Angioedema

Also known as: Angioedema reactions / Angio edema / Angioedemas / Angioneurotic edema / Angioedema (morphologic abnormality) / Angioneurotic oedema / Oedema angioneurotic / Quincke's edema / Angioedema (disorder) / Edema angioneurotic / Angioedema and urticaria / Angio-edema / Oedema Quincke's / Quincke's oedema / Giant urticaria / Edema Quincke's / Urticaria giant / Giant urticaria (disorder) / Giant hives / Hives giant

Drug	Drug Name	Drug Description
DB00748	Carbinoxamine	A first generation antihistamine used to treat allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, allergic reactions, and mild allergic reactions.
DB00283	Clemastine	An antihistamine with sedative and anticholinergic effects used to treat the symptoms of allergic rhinitis.
DB09555	Dexchlorpheniramine maleate	A first generation antihistamine used to treat allergic and vasomotor rhinitis, allergic conjunctivitis, and mild urticaria and angioedema.
DB01075	Diphenhydramine	A H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes.
DB01620	Pheniramine	An antihistamine used to treat allergic rhinitis and pruritus.

Drug	Drug Name	Target	Type
DB00748	Carbinoxamine	Histamine H1 receptor	target
DB00748	Carbinoxamine	alpha1-acid glycoprotein	carrier
DB00283	Clemastine	Histamine H1 receptor	target
DB00283	Clemastine	Cytochrome P450 2D6	enzyme
DB09555	Dexchlorpheniramine maleate	Cytochrome P450 2D6	enzyme
DB09555	Dexchlorpheniramine maleate	Histamine H1 receptor	target
DB09555	Dexchlorpheniramine maleate	Solute carrier family 22 member 1	carrier
DB09555	Dexchlorpheniramine maleate	Solute carrier family 22 member 2	carrier
DB09555	Dexchlorpheniramine maleate	Cytochrome P450 3A4	enzyme
DB01075	Diphenhydramine	Histamine H1 receptor	target
DB01075	Diphenhydramine	Cytochrome P450 2D6	enzyme
DB01075	Diphenhydramine	Cytochrome P450 2C9	enzyme
DB01075	Diphenhydramine	Cytochrome P450 2C19	enzyme
DB01075	Diphenhydramine	Solute carrier family 22 member 2	transporter
DB01075	Diphenhydramine	Solute carrier family 22 member 5	transporter
DB01075	Diphenhydramine	Prostaglandin G/H synthase 1	enzyme
DB01075	Diphenhydramine	Muscarinic acetylcholine receptor M2	target
DB01620	Pheniramine	Histamine H1 receptor	target
DB01620	Pheniramine	Nuclear receptor subfamily 1 group I member 3	target
DB01620	Pheniramine	Histamine H4 receptor	target

Drug	Drug Name	Phase	Status	Count
DB12126	Bradykinin	2	Unknown Status	1
DB14681	Cortisone	2	Completed	1
DB05311	Ecallantide	2	Unknown Status	1
DB00668	Epinephrine	2	Completed	1
DB06196	Icatibant	2	Completed	1
DB06612	Mepolizumab	2	Terminated	1
DB00043	Omalizumab	2	Completed	1
DB06404	Human C1-esterase inhibitor	2 / 3	Completed	1
DB06404	Human C1-esterase inhibitor	3	Completed	1
DB06196	Icatibant	3	Completed	1
DB16956	L-Acetylleucine	3	Completed	1
DB14597	Lanadelumab	3	Completed	2
DB00043	Omalizumab	3	Completed	1
DB00169	Cholecalciferol	Not Available	Completed	1
DB01109	Heparin	Not Available	Completed	1
DB14597	Lanadelumab	Not Available	No Longer Available	1