Severe Rheumatoid arthritis

Drug	Drug Name	Drug Description
DB08904	Certolizumab pegol	A tumor necrosis factor (TNF) blocker used to treat a variety of autoimmune and autoinflammatory conditions like Crohn's disease, rheumatoid arthritis, active psoriatic arthritis, ankylosing spondylitis, axial spondyloarthritis, and plaque psoriasis.
DB00859	Penicillamine	A chelator used to treat Wilson's disease, cystinuria, and rheumatoid arthritis.
DB08895	Tofacitinib	A Janus kinase (JAK) inhibitor used to treat rheumatic conditions, such as rheumatoid arthritis and ankylosing spondylitis, and ulcerative colitis.

Drug	Drug Name	Target	Type
DB08904	Certolizumab pegol	Tumor necrosis factor	target
DB08904	Certolizumab pegol	Alcohol dehydrogenase [NADP(+)]	enzyme
DB00859	Penicillamine	Solute carrier organic anion transporter family member 1B1	transporter
DB00859	Penicillamine	Copper	target
DB08895	Tofacitinib	Non-receptor tyrosine-protein kinase TYK2	target
DB08895	Tofacitinib	Cytochrome P450 3A4	enzyme
DB08895	Tofacitinib	Cytochrome P450 2C19	enzyme
DB08895	Tofacitinib	Tyrosine-protein kinase JAK2	target
DB08895	Tofacitinib	Tyrosine-protein kinase JAK1	target
DB08895	Tofacitinib	Tyrosine-protein kinase JAK3	target
DB08895	Tofacitinib	Serum albumin	carrier

Drug	Drug Name	Phase	Status	Count