Benzocaine hydrochlorideProduct ingredient for Benzocaine

Name
Benzocaine hydrochloride
Drug Entry
Benzocaine

Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.4 It is commonly used for local anesthesia in many over the counter products.13,14,15 Benzocaine was first used for local anesthesia in dentistry.10

Accession Number
DBSALT001560
Structure
Synonyms
Benzocaine HCl
UNII
OG625Z9LEO
CAS Number
23239-88-5
Weight
Average: 201.65
Monoisotopic: 201.0556563
Chemical Formula
C9H12ClNO2
InChI Key
JAADDQHUJDUAKW-UHFFFAOYSA-N
InChI
InChI=1S/C9H11NO2.ClH/c1-2-12-9(11)7-3-5-8(10)6-4-7;/h3-6H,2,10H2,1H3;1H
IUPAC Name
ethyl 4-aminobenzoate hydrochloride
SMILES
Cl.CCOC(=O)C1=CC=C(N)C=C1
ChemSpider
8389954
Predicted Properties
PropertyValueSource
Water Solubility2.85 mg/mLALOGPS
logP2.2ALOGPS
logP1.5Chemaxon
logS-1.8ALOGPS
pKa (Strongest Basic)2.78Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count2Chemaxon
Hydrogen Donor Count1Chemaxon
Polar Surface Area52.32 Å2Chemaxon
Rotatable Bond Count3Chemaxon
Refractivity47.53 m3·mol-1Chemaxon
Polarizability17.46 Å3Chemaxon
Number of Rings1Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon