| ID |
4818 |
| Name |
Beta-lactamase CTX-M-27 |
| Synonyms |
Not Available |
| Gene Name |
blaCTX-M-27 |
| Protein Sequence |
>Beta-lactamase CTX-M-27
MVTKRVQRMMFAAAACIPLLLGSAPLYAQTSAVQQKLAALEKSSGGRLGVALIDTADNTQ
VLYRGDERFPMCSTSKVMAAAAVLKQSETQKQLLNQPVEIKPADLVNYNPIAEKHVNGTM
TLAELSAAALQYSDNTAMNKLIAQLGGPGGVTAFARAIGDETFRLDRTEPTLNTAIPGDP
RDTTTPRAMAQTLRQLTLGHALGETQRAQLVTWLKGNTTGAASIRAGLPTSWTVGDKTGS
GGYGTTNDIAVIWPQGRAPLVLVTYFTQPQQNAESRRDVLASAARIIAEGL
|
| Number of Residues |
291 |
| Molecular Weight |
30922 |
| Theoretical pI |
9.63 |
| GO Classification |
| Function |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides |
| beta-lactamase activity |
| catalytic activity |
| hydrolase activity |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| Process |
| response to chemical stimulus |
| response to drug |
| response to antibiotic |
| physiological process |
| drug metabolism |
| antibiotic metabolism |
| metabolism |
| antibiotic catabolism |
| cellular metabolism |
| beta-lactam antibiotic catabolism |
| response to stimulus |
| response to abiotic stimulus |
|
| General Function |
Involved in beta-lactamase activity |
| Specific Function |
Not Available |
| Pathways |
Not Available |
| Reactions |
Not Available |
| Pfam Domain Function |
|
| Signals |
None |
| Transmembrane Regions |
None |
| Essentiality |
Non-Essential |
| GenBank Protein ID |
Not Available |
| UniProtKB ID |
Q840M4  |
| UniProtKB Entry Name |
Q840M4_ECOLX |
| PDB ID |
1YLW |
| PDB File |
show |
| 3D Structure |
View 3D Structure |
| Cellular Location |
Cytoplasmic |
| Gene Sequence |
>876 bp
ATGGTGACAAAGAGAGTGCAACGGATGATGTTCGCGGCGGCGGCGTGCATTCCGCTGCTG
CTGGGCAGCGCGCCGCTTTATGCGCAGACGAGTGCGGTGCAGCAAAAGCTGGCGGCGCTG
GAGAAAAGCAGCGGAGGGCGGCTGGGCGTCGCGCTCATCGATACCGCAGATAATACGCAG
GTGCTTTATCGCGGTGATGAACGCTTTCCAATGTGCAGTACCAGTAAAGTTATGGCGGCC
GCGGCGGTGCTTAAGCAGAGTGAAACGCAAAAGCAGCTGCTTAATCAGCCTGTCGAGATC
AAGCCTGCCGATCTGGTTAACTACAATCCGATTGCCGAAAAACACGTCAACGGCACAATG
ACGCTGGCAGAACTGAGCGCGGCCGCGTTGCAGTACAGCGACAATACCGCCATGAACAAA
TTGATTGCCCAGCTCGGTGGCCCGGGAGGCGTGACGGCTTTTGCCCGCGCGATCGGCGAT
GAGACGTTTCGTCTGGATCGCACTGAACCTACGCTGAATACCGCCATTCCCGGCGACCCG
AGAGACACCACCACGCCGCGGGCGATGGCGCAGACGTTGCGTCAGCTTACGCTGGGTCAT
GCGCTGGGCGAAACCCAGCGGGCGCAGTTGGTGACGTGGCTCAAAGGCAATACGACCGGC
GCAGCCAGCATTCGGGCCGGCTTACCGACGTCGTGGACTGTGGGTGATAAGACCGGCAGC
GGCGGCTACGGCACCACCAATGATATTGCGGTGATCTGGCCGCAGGGTCGTGCGCCGCTG
GTTCTGGTGACCTATTTTACCCAGCCGCAACAGAACGCAGAGAGCCGCCGCGATGTGCTG
GCTTCAGCGGCGAGAATCATCGCCGAAGGGCTGTAA
|
| GenBank Gene ID |
AY156923 |
| GeneCard ID |
Not Available |
| GenAtlas ID |
Not Available |
| HGNC ID |
Not Available |
| HPRD ID |
Not Available |
| IUPHAR ID |
Not Available |
| Guide to Pharmacology ID |
Not Available |
| Chromosome Location |
Not Available |
| Locus |
Not Available |
| SNPs |
blaCTX-M-27 |
| General References |
- Bonnet R, Recule C, Baraduc R, Chanal C, Sirot D, De Champs C, Sirot J: Effect of D240G substitution in a novel ESBL CTX-M-27. J Antimicrob Chemother. 2003 Jul;52(1):29-35. Epub 2003 May 29. Pubmed
|
| Drugs |
| # |
DrugBank ID |
Drug Name |
Drug Type |
Drug Groups |
| 1 |
DB02772 |
Sucrose |
small molecule |
experimental |
|
