Giardiasis

Also known as: Giardiasis [lambliasis] / Giardia infections / Lambliasis / Giardiasis (disorder) / Giardia lamblia infection / Infection by Giardia lamblia (disorder)

Drug	Drug Name	Drug Description
DB00643	Mebendazole	A benzimidazole anthelmintic used to treat helminth infections.
DB00916	Metronidazole	A nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections.
DB15759	Metronidazole benzoate	Not Annotated
DB13855	Nifuroxazide	An antibiotic indicated in the treatment of susceptible gastrointestinal infections.
DB13026	Ornidazole	A nitroimidazole agent indicated in the treatment of infections such as trichomoniasis, amebiasis, and giardiasis.
DB00911	Tinidazole	A nitroimidazole used to treat trichomoniasis, giardiasis, amebiasis, and bacterial vaginosis.

Drug	Drug Name	Target	Type
DB00643	Mebendazole	Tubulin alpha-1A chain	target
DB00643	Mebendazole	Tubulin beta-4B chain	target
DB00643	Mebendazole	Cytochrome P450 1A1	enzyme
DB00643	Mebendazole	Cytochrome P450 3A Subfamily	enzyme
DB00916	Metronidazole	Oxygen-insensitive NADPH nitroreductase	target
DB00916	Metronidazole	Cytochrome P450 2C9	enzyme
DB00916	Metronidazole	Cytochrome P450 3A4	enzyme
DB00916	Metronidazole	Cytochrome P450 2C8	enzyme
DB00916	Metronidazole	UDP-glucuronosyltransferase 1-1	enzyme
DB00916	Metronidazole	Anaerobic bacterial DNA	target
DB00916	Metronidazole	Protozoal DNA	target
DB00916	Metronidazole	P-glycoprotein 1	transporter
DB00916	Metronidazole	Cytochrome P450 2A6	enzyme
DB00916	Metronidazole	Cytochrome P450 3A5	enzyme
DB00916	Metronidazole	Cytochrome P450 3A7	enzyme
DB00911	Tinidazole	Cytochrome P450 3A4	enzyme
DB00911	Tinidazole	DNA	target
DB00911	Tinidazole	Bile salt export pump	transporter

Drug	Drug Name	Phase	Status	Count
DB00995	Auranofin	2	Completed	1
DB00916	Metronidazole	4	Terminated	1
DB00911	Tinidazole	4	Terminated	1
DB00518	Albendazole	Not Available	Completed	1
DB12834	Secnidazole	Not Available	Completed	1