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Displaying drugs 176 - 200 of 2005 in total
DrugBank ID Name Weight StructureCategoriesTherapeutic Indication
DB01132
111025-46-8
Pioglitazone356.439

C19H20N2O3S
ThumbHypoglycemic Agents / Blood Glucose Lowering Drugs, Excl. Insulins / Drugs Used in Diabetes / Thiazolidinediones / Cytochrome P-450 CYP2C9 Substrates / Cytochrome P-450 CYP2C9 Inhibitors / Cytochrome P-450 CYP2C8 Substrates / Cytochrome P-450 CYP2C8 Inhibitors / Cytochrome P-450 CYP3A Inducers / Combined Inducers of CYP3A4 and P-glycoprotein / Blood Glucose Lowering Agents / CYP3A4 Inducers (Weak) / Cytochrome P-450 CYP2C8 Inhibitors (moderate) / Cytochrome P-450 CYP2D6 Inhibitors / Cytochrome P-450 CYP2C19 Inhibitors / Cytochrome P-450 CYP3A4 Substrates / Alimentary Tract and Metabolism / Pharmacologic Actions / Chemical Actions and Uses / Physiological Effects of Drugs / Combinations of oral blood glucose lowering drugs / Combinations of oral blood glucose lowering drugs / Thiazolidinediones / Combinations of oral blood glucose lowering drugs / Combinations of oral blood glucose lowering drugsTreatment of Type II diabetes mellitus
DB00511
1111-39-3
Acetyldigitoxin806.9757

C43H66O14
ThumbDigitoxin / Cardenolides / Cardiac Glycosides / Cardanolides / Steroids / Glycosides / Carbohydrates / Digitalis Glycosides / Anti-Arrhythmia Agents / Cardiotonic Agents / Cardiac Therapy / Enzyme Inhibitors / Cardiovascular Agents / Cardiovascular System / Molecular Mechanisms of Pharmacological Action / Protective Agents / Specialty Uses of Chemicals / Polycyclic Compounds / Physiological Effects of Drugs / Pharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / Digitalis glycosidesUsed for fast digitalization in congestive heart failure.
DB00744
111406-87-2
Zileuton236.29

C11H12N2O2S
ThumbEnzyme Inhibitors / Analgesics, Non-Narcotic / Sensory System Agents / Peripheral Nervous System Agents / Antirheumatic Agents / Anti-Inflammatory Agents / Anti-Inflammatory Agents, Non-Steroidal / Hormones, Hormone Substitutes, and Hormone Antagonists / Hormone Antagonists / Cytochrome P-450 CYP1A2 Inhibitors / Lipoxygenase Inhibitors / Leukotriene Antagonists / Analgesics / Molecular Mechanisms of Pharmacological Action / Pharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / Physiological Effects of Drugs / Central Nervous System Agents / Cytochrome P-450 CYP1A2 Substrates / Cytochrome P-450 CYP2C9 Substrates / Cytochrome P-450 CYP3A4 SubstratesFor the prophylaxis and chronic treatment of asthma in adults and children 12 years of age and older.
DB01224
111974-69-7
Quetiapine383.507

C21H25N3O2S
ThumbHeterocyclic Compounds, 1-Ring / Sulfur Compounds / Inorganic Chemicals / Organic Chemicals / Psychotropic Drugs / Tranquilizing Agents / Central Nervous System Depressants / Antipsychotic Agents / Dibenzothiazepines / Thiazepines / Azepines / Thiepins / Nervous System / Psycholeptics / Diazepines, Oxazepines, Thiazepines and Oxepines / Alpha1 Antagonists / Antipsychotic Agents (Second Generation [Atypical]) / Hyperglycemia-Associated Agents / Heterocyclic Compounds, 3-Ring / Hypotensive Agents / Physiological Effects of Drugs / Central Nervous System Agents / Heterocyclic Compounds / Cytochrome P-450 CYP2D6 Inhibitors / Cytochrome P-450 CYP2D6 Substrates / Cytochrome P-450 CYP2C19 Substrates / Cytochrome P-450 CYP3A4 Substrates / P-glycoprotein/ABCB1 Substrates / Highest Risk QTc-Prolonging Agents / Pharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / Diazepines, oxazepines, thiazepines and oxepinesFor the treatment of schizophrenia and related psychotic disorders.
DB06824
112-24-3
Triethylenetetramine146.2339

C6H18N4
ThumbSpecialty Uses of Chemicals / Amines / Polyamines / Diamines / Sequestering Agents / Chelating Agents / Ethylenediamines / Organic Chemicals / Molecular Mechanisms of Pharmacological Action / Pharmacologic Actions / Chemical Actions and UsesNot Annotated
DB04224
112-80-1
Oleic Acid282.4614

C18H34O2
ThumbFatty Acids, Unsaturated / Fatty Acids / Fatty Acids, Monounsaturated / Oleic Acids / Lipids
DB06413
112111-43-0
Armodafinil273.35

C15H15NO2S
ThumbCentral Nervous System Stimulants / Cytochrome P-450 CYP3A Inducers / Cytochrome P-450 CYP1A2 Inducers / Wakefulness-Promoting Agents / Centrally Acting Sympathomimetics / Psychostimulants, Agents Used for Adhd and Nootropics / CYP3A4 Inducers (Weak) / Combined Inducers of CYP3A4 and P-glycoprotein / Cytochrome P-450 CYP2B6 Inducers / Central Nervous System Agents / Cytochrome P-450 CYP2C19 Inhibitors / Nervous System / Psychoanaleptics / Cytochrome P-450 CYP2C19 Inhibitors (moderate) / Cytochrome P-450 CYP2C9 Inhibitors / Pharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / Physiological Effects of Drugs / Centrally acting sympathomimeticsInvestigated for use/treatment in sleep disorders, obstructive sleep apnea, schizophrenia and schizoaffective disorders, depression, and bipolar di...
DB01764
112362-50-2
Dalfopristin690.847

C34H50N4O9S
ThumbCYP3A4 Inhibitors (Weak) / Cytochrome P-450 CYP3A Inhibitors / Combined Inhibitors of CYP3A4 and P-glycoprotein / Anti-Infective Agents / Therapeutic Uses / Pharmacologic Actions / Chemical Actions and Uses / Anti-Bacterial AgentsFor the treatment of bacterial infections (usually in combination with quinupristin).
DB01006
112809-51-5
Letrozole285.3027

C17H11N5
ThumbHormones, Hormone Substitutes, and Hormone Antagonists / Hormone Antagonists / Steroid Synthesis Inhibitors / Estrogen Antagonists / Aromatase Inhibitors / Endocrine Therapy / Hormone Antagonists and Related Agents / Cytochrome P-450 CYP2A6 Substrates / Cytochrome P-450 CYP2A6 Inhibitors / Enzyme Inhibitors / Antineoplastic Agents / Antineoplastic and Immunomodulating Agents / Molecular Mechanisms of Pharmacological Action / Pharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / Physiological Effects of Drugs / Cytochrome P-450 CYP3A4 Substrates / Aromatase inhibitorsFor the extended adjuvant treatment of early breast cancer in postmenopausal women who have received 5 years of adjuvant tamoxifen therapy. Also fo...
DB01044
112811-59-3
Gatifloxacin375.3941

C19H22FN3O4
ThumbAntineoplastic Agents / Anti-Infective Agents / Anti-Bacterial Agents / Topoisomerase Inhibitors / Topoisomerase II Inhibitors / Fluoroquinolones / Ophthalmologicals / Sensory Organs / Antiinfectives / Quinolone Antibacterials / Antibacterials for Systemic Use / Antiinfectives for Systemic Use / Enzyme Inhibitors / Molecular Mechanisms of Pharmacological Action / Pharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / FluoroquinolonesFor the treatment of bronchitis, sinusitis, community-acquired pneumonia, and skin infections (abscesses, wounds) caused by S. pneumoniae, H. influ...
DB00293
112887-68-0
Raltitrexed458.488

C21H22N4O6S
ThumbFolic Acid Antagonists / Thymidylate Synthase, antagonists & inhibitors / Antimetabolites, Antineoplastic / Folic Acid Analogues / Myelosuppressive Agents / Antineoplastic Agents / Antineoplastic and Immunomodulating Agents / Enzyme Inhibitors / Molecular Mechanisms of Pharmacological Action / Noxae / Toxic Actions / Antimetabolites / Pharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / Folic acid analoguesFor the treatment of malignant neoplasm of colon and rectum
DB02300
112965-21-6
Calcipotriol412.6047

C27H40O3
ThumbAntineoplastic Agents / Antipsoriatics for Topical Use / Antipsoriatics / Dermatologic Agents / Pharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / Dermatologicals / Other antipsoriatics for topical use / Other antipsoriatics for topical useFor the treatment of moderate plaque psoriasis in adults.
DB00536
113-00-8
Guanidine59.0705

CH5N3
ThumbGuanidines / Amidines / Organic ChemicalsFor the reduction of the symptoms of muscle weakness and easy fatigability associated with the myasthenic syndrome of Eaton-Lambert. It is not indi...
DB00696
113-15-5
Ergotamine581.6615

C33H35N5O5
ThumbReproductive Control Agents / Oxytocics / Serotonin Agents / Adrenergic Agents / Adrenergic alpha-Agonists / Adrenergic Agonists / Adrenergic alpha-1 Receptor Agonists / Serotonin Receptor Agonists / Cytochrome P-450 CYP1A2 Substrates / Cardiovascular Agents / Physiological Effects of Drugs / Analgesics, Non-Narcotic / Analgesics / Sensory System Agents / Peripheral Nervous System Agents / Central Nervous System Agents / Neurotransmitter Agents / Vasoconstrictor Agents / Heterocyclic Compounds / Heterocyclic Compounds with 4 or More Rings / Alkaloids / Ergot Alkaloids / Serotonin 5-HT1 Receptor Agonists / Ergotamines / Nervous System / Antimigraine Preparations / Alpha2 Agonists / P-glycoprotein/ABCB1 Inhibitors / Serotonin Modulators / Ergot Derivatives / Molecular Mechanisms of Pharmacological Action / Pharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / Cytochrome P-450 CYP3A Inhibitors / Cytochrome P-450 CYP3A4 Substrates / Combined Inhibitors of CYP3A4 and P-glycoprotein / Ergot alkaloids / Ergot alkaloids / Ergot alkaloidsFor use as therapy to abort or prevent vascular headache, e.g., migraine, migraine variants, or so called "histaminic cephalalgia".
DB00189
113-18-8
Ethchlorvynol144.599

C7H9ClO
ThumbPharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / Physiological Effects of Drugs / Central Nervous System Agents / Alcohols / Central Nervous System Depressants / Hypnotics and Sedatives / Chlorohydrins / Nervous System / Psycholeptics / Organic Chemicals / Other hypnotics and sedativesUsed for short-term hypnotic therapy in the management of insomnia for periods of up to one week in duration; however, this medication generally ha...
DB00353
113-42-8
Methylergometrine339.4314

C20H25N3O2
ThumbPharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / Physiological Effects of Drugs / Reproductive Control Agents / Oxytocics / Heterocyclic Compounds / Heterocyclic Compounds with 4 or More Rings / Alkaloids / Ergolines / Ergot Alkaloids / Ergonovine / Cytochrome P-450 CYP3A Inhibitors / Genito Urinary System and Sex Hormones / Uterotonics / Combined Inhibitors of CYP3A4 and P-glycoprotein / Ergot alkaloids and oxytocin incl. analogues, in combination / Ergot alkaloidsFor the prevention and control of excessive bleeding following vaginal childbirth
DB00422
113-45-1
Methylphenidate233.3062

C14H19NO2
ThumbPhenylacetates / Acids, Carbocyclic / Carboxylic Acids / Organic Chemicals / Piperidines / Heterocyclic Compounds, 1-Ring / Heterocyclic Compounds / Neurotransmitter Uptake Inhibitors / Membrane Transport Modulators / Molecular Mechanisms of Pharmacological Action / Pharmacologic Actions / Chemical Actions and Uses / Neurotransmitter Agents / Physiological Effects of Drugs / Dopamine Agents / Central Nervous System Agents / Therapeutic Uses / Dopamine Uptake Inhibitors / Central Nervous System Stimulants / Centrally Acting Sympathomimetics / Psychostimulants, Agents Used for Adhd and Nootropics / Psychoanaleptics / Nervous System / Cytochrome P-450 CYP2D6 Substrates / Cytochrome P-450 CYP2D6 Inhibitors / CYP2D6 Inhibitors (Weak) / Centrally acting sympathomimeticsFor use as an integral part of a total treatment program which typically includes other remedial measures (psychological, educational, social) for ...
DB09167
113-53-1
Dosulepin295.44

C19H21NS
ThumbMembrane Transport Modulators / Sulfur Compounds / Inorganic Chemicals / Neurotransmitter Uptake Inhibitors / Adrenergic Uptake Inhibitors / Thiepins / Dibenzothiepins / Adrenergic Agents / Neurotransmitter Agents / Heterocyclic Compounds, 1-Ring / Heterocyclic Compounds / Heterocyclic Compounds, 3-Ring / Antidepressive Agents / Psychotropic Drugs / Antidepressive Agents, Tricyclic / Nervous System / Psychoanaleptics / Non-Selective Monoamine Reuptake Inhibitors / Physiological Effects of Drugs / Central Nervous System Agents / Molecular Mechanisms of Pharmacological Action / Pharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / Organic Chemicals / Non-selective monoamine reuptake inhibitorsNot Annotated
DB01239
113-59-7
Chlorprothixene315.86

C18H18ClNS
ThumbThioxanthenes / Xanthenes / Heterocyclic Compounds, 3-Ring / Dopamine Agents / Neurotransmitter Agents / Tranquilizing Agents / Psychotropic Drugs / Dopamine Antagonists / Antipsychotic Agents / Thioxanthene Derivatives / Psycholeptics / P-glycoprotein/ABCB1 Inhibitors / Antipsychotic Agents (First Generation [Typical]) / Sulfur Compounds / Heterocyclic Compounds / Combined Inhibitors of CYP3A4 and P-glycoprotein / Central Nervous System Depressants / Physiological Effects of Drugs / Organic Chemicals / Inorganic Chemicals / Therapeutic Uses / Pharmacologic Actions / Chemical Actions and Uses / Molecular Mechanisms of Pharmacological Action / Central Nervous System Agents / Nervous System / Thioxanthene derivativesFor treatment of psychotic disorders (e.g. schizophrenia) and of acute mania occuring as part of bipolar disorders.
DB04840
1131-64-2
Debrisoquin175.2303

C10H13N3
ThumbIsoquinolines / Autonomic Agents / Cardiovascular Agents / Adrenergic Agents / Sympatholytics / Antihypertensive Agents / Guanidine Derivatives / Antiadrenergic Agents, Peripherally Acting / Cardiovascular System / P-glycoprotein/ABCB1 Substrates / Peripheral Nervous System Agents / Heterocyclic Compounds, 2-Ring / Heterocyclic Compounds / Cytochrome P-450 CYP2D6 Substrates / Molecular Mechanisms of Pharmacological Action / Neurotransmitter Agents / Physiological Effects of Drugs / Therapeutic Uses / Pharmacologic Actions / Chemical Actions and Uses / Guanidine derivativesFor the treatment of moderate and severe hypertension, either alone or as an adjunct, and for the treatment of renal hypertension.
DB09183
1132935-63-7
Dasabuvir493.58

C26H27N3O5S
ThumbAntiinfectives for Systemic Use / Direct Acting Antivirals / Antivirals for Systemic Use / Cytochrome P-450 CYP2D6 Substrates / Cytochrome P-450 CYP2C8 Substrates / Cytochrome P-450 CYP3A4 Substrates / BCRP/ABCG2 Inhibitors / Other antivirals / Other antiviralsDasabuvir, in combination with ombitasvir, paritaprevir, and ritonavir (as Viekira Pak) is indicated for the treatment of patients with genotype 1 ...
DB00181
1134-47-0
Baclofen213.661

C10H12ClNO2
ThumbAmino Acids, Peptides, and Proteins / Neurotransmitter Agents / Neuromuscular Agents / Amino Acids / Central Nervous System Depressants / gamma-Aminobutyric Acid / Aminobutyrates / GABA Agonists / GABA Agents / Muscle Relaxants, Central / GABA-B Receptor Agonists / Musculo-Skeletal System / Muscle Relaxants, Centrally Acting Agents / Muscle Relaxants / Central Nervous System Agents / Peripheral Nervous System Agents / Lipids / Carboxylic Acids / Fatty Acids / Acids, Acyclic / Butyrates / Fatty Acids, Volatile / Molecular Mechanisms of Pharmacological Action / Pharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / Physiological Effects of Drugs / Organic Chemicals / Other centrally acting agentsFor the alleviation of signs and symptoms of spasticity resulting from multiple sclerosis, particularly for the relief of flexor spasms and concomi...
DB00743
113662-23-0
Gadobenic acid667.73

C22H28GdN3O11
ThumbGadolinium / Specialty Uses of Chemicals / Diagnostic Uses of Chemicals / Contrast Media / Paramagnetic Contrast Media / Magnetic Resonance Imaging Contrast Media / Moderate Risk QTc-Prolonging Agents / Pharmacologic Actions / Chemical Actions and Uses / Paramagnetic contrast mediaGadobenate Dimeglumine is an MRI contrast agent used primarily for MR imaging of the liver. It can also be used for MRI of the heart, as well as an...
DB00758
113665-84-2
Clopidogrel321.822

C16H16ClNO2S
ThumbHematologic Agents / Purinergic P2 Receptor Antagonists / Purinergic Antagonists / Purinergic Agents / Platelet Aggregation Inhibitors / Purinergic P2Y Receptor Antagonists / Platelet Aggregation Inhibitors Excl. Heparin / Fibrinolytic Agents / Blood and Blood Forming Organs / Cytochrome P-450 CYP1A2 Substrates / Cytochrome P-450 CYP2B6 Inhibitors / Cytochrome P-450 CYP2C9 Inhibitors / Cytochrome P-450 CYP2C8 Inhibitors / P-glycoprotein/ABCB1 Substrates / Cytochrome P-450 CYP2B6 Inhibitors (moderate) / CYP2C8 Inhibitors (Strong) / Therapeutic Uses / Cytochrome P-450 CYP2B6 Substrates / Cytochrome P-450 CYP2C9 Substrates / Cytochrome P-450 CYP2C19 Substrates / Cytochrome P-450 CYP3A4 Substrates / Neurotransmitter Agents / Molecular Mechanisms of Pharmacological Action / Pharmacologic Actions / Chemical Actions and Uses / Physiological Effects of Drugs / Platelet aggregation inhibitors excl. heparinFor the reduction of atherosclerotic events (myocardial infarction, stroke, and vascular death) in patients with atherosclerosis documented by rece...
DB00633
113775-47-6
Dexmedetomidine200.2795

C13H16N2
ThumbAnalgesics, Non-Narcotic / Analgesics / Sensory System Agents / Azoles / Imidazoles / Cytochrome P-450 CYP1A2 Inhibitors / Hypnotics and Sedatives / Adrenergic alpha-Agonists / Adrenergic Agonists / Cytochrome P-450 CYP2D6 Inhibitors / Adrenergic alpha-2 Receptor Agonists / Psycholeptics / Alpha2 Agonists / Hypotensive Agents / Bradycardia-Causing Agents / Adrenergic Agents / Heterocyclic Compounds, 1-Ring / Heterocyclic Compounds / Cytochrome P-450 CYP2E1 Substrates / Central Nervous System Agents / Central Nervous System Depressants / Nervous System / Molecular Mechanisms of Pharmacological Action / Pharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / Physiological Effects of Drugs / Peripheral Nervous System Agents / Neurotransmitter Agents / Other hypnotics and sedativesFor sedation of initially intubated and mechanically ventilated patients during treatment in an intensive care setting, also used in pain relief; a...
Displaying drugs 176 - 200 of 2005 in total