Severe Migraine

Drug	Drug Name	Drug Description
DB04841	Flunarizine	A selective calcium-entry blocker used as migraine prophylaxis in patients with severe and frequent episodes who have not responded adequately to more common treatments.

Drug	Drug Name	Target	Type
DB04841	Flunarizine	Histamine H1 receptor	target
DB04841	Flunarizine	Voltage-dependent T-type calcium channel subunit alpha-1G	target
DB04841	Flunarizine	Voltage-dependent T-type calcium channel subunit alpha-1H	target
DB04841	Flunarizine	Voltage-dependent T-type calcium channel subunit alpha-1I	target
DB04841	Flunarizine	Calmodulin	target
DB04841	Flunarizine	Cytochrome P450 2D6	enzyme
DB04841	Flunarizine	Cytochrome P450 2C9	enzyme
DB04841	Flunarizine	Cytochrome P450 1A1	enzyme
DB04841	Flunarizine	Cytochrome P450 1A2	enzyme
DB04841	Flunarizine	Cytochrome P450 2A6	enzyme
DB04841	Flunarizine	Cytochrome P450 3A4	enzyme

Drug	Drug Name	Phase	Status	Count