Refractory Acute Promyelocytic Leukemia

Drug	Drug Name	Drug Description
DB01169	Arsenic trioxide	A chemotherapeutic agent used in the treatment of refractory or relapsed acute promyelocytic leukemia in patients with prior retinoid and anthracycline chemotherapy.

Drug	Drug Name	Target	Type
DB01169	Arsenic trioxide	Inhibitor of nuclear factor kappa-B kinase subunit beta	target
DB01169	Arsenic trioxide	Transcription factor AP-1	target
DB01169	Arsenic trioxide	G1/S-specific cyclin-D1	target
DB01169	Arsenic trioxide	Mitogen-activated protein kinase 3	target
DB01169	Arsenic trioxide	Mitogen-activated protein kinase 1	target
DB01169	Arsenic trioxide	RAC-alpha serine/threonine-protein kinase	target
DB01169	Arsenic trioxide	Canalicular multispecific organic anion transporter 1	transporter
DB01169	Arsenic trioxide	Thioredoxin reductase 1, cytoplasmic	target
DB01169	Arsenic trioxide	P-glycoprotein 1	transporter
DB01169	Arsenic trioxide	Cytochrome P450 3A4	enzyme
DB01169	Arsenic trioxide	Cyclin-dependent kinase inhibitor 1	target
DB01169	Arsenic trioxide	Histone deacetylase 1	target
DB01169	Arsenic trioxide	Protein PML	target
DB01169	Arsenic trioxide	Serum albumin	carrier

Drug	Drug Name	Phase	Status	Count
DB01169	Arsenic trioxide	4	Unknown Status	1