Carbaryl
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Summary
Carbaryl is a medication used in shampoo to remove lice.
- Generic Name
- Carbaryl
- DrugBank Accession Number
- DB15930
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
- Weight
- Average: 201.225
Monoisotopic: 201.078978598 - Chemical Formula
- C12H11NO2
- Synonyms
- Carbaril
- Carbarilo
- Carbarilum
- Karbaryl
- External IDs
- 200-555-0
- ENT-23969
- NSC-27311
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Treatment of Head lice infestation •••••••••••• ••••••• - Contraindications & Blackbox Warnings
- Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API
- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareDipyridamole The therapeutic efficacy of Carbaryl can be decreased when used in combination with Dipyridamole. - Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- R890C8J3N1
- CAS number
- 63-25-2
- InChI Key
- CVXBEEMKQHEXEN-UHFFFAOYSA-N
- InChI
- InChI=1S/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)
- IUPAC Name
- naphthalen-1-yl N-methylcarbamate
- SMILES
- CNC(=O)OC1=C2C=CC=CC2=CC=C1
References
- General References
- FDA Thailand: HAFIF (carbaryl) shampoo [Link]
- External Links
- KEGG Compound
- C07491
- ChemSpider
- 5899
- BindingDB
- 50128572
- 9724
- ChEBI
- 3390
- ChEMBL
- CHEMBL46917
- ZINC
- ZINC000000001090
- Wikipedia
- Carbaryl
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Lotion Topical 0.65 g Solution Topical 0.65 g Shampoo Topical 0.6 %w/v - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.0914 mg/mL ALOGPS logP 2.45 ALOGPS logP 2.46 Chemaxon logS -3.3 ALOGPS pKa (Strongest Acidic) 14.77 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 1 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 38.33 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 57.21 m3·mol-1 Chemaxon Polarizability 21.12 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS splash10-0a4j-9400000000-66b9b0cf2d3fe48c28ce Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS splash10-0a4i-9400000000-2967e0467eeb90521a60 Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS splash10-0002-2900000000-17f03baccea3f7d1b5d7 Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS splash10-0006-1900000000-d2b9b21ed105ecb8b9e2 Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS splash10-0006-2900000000-05e17a30bbc8ec903f9a Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS splash10-1003-9600000000-23a06db04f74922aa601 Predicted 1H NMR Spectrum 1D NMR Not Applicable Predicted 13C NMR Spectrum 1D NMR Not Applicable - Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 150.3951121 predictedDarkChem Lite v0.1.0 [M-H]- 150.7878121 predictedDarkChem Lite v0.1.0 [M-H]- 138.35101 predictedDeepCCS 1.0 (2019) [M+H]+ 151.2608121 predictedDarkChem Lite v0.1.0 [M+H]+ 151.2845121 predictedDarkChem Lite v0.1.0 [M+H]+ 140.74658 predictedDeepCCS 1.0 (2019) [M+Na]+ 150.4973121 predictedDarkChem Lite v0.1.0 [M+Na]+ 147.63121 predictedDeepCCS 1.0 (2019)
Drug created at November 24, 2020 16:28 / Updated at May 07, 2021 21:08