Benzocaine hydrochlorideProduct ingredient for Benzocaine
- Name
- Benzocaine hydrochloride
- Drug Entry
- Benzocaine
Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.4 It is commonly used for local anesthesia in many over the counter products.13,14,15 Benzocaine was first used for local anesthesia in dentistry.10
- Accession Number
- DBSALT001560
- Structure
- Synonyms
- Benzocaine HCl
- UNII
- OG625Z9LEO
- CAS Number
- 23239-88-5
- Weight
- Average: 201.65
Monoisotopic: 201.0556563 - Chemical Formula
- C9H12ClNO2
- InChI Key
- JAADDQHUJDUAKW-UHFFFAOYSA-N
- InChI
- InChI=1S/C9H11NO2.ClH/c1-2-12-9(11)7-3-5-8(10)6-4-7;/h3-6H,2,10H2,1H3;1H
- IUPAC Name
- ethyl 4-aminobenzoate hydrochloride
- SMILES
- Cl.CCOC(=O)C1=CC=C(N)C=C1
- External Links
- ChemSpider
- 8389954
- Predicted Properties
Property Value Source Water Solubility 2.85 mg/mL ALOGPS logP 2.2 ALOGPS logP 1.5 Chemaxon logS -1.8 ALOGPS pKa (Strongest Basic) 2.78 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 52.32 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 47.53 m3·mol-1 Chemaxon Polarizability 17.46 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon