Homozygous Sitosterolemia

Also known as: Homozygous sitosterolemia (disorder)

Drug	Drug Name	Drug Description
DB00973	Ezetimibe	A cholesterol absorption inhibitor used to lower total cholesterol, LDL-C, Apo-B, and non-HDL-C in primary hyperlipidemia and familial cholesterolemia.

Drug	Drug Name	Target	Type
DB00973	Ezetimibe	Niemann-Pick C1-like protein 1	target
DB00973	Ezetimibe	Aminopeptidase N	target
DB00973	Ezetimibe	Sterol O-acyltransferase 1	target
DB00973	Ezetimibe	UDP-glucuronosyltransferase 1-1	enzyme
DB00973	Ezetimibe	UDP-glucuronosyltransferase 1-3	enzyme
DB00973	Ezetimibe	P-glycoprotein 1	transporter
DB00973	Ezetimibe	Canalicular multispecific organic anion transporter 1	transporter
DB00973	Ezetimibe	Solute carrier organic anion transporter family member 1B1	transporter
DB00973	Ezetimibe	UDP-glucuronosyltransferase 2B15	enzyme
DB00973	Ezetimibe	UDP-glucuronosyltransferase 2B7	enzyme
DB00973	Ezetimibe	Cytochrome P450 3A4	enzyme
DB00973	Ezetimibe	Canalicular multispecific organic anion transporter 2	transporter
DB00973	Ezetimibe	ATP-binding cassette sub-family G member 2	transporter
DB00973	Ezetimibe	Cytochrome P450 2C8	enzyme
DB00973	Ezetimibe	Bile salt export pump	transporter

Drug	Drug Name	Phase	Status	Count
DB00973	Ezetimibe	Not Available	Completed	2