d9fa75f
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-0f89-0094000000-fae6e4307f4e353ca337
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-0a4s-0910000000-b7fd76ae8d7bad0a26d9
Predicted 1H NMR Spectrum1D NMRNot Applicable
Predicted 13C NMR Spectrum1D NMRNot Applicable
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
[M-H]-180.0524164
predicted
DarkChem Lite v0.1.0
[M-H]-179.8735164
predicted
DarkChem Lite v0.1.0
[M-H]-180.0345164
predicted
DarkChem Lite v0.1.0
[M-H]-166.12024
predicted
DeepCCS 1.0 (2019)
[M+H]+180.6803164
predicted
DarkChem Lite v0.1.0
[M+H]+180.5445164
predicted
DarkChem Lite v0.1.0
[M+H]+180.8578164
predicted
DarkChem Lite v0.1.0
[M+H]+168.01566
predicted
DeepCCS 1.0 (2019)
[M+Na]+180.3863164
predicted
DarkChem Lite v0.1.0
[M+Na]+180.1315164
predicted
DarkChem Lite v0.1.0
[M+Na]+180.0687164
predicted
DarkChem Lite v0.1.0
[M+Na]+173.86295
predicted
DeepCCS 1.0 (2019)

Drug created at June 23, 2017 20:47 / Updated at May 29, 2021 18:12