Association Browse
Displaying targets 3951 - 3975 of 4170 in total
| Name | UniProt ID Gene Name |
Species Category Species |
Specific function |
|---|---|---|---|
| RAC-beta serine/threonine-protein kinase | P31751  AKT2 |
human Homo sapiens |
General protein kinase capable of phosphorylating several known proteins |
| Platelet-activating factor acetylhydrolase | Q13093 PLA2G7 |
human Homo sapiens |
Modulates the action of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. Has a specificity for substrates with a short residue at the sn-2 position. It is inactive against long-chain phospholipids |
| Histone deacetylase 4 | P56524 HDAC4 |
human Homo sapiens |
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D |
| Phosducin | P20941 PDC |
human Homo sapiens |
May participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism |
| GTPase KRas | P01116 KRAS |
human Homo sapiens |
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity |
| Rab proteins geranylgeranyltransferase component A 1 | P24386 CHM |
human Homo sapiens |
Binds unprenylated Rab proteins, presents it to the catalytic Rab GGTase dimer, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane |
| Serine/threonine-protein kinase PCTAIRE-1 | Q00536 CDK16 |
human Homo sapiens |
May play a role in signal transduction cascades in terminally differentiated cells |
| Endo-1,4-beta-xylanase Z | P10478 xynZ |
bacterial Clostridium thermocellum |
Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans |
| Est1e | D2YW37 |
bacterial Clostridium proteoclasticum |
|
| Neocarzinostatin | P0A3R9 ncsA |
bacterial Streptomyces carzinostaticus |
NCS has antibiotic activity (for Gram-positive bacteria) and antitumor activity (for certain mouse tumors). NCS binds non- covalently to a chromophore which is the cytotoxic and mutagenic component of the antibiotic. The chromophore binds to DNA as a weak intercalator and causes single- and double-strand breaks |
| 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | Q8EBR3 ispF |
bacterial Shewanella oneidensis |
Converts 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MECDP) and CMP (By similarity) |
| Lantibiotic nisin-Z | P29559 nisZ |
bacterial Lactococcus lactis subsp. |
Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores |
| D-alanine--D-alanine ligase | Q5HEB7 ddl |
bacterial Staphylococcus aureus |
Cell wall formation (By similarity) |
| Dipeptidyl aminopeptidase IV, putative | Q7MUW6 ptpA |
bacterial Porphyromonas gingivalis |
|
| Arylacetamide deacetylase-like 2 | Q6P093 AADACL2 |
human Homo sapiens |
|
| Phenylalanyl-tRNA synthetase alpha chain | Q4L5E3 pheS |
bacterial Staphylococcus haemolyticus |
ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe) |
| Phenylalanyl-tRNA synthetase beta chain | Q4L5E4 pheT |
bacterial Staphylococcus haemolyticus |
ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe) |
| Botulinum neurotoxin type A | P10845 botA |
bacterial Clostridium botulinum |
|
| BoNT/A | Q7B8V4 bont/a |
bacterial Clostridium botulinum |
|
| Platelet-activating factor acetylhydrolase IB subunit gamma | Q15102 PAFAH1B3 |
human Homo sapiens |
Inactivates paf by removing the acetyl group at the sn-2 position. This is a catalytic subunit. Plays an important role during the development of brain |
| Calcium/calmodulin-dependent protein kinase type II subunit delta | Q13557 CAMK2D |
human Homo sapiens |
|
| Serine/threonine-protein kinase MST4 | Q9P289 MST4 |
human Homo sapiens |
Potential mediator of cell growth. Pro-apoptotic |
| UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase | P47205 lpxC |
bacterial Pseudomonas aeruginosa |
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell |
| PCZA361.1 | O52791 |
bacterial Amycolatopsis orientalis |
|
| Phospholipase D | P84147 |
bacterial Streptomyces sp. |
Displaying targets 3951 - 3975 of 4170 in total