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DNA

ID 874
Name DNA
Synonyms
  • Deoxyribonucleic acid
Gene Name Not Available
Protein Sequence Not Available
Molecular Weight 7656 (double strand)
Theoretical pI Not Available
GO Classification
Biological Process
DNA replication and chromosomal cycle
DNA replication
DNA-dependent DNA replication
DNA replication, synthesis of RNA primer
transcription
transcription, DNA dependent
Cellular Component
nucleus
mitochondria
cell
intracellular
Function
information storage
information transfer
General Function Biological information storage and information transfer
Specific Function DNA is the molecule of heredity, as it is responsible for the genetic propagation of most inherited traits. It is a polynucleic acid that carries genetic information on cell growth, division, and function. DNA consists of two long strands of nucleotides twisted into a double helix and held together by hydrogen bonds. The sequence of nucleotides determines hereditary characteristics. Each strand serves as the template for subsequent DNA replication and as a template for mRNA production, leading to protein synthesis via ribosomes.
Pathways Not Available
Reactions
  • DNA + DNA polymerase + nNTP = 2 DNA + nNDP
  • DNA + RNA polymerase + NTP = mRNA + nNDP
Pfam Domain Function Not Available
Signals None
Transmembrane Regions None
Essentiality Non-Essential
GenBank Protein ID Not Available
UniProtKB ID Not Available
UniProtKB Entry Name Not Available
PDB ID 1BNA Link_out
PDB File show
3D Structure View 3D Structure
Cellular Location Nucleus and mitochondria
Gene Sequence 
>Example: Dickerson dodecamer
CGCGAATTCGCG
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
HPRD ID Not Available
IUPHAR ID Not Available
Guide to Pharmacology ID Not Available
Chromosome Location Not Available
Locus All loci
SNPs Not Available
General References
  1. Nadeau D, Marchand C: Change in the kinetics of sulphacetamide tissue distribution in Walker tumor-bearing rats. Drug Metab Dispos. 1975 Nov-Dec;3(6):565-76. Pubmed
Drugs
# DrugBank ID Drug Name Drug Type Drug Groups
1 DB01702 2-(3,4-Dihydroxyphenyl)Acetic Acid small molecule experimental
2 DB00173 Adenine small molecule approved, nutraceutical
3 DB00131 Adenosine monophosphate small molecule approved, nutraceutical
4 DB00488 Altretamine small molecule approved
5 DB00276 Amsacrine small molecule approved
6 DB00928 Azacitidine small molecule approved, investigational
7 DB02379 Beta-D-Glucose small molecule experimental
8 DB00290 Bleomycin small molecule approved
9 DB01008 Busulfan small molecule approved, investigational
10 DB01101 Capecitabine small molecule approved, investigational
11 DB00958 Carboplatin small molecule approved
12 DB00262 Carmustine small molecule approved
13 DB00291 Chlorambucil small molecule approved
14 DB00827 Cinoxacin small molecule approved
15 DB00515 Cisplatin small molecule approved
16 DB00242 Cladribine small molecule approved, investigational
17 DB00631 Clofarabine small molecule approved, investigational
18 DB00845 Clofazimine small molecule approved
19 DB00531 Cyclophosphamide small molecule approved, investigational
20 DB00987 Cytarabine small molecule approved, investigational
21 DB00851 Dacarbazine small molecule approved
22 DB00970 Dactinomycin small molecule approved
23 DB00694 Daunorubicin small molecule approved
24 DB01262 Decitabine small molecule approved, investigational
25 DB00003 Dornase Alfa biotech approved
26 DB00997 Doxorubicin small molecule approved, investigational
27 DB00442 Entecavir small molecule approved, investigational
28 DB00445 Epirubicin small molecule approved
29 DB01099 Flucytosine small molecule approved
30 DB01073 Fludarabine small molecule approved
31 DB00693 Fluorescein small molecule approved
32 DB00544 Fluorouracil small molecule approved
33 DB00614 Furazolidone small molecule approved
34 DB01004 Ganciclovir small molecule approved, investigational
35 DB00441 Gemcitabine small molecule approved
36 DB00406 Gentian Violet small molecule approved
37 DB00536 Guanidine small molecule approved
38 DB01611 Hydroxychloroquine small molecule approved
39 DB01040 Hydroxystilbamidine Isethionate small molecule approved
40 DB01177 Idarubicin small molecule approved
41 DB00249 Idoxuridine small molecule approved
42 DB01181 Ifosfamide small molecule approved
43 DB00709 Lamivudine small molecule approved, investigational
44 DB01913 Lipid Fragment small molecule experimental
45 DB01206 Lomustine small molecule approved
46 DB04967 Lucanthone small molecule approved, investigational
47 DB00888 Mechlorethamine small molecule approved
48 DB01042 Melphalan small molecule approved
49 DB00553 Methoxsalen small molecule approved
50 DB00916 Metronidazole small molecule approved
51 DB00305 Mitomycin small molecule approved
52 DB01204 Mitoxantrone small molecule approved, investigational
53 DB00779 Nalidixic Acid small molecule approved
54 DB01280 Nelarabine small molecule approved, investigational
55 DB06803 Niclosamide small molecule approved
56 DB00526 Oxaliplatin small molecule approved, investigational
57 DB01096 Oxamniquine small molecule approved
58 DB00738 Pentamidine small molecule approved
59 DB03148 Phosphomethylphosphonic Acid Adenosyl Ester small molecule experimental
60 DB00236 Pipobroman small molecule approved
61 DB06810 Plicamycin small molecule approved, withdrawn
62 DB01168 Procarbazine small molecule approved
63 DB01123 Proflavine small molecule approved
64 DB01103 Quinacrine small molecule approved
65 DB00811 Ribavirin small molecule approved
66 DB05245 Silver sulfadiazine small molecule approved
67 DB00127 Spermine small molecule approved, nutraceutical
68 DB00428 Streptozocin small molecule approved
69 DB01265 Telbivudine small molecule approved, investigational
70 DB00853 Temozolomide small molecule approved, investigational
71 DB00300 Tenofovir small molecule approved, investigational
72 DB01041 Thalidomide small molecule approved, withdrawn, investigational
73 DB01987 Thiamin Diphosphate small molecule experimental
74 DB00352 Thioguanine small molecule approved
75 DB04572 Thiotepa small molecule approved
76 DB00911 Tinidazole small molecule approved, investigational
77 DB01030 Topotecan small molecule approved, investigational
78 DB05109 Trabectedin small molecule approved, investigational
79 DB00432 Trifluridine small molecule approved
80 DB04571 Trioxsalen small molecule approved
81 DB00791 Uracil mustard small molecule approved
82 DB01610 Valganciclovir small molecule approved, investigational
83 DB00385 Valrubicin small molecule approved
84 DB00194 Vidarabine small molecule approved
85 DB00126 Vitamin C small molecule approved, nutraceutical