Alfentanil hydrochlorideProduct ingredient for Alfentanil
- Name
- Alfentanil hydrochloride
- Drug Entry
- Alfentanil
A short-acting opioid anesthetic and analgesic derivative of fentanyl. It produces an early peak analgesic effect and fast recovery of consciousness. Alfentanil is effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and as an analgesic for critically ill patients.
- Accession Number
- DBSALT001202
- Structure
- Synonyms
- Alfentanil HCl
- UNII
- 11S92G0TIW
- CAS Number
- 70879-28-6
- Weight
- Average: 471.0
Monoisotopic: 470.2408313 - Chemical Formula
- C21H35ClN6O4
- InChI Key
- YYESXRRYBUERKF-UHFFFAOYSA-N
- InChI
- InChI=1S/C21H32N6O3.ClH.H2O/c1-4-19(28)27(18-9-7-6-8-10-18)21(17-30-3)11-13-24(14-12-21)15-16-26-20(29)25(5-2)22-23-26;;/h6-10H,4-5,11-17H2,1-3H3;1H;1H2
- IUPAC Name
- N-{1-[2-(4-ethyl-5-oxo-4,5-dihydro-1H-1,2,3,4-tetrazol-1-yl)ethyl]-4-(methoxymethyl)piperidin-4-yl}-N-phenylpropanamide hydrate hydrochloride
- SMILES
- O.Cl.CCN1N=NN(CCN2CCC(COC)(CC2)N(C(=O)CC)C2=CC=CC=C2)C1=O
- External Links
- ChemSpider
- 58296
- Wikipedia
- Alfentanil
- Predicted Properties
Property Value Source Water Solubility 0.252 mg/mL ALOGPS logP 2.2 ALOGPS logP 2.81 Chemaxon logS -3.2 ALOGPS pKa (Strongest Basic) 7.5 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 81.05 Å2 Chemaxon Rotatable Bond Count 9 Chemaxon Refractivity 118.59 m3·mol-1 Chemaxon Polarizability 44.72 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon