Vitamin B6 Deficiency

Also known as: Vitamin B 6 Deficiency / Pyridoxine deficiency / Vitamin B6 deficiency (disorder)

Drugs
Drugs and Targets

Drug	Drug Name	Drug Description
DB01987	Cocarboxylase	The coenzyme form of Vitamin B1 present in many animal tissues. It is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex.
DB00115	Cyanocobalamin	A vitamin available in many formulations to correct vitamin B12 deficiency.
DB08966	Fursultiamine	Compound used for therapy of thiamine deficiency. It has also been suggested for several non-deficiency disorders but has not yet proven useful. Fursultiamine is a vitamin B1 derivative.
DB00114	Pyridoxal phosphate	A vitamin available in many formulations to correct vitamin B6 deficiency.
DB00165	Pyridoxine	A vitamin used to correct vitamin B6 deficiency and to treat nausea during pregnancy.

Drug	Drug Name	Target	Type
DB01987	Cocarboxylase	Acetolactate synthase, catabolic	target
DB01987	Cocarboxylase	Pyruvate dehydrogenase E1 component	target
DB01987	Cocarboxylase	Pyruvate-flavodoxin oxidoreductase	target
DB01987	Cocarboxylase	Indole-3-pyruvate decarboxylase	target
DB01987	Cocarboxylase	Carboxyethylarginine synthase	target
DB01987	Cocarboxylase	Transketolase 1	target
DB01987	Cocarboxylase	RNA	target
DB01987	Cocarboxylase	Benzoylformate decarboxylase	enzyme
DB01987	Cocarboxylase	Pyruvate oxidase	enzyme
DB00115	Cyanocobalamin	Methionine synthase reductase	target
DB00115	Cyanocobalamin	Methylmalonic aciduria type A protein, mitochondrial	target
DB00115	Cyanocobalamin	Methylmalonyl-CoA mutase, mitochondrial	target
DB00115	Cyanocobalamin	Methylmalonic aciduria and homocystinuria type C protein	target
DB00115	Cyanocobalamin	Methionine synthase	target
DB00115	Cyanocobalamin	Methylenetetrahydrofolate reductase	target
DB00115	Cyanocobalamin	Protein amnionless	transporter
DB00115	Cyanocobalamin	Transcobalamin-1	transporter
DB00115	Cyanocobalamin	Transcobalamin-2	transporter
DB00115	Cyanocobalamin	Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial	enzyme
DB00115	Cyanocobalamin	Gastric intrinsic factor	transporter
DB00115	Cyanocobalamin	Cubilin	transporter
DB00115	Cyanocobalamin	Bifunctional adenosylcobalamin biosynthesis protein CobU	enzyme
DB00115	Cyanocobalamin	Low-density lipoprotein receptor-related protein 2	transporter
DB00115	Cyanocobalamin	Multidrug resistance-associated protein 1	transporter
DB00115	Cyanocobalamin	Pancreatic proteases	enzyme
DB00114	Pyridoxal phosphate	Cystathionine beta-synthase	target
DB00114	Pyridoxal phosphate	Alanine--glyoxylate aminotransferase 2, mitochondrial	target
DB00114	Pyridoxal phosphate	Glutamate decarboxylase 1	target
DB00114	Pyridoxal phosphate	Kynureninase	target
DB00114	Pyridoxal phosphate	Serine hydroxymethyltransferase, cytosolic	target
DB00114	Pyridoxal phosphate	Cysteine desulfurase, mitochondrial	target
DB00114	Pyridoxal phosphate	Aspartate aminotransferase, cytoplasmic	target
DB00114	Pyridoxal phosphate	Ornithine aminotransferase, mitochondrial	target
DB00114	Pyridoxal phosphate	Ornithine decarboxylase	target
DB00114	Pyridoxal phosphate	Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial	target
DB00114	Pyridoxal phosphate	4-aminobutyrate aminotransferase, mitochondrial	target
DB00114	Pyridoxal phosphate	Pyridoxine-5'-phosphate oxidase	target
DB00114	Pyridoxal phosphate	Sphingosine-1-phosphate lyase 1	target
DB00114	Pyridoxal phosphate	Tyrosine aminotransferase	target
DB00114	Pyridoxal phosphate	Kynurenine--oxoglutarate transaminase 1	target
DB00114	Pyridoxal phosphate	Glycogen phosphorylase, liver form	target
DB00114	Pyridoxal phosphate	Serine palmitoyltransferase 2	target
DB00114	Pyridoxal phosphate	Cysteine sulfinic acid decarboxylase	target
DB00114	Pyridoxal phosphate	Histidine decarboxylase	target
DB00114	Pyridoxal phosphate	Arginine decarboxylase	target
DB00114	Pyridoxal phosphate	L-serine dehydratase/L-threonine deaminase	target
DB00114	Pyridoxal phosphate	2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial	target
DB00114	Pyridoxal phosphate	Glycine dehydrogenase [decarboxylating], mitochondrial	target
DB00114	Pyridoxal phosphate	Alanine aminotransferase 1	target
DB00114	Pyridoxal phosphate	Phosphoserine aminotransferase	target
DB00114	Pyridoxal phosphate	5-aminolevulinate synthase, nonspecific, mitochondrial	target
DB00114	Pyridoxal phosphate	Serine--pyruvate aminotransferase	target
DB00114	Pyridoxal phosphate	Pyridoxal phosphate phosphatase	target
DB00114	Pyridoxal phosphate	Serine palmitoyltransferase 1	target
DB00114	Pyridoxal phosphate	Cystathionine gamma-lyase	target
DB00114	Pyridoxal phosphate	Branched-chain-amino-acid aminotransferase, cytosolic	target
DB00114	Pyridoxal phosphate	Branched-chain-amino-acid aminotransferase, mitochondrial	target
DB00114	Pyridoxal phosphate	Proline synthase co-transcribed bacterial homolog protein	target
DB00114	Pyridoxal phosphate	Aspartate aminotransferase, mitochondrial	target
DB00114	Pyridoxal phosphate	Glycogen phosphorylase, brain form	target
DB00114	Pyridoxal phosphate	Glycogen phosphorylase, muscle form	target
DB00114	Pyridoxal phosphate	Aromatic-L-amino-acid decarboxylase	target
DB00114	Pyridoxal phosphate	Serine hydroxymethyltransferase	target
DB00114	Pyridoxal phosphate	Glutamate decarboxylase 2	target
DB00114	Pyridoxal phosphate	Kynurenine--oxoglutarate transaminase 3	target
DB00114	Pyridoxal phosphate	Glutamate decarboxylase-like protein 1	target
DB00114	Pyridoxal phosphate	Selenocysteine lyase	target
DB00114	Pyridoxal phosphate	Immunoglobulin superfamily member 10	target
DB00114	Pyridoxal phosphate	5-phosphohydroxy-L-lysine phospho-lyase	target
DB00114	Pyridoxal phosphate	Serine hydroxymethyltransferase, mitochondrial	target
DB00114	Pyridoxal phosphate	5-aminolevulinate synthase, erythroid-specific, mitochondrial	target
DB00114	Pyridoxal phosphate	Alanine aminotransferase 2	target
DB00114	Pyridoxal phosphate	Molybdenum cofactor sulfurase	target
DB00114	Pyridoxal phosphate	Serine dehydratase-like	target
DB00114	Pyridoxal phosphate	Serine racemase	target
DB00114	Pyridoxal phosphate	O-phosphoseryl-tRNA(Sec) selenium transferase	target
DB00114	Pyridoxal phosphate	Serine palmitoyltransferase 3	target
DB00114	Pyridoxal phosphate	Glutamic acid decarboxylase	target
DB00114	Pyridoxal phosphate	Aspartate aminotransferase	target
DB00165	Pyridoxine	Pyridoxal kinase	target
DB00165	Pyridoxine	Cytochrome P450 1A1	enzyme
DB00165	Pyridoxine	Serum albumin	carrier
DB00165	Pyridoxine	Pyridoxal kinase	enzyme
DB00165	Pyridoxine	Pyridoxal phosphate phosphatase	enzyme
DB00165	Pyridoxine	Alkaline phosphatase, tissue-nonspecific isozyme	transporter
DB00165	Pyridoxine	Alkaline phosphatase, tissue-nonspecific isozyme	enzyme

Drug	Drug Name	Phase	Status	Count