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Identification
NamePyridoxine
Accession NumberDB00165  (APRD00204, NUTR00002)
TypeSmall Molecule
GroupsApproved, Nutraceutical
Description

Pyridoxine is the 4-methanol form of vitamin B6 and is converted to pyridoxal 5-phosphate in the body. Pyridoxal 5-phosphate is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. Although pyridoxine and vitamin B6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading. [PubChem]

Structure
Thumb
Synonyms
2-Methyl-3-hydroxy-4,5-dihydroxymethylpyridine
3-hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridine
3-Hydroxy-4,5-dimethylol-alpha-picoline
5-Hydroxy-6-methyl-3,4-pyridinedimethanol
Pyridoxine
Pyridoxol
Vitamin B6
External Identifiers Not Available
Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
B6 400mg Ctr Tabtablet (extended-release)400 mgBioenergy Inc.1979-12-311998-06-03Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Cataplex F Tab 2mgtablet2 mgoralStandard Process Inc.Not applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pyridoxine HCl Inj 100mg/mlliquid100 mgintramuscular; intravenousKripps Pharmacy Ltd.1979-12-31Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pyridoxine HCl Tab 100mgtablet100 mgEverest Pharmaceuticals Ltd.1980-12-311999-07-14Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pyridoxine Hydrochloride Injection 100mg/mlsolution100 mgintramuscular; intravenousHospira Healthcare Corporation1981-12-31Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pyridoxine Hydrochloride Injection USP 100 mg/mlsolution100 mgintramuscular; intravenousAlveda Pharmaceuticals IncNot applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pyridoxine Hydrochloride Injection, USPsolution100 mgintramuscular; intravenousMylan Pharmaceuticals Ulc2002-06-01Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vit B6 Ctr Srt 100mgtablet (extended-release)100 mgBioenergy Inc.1981-12-311998-06-03Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B6 250 Mg Capsulescapsule250 mgoralSelf Health Resource CentreNot applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B6 Tablettablet100 mgoralLeiner Health Products Inc.Not applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Generic Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Pyridoxine Hydrochlorideinjection, solution100 mg/mLintramuscular; intravenousFresenius Kabi USA, LLC1972-08-14Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Acti-pyridoxine/pyridoxal 5-phosph 100 Tabtablet100 mgoralActi Form Ltd.1991-12-312005-03-21Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Acti-pyridoxine/pyridoxal 5-phosph 250 Tabtablet250 mgoralActi Form Ltd.1991-12-312005-03-21Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
B-6 500mg Continuous Releasedtablet (extended-release)500 mgoralGahler Enterprises Ltd.1981-12-312007-08-07Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
B-6 Caps 250mgcapsule250 mgoralTwin Laboratories Inc.1995-12-311999-11-10Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
B6 100mg Pyridoxine HCltablet100 mgoralWn Pharmaceuticals Ltd.2001-10-012009-09-28Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
B6 25 Tab 25mgtablet25 mgoralLe Naturiste J.M.B. Inc.1990-12-311997-07-23Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
B6 250 Caplet 250mgtablet250 mgoralHealth Wise Nutrition Inc.1996-11-131997-08-07Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
B6 Cap 100mgcapsule100 mgoralGahler Enterprises Ltd.1989-12-312008-07-17Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
B6 Pyridoxine HCl Tab 50mgtablet50 mgoralGahler Enterprises Ltd.1984-12-312008-07-17Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
B6 Tab 100mgtablet100 mgoralAlbi Naturals1979-12-312008-07-17Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
B6 Tablets 100mgtablet100 mgoralGahler Enterprises Ltd.1988-12-312008-07-17Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Formula A.L.- Tab 17mgtablet17 mgoralAbundance Marketing Ltd.1996-11-051999-08-06Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Formule No 202 Profil Tab 8.45gmtablet8.45 mgoralPharmalab Inc.1987-12-312001-07-30Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Hi Potency Klb6 Tab 17mgtablet17 mgoralSwiss Herbal Remedies Ltd.1981-12-312003-09-10Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Klb 6 Tabtablet6 mgoralHall Laboratories, Ltd.1981-12-312003-09-11Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Klb 6 Tab 8.33mgtablet8.33 mgoralPure Life International Prods Inc.1992-12-312001-08-07Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Klb6 Tablets 17mgtablet17 mgoralGahler Enterprises Ltd.1988-12-312002-07-17Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Lgb-dtx Tab 10mgtablet10 mgoralMetagenics, Inc.1989-12-312002-10-07Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Linum B6 Tab 2mgtablet2 mgoralStandard Process Inc.Not applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Nutrol-B6 Tab 100mgtablet100 mgoralRolmex International Inc.1989-12-311997-08-08Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pyridoxen Tab 50mgtablet50 mgoralSantÉ Naturelle (Ag) LtÉe1987-12-311999-08-18Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pyridoxinetablet250 mgoralSeroyal International Inc.1988-12-312009-07-06Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pyridoxine HCl Tab 25mgtablet25 mgoralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1957-12-312002-07-31Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pyridoxine HCl Tab 25mgtablet25 mgoralSwiss Herbal Remedies Ltd.1971-12-312003-09-10Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pyridoxine HCl Tab 50mgtablet50 mgoralSwiss Herbal Remedies Ltd.1989-12-312004-09-03Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pyridoxine-S Tab 50mgtablet50 mgoralNutri West Products Ltd.1993-12-311997-08-05Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Super Klb6 Tab 17mgtablet17 mgoralAlbi Imports Ltd.1981-12-311996-09-09Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Super Klb6 Tab 17mgtablet17 mgoralCountry Health Laboratories Ltd.1981-12-312001-07-27Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vit B6 Pyridoxine HCl Tab 50mg USPtablet50 mgoralPure Life International Prods Inc.1992-12-312001-08-07Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vit B6 Tab 250mgtablet250 mgoralHall Laboratories, Ltd.1981-12-312003-09-11Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vita-doxine Cap 250mgcapsule250 mgoralLes Laboratoires Vachon Inc.1990-12-312001-08-07Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B-6 50 Mg Tablettablet50 mgoralGeneral Nutrition Canada Inc.1997-04-182005-08-05Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B-6 100mgcapsule100 mgoralNutraceutical Corporation2003-10-012007-08-02Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B-6 100mg Tabtablet100 mgoralPharmavite Llc1993-12-312006-07-05Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B-6 17mg Tabtablet17 mgoralPharmavite Llc1993-12-311998-09-08Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B-6 200mgcapsule200 mgoralNutraceutical Corporation2003-09-022006-08-02Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B-6 Tab 200mgtablet200 mgoralNutri West Products Ltd.1988-12-312002-06-14Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B6tablet250 mgoralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1983-12-312002-07-31Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B6 50mg Tabtablet50 mgoralNutricorp International1993-12-312009-08-05Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B6 100 mgcapsule100 mgoralHolista Health (Canada) Inc.2002-11-132008-07-17Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B6 100 Mg USPtablet100 mgoralAccurex Health Care Manufacturing Inc.2002-06-262009-07-31Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B6 100mgtablet100 mgoralGreat Earth Companies, Inc.1998-08-252002-10-02Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B6 100mg Caplettablet100 mgoralHealth Wise Nutrition Inc.1994-12-312002-07-18Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B6 100mg Tabtablet100 mgoralJamieson Laboratories Ltd1994-12-311996-09-10Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B6 200mgtablet200 mgoralGreat Earth Companies, Inc.1998-08-252002-10-02Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B6 50mgtablet50 mgoralGreat Earth Companies, Inc.1998-08-252002-10-02Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B6 Cap 250mgcapsule250 mgoralQuest Vitamins A Div Of Purity Life Health Products1980-12-312002-07-29Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B6 Capsules 100mgcapsule100 mgoralQuest Vitamins A Div Of Purity Life Health Products1989-12-312001-07-06Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B6 Capsules 3.5mgcapsule3.5 mgoralVita Health Products Inc1990-12-311997-08-18Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B6 Tab 100mgtablet100 mgoralCountry Health Laboratories Ltd.1982-12-312001-07-27Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B6 Tab 100mgtablet100 mgoralNutristar Health Products (1987) Inc.1983-12-311996-09-09Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B6 Tab 100mgtablet100 mgoralWampole Brands1979-12-312004-06-29Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B6 Tab 100mgtablet100 mgoralShoppers Drug Mart Inc.1980-12-311997-08-15Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B6 Tab 100mgtablet100 mgoralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1980-12-312002-07-31Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B6 Tab 100mg USPtablet100 mgoralAlive Vitamins1987-12-311997-08-11Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B6 Tab 250mgtablet250 mgoralVita Health Products Inc1985-12-312005-07-20Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B6 Tab 250mgtablet250 mgoralNutri Dyn Products Ltd.1976-12-311997-08-22Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B6 Tab 25mgtablet25 mgoralWampole Brands, A Division Of Pangeo Pharma (Canada) Inc.1978-12-312002-07-29Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B6 Tab 25mgtablet25 mgoralAlbi Naturals1979-12-312008-07-17Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B6 Tab 25mgtablet25 mgoralVita Health Products Inc1975-12-312002-07-31Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B6 Tab 25mgtablet25 mgoralAvacare, Division Of Jeunique International Inc.1985-12-311996-09-09Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B6 Tab 50mgtablet50 mgoralQuest Vitamins A Div Of Purity Life Health Products1977-12-312001-07-06Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B6 Tab 50mgtablet50 mgoralVita Health Products Inc1977-12-312008-08-05Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B6 Tab 50mgtablet50 mgoralNutristar Health Products (1987) Inc.1980-12-311996-09-09Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B6 Tablets 250mgtablet250 mgoralNu Life Nutrition Ltd.1987-12-312005-03-15Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamin B6 Tablets-250mgtablet250 mgoralDa Vinci Laboratories, Division Of Foodscience Corporation2002-06-172007-07-18Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamine B6 100 Mg - Tablettablet100 mgoralNobel Pharm Enr.1995-12-312001-10-15Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamine B6 100mgtablet100 mgoralGamme Nature1990-12-312004-07-26Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamine B6 25mg Comprimetablet25 mgoralBio Vita1988-03-231997-08-07Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamine B6 Tab 100mg USPtablet100 mgoralLaboratoire Lalco Inc.1986-12-312004-07-26Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamine B6 Tab 250mgtablet250 mgoralLes Produits Gerbex Inc.1985-12-311997-08-11Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamine B6 Tab 25mg USP Chewabletablet25 mgoralLab Gernetic Int Ltee1985-12-311997-02-21Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
International Brands
NameCompany
BecilanNot Available
BeesixNot Available
BenadonNot Available
BonasanitNot Available
Hexa-BetalinNot Available
HexobionNot Available
NestrexNot Available
Brand mixtures
NameLabellerIngredients
Acetabolan III Vitamin and Mineral SupplementIovate Health Sciences International Inc.
Acetabolan-II Vitamin and Mineral SupplementIovate Health Sciences International Inc.
Adrenogist TabPure Life International Prods Inc.
Animi-3PBM Pharmaceuticals, Inc
Animi-3 With Vitamin DPBM Pharmaceuticals, Inc
AntlervironClassical Remedia Ltd
Aqua-S SupplementGarden State Nutritionals
Av-vite FbAv Kare, Inc.
Avon Nutrivance Stress FormulaAvon Canada Ulc
B 6 PlusAnabolic Laboratories Inc.
B Complex TabletsGolden Neo Life Diamite International, Limited
B Complex W Vit C W Non-med Yeast&liver TabPharmavite Llc
B Complex With C 300mg TabPharmavite Llc
B Plus C 300mg Timed ReleaseVita Health Products Inc
B Stress C + Iron & ViteStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
B With C 500 CapPharmetics (2011) Inc
B-50 Complex TabVita Health Products Inc
B-complex TabletsShaklee Canada Inc
B-nexaUpsher Smith Laboratories, Inc.
B-plexLand Art Inc.
B-plex 100Merit Pharmaceutical
B50 B Complex TabNutristar Health Products (1987) Inc.
B6 Plus TabVita Health Products Inc
B6, B12 & Folic AcidNatural Factors Nutritional Products Ltd.
B6, B12 & Folic Acid Multi-vitamin TabletsWampole Brands
B6-niacinamide TabStandard Process Inc.
BaisixProdemdis Enr.
Balanced B-100 B-complex Vitamins TabPharmavite Llc
Balanced B-100 Timed ReleasePharmavite Llc
Balanced B-50 ComplexLeiner Health Products Inc.
Balanced B-complex Vit + Vit C&e TabPharmavite Llc
Beminal 500 TabsWyeth Canada
Beminal With C Fortis PwsWyeth Ayerst Canada Inc.
Bio-fenLisa & Gerry Freundl
Bio-gynThorne Research Inc.
C 106 TabNf Formulas Inc.
C-B ComplexAvacare, Division Of Jeunique International Inc.
C-forcePrairie Naturals
C.R.D.-forcePrairie Naturals
C.R.T. X Multivitamin & Mineral Powder MixMetaform Ltd.
Calcium Folic Acid Plus D ChewableAcella Pharmaceuticals, LLC
Carbassist TabletsWyeth Consumer Healthcare Inc.
Catalyn TabStandard Process Inc.
Cataplex F TabletsStandard Process Inc.
Cda-21 Vitamins With Non-medicinal Probiotic ComplexRx Vitamins Inc.
Cedevita Plus Vitamin SupplementPliva, Pharmaceutical, Chemical, Food And Cosmetic Industry, Inc.
Cedevita Sugar-free Vitamin SupplementPliva, Pharmaceutical, Chemical, Food And Cosmetic Industry, Inc.
Centrum Junior (chewable)Whitehall Robins Inc.
Centrum Junior Regular (chewable Tablets)Whitehall Robins Inc.
Chewable Children's Complete Multivitamins With Essential MineralsWn Pharmaceuticals Ltd.
Chewable MultivitaminsWn Pharmaceuticals Ltd.
Chewable Multivitamins Plus IronWn Pharmaceuticals Ltd.
Chewable Multivitamins With Extra CWn Pharmaceuticals Ltd.
Children Choice Multivit Chewable TabSwiss Herbal Remedies Ltd.
Children's Chewable Multi-vitaminWn Pharmaceuticals Ltd.
Children's Chewable Multi-vitamin Complete With MineralsWn Pharmaceuticals Ltd.
Children's Chewable Multiple VitaminsStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Children's Chewable Multivitamins With MineralsWn Pharmaceuticals Ltd.
Children's Vitamins ChewableVita Health Products Inc
Childrens Chewable Multiple Vitamins TabPharmavite Llc
Citranatal DHAMission Pharmacal Company
Citranatal Harmony 3.0Mission Pharmacal Company
Citranatal RxMission Pharmacal Company
Complex-75Frega Inc.
Complexe B-75Frega Inc.
Concept DHAUs Pharmaceutical Corporation
Concept ObUs Pharmaceutical Corporation
Daily Energy Brand B-complexEnzymatic Therapy (Canada) Inc.
Dermagran Moisturizing SprayCanadian Medical Supply Inc.
Dia-viteR & D Laboratories Inc.
DiaplexNephro Tech, Inc.
DiclegisDuchesnay Usa, Inc.
DivistaUs Pharmaceutical Corporation
E.V.C. Vitamins TabSisu Inc.
Ez-flexMetagenics, Inc.
Fabb TabletsMidlothian Laboratories
Fem - ControlMetagenics, Inc.
Fem - F.S. FormulaMetagenics, Inc.
Fem - PmtMetagenics, Inc.
Feminique W Iron and Calcium TabStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Ferra Naka Plus VitaminsNaka Sales Ltd.
Floradix Formula LiqFlora Manufacturing And Distributing Ltd.
Floravit - SyrFlora Manufacturing And Distributing Ltd.
FolbicNcs Health Care Of Ky, Inc Dba Vangard Labs
FolcapsMidlothian Laboratories
Folcaps Care OneMidlothian Laboratories
Folcaps Omega-3Midlothian Laboratories
Folic Acid PlusVita Health Products Inc
Foltabs 800Midlothian Laboratories
For Kids Only Chewable MultivitaminsStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Formula 6100 CapStandard Process Inc.
Formula Ch. Les.Abundance Marketing Ltd.
Formula CnBalance Plus, Inc.
Formula D.S.Golden Pride International
Formula Est'ro Tab SupportBalance Plus, Inc.
Formula Fm Vitamins & Minerals TabMetagenics, Inc.
Formula R TabMetagenics, Inc.
Formula Sf-710Thorne Research Inc.
Formula WbNutrivention Nutritional Products
Geritol LiquidGlaxosmithkline Consumer Healthcare Inc.
H. Formula - TabAbundance Marketing Ltd.
Hemenatal ObWh Nutritionals, Llc
Hi Potency Balanced B-100 Complex - TabLeiner Health Products Inc.
Hill.viteHillestad Pharmaceuticals Usa
Homosistrol CapsulesMacromed Pharmicia Inc.
Homosistrox CapsulesS.A.F. Nutritional Products Inc.
IfbVisiontel
Integra PlusUs Pharmaceutical Corporation
Iron Vitamins B6,b12,c,folic Acid TabLaboratoire Lalco Inc.
Isotamine B 300Valeant Canada Lp Valeant Canada S.E.C.
Isotonix Advanced B-complex Vitamins With Potassium and MagnesiumMarket America, Inc.
Junior Multi Vitamins - RegularVita Health Products Inc
Kanga Sport Vitamins B & C Plus MineralsLacombe Drugs (1992) Ltd
Kanga-B Vitamin B Group + CLacombe Drugs (1992) Ltd
Kanga-kid Multi-vitamin & MineralLacombe Drugs (1992) Ltd
Kanga-kid Vitamins & IronLacombe Drugs (1992) Ltd
Kid's Choice Children's Chewable Vitamins - TabVita Health Products Inc
Kidmag Vitamins W Magnesium TabMetagenics, Inc.
Kids Stuff TabletsVita Health Products Inc
Kids Stuff With Iron TabletsVita Health Products Inc
Kimchi Vitamin Chewable MultivitaminTobico
Kmg PlusSeroyal International Inc.
Leritone JuniorInstitut De Recherche Biologique Yves Ponroy Canada Inc.
LipovitanP.S.W.C. Co., Inc.
Livron Plus AmpouleMedic Laboratory LtÉe
Magnesium 50mg With Vitamin B6 TabJamieson Laboratories Ltd
Megavites TabIcn Canada Ltd.
Meth-X Vitamin and Mineral SupplementDymatize Enterprises Inc.
Methyl-plexThorne Research Inc.
Min-chex CapStandard Process Inc.
Mnps Formula SupplementGarden State Nutritionals
Multi #2W 7 Clay Inc.
Multi Vitamin & MineralsWn Pharmaceuticals Ltd.
Multi Vitamin and FluorideLibertas Pharma, Inc.
Multi Vitamin Drops With FluorideSeton Pharmaceuticals
Multi Vitamin Drops With Fluoride and IronSeton Pharmaceuticals
Multi Vitamin Drops With Fluoride With IronStratus Pharmaceuticals
Multi Vitamin Plus IronWn Pharmaceuticals Ltd.
Multi Vitamin, Iron and FluorideLibertas Pharma, Inc.
Multi-vitaminLLC Federal Solutions
Multi-vitamin FluorideStratus Pharmaceuticals
Multi-vitamin Fluoride and Iron DropsBoca Pharmacal, LLC
Multi-vitamin Fluoride DropsH.J. Harkins Company, Inc.
Multi-vitamin With FluorideGolden State Medical Supply, Inc.
Multi-vitaminsWn Pharmaceuticals Ltd.
Multi-vitamins for Infusion LiqDavid Bull Laboratories (Pty) Ltd.
Multiple VitaminsGfr Pharma Ltd.
Multivit-liqPharmalab Inc.
MultivitaminLaboratoires Confab Inc
Multivitamines Plus C Pour Enfants (chewable Tablets)Laboratoire Lalco Inc.
Multivitamines Plus Fer Pour Enfants (chewable Tablets)Laboratoire Lalco Inc.
Multivitamines Pour Enfants (chewable Tablets)Laboratoire Lalco Inc.
Multivitamins for ChildrenQuest Vitamins A Div Of Purity Life Health Products
MvcSancilio & Company Inc
Mvc-fluorideSancilio & Company Inc.
Mynephrocaps Dialysis/stress Vitamin SupplementMartin Ekwealor Pharmaceuticals, Inc.
Nata KompleteWh Nutritionals, Llc
Natelle OneMEDA Pharmaceuticals
Neo Bex ElixirNeolab Inc
Neo-bexNeolab Inc
NephrocapsCardinal Health
Nexa PlusUpsher Smith Laboratories, Inc.
Nexa Select Rx Prenatal Vitamin With Plant-based DHAUpsher Smith Laboratories, Inc.
Ni-C-E-LE PlusNutrimetics International (Canada) Inc.
Niaacinamide Azelaic Ac Turmer Fa B6 Zinc Ox CopperVirtus Pharmaceuticals LLC
Niacex B6Therapeutic Foods Co.
Niacinamide-B6 CapStandard Process Inc.
Nutrol-B-complexRolmex International Inc.
O-cal Prenatal VitaminPharmics, Inc.
P & Sp Special FormulaNutraceutical Corporation
Perioe Lucky Fresh - Cavity CareLG Household and Healthcare, Inc.
Phosthenine Vitamines Et Fer (ampoules Buvable)Laboratoires Cortunon Inc.
Polymine Avec Zinc Et CuivreLes Laboratoires Vachon Inc.
Prefera Ob Plus DHAAlaven Pharmaceutical LLC
PreferaobMEDA Pharmaceuticals
Preferaob Plus DHAAlaven Pharmaceutical LLC
PremelLe Naturiste J.M.B. Inc.
Prenatal Mega AntioxidantUsana Health Services, Inc.
Prenatal Vitamins Plusbryant ranch prepack
Prenate AmAvion Pharmaceuticals, Llc
Prenate StarAvion Pharmaceuticals, Llc
Prevital TabBio Vita
Pros-gard Zinc and Vitamin B6 - CapsuleHolista Health (Canada) Inc.
ProsgardHolista Health (Canada) Inc.
Purevit Dualfe PlusPure Tek Corporation
Reaphirm Plant Source DHAEverett Laboratories, Inc.
Red BullP.S.W.C. Co., Inc.
Redoxon-calBayer Inc Consumer Care
ReebokClearly Canadian Beverage Corporation
Reliv So Sense Daily Vitamin SupplementReliv International Inc.
Reno CapsNnodum Pharmaceuticals
ReplaviteStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
RogenicEnzymatic Therapy (Canada) Inc.
Se-tan DHASeton Pharmaceuticals
Se-tan PlusSeton Pharmaceuticals
Shen Min Vitamin SupplementBiotech Corporation
SolarayAhmed's Sunforce International Products Inc.
Somarexin and C 1000Laboratoire Lalco Inc.
Sopalamine/3b TabTechnilab Pharma Inc.
Stress B Complex With C, E & IronPharmavite Llc
Stress Complex 600 Avec Vit E Cuivre ZincFrega Inc.
Stress FormulaVita Health Products Inc
Stress Formula + IronVita Health Products Inc
Stress Formula Multivitamin Tablets USPLeiner Health Products Inc.
Stress Formula TabNature's Sunshine Products Of Canada Ltd.
Stress Tab With Iron and Vitamin EVita Health Products Inc
Stress Tab With Zinc, Copper and Vitamin EVita Health Products Inc
Stressease Plus Vitamins and MineralsJamieson Laboratories Ltd
Strovite Forte CapletEverett Laboratories, Inc.
Strovite One CapletsEverett Laboratories, Inc.
Super PantoplexNu Life Nutrition Ltd.
Super Vitalex Ampoule BuvableCarmaran LtÉe
Supravite 10ml AmpouleNobel Pharm Enr.
Supravite Bouteille 250mlNobel Pharm Enr.
Supravite C 1000Nobel Pharm Enr.
Supravite Stress Avec Vit EPharmalab Inc.
Supravite Stress Avec Vit E Cuivre Et ZincPharmalab Inc.
Supravite Stress Avec Vit E Et FerPharmalab Inc.
Swical-energy-2Les Laboratoires Swisse Inc.
T.R.I. B-plex SrcAnabolic Laboratories Inc.
Tandem DHAUs Pharmaceutical Corporation
Tandem ObUs Pharmaceutical Corporation
Tandem PlusUs Pharmaceutical Corporation
Tar-endNature's Sunshine Products Inc.
Toni Com LiqVitalab
TozalFocus Laboratories, Inc.
Tri AdrenopanAnabolic Laboratories Inc.
Ultra EnerforceNutribon (1986) Inc.
V-natalVirtus Pharmaceuticals
Vigo Multivitamins Drops/lozengeAshbury Research Corporation
Virt-bal DHA PlusVirtus Pharmaceuticals
Virt-capsVirtus Pharmaceuticals LLC
Virt-PNVirtus Pharmaceuticals
Virt-PN PlusVirtus Pharmaceuticals LLC
Virt-viteVirtus Pharmaceuticals LLC
Virt-vite PlusVirtus Pharmaceuticals LLC
Vita-B-75 CapLes Laboratoires Vachon Inc.
Vitabanks Vitamin TabVitabank Inc.
Vitafer - LiqFrega Inc.
Vitafol CapletEverett Laboratories, Inc.
Vitafol NanoEverett Laboratories, Inc.
Vitafol Ob CapletEverett Laboratories, Inc.
Vitafol OneEverett Laboratories, Inc.
Vitafol PlusEverett Laboratories, Inc.
Vitamin B ComplexMylan Institutional LLC
Vitamin B Complex Plus C 300mg Timed ReleaseVita Health Products Inc
Vitamin B Complex TabNutristar Health Products (1987) Inc.
Vitamin B Compound TabNutrilite, A Division Of Access Business Group, Llc
Vitamin B6 & B12 With Folic AcidWn Pharmaceuticals Ltd.
Vitamine Du Groupe B Plus Fer - LiqPharmalab Inc.
Vitamines Pour Bebes Et EnfantsHerbes Universelles Inc.
VitamuneNu Skin Canada, Inc.
Vitogen B Compound W C Fortis CapsulesStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Vitogen B Stress C Vit E Zinc & CopStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Vp-ggr-B6Virtus Pharmaceuticals
Vp-heme ObVirtus Pharmaceuticals LLC
Vp-heme OneVirtus Pharmaceuticals LLC
Vp-zelVirtus Pharmaceuticals
Z-force Vitamin and Mineral SupplementDymatize Enterprises Inc.
Z-mass PM Vitamin and Mineral SupplementCytodyne Technologies Inc.
Zinc Plus Vitamin B6 TabMetagenics, Inc.
Zinc Plus Vitamins C & B6 LozengesVita Plus Industries Inc.
ZingiberPru Gen, Inc. Pharmaceuticals
Salts
Name/CASStructureProperties
Pyridoxine hydrochloride
58-56-0
Thumb
  • InChI Key: ZUFQODAHGAHPFQ-UHFFFAOYSA-N
  • Monoisotopic Mass: 205.050570962
  • Average Mass: 205.639
DBSALT000151
Categories
UNIIKV2JZ1BI6Z
CAS number65-23-6
WeightAverage: 169.1778
Monoisotopic: 169.073893223
Chemical FormulaC8H11NO3
InChI KeyInChIKey=LXNHXLLTXMVWPM-UHFFFAOYSA-N
InChI
InChI=1S/C8H11NO3/c1-5-8(12)7(4-11)6(3-10)2-9-5/h2,10-12H,3-4H2,1H3
IUPAC Name
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol
SMILES
CC1=C(O)C(CO)=C(CO)C=N1
Taxonomy
DescriptionThis compound belongs to the class of organic compounds known as pyridoxines. These are pyridoxal derivatives in which the carbaldehyde group at position 2 of the pyridoxal moiety is replaced by a hydroxymethyl group.
KingdomOrganic compounds
Super ClassOrganoheterocyclic compounds
ClassPyridines and derivatives
Sub ClassPyridoxines
Direct ParentPyridoxines
Alternative Parents
Substituents
  • Pyridoxine
  • Methylpyridine
  • Hydroxypyridine
  • Heteroaromatic compound
  • Azacycle
  • Hydrocarbon derivative
  • Aromatic alcohol
  • Primary alcohol
  • Organooxygen compound
  • Organonitrogen compound
  • Alcohol
  • Aromatic heteromonocyclic compound
Molecular FrameworkAromatic heteromonocyclic compounds
External Descriptors
Pharmacology
IndicationFor the treatment of vitamin B6 deficiency and for the prophylaxis of isoniazid-induced peripheral neuropathy.
PharmacodynamicsVitamin B6 (pyridoxine) is a water-soluble vitamin used in the prophylaxis and treatment of vitamin B6 deficiency and peripheral neuropathy in those receiving isoniazid (isonicotinic acid hydrazide, INH). Vitamin B6 has been found to lower systolic and diastolic blood pressure in a small group of subjects with essential hypertension. Hypertension is another risk factor for atherosclerosis and coronary heart disease. Another study showed pyridoxine hydrochloride to inhibit ADP- or epinephrine-induced platelet aggregation and to lower total cholesterol levels and increase HDL-cholesterol levels, again in a small group of subjects. Vitamin B6, in the form of pyridoxal 5'-phosphate, was found to protect vascular endothelial cells in culture from injury by activated platelets. Endothelial injury and dysfunction are critical initiating events in the pathogenesis of atherosclerosis. Human studies have demonstrated that vitamin B6 deficiency affects cellular and humoral responses of the immune system. Vitamin B6 deficiency results in altered lymphocyte differentiation and maturation, reduced delayed-type hypersensitivity (DTH) responses, impaired antibody production, decreased lymphocyte proliferation and decreased interleukin (IL)-2 production, among other immunologic activities.
Mechanism of actionVitamin B6 is the collective term for a group of three related compounds, pyridoxine (PN), pyridoxal (PL) and pyridoxamine (PM), and their phosphorylated derivatives, pyridoxine 5'-phosphate (PNP), pyridoxal 5'-phosphate (PLP) and pyridoxamine 5'-phosphate (PMP). Although all six of these compounds should technically be referred to as vitamin B6, the term vitamin B6 is commonly used interchangeably with just one of them, pyridoxine. Vitamin B6, principally in its biologically active coenzyme form pyridoxal 5'-phosphate, is involved in a wide range of biochemical reactions, including the metabolism of amino acids and glycogen, the synthesis of nucleic acids, hemogloblin, sphingomyelin and other sphingolipids, and the synthesis of the neurotransmitters serotonin, dopamine, norepinephrine and gamma-aminobutyric acid (GABA).
AbsorptionThe B vitamins are readily absorbed from the gastrointestinal tract, except in malabsorption syndromes. Pyridoxine is absorbed mainly in the jejunum.
Volume of distributionNot Available
Protein binding22%
Metabolism

Hepatic.

Route of eliminationNot Available
Half life15-20 days
ClearanceNot Available
ToxicityOral Rat LD50 = 4 gm/kg. Toxic effects include convulsions, dyspnea, hypermotility, diarrhea, ataxia and muscle weakness.
Affected organisms
  • Humans and other mammals
PathwaysNot Available
SNP Mediated EffectsNot Available
SNP Mediated Adverse Drug ReactionsNot Available
ADMET
Predicted ADMET features
PropertyValueProbability
Human Intestinal Absorption+0.9728
Blood Brain Barrier+0.6889
Caco-2 permeable-0.8958
P-glycoprotein substrateNon-substrate0.5579
P-glycoprotein inhibitor INon-inhibitor0.9723
P-glycoprotein inhibitor IINon-inhibitor0.9221
Renal organic cation transporterNon-inhibitor0.8177
CYP450 2C9 substrateNon-substrate0.7386
CYP450 2D6 substrateNon-substrate0.781
CYP450 3A4 substrateNon-substrate0.7104
CYP450 1A2 substrateNon-inhibitor0.9046
CYP450 2C9 inhibitorNon-inhibitor0.9071
CYP450 2D6 inhibitorNon-inhibitor0.923
CYP450 2C19 inhibitorNon-inhibitor0.9025
CYP450 3A4 inhibitorNon-inhibitor0.8648
CYP450 inhibitory promiscuityLow CYP Inhibitory Promiscuity0.695
Ames testNon AMES toxic0.9133
CarcinogenicityNon-carcinogens0.9418
BiodegradationNot ready biodegradable0.5678
Rat acute toxicity1.6573 LD50, mol/kg Not applicable
hERG inhibition (predictor I)Weak inhibitor0.8454
hERG inhibition (predictor II)Non-inhibitor0.8734
ADMET data is predicted using admetSAR, a free tool for evaluating chemical ADMET properties. (23092397 )
Pharmacoeconomics
Manufacturers
  • Eli lilly and co
  • Akorn inc
  • App pharmaceuticals llc
  • Bel mar laboratories inc
  • Dell laboratories inc
  • Elkins sinn div ah robins co inc
  • Luitpold pharmaceuticals inc
  • Watson laboratories inc
Packagers
Dosage forms
FormRouteStrength
Tabletoral250 mg
Tablet (extended-release)oral
Tablet (extended-release)oral500 mg
Injection, solutionintramuscular; intravenous
Tablet (extended-release)400 mg
Powder for solutionintravenous
Powderoral
Waferoral
Tabletoral2 mg
Tabletoral
Spraytopical
Tablet, delayed releaseoral
Syruporal
Tabletoral8.45 mg
Tabletoral6 mg
Tabletoral8.33 mg
Tabletoral10 mg
Solution/ dropsoral
Liquidoral
Solutionoral
Liquidintravenous
Tablet, chewableoral
Capsule, gelatin coatedoral
Elixiroral
Capsuleoral
Pastedental
Tablet, coatedoral
Liquidintramuscular; intravenous100 mg
Tablet100 mg
Injection, solutionintramuscular; intravenous100 mg/mL
Solutionintramuscular; intravenous100 mg
Tablet (effervescent)oral
Powder for solutionoral
Liquid; tabletoral
Capsule (sustained-release)oral
Kit
Tablet (extended-release)100 mg
Tabletoral50 mg
Capsuleoral250 mg
Tablet
Capsule, liquid filledoral
Injectionintravenous
Capsuleoral100 mg
Tabletoral17 mg
Capsuleoral200 mg
Tabletoral200 mg
Capsuleoral3.5 mg
Tabletoral100 mg
Tabletoral25 mg
Tablet, film coatedoral
Lozengeoral
Prices
Unit descriptionCostUnit
Pyridoxine HCl 100 50 mg tablet Bottle12.99USD bottle
Pyridoxine HCl 100 mg/ml vial11.69USD vial
Pyridoxine 100 mg/ml vial10.79USD ml
Pyridoxine hcl crystals6.94USD g
Pyridoxine 500 mg tablet0.18USD tablet
Pyridoxine 25 mg tablet0.14USD tablet
Neuro k 500 mg tablet0.13USD tablet
Pyridoxine 250 mg tablet0.13USD tablet
CVS Pharmacy vitamin b-6 200 mg tablet0.07USD tablet
Neuro-k 250 mg tablet0.06USD tablet
Pyridoxine 50 mg tablet0.06USD tablet
Vitamin b-6 100 mg tablet0.04USD tablet
CVS Pharmacy vitamin b-6 100 mg tablet0.03USD tablet
Pyridoxine 100 mg tablet0.03USD tablet
Vitamin b6 50 mg tablet0.03USD tablet
Vitamin b-6 50 mg tablet0.03USD tablet
CVS Pharmacy vitamin b-6 50 mg tablet0.02USD tablet
Vitamin b-6 25 mg tablet0.02USD tablet
DrugBank does not sell nor buy drugs. Pricing information is supplied for informational purposes only.
PatentsNot Available
Properties
StateSolid
Experimental Properties
PropertyValueSource
melting point159-162 °CPhysProp
water solubility2.2E+005 mg/LNot Available
logP-0.77SANGSTER (1993)
Predicted Properties
PropertyValueSource
Water Solubility16.1 mg/mLALOGPS
logP-0.57ALOGPS
logP-0.95ChemAxon
logS-1ALOGPS
pKa (Strongest Acidic)9.4ChemAxon
pKa (Strongest Basic)5.58ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count4ChemAxon
Hydrogen Donor Count3ChemAxon
Polar Surface Area73.58 Å2ChemAxon
Rotatable Bond Count2ChemAxon
Refractivity44.11 m3·mol-1ChemAxon
Polarizability17.11 Å3ChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Mass Spec (NIST)Not Available
Spectra
Spectrum TypeDescriptionSplash Key
GC-MSGC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (3 TMS)splash10-3zf1000000-30b4702623a6d8fcb4bbView in MoNA
GC-MSGC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies)splash10-2pz0000000-0581e2b42fa48c1ea498View in MoNA
GC-MSGC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (3 TMS)splash10-zbe0000000-32929ff06762b9f5887fView in MoNA
GC-MSGC-MS Spectrum - GC-MS (3 TMS)splash10-3hz2000000-34a09ddbbb462aeb02a6View in MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 10V, Positive (Annotated)splash10-0z00000000-bd0de86c072765a5caadView in MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 25V, Positive (Annotated)splash10-ez00000000-2018b406a3c75213b733View in MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 40V, Positive (Annotated)splash10-z700000000-e69bb531deb2a103a476View in MoNA
LC-MS/MSLC-MS/MS Spectrum - EI-B (HITACHI M-80) , Positivesplash10-zh00000000-77c43a946c4ae1abf3b9View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, Negativesplash10-0z00000000-479d4492cc8d634fa366View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 20V, Negativesplash10-0z00000000-486d6a4e5e1a731b7c54View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 30V, Negativesplash10-2z00000000-4ef09ce9c04561a1085eView in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 40V, Negativesplash10-4z00000000-3298adf6db36689d5d43View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 50V, Negativesplash10-rz00000000-6711954ee96f08344434View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, Positivesplash10-0z00000000-234e90d43a7febd7a098View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 20V, Positivesplash10-0z00000000-137080765c0035b45258View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 30V, Positivesplash10-3z00000000-882ee900a8bba08e2c7cView in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 40V, Positivesplash10-wz00000000-e0e11797b63cea991d81View in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 50V, Positivesplash10-z700000000-c25384179219411af02cView in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QTOF (UPLC Q-Tof Premier, Waters) , Positivesplash10-0z00000000-c0e149ce890192397b7fView in MoNA
LC-MS/MSLC-MS/MS Spectrum - LC-ESI-QTOF (UPLC Q-Tof Premier, Waters) , Negativesplash10-0z00000000-f9f378af3d47ab006806View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-0z00000000-eab5b3411261744df750View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-0z00000000-cc4dc8719602182ef1ebView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-lz00000000-1c2637733578fcdd7c6aView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-1z00000000-e89cc69d8b21012ff982View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-1z00000000-0ad8d09e042015cb2e33View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-zm00000000-577a3d87899ca47d539fView in MoNA
MSMass Spectrum (Electron Ionization)splash10-qz00000000-1237eaf82dfadfd54d4bView in MoNA
1D NMR1H NMR SpectrumNot Available
2D NMR[1H,1H] 2D NMR SpectrumNot Available
2D NMR[1H,13C] 2D NMR SpectrumNot Available
References
Synthesis Reference

Harumi Kita, “Production of pyridoxine.” U.S. Patent US4339586, issued October, 1972.

US4339586
General ReferencesNot Available
External Links
ATC CodesNot Available
AHFS Codes
  • 88:08.00
  • 92:02.00*
PDB Entries
FDA labelNot Available
MSDSDownload (51.5 KB)
Interactions
Drug Interactions
Drug
AltretamineThe therapeutic efficacy of Altretamine can be decreased when used in combination with Pyridoxine.
AmobarbitalThe metabolism of Amobarbital can be increased when combined with Pyridoxine.
ButabarbitalThe metabolism of Butabarbital can be increased when combined with Pyridoxine.
ButethalThe metabolism of Butethal can be increased when combined with Pyridoxine.
FosphenytoinThe metabolism of Fosphenytoin can be increased when combined with Pyridoxine.
HeptabarbitalThe metabolism of Heptabarbital can be increased when combined with Pyridoxine.
HexobarbitalThe metabolism of Hexobarbital can be increased when combined with Pyridoxine.
LevodopaThe therapeutic efficacy of Levodopa can be decreased when used in combination with Pyridoxine.
MethohexitalThe metabolism of Methohexital can be increased when combined with Pyridoxine.
PentobarbitalThe metabolism of Pentobarbital can be increased when combined with Pyridoxine.
PhenobarbitalThe metabolism of Phenobarbital can be increased when combined with Pyridoxine.
PhenytoinThe metabolism of Phenytoin can be increased when combined with Pyridoxine.
PrimidoneThe metabolism of Primidone can be increased when combined with Pyridoxine.
SecobarbitalThe metabolism of Secobarbital can be increased when combined with Pyridoxine.
Food InteractionsNot Available

Targets

1. Pyridoxal kinase

Kind: Protein

Organism: Human

Pharmacological action: yes

Actions: ligand

Components

Name UniProt ID Details
Pyridoxal kinase O00764 Details

References:

  1. Adams JB, George F, Audhya T: Abnormally high plasma levels of vitamin B6 in children with autism not taking supplements compared to controls not taking supplements. J Altern Complement Med. 2006 Jan-Feb;12(1):59-63. Pubmed
  2. Newman JA, Das SK, Sedelnikova SE, Rice DW: The crystal structure of an ADP complex of Bacillus subtilis pyridoxal kinase provides evidence for the parallel emergence of enzyme activity during evolution. J Mol Biol. 2006 Oct 20;363(2):520-30. Epub 2006 Aug 12. Pubmed
  3. Kim SY, An JJ, Kim DW, Choi SH, Lee SH, Hwang SI, Kwon OS, Kang TC, Won MH, Cho SW, Park J, Eum WS, Lee KS, Choi SY: Tat-mediated protein transduction of human brain pyridoxine-5-P oxidase into PC12 cells. J Biochem Mol Biol. 2006 Jan 31;39(1):76-83. Pubmed
  4. Nagahashi Y, Tazoe M, Hoshino T: Cloning of the pyridoxine 5’-phosphate phosphatase gene (pdxP) and vitamin B6 production in pdxP recombinant Sinorhizobium meliloti. Biosci Biotechnol Biochem. 2008 Feb;72(2):421-7. Epub 2008 Feb 7. Pubmed

Enzymes

1. Cytochrome P450 1A1

Kind: Protein

Organism: Human

Pharmacological action: no

Actions: inhibitor

Components

Name UniProt ID Details
Cytochrome P450 1A1 P04798 Details

References:

  1. Tangjarukij C, Navasumrit P, Zelikoff JT, Ruchirawat M: The effects of pyridoxine deficiency and supplementation on hematological profiles, lymphocyte function, and hepatic cytochrome P450 in B6C3F1 mice. J Immunotoxicol. 2009 Sep;6(3):147-60. doi: 10.1080/15476910903083866. Pubmed

Comments
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Drug created on June 13, 2005 07:24 / Updated on September 24, 2013 13:55