Familial Mediterranean Fever
Also known as: Familial Mediterranean Syndrome / Familial Mediterranean Fever (FMF) / Familial Mediterranean Fever (FMF ) / Periodic fever syndromes / Familial Mediterranean fever (disorder) / Familial recurrent polyserositis
| Drug | Drug Name | Drug Description |
|---|---|---|
| DB06168 | Canakinumab | An interleukin-1β blocker used to treat Periodic Fever Syndromes such as Cryopyrin-Associated Periodic Syndromes (CAPS) and Familial Mediterranean Fever (FMF), and also to treat active Systemic Juvenile Idiopathic Arthritis (SJIA). |
| DB01394 | Colchicine | An alkaloid used to treat gout and Familial Mediterranean Fever as well as prevent major cardiovascular events. |
| Drug | Drug Name | Target | Type |
|---|---|---|---|
| DB06168 | Canakinumab | Interleukin-1 beta | target |
| DB01394 | Colchicine | Tubulin beta chain | target |
| DB01394 | Colchicine | Cytochrome P450 3A4 | enzyme |
| DB01394 | Colchicine | P-glycoprotein 1 | transporter |
| DB01394 | Colchicine | Cytochrome P450 2B6 | enzyme |
| DB01394 | Colchicine | Cytochrome P450 2C8 | enzyme |
| DB01394 | Colchicine | Cytochrome P450 2E1 | enzyme |
| DB01394 | Colchicine | Serum albumin | carrier |
| Drug | Drug Name | Phase | Status | Count |
|---|---|---|---|---|
| DB01394 | Colchicine | 1 | Completed | 1 |
| DB06168 | Canakinumab | 2 | Completed | 1 |
| DB16396 | Goflikicept | 2 | Recruiting | 2 |
| DB06372 | Rilonacept | 2 | Completed | 2 |
| DB06273 | Tocilizumab | 2 | Completed | 1 |
| DB06405 | Eprodisate | 2 / 3 | Completed | 1 |
| DB00026 | Anakinra | 3 | Completed | 1 |
| DB01394 | Colchicine | 4 | Completed | 1 |