Association Browse

Displaying targets 3926 - 3950 of 4178 in total

Name	UniProt ID Gene Name	Species Category Species	Specific function
Nicotinamide phosphoribosyltransferase	P43490 NAMPT	human Homo sapiens	Catalyzes the condensation of nicotinamide with 5- phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway (By similarity)
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Q13627 DYRK1A	human Homo sapiens	May play a role in a signaling pathway regulating nuclear functions of cell proliferation. Phosphorylates serine, threonine and tyrosine residues in its sequence and in exogenous substrates
Crumbs-like protein 2	Q0QD46 CRB2	human Homo sapiens
Replicase polyprotein 1a	P0C6U8 1a	viral Betacoronavirus Human SARS coronavirus	Nsp9 is a ssRNA-binding protein. nsp7 and eight copies of nsp8 assemble to form a heterohexadecamer. Nsp9 is a dimer. Nsp10 forms a dodecamer
AppA protein	Q53119 appA	bacterial Rhodobacter sphaeroides
Sulfide-quinone reductase	O67931 sqr	bacterial Aquifex aeolicus
Sulfide-quinone reductase, putative	B7JBP8 AFE_1792	bacterial Acidithiobacillus ferrooxidans
Light-harvesting protein B-800/850 beta 1 chain	P95673 B1	bacterial Rhodospirillum molischianum	Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers
Light-harvesting protein B-800/850 alpha chain	P97253 A1	bacterial Rhodospirillum molischianum	Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase	P0AF14 mtnN	bacterial Escherichia coli O157:H7	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
Ribonuclease H	Q9KEI9 rnhA	bacterial Bacillus halodurans	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
STE20-like serine/threonine-protein kinase	Q9H2G2 SLK	human Homo sapiens	Mediates apoptosis and actin stress fiber dissolution (By similarity)
Calcium/calmodulin-dependent protein kinase type IV	Q16566 CAMK4	human Homo sapiens	Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. May be involved in transcriptional regulation. May be involved in regulation of microtubule dynamics. In vitro, phosphorylates CREB1, CREBBP, PRM2, MEF2A, MEF2D and STMN1/OP18. May be involved in spermatogenesis. May play a role in the consolidation/retention of hippocampus-dependent long-term memory (By similarity)
Dual specificity protein kinase CLK3	P49761 CLK3	human Homo sapiens	Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates serines, threonines and tyrosines
Fumarate reductase flavoprotein subunit	P17412 frdA	bacterial Wolinella succinogenes	The fumarate reductase enzyme complex is required for fumarate respiration using formate or sulfide as electron donor
Fumarate reductase iron-sulfur subunit	P17596 frdB	bacterial Wolinella succinogenes	The fumarate reductase enzyme complex is required for fumarate respiration using formate or sulfide as electron donor
Fumarate reductase cytochrome b subunit	P17413 frdC	bacterial Wolinella succinogenes	The fumarate reductase enzyme complex is required for fumarate respiration using formate or sulfide as electron donor
Poly [ADP-ribose] polymerase 3	Q9Y6F1 PARP3	human Homo sapiens	Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing
Lactaldehyde dehydrogenase	P25553 aldA	bacterial Escherichia coli	Acts on lactaldehyde as well as other aldehydes
Cytochrome c oxidase subunit 1	P33517 ctaD	bacterial Rhodobacter sphaeroides	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme a of subunit 1 to the bimetallic center formed by heme a3 and copper B. This cytochrome c oxidase shows proton pump activity across the membrane in addition to the electron transfer
Cytochrome c oxidase subunit 2	Q03736 ctaC	bacterial Rhodobacter sphaeroides	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
Nuclear receptor coactivator 5	Q9HCD5 NCOA5	human Homo sapiens	Nuclear receptor coregulator that can have both coactivator and corepressor functions. Interacts with nuclear receptors for steroids (ESR1 and ESR2) independently of the steroid binding domain (AF-2) of the ESR receptors, and with the orphan nuclear receptor NR1D2. Involved in the coactivation of nuclear steroid receptors (ER) as well as the corepression of MYC/c-myc in response to 17-beta-estradiol (E2)
Type I polyketide synthase PikAIV	Q9ZGI2 pikAIV	bacterial Streptomyces venezuelae
Putative cytochrome P450 130	Q11062 cyp130	bacterial Mycobacterium tuberculosis
Pol polyprotein	Q88016	viral Primate lentivirus group Simian immunodeficiency virus	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

Displaying targets 3926 - 3950 of 4178 in total