Seasonal Affective Disorder

Also known as: Seasonal Affective Disorder (SAD) / Seasonal Affective Disorders / Seasonal affective disorder (disorder) / Seasonal depression

Drug	Drug Name	Drug Description
DB01156	Bupropion	A norepinephrine and dopamine reuptake inhibitor used in the treatment of major depressive disorder (MDD), seasonal affective disorder (SAD), and as an aid to smoking cessation.
DB01323	St. John's Wort	An herbal ingredient used in non-prescription therapeutic products for the short-term treatment of minor skin irritations, insomnia, depression, and anxiety.

Drug	Drug Name	Target	Type
DB01156	Bupropion	Sodium-dependent dopamine transporter	target
DB01156	Bupropion	Sodium-dependent noradrenaline transporter	target
DB01156	Bupropion	Cytochrome P450 2B6	enzyme
DB01156	Bupropion	Cytochrome P450 2D6	enzyme
DB01156	Bupropion	Alpha-1-acid glycoprotein 1	carrier
DB01156	Bupropion	Neuronal acetylcholine receptor subunit alpha-3	target
DB01156	Bupropion	Cytochrome P450 2C9	enzyme
DB01156	Bupropion	Cytochrome P450 2E1	enzyme
DB01156	Bupropion	Solute carrier family 22 member 2	transporter
DB01156	Bupropion	5-hydroxytryptamine receptor 3A	target
DB01323	St. John's Wort	P-glycoprotein 1	transporter
DB01323	St. John's Wort	Cytochrome P450 3A4	enzyme
DB01323	St. John's Wort	Cytochrome P450 2D6	enzyme
DB01323	St. John's Wort	Cytochrome P450 2C19	enzyme

Drug	Drug Name	Phase	Status	Count
DB00571	Propranolol	2	Completed	1
DB01156	Bupropion	3	Completed	1
DB00980	Ramelteon	4	Completed	1