Calcium Nephrolithiasis

Also known as: Lithiasis Renal / Renal lithiasis / Stone, Kidney / Renal Calculi / Stones, Kidney / Stone;Renal / Kidney Stone / Kidney Stones / Renal Calculus / Kidney Calculi / Renal Stone / Renal Stones / Nephrolithiasis / Kidney calculus / Kidney calculus (& [staghorn]) / Nephrolithiasis NOS / Nephrolithiasis NOS (disorder) / (Calculus of kidney) or (nephrolithiasis NOS) / Calculus renal NOS / Calculus of kidney / Urinary calculus (& [kidney &/or ureter]) / Calculus renal / Renal calculus NOS / Renal calculus NOS (disorder) / Urinary calculus (& [kidney &/or ureter) / Kidney stone (disorder) / Calculus kidney

Drugs
Drugs and Targets

Drug	Drug Name	Drug Description
DB00594	Amiloride	A pyrizine compound used to treat hypertension and congestive heart failure.
DB00310	Chlorthalidone	A diuretic used to treat hypertension or edema caused by heart failure, renal failure, hepatic cirrhosis, estrogen therapy, and other conditions.
DB00999	Hydrochlorothiazide	A thiazide diuretic used to treat edema associated with a number of conditions, and hypertension.
DB09125	Potassium citrate	An agent used to manage renal tubular acidosis, hypocitraturic calcium oxalate nephrolithiasis, and uric acid lithiasis with or without calcium stones.
DB15574	beta-Pinene	A mono-terpene indicated in combination with other plant-derived compounds for the treatment of bladder, kidney, and urinary stones.

Drug	Drug Name	Target	Type
DB00594	Amiloride	Amiloride-sensitive sodium channel subunit beta	target
DB00594	Amiloride	Acid-sensing ion channel 1	target
DB00594	Amiloride	Amiloride-sensitive amine oxidase [copper-containing]	target
DB00594	Amiloride	Amiloride-sensitive sodium channel subunit alpha	target
DB00594	Amiloride	Amiloride-sensitive sodium channel subunit gamma	target
DB00594	Amiloride	Sodium/hydrogen exchanger 1	target
DB00594	Amiloride	Acid-sensing ion channel 2	target
DB00594	Amiloride	Amiloride-sensitive sodium channel subunit delta	target
DB00594	Amiloride	Urokinase-type plasminogen activator	target
DB00594	Amiloride	Solute carrier family 22 member 2	transporter
DB00594	Amiloride	Solute carrier family 22 member 4	transporter
DB00594	Amiloride	Amiloride-sensitive amine oxidase [copper-containing]	enzyme
DB00594	Amiloride	Amiloride-sensitive amine oxidase [copper-containing]	enzyme
DB00310	Chlorthalidone	Solute carrier family 12 member 1	target
DB00310	Chlorthalidone	Serum albumin	carrier
DB00310	Chlorthalidone	Carbonic anhydrase 1	target
DB00999	Hydrochlorothiazide	Solute carrier family 12 member 3	target
DB00999	Hydrochlorothiazide	Solute carrier family 22 member 6	transporter
DB00999	Hydrochlorothiazide	Calcium-activated potassium channel subunit alpha-1	target
DB00999	Hydrochlorothiazide	Serum albumin	carrier
DB00999	Hydrochlorothiazide	Solute carrier family 22 member 11	transporter
DB00999	Hydrochlorothiazide	Multidrug resistance-associated protein 4	transporter
DB00999	Hydrochlorothiazide	Solute carrier family 22 member 8	transporter

Drug	Drug Name	Phase	Status	Count