Refractory partial onset seizure

Also known as: Refractory Partial Onset Seizures / Refractory Partial Seizures / Refractory Partial-Onset Seizures

Drug	Drug Name	Drug Description
DB04953	Ezogabine	An antiepileptic agent used as an adjuvant treatment of partial-onset seizures.
DB00949	Felbamate	An anticonvulsant used to treat severe epilepsy.

Drug	Drug Name	Target	Type
DB04953	Ezogabine	Potassium voltage-gated channel subfamily KQT member 2	target
DB04953	Ezogabine	Potassium voltage-gated channel subfamily KQT member 3	target
DB04953	Ezogabine	Potassium voltage-gated channel subfamily KQT member 4	target
DB04953	Ezogabine	Potassium voltage-gated channel subfamily KQT member 5	target
DB04953	Ezogabine	UDP-glucuronosyltransferase 1-1	enzyme
DB04953	Ezogabine	UDP-glucuronosyltransferase 1-3	enzyme
DB04953	Ezogabine	UDP-glucuronosyltransferase 1-4	enzyme
DB04953	Ezogabine	UDP-glucuronosyltransferase 1-9	enzyme
DB04953	Ezogabine	Arylamine N-acetyltransferase 2	enzyme
DB00949	Felbamate	Glutamate receptor ionotropic, NMDA 2B	target
DB00949	Felbamate	Glutamate receptor ionotropic, NMDA 2A	target
DB00949	Felbamate	Cytochrome P450 2C19	enzyme
DB00949	Felbamate	Cytochrome P450 3A4	enzyme
DB00949	Felbamate	Cytochrome P450 2E1	enzyme
DB00949	Felbamate	Cytochrome P450 2C9	enzyme

Drug	Drug Name	Phase	Status	Count
DB08883	Perampanel	2	Completed	2
DB08883	Perampanel	3	Completed	3
DB06201	Rufinamide	3	Terminated	1
DB06201	Rufinamide	3	Withdrawn	1