| ID |
4466 |
| Name |
Glutathione-independent formaldehyde dehydrogenase |
| Synonyms |
|
| Gene Name |
fdhA |
| Protein Sequence |
>Glutathione-independent formaldehyde dehydrogenase
MSGNRGVVYLGSGKVEVQKIDYPKMQDPRGKKIEHGVILKVVSTNICGSDQHMVRGRTTA
QVGLVLGHEITGEVIEKGRDVENLQIGDLVSVPFNVACGRCRSCKEMHTGVCLTVNPARA
GGAYGYVDMGDWTGGQAEYLLVPYADFNLLKLPDRDKAMEKIRDLTCLSDILPTGYHGAV
TAGVGPGSTVYVAGAGPVGLAAAASARLLGAAVVIVGDLNPARLAHAKAQGFEIADLSLD
TPLHEQIAALLGEPEVDCAVDAVGFEARGHGHEGAKHEAPATVLNSLMQVTRVAGKIGIP
GLYVTEDPGAVDAAAKIGSLSIRFGLGWAKSHSFHTGQTPVMKYNRALMQAIMWDRINIA
EVVGVQVISLDDAPRGYGEFDAGVPKKFVIDPHKTFSAA
|
| Number of Residues |
399 |
| Molecular Weight |
42083 |
| Theoretical pI |
6.70 |
| GO Classification |
| Function |
| binding |
| catalytic activity |
| oxidoreductase activity |
| ion binding |
| cation binding |
| transition metal ion binding |
| zinc ion binding |
|
| General Function |
Involved in zinc ion binding |
| Specific Function |
Catalyzes the oxidation of long-chain alcohols but is inactive against ethanol |
| Pathways |
Not Available |
| Reactions |
Not Available |
| Pfam Domain Function |
|
| Signals |
None |
| Transmembrane Regions |
None |
| Essentiality |
Non-Essential |
| GenBank Protein ID |
Not Available |
| UniProtKB ID |
P46154  |
| UniProtKB Entry Name |
FADH_PSEPU |
| PDB ID |
1KOL |
| PDB File |
show |
| 3D Structure |
View 3D Structure |
| Cellular Location |
Not Available |
| Gene Sequence |
>1200 bp
ATGTCTGGTAATCGTGGTGTCGTTTATCTCGGTTCGGGCAAGGTCGAAGTCCAGAAGATC
GACTACCCCAAAATGCAGGACCCTCGCGGCAAGAAGATCGAGCACGGGGTCATCCTGAAA
GTCGTCTCCACCAACATCTGCGGCTCGGACCAGCACATGGTGCGCGGTCGTACCACCGCC
CAGGTAGGCCTCGTGCTTGGCCACGAGATCACCGGTGAGGTGATCGAGAAGGGCCGTGAC
GTAGAGAACCTGCAGATCGGCGACCTGGTTTCCGTACCCTTCAACGTGGCCTGCGGCCGC
TGCCGTTCCTGCAAGGAAATGCACACCGGCGTTTGCCTGACCGTCAATCCGGCCCGCGCT
GGCGGCGCCTACGGCTATGTCGACATGGGCGACTGGACCGGTGGCCAGGCCGAGTACTTG
CTGGTGCCCTACGCCGACTTCAACCTGCTCAAGCTGCCGGATCGCGACAAGGCCATGGAG
AAGATCCGTGACCTGACCTGCCTTTCCGACATCCTGCCCACCGGCTACCACGGCGCCGTA
ACTGCCGGCGTTGGCCCGGGCAGCACCGTGTACGTGGCCGGTGCCGGCCCGGTCGGCCTG
GCCGCTGCCGCCTCCGCTCGCCTGCTGGGCGCCGCCGTGGTTATCGTCGGCGACCTCAAC
CCCGCCCGACTGGCCCACGCCAAGGCGCAGGGCTTCGAGATCGCCGACCTGTCGCTGGAC
ACCCCGCTGCACGAGCAGATCGCTGCGCTGCTGGGAGAGCCGGAAGTGGATTGCGCGGTG
GATGCGGTGGGCTTCGAAGCTCGCGGCCACGGCCACGAAGGTGCCAAGCACGAAGCCCCG
GCCACTGTGCTGAACTCGCTCATGCAAGTCACCCGCGTGGCCGGCAAGATCGGTATCCCC
GGCCTTTACGTCACCGAAGATCCGGGTGCCGTGGACGCCGCGGCGAAGATCGGCAGCCTG
AGTATTCGCTTCGGCCTCGGCTGGGCGAAATCCCACAGCTTCCACACTGGCCAGACCCCG
GTGATGAAGTACAACCGCGCACTCATGCAAGCGATCATGTGGGACCGCATCAATATCGCC
GAAGTGGTGGGCGTGCAGGTCATCAGCCTGGACGACGCACCGCGTGGCTATGGCGAGTTC
GATGCCGGCGTGCCGAAGAAGTTCGTCATCGACCCGCACAAGACCTTCAGCGCGGCCTGA
|
| GenBank Gene ID |
D21201 |
| GeneCard ID |
Not Available |
| GenAtlas ID |
Not Available |
| HGNC ID |
Not Available |
| HPRD ID |
Not Available |
| IUPHAR ID |
Not Available |
| Guide to Pharmacology ID |
Not Available |
| Chromosome Location |
Not Available |
| Locus |
Not Available |
| SNPs |
fdhA |
| General References |
- Ito K, Takahashi M, Yoshimoto T, Tsuru D: Cloning and high-level expression of the glutathione-independent formaldehyde dehydrogenase gene from Pseudomonas putida. J Bacteriol. 1994 May;176(9):2483-91. Pubmed
|
| Drugs |
| # |
DrugBank ID |
Drug Name |
Drug Type |
Drug Groups |
| 1 |
DB01907 |
Nicotinamide-Adenine-Dinucleotide |
small molecule |
experimental |
|
